ZA200705750B - Compositions and methods for stabilizing active pharmaceutical ingredients - Google Patents

Compositions and methods for stabilizing active pharmaceutical ingredients

Info

Publication number
ZA200705750B
ZA200705750B ZA200705750A ZA200705750A ZA200705750B ZA 200705750 B ZA200705750 B ZA 200705750B ZA 200705750 A ZA200705750 A ZA 200705750A ZA 200705750 A ZA200705750 A ZA 200705750A ZA 200705750 B ZA200705750 B ZA 200705750B
Authority
ZA
South Africa
Prior art keywords
compositions
methods
active pharmaceutical
pharmaceutical ingredients
stabilizing active
Prior art date
Application number
ZA200705750A
Other languages
English (en)
Inventor
Nichols William Michael
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Publication of ZA200705750B publication Critical patent/ZA200705750B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200705750A 2004-12-13 2007-07-12 Compositions and methods for stabilizing active pharmaceutical ingredients ZA200705750B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63545004P 2004-12-13 2004-12-13

Publications (1)

Publication Number Publication Date
ZA200705750B true ZA200705750B (en) 2008-11-26

Family

ID=36129953

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200705750A ZA200705750B (en) 2004-12-13 2007-07-12 Compositions and methods for stabilizing active pharmaceutical ingredients

Country Status (15)

Country Link
US (1) US20060127473A1 (fr)
EP (1) EP1874275A1 (fr)
JP (1) JP2008523044A (fr)
KR (1) KR20080013847A (fr)
CN (1) CN101262852A (fr)
AR (1) AR052153A1 (fr)
AU (1) AU2005315291A1 (fr)
BR (1) BRPI0518553A2 (fr)
CA (1) CA2590834A1 (fr)
MX (1) MX2007007069A (fr)
NZ (1) NZ555909A (fr)
RU (1) RU2391115C2 (fr)
TW (1) TW200633716A (fr)
WO (1) WO2006064327A1 (fr)
ZA (1) ZA200705750B (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2398960T3 (es) * 2005-06-17 2013-03-22 Aft Pharmaceuticals Limited Composición farmacéutica novedosa y su uso en un método para el tratamiento de pacientes con cangestión mucosa de las vías respiratorias altas
WO2007020079A2 (fr) * 2005-08-17 2007-02-22 Synthon B.V. Comprimes de simvastatine a desintegration orale
US8940796B2 (en) 2006-02-21 2015-01-27 Wyeth Llc Phenylephrine liquid formulations
AU2007254819A1 (en) * 2006-06-01 2007-12-13 Schering Corporation Phenylphrine pulsed release formulations and pharmaceutical compositions
NZ573174A (en) * 2006-06-01 2012-01-12 Msd Consumer Care Inc Sustained release pharmaceutical dosage form containing phenylephrine
PL2034970T3 (pl) 2006-06-01 2012-12-31 Msd Consumer Care Inc Preparat farmaceutyczny o przedłużonym uwalnianiu zawierający fenylefrynę
WO2007143163A2 (fr) * 2006-06-01 2007-12-13 Schering Corporation Compositions pharmaceutiques pour la libération prolongée de phenylephrine
US9005652B2 (en) 2006-07-25 2015-04-14 Wyeth Chewable tablet containing phenylephrine
US20090068262A1 (en) * 2007-04-04 2009-03-12 Ilan Zalit Rapid dissolution of combination products
RU2009148862A (ru) * 2007-06-01 2011-07-20 Шеринг-Плау Хельскер Продактс, Инк. (Us) Фармацевтическая композиция, включающая субстрат и покрытие, содержащее активный ингридиент и поливиниловый спирт
US8323695B2 (en) * 2007-08-13 2012-12-04 Mcneil-Ppc, Inc. Method for stabilizing phenylephrine
US9078824B2 (en) * 2007-09-24 2015-07-14 The Procter & Gamble Company Composition and method of stabilized sensitive ingredient
PE20091084A1 (es) * 2007-12-07 2009-07-23 Schering Plough Healthcare Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal
US20090214665A1 (en) * 2008-02-26 2009-08-27 Lai Felix S Controlled Release Muscarinic Receptor Antagonist Formulation
PT2279731E (pt) * 2008-04-23 2013-08-30 Farmasierra Mfg S L Composição farmacêutica melhorada contendo ibuprofeno e codeína
WO2010041277A2 (fr) * 2008-10-06 2010-04-15 Jubilant Organosys Limited Compositions pharmaceutiques stables de montélukast ou de ses sels ou solvates ou hydrates
KR20110102344A (ko) * 2008-12-19 2011-09-16 노파르티스 아게 개선된 안정성을 갖는 페닐에프린 제제
US10130627B2 (en) * 2008-12-19 2018-11-20 GlaxoSmithKine Consumer Healthcare S.A. Phenylephrine formulations with improved stability
US8603527B2 (en) * 2010-10-25 2013-12-10 Signal Pharmaceuticals, Llc Pharmaceutical formulations of a substituted diaminopurine
ITMI20112221A1 (it) * 2011-12-05 2013-06-06 Altergon Sa Formulazioni stabili in capsule di gelatina molle di antiaggreganti piastrinici, acidi grassi omega-3 e amilosio
ZA201508730B (en) * 2014-12-01 2017-03-29 Michael T Rathogwa Decongestant gum
CA3001337C (fr) * 2015-10-09 2023-12-12 Reckitt Benckiser Llc Formulation pharmaceutique
CA3029985A1 (fr) * 2016-07-05 2018-01-11 Glaxosmithkline Consumer Healthcare Holdings (Us) Llc Forme galenique orale contenant un enrobage exterieur a liberation rapide
CN106727370A (zh) * 2016-12-07 2017-05-31 万全万特制药（厦门）有限公司 一种含有盐酸齐拉西酮的口崩片及其制备方法
WO2018207257A1 (fr) * 2017-05-09 2018-11-15 大塚製薬株式会社 Médicament emballé
CN108670811A (zh) * 2018-05-22 2018-10-19 河南华冠新能源科技有限公司 量子自发热温灸理疗片配方及其制备方法
WO2020150460A1 (fr) * 2019-01-18 2020-07-23 Milne Iii Donald A Formulation d'aspirine micronisée
CN110279695B (zh) * 2019-08-07 2022-04-08 北京博智绿洲医药科技有限公司 一种治疗流涕、鼻塞等感冒症状的药物组合物及其制备方法和用途
CN111214449B (zh) * 2020-03-02 2021-09-07 广东彼迪药业有限公司 一种盐酸西替利嗪片剂及其制备方法

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NL272604A (fr) * 1960-12-28
US3352752A (en) * 1963-07-25 1967-11-14 Tintex Corp Intestinal adsorbent compositions
US3337402A (en) * 1963-09-03 1967-08-22 Hoffmann La Roche Stable and palatable pharmaceutical composition
US3337403A (en) * 1963-09-05 1967-08-22 Hoffmann La Roche Stable and palatable pharmaceutical compositions
US3449266A (en) * 1964-05-25 1969-06-10 Drackett Co Stabilized solid granular perfume composition
US3272594A (en) * 1965-10-22 1966-09-13 Merck & Co Inc Preparation of magnesium trisilicate
US3567819A (en) * 1969-01-30 1971-03-02 Hoffmann La Roche Cold tablet
US3636200A (en) * 1969-06-09 1972-01-18 Hoffmann La Roche Pharmaceutical suspension
IL58462A0 (en) * 1978-10-27 1980-01-31 Beecham Group Ltd Intramammary compositions comprising a penicillin
US4327076A (en) * 1980-11-17 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US4327077A (en) * 1981-05-29 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US4581232A (en) * 1983-07-20 1986-04-08 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates
US4493827A (en) * 1983-11-14 1985-01-15 Ronald Valle Method of inducing sleep
US4910023A (en) * 1988-06-09 1990-03-20 Warner-Lambert Company Drug in combination with flavor masking agent and method for making same
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6190696B1 (en) * 1998-06-08 2001-02-20 Pieter J. Groenewoud Stabilized thyroxine medications
US6399101B1 (en) * 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
SI21221A (sl) * 2002-06-21 2003-12-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Hitro razpadljive tablete
MXPA05005781A (es) * 2002-11-29 2005-12-12 Forest Laboratories Combinacion de ibuprofeno y oxicodona para alivio de dolor agudo.
US20040162273A1 (en) * 2003-01-23 2004-08-19 The Procter & Gamble Company Powder pharmaceutical compositions
US20040265375A1 (en) * 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets

Also Published As

Publication number Publication date
CN101262852A (zh) 2008-09-10
RU2007126652A (ru) 2009-01-20
KR20080013847A (ko) 2008-02-13
AU2005315291A1 (en) 2006-06-22
JP2008523044A (ja) 2008-07-03
NZ555909A (en) 2009-11-27
WO2006064327A1 (fr) 2006-06-22
BRPI0518553A2 (pt) 2008-11-25
TW200633716A (en) 2006-10-01
RU2391115C2 (ru) 2010-06-10
CA2590834A1 (fr) 2006-06-22
EP1874275A1 (fr) 2008-01-09
AR052153A1 (es) 2007-03-07
US20060127473A1 (en) 2006-06-15
MX2007007069A (es) 2008-01-30

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