ZA200701570B - Novel polymorphs of azabicyclohexane - Google Patents

Novel polymorphs of azabicyclohexane

Info

Publication number
ZA200701570B
ZA200701570B ZA200701570A ZA200701570A ZA200701570B ZA 200701570 B ZA200701570 B ZA 200701570B ZA 200701570 A ZA200701570 A ZA 200701570A ZA 200701570 A ZA200701570 A ZA 200701570A ZA 200701570 B ZA200701570 B ZA 200701570B
Authority
ZA
South Africa
Prior art keywords
azabicyclohexane
novel polymorphs
polymorphs
novel
Prior art date
Application number
ZA200701570A
Other languages
English (en)
Inventor
Eric J Hagen
Halloran Kevin
Original Assignee
Dov Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dov Pharmaceutical Inc filed Critical Dov Pharmaceutical Inc
Publication of ZA200701570B publication Critical patent/ZA200701570B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
ZA200701570A 2004-08-18 2005-08-17 Novel polymorphs of azabicyclohexane ZA200701570B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92074804A 2004-08-18 2004-08-18

Publications (1)

Publication Number Publication Date
ZA200701570B true ZA200701570B (en) 2008-08-27

Family

ID=35968183

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200701570A ZA200701570B (en) 2004-08-18 2005-08-17 Novel polymorphs of azabicyclohexane

Country Status (14)

Country Link
EP (1) EP1786417A4 (ko)
JP (1) JP2008510715A (ko)
KR (3) KR20070054208A (ko)
CN (1) CN101052393A (ko)
AU (1) AU2005277351A1 (ko)
BR (1) BRPI0515193A (ko)
CA (1) CA2619817A1 (ko)
IL (1) IL181185A (ko)
MX (1) MX2007001827A (ko)
NO (1) NO20071372L (ko)
NZ (1) NZ589033A (ko)
RU (1) RU2007109817A (ko)
WO (1) WO2006023659A2 (ko)
ZA (1) ZA200701570B (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
EP2719384B1 (en) 2005-07-27 2018-08-08 Otsuka America Pharmaceutical, Inc. Novel 1-naphthyl-3-azabicyclo[3.1.0]hexanes:preparation and use to treat neuropsychiatric disorders
US20080045725A1 (en) * 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
AU2011336318A1 (en) * 2010-12-03 2013-07-04 Euthymics Bioscience, Inc. Preparation and use of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane in the treatment of conditions affected by monoamine neurotransmitters
EP2994129A4 (en) * 2013-05-07 2017-01-25 Euthymic Bioscience, Inc. Use of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane to treat addictive and alcohol-related disorders
KR101567003B1 (ko) 2013-12-27 2015-11-06 경희대학교 산학협력단 골편 고정장치 및 골편 절단을 위한 드릴 어셈블리
EP3310352A4 (en) 2015-06-17 2019-03-13 Otsuka America Pharmaceutical, Inc. CRYSTALLINE COMPOUNDS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4435419A (en) * 1981-07-01 1984-03-06 American Cyanamid Company Method of treating depression using azabicyclohexanes
US6372919B1 (en) * 2001-01-11 2002-04-16 Dov Pharmaceutical, Inc. (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent

Also Published As

Publication number Publication date
MX2007001827A (es) 2007-04-23
JP2008510715A (ja) 2008-04-10
IL181185A0 (en) 2007-07-04
KR20130004370A (ko) 2013-01-09
KR20070054208A (ko) 2007-05-28
KR20130108489A (ko) 2013-10-02
AU2005277351A1 (en) 2006-03-02
NO20071372L (no) 2007-05-18
BRPI0515193A (pt) 2008-07-08
IL181185A (en) 2012-10-31
NZ589033A (en) 2012-06-29
WO2006023659A2 (en) 2006-03-02
RU2007109817A (ru) 2008-09-27
WO2006023659A3 (en) 2006-12-07
CA2619817A1 (en) 2006-03-02
CN101052393A (zh) 2007-10-10
EP1786417A2 (en) 2007-05-23
EP1786417A4 (en) 2009-05-20

Similar Documents

Publication Publication Date Title
EP1778618A4 (en) SYNTHESIS OF TRIETHYLENETETRAMINES
IL181587A0 (en) Production of ??-abeta
SI1802579T1 (sl) Derivati 3-arilaminopiridina
IL182580A0 (en) Polymorphic forms of 6-[2-
EP1718638A4 (en) NEW COMPOUNDS
GB0400812D0 (en) Novel compounds
EP1711484A4 (en) SYNTHESIS OF CYANOIMINO-BENZOIMIDAZOLES
IL181185A0 (en) Novel polymorphs of azabicyclohexane
EP1804582A4 (en) POLYMORPH SHAPES OF TADALAFIL
GB0402140D0 (en) Novel compounds
IL185029A0 (en) Preparation of tadalafil intermediates
GB0402496D0 (en) Novel compounds
EP1805132A4 (en) NEW COMPOUNDS
EP1796793A4 (en) NEW CONNECTIONS
GB0402357D0 (en) Novel compounds
IL181164A0 (en) Novel uses of 2-phenyl-substituted imidazotriazinone derivatives
SI1812422T1 (sl) Kristalna oblika irbesartana
ZA200703630B (en) Polymorphs of sarsapogenin
GB0402812D0 (en) Novel compounds
GB0402355D0 (en) Novel compounds
GB0402356D0 (en) Novel compounds
IL178184A0 (en) Synthesis of pyrrole-2-carbonitriles
GB0402380D0 (en) Novel compounds
GB0404105D0 (en) Novel compounds
SI1709057T1 (sl) Sinteza spongozina