ZA200901254B - Novel engineered microorganism producing homosuccinic acid and method for preparing succinic acid using the same - Google Patents

Novel engineered microorganism producing homosuccinic acid and method for preparing succinic acid using the same

Info

Publication number
ZA200901254B
ZA200901254B ZA200901254A ZA200901254A ZA200901254B ZA 200901254 B ZA200901254 B ZA 200901254B ZA 200901254 A ZA200901254 A ZA 200901254A ZA 200901254 A ZA200901254 A ZA 200901254A ZA 200901254 B ZA200901254 B ZA 200901254B
Authority
ZA
South Africa
Prior art keywords
acid
homosuccinic
same
engineered microorganism
microorganism producing
Prior art date
Application number
ZA200901254A
Other languages
English (en)
Inventor
Sang Yup Lee
Sung Won Lim
Hyohak Song
Original Assignee
Korea Advanced Inst Sci & Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38981687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200901254(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Korea Advanced Inst Sci & Tech filed Critical Korea Advanced Inst Sci & Tech
Publication of ZA200901254B publication Critical patent/ZA200901254B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01054—Formate C-acetyltransferase (2.3.1.54), i.e. pyruvate formate-lyase or PFL
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA200901254A 2006-07-28 2009-01-22 Novel engineered microorganism producing homosuccinic acid and method for preparing succinic acid using the same ZA200901254B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020060071666A KR100780324B1 (ko) 2006-07-28 2006-07-28 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법

Publications (1)

Publication Number Publication Date
ZA200901254B true ZA200901254B (en) 2010-08-25

Family

ID=38981687

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200901254A ZA200901254B (en) 2006-07-28 2009-01-22 Novel engineered microorganism producing homosuccinic acid and method for preparing succinic acid using the same

Country Status (17)

Country Link
US (2) US9217138B2 (ja)
EP (1) EP2054502B2 (ja)
JP (1) JP5421103B2 (ja)
KR (1) KR100780324B1 (ja)
CN (1) CN101636488B (ja)
AU (1) AU2007277593B2 (ja)
BR (1) BRPI0713839B1 (ja)
CA (1) CA2659246C (ja)
DK (1) DK2054502T4 (ja)
ES (1) ES2464159T5 (ja)
MX (1) MX2009001004A (ja)
MY (1) MY162581A (ja)
NZ (1) NZ575237A (ja)
PT (1) PT2054502E (ja)
RU (1) RU2415942C2 (ja)
WO (1) WO2008013405A1 (ja)
ZA (1) ZA200901254B (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100780324B1 (ko) 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
KR101103839B1 (ko) 2007-07-12 2012-01-06 한국과학기술원 순수 숙신산 생성 변이균주 및 이를 이용한 숙신산제조방법
WO2009014289A1 (en) * 2007-07-25 2009-01-29 Korea Advanced Institute Of Science And Technology Method for preparing succinic acid using sucrose as a carbon source
EP2505637B1 (en) 2007-08-17 2019-10-09 Basf Se Novel microbial succinic acid producer
ES2559385T3 (es) 2008-12-23 2016-02-11 Basf Se Células bacterianas que tienen una derivación de glioxilato para la fabricación de ácido succínico
EP2204443B1 (en) 2008-12-23 2015-11-25 Basf Se Bacterial cells exhibiting formate dehydrogenase activity for the manufacture of suc-cinic acid
EP3505619A1 (en) 2009-02-16 2019-07-03 Basf Se Novel microbial succinic acid producers and purification of succinic acid
EP2233562A1 (en) 2009-03-24 2010-09-29 Metabolic Explorer Method for producing high amount of glycolic acid by fermentation
KR101221557B1 (ko) * 2010-08-30 2013-01-14 한국과학기술원 수크로오즈와 글리세롤을 동시에 이용하는 신규 숙신산 생성 변이 미생물 및 이를 이용한 숙신산 제조방법
WO2012109534A2 (en) * 2011-02-11 2012-08-16 Regents Of The University Of Minnesota Cells and methods for producing isobutyric acid
US9657316B2 (en) 2012-08-27 2017-05-23 Genomatica, Inc. Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,4-butanediol related thereto
US11535874B2 (en) 2012-10-22 2022-12-27 Genomatica, Inc. Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing succinate related thereto
TWI794644B (zh) 2012-12-17 2023-03-01 美商奇諾麥提卡公司 用於增加甲醇存在下之還原當量可利用性及用於製造與其相關己二酸、6-胺基己酸、己二胺或己內醯胺之微生物及方法
CN104531782A (zh) * 2014-12-31 2015-04-22 南京工业大学 一种用放线杆菌微氧发酵产丙酮酸的方法
CN104946576B (zh) * 2015-04-27 2018-03-23 中国科学院过程工程研究所 大肠杆菌基因工程菌及其构建方法和在生产丙酮酸中的应用
WO2016191142A2 (en) * 2015-05-27 2016-12-01 Verily Life Sciences Llc Nanophotonic hyperspectral/lightfield superpixel imager
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
KR102129379B1 (ko) * 2018-10-10 2020-07-02 한국과학기술원 고활성의 말산 탈수소효소가 도입된 숙신산 생성용 변이 미생물 및 이를 이용한 숙신산 제조방법

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168055A (en) * 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
EP0249773B1 (en) 1986-06-11 1992-12-16 Michigan Biotechnology Institute A process for the production of succinic acid by anaerobic fermentation
US5143834A (en) * 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5439873A (en) 1994-02-23 1995-08-08 Plant Growth Development Corporation Method for stimulating plant growth using GABA
US5521075A (en) * 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
US5573931A (en) 1995-08-28 1996-11-12 Michigan Biotechnology Institute Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants
US5770435A (en) * 1995-11-02 1998-06-23 University Of Chicago Mutant E. coli strain with increased succinic acid production
KR19990013007A (ko) 1997-07-31 1999-02-25 박원훈 형질전환된 대장균 ｓｓ373(ｋｃｔｃ 8818ｐ)과 이를 이용한숙신산의 생산방법
US7351578B2 (en) 1999-12-10 2008-04-01 Invitrogen Corp. Use of multiple recombination sites with unique specificity in recombinational cloning
JP4074365B2 (ja) 1998-01-28 2008-04-09 三菱化学株式会社 ラクテートデヒドロゲナーゼ遺伝子及び該遺伝子破壊株
US6159738A (en) 1998-04-28 2000-12-12 University Of Chicago Method for construction of bacterial strains with increased succinic acid production
CA2392753A1 (en) 1999-12-10 2001-06-14 Invitrogen Corporation Use of multiple recombination sites with unique specificity in recombinational cloning
KR100372218B1 (ko) 2000-06-29 2003-02-14 바이오인포메틱스 주식회사 유기산을 생산하는 균주 및 이를 이용한 유기산의 생산방법
US6743610B2 (en) 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
KR20050051149A (ko) * 2003-11-27 2005-06-01 한국과학기술원 루멘 박테리아 변이균주 및 이를 이용한 숙신산의 제조방법
BRPI0416437A (pt) * 2003-11-27 2007-02-21 Korea Advanced Inst Sci & Tech mutantes da bactéria do rúmen e processo para preparar ácido succìnio utilizando as mesmas
KR100630819B1 (ko) * 2004-04-23 2006-10-02 한국과학기술원 신규 루멘 박테리아 변이균주 및 이를 이용한 숙신산의제조방법
EP1781797B1 (en) 2004-08-27 2016-10-19 Rice University Mutant e. coli strain with increased succinic acid production
CN101023178A (zh) * 2004-09-17 2007-08-22 莱斯大学 高琥珀酸产出细菌
WO2006069174A2 (en) 2004-12-22 2006-06-29 Rice University Simultaneous anaerobic production of isoamyl acetate and succinic acid
KR100676160B1 (ko) 2005-08-19 2007-02-01 한국과학기술원 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
KR100727054B1 (ko) 2005-08-19 2007-06-12 한국과학기술원 푸마레이트 하이드라타제 ｃ를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
KR100679638B1 (ko) 2005-08-19 2007-02-06 한국과학기술원 포메이트 디하이드로게나제 ｄ 또는 ｅ를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법
CN101300356A (zh) 2005-09-09 2008-11-05 基因组股份公司 用于琥珀酸盐之生长关联性生产的方法和生物
KR100762962B1 (ko) 2006-05-04 2007-10-04 한국과학기술원 게놈정보 및 인실리코 분석을 이용한 배양배지의 제조방법
KR100780324B1 (ko) 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
KR101103839B1 (ko) * 2007-07-12 2012-01-06 한국과학기술원 순수 숙신산 생성 변이균주 및 이를 이용한 숙신산제조방법
EP2505637B1 (en) 2007-08-17 2019-10-09 Basf Se Novel microbial succinic acid producer
KR101221557B1 (ko) 2010-08-30 2013-01-14 한국과학기술원 수크로오즈와 글리세롤을 동시에 이용하는 신규 숙신산 생성 변이 미생물 및 이를 이용한 숙신산 제조방법

Also Published As

Publication number Publication date
EP2054502A1 (en) 2009-05-06
DK2054502T3 (da) 2014-04-28
US20160017383A1 (en) 2016-01-21
PT2054502E (pt) 2014-07-09
RU2009107208A (ru) 2010-09-10
CN101636488B (zh) 2013-07-31
BRPI0713839B1 (pt) 2017-07-04
WO2008013405A1 (en) 2008-01-31
ES2464159T3 (es) 2014-05-30
CN101636488A (zh) 2010-01-27
US9217138B2 (en) 2015-12-22
ES2464159T5 (es) 2017-10-27
NZ575237A (en) 2011-11-25
CA2659246C (en) 2014-11-25
RU2415942C2 (ru) 2011-04-10
EP2054502B2 (en) 2017-06-28
DK2054502T4 (en) 2017-09-04
EP2054502B1 (en) 2014-04-02
MY162581A (en) 2017-06-30
JP2009544335A (ja) 2009-12-17
MX2009001004A (es) 2009-05-25
US9428774B2 (en) 2016-08-30
KR100780324B1 (ko) 2007-11-29
JP5421103B2 (ja) 2014-02-19
EP2054502A4 (en) 2009-12-02
AU2007277593A1 (en) 2008-01-31
AU2007277593B2 (en) 2012-08-02
CA2659246A1 (en) 2008-01-31
US20090203095A1 (en) 2009-08-13

Similar Documents

Publication Publication Date Title
ZA200901254B (en) Novel engineered microorganism producing homosuccinic acid and method for preparing succinic acid using the same
EP2094844A4 (en) IMPROVED BUTANOL PRODUCING MICROORGANISMS AND METHOD FOR THE PRODUCTION OF BUTANOL THEREWITH
EP2060665A4 (en) POLYLACTIC ACID FIBER AND METHOD OF MANUFACTURE
EP1748062A4 (en) AMMINOIC ACID PRODUCING BACTERIUM AND METHOD FOR PRODUCING STARCHIC ACID
EP2336347A4 (en) L-amino acid-producing microorganism and method for producing L-amino acid
EP2295536A4 (en) MICROORGANISM CAPABLE OF PRODUCING IMPROVED POLYHYDROXYALCANOATE AND PROCESS FOR PRODUCING POLYHYDROXYALCANOATE USING THE SAME
HK1137156A1 (en) Headgear and process for producing the same
EP2060611A4 (en) ULTRAVIOLET RADIATION-CURABLE ADHESIVE COMPOSITION, ULTRAVIOLET-CURABLE ADHESIVE ADHESIVE SHEET AND METHOD OF MANUFACTURING THE SAME
EP1824808A4 (en) METHOD FOR PURIFYING HYDROXYCARBOXYLIC ACIDS, METHOD FOR PRODUCING CYCLIC ESTERS AND METHOD FOR PRODUCING POLYHYDROXYCARBOXYLIC ACIDS
EP2102327A4 (en) MANIPULATED MICROORGANISMS FOR THE MANUFACTURE OF N-BUTANOL AND CORRESPONDING METHODS
EP2196534A4 (en) RECOMBINANT MICROORGANISM AND METHOD FOR PRODUCING POLY GAMMA GLUTAMINE ACID
ZA201103570B (en) Microorganism for producing succinic acid
PL2108693T3 (pl) Mikroorganizm wytwarzający O-acetylohomoserynę i sposób wytwarzania O-acetylohomoseryny z zastosowaniem mikroorganizmu
EP2243770A4 (en) NOVEL DIURETHANE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ACRYLIC RUBBER COMPOSITION CONTAINING THE SAME
EP1748076A4 (en) PROCESS FOR THE MANUFACTURE OF HYDROXYCARBOXYLIC ACID
EP2327681A4 (en) FIXED BED REACTOR AND PROCESS FOR PRODUCING ACRYLIC ACID USING THE SAME
SG10201701701RA (en) Fermentation product containing equol-producing microorganism having maintained equol-producing ability, and method for producing same
EP2126043A4 (en) MICROBIOLOGIC INOCULANTS BASED ON STABLE ORGANIC CARRIER AND METHOD FOR THE PRODUCTION THEREOF
HK1122960A1 (en) A fermented dairy product and the method for producing the same
EP2222845A4 (en) MICRO-ORGANISMS FOR INCREASED ETHANOL AND BUTANOL PRODUCTION AND PROCESS FOR THE PREPARATION OF ETHANOL AND BUTANOL THEREWITH
IL198845A0 (en) Sustained-release composition and method for producing the same
IL233881A (en) Yeast genetically modified yeasts for squalene production, a genetically modified yeast yeast preparation and method for making them
EP1867714A4 (en) 5-FLUORURACIL RESISTANT BACTERIA AND METHOD FOR THE PRODUCTION THEREOF
IL193560A0 (en) Novel microorganism and method for producing dodecahydro-3a,6,6,9a-
EP2405006A4 (en) MICROORGANISM FOR THE MANUFACTURE OF L-AMINO ACIDS AND METHOD FOR THE PRODUCTION OF L-AMINO ACIDS THEREWITH