ZA200701175B - Porphyrin derivatives and their use in photon activation therapy - Google Patents

Porphyrin derivatives and their use in photon activation therapy

Info

Publication number
ZA200701175B
ZA200701175B ZA200701175A ZA200701175A ZA200701175B ZA 200701175 B ZA200701175 B ZA 200701175B ZA 200701175 A ZA200701175 A ZA 200701175A ZA 200701175 A ZA200701175 A ZA 200701175A ZA 200701175 B ZA200701175 B ZA 200701175B
Authority
ZA
South Africa
Prior art keywords
porphyrin derivatives
activation therapy
photon activation
photon
therapy
Prior art date
Application number
ZA200701175A
Other languages
English (en)
Inventor
Patel Bipin Chandra Muljibhai
Original Assignee
Psimei Pharmaceuticals Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Psimei Pharmaceuticals Plc filed Critical Psimei Pharmaceuticals Plc
Publication of ZA200701175B publication Critical patent/ZA200701175B/xx

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA200701175A 2004-07-13 2007-02-09 Porphyrin derivatives and their use in photon activation therapy ZA200701175B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0415663.4A GB0415663D0 (en) 2004-07-13 2004-07-13 Compound

Publications (1)

Publication Number Publication Date
ZA200701175B true ZA200701175B (en) 2008-11-26

Family

ID=32893498

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200701175A ZA200701175B (en) 2004-07-13 2007-02-09 Porphyrin derivatives and their use in photon activation therapy

Country Status (12)

Country Link
US (1) US7816518B2 (pt)
EP (1) EP1773324B1 (pt)
JP (1) JP2008506675A (pt)
KR (1) KR20070054636A (pt)
CN (1) CN101018551A (pt)
AU (1) AU2005261561A1 (pt)
BR (1) BRPI0513278A (pt)
CA (1) CA2573609A1 (pt)
GB (2) GB0415663D0 (pt)
RU (1) RU2007105233A (pt)
WO (1) WO2006005924A1 (pt)
ZA (1) ZA200701175B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0415663D0 (en) 2004-07-13 2004-08-18 Psimei Pharmaceuticals Plc Compound
JP4522452B2 (ja) * 2005-04-18 2010-08-11 浩 前田 高分子型癌治療用医薬およびその製造方法
US8287839B2 (en) 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8951561B2 (en) 2007-08-06 2015-02-10 Duke University Methods and systems for treating cell proliferation disorders using plasmonics enhanced photospectral therapy (PEPST) and exciton-plasmon enhanced phototherapy (EPEP)
US8324342B1 (en) * 2007-06-13 2012-12-04 Sandia Corporation Porphyrin coordination polymer nanospheres and nanorods
CN102056625B (zh) * 2008-04-04 2015-11-25 免疫之光有限责任公司 用于原位光生物调节的非侵入性系统和方法
WO2009129321A1 (en) * 2008-04-18 2009-10-22 Sonnemed Llc Compounds and methods for activated therapy
EA027923B1 (ru) * 2008-11-17 2017-09-29 Ксилеко, Инк. Переработка биомассы
WO2011099602A1 (ja) * 2010-02-12 2011-08-18 学校法人日本大学 ポルフィリン誘導体および放射線力学療法におけるその使用
HUE029083T2 (en) * 2010-10-06 2017-02-28 Aeolus Sciences Inc Treatment of neurodegenerative diseases with porphyrin
DE102010056443A1 (de) * 2010-12-28 2012-06-28 Universität Bremen Chlorin-Derivate und deren Verwendung
EP2729175B1 (en) 2011-07-08 2021-12-01 Duke University System for light stimulation within a medium
CN102499924B (zh) * 2011-11-23 2013-07-24 中国医学科学院生物医学工程研究所 二乙撑三胺五乙酸或乙二胺四乙酸或胺三乙酸修饰卟啉的用途
GB201208548D0 (en) * 2012-05-15 2012-06-27 Pci Biotech As Compound and method
EP3061762A1 (en) * 2015-02-26 2016-08-31 Universiteit van Amsterdam Photosensitizers
CN105503918A (zh) * 2015-12-08 2016-04-20 南京林业大学 一种含二氧杂戊硼基卟啉锌配合物及其制备方法
WO2019117457A1 (ko) 2017-12-12 2019-06-20 한국과학기술원 다공성 포르피린 고분자 및 이를 이용한 귀금속 원소의 회수 방법
KR102193582B1 (ko) * 2017-12-12 2020-12-22 한국과학기술원 다공성 포르피린 고분자 및 이를 이용한 귀금속 원소의 회수 방법
CN109679110B (zh) * 2018-12-25 2020-10-09 北京科技大学 一种基于菌绿素的纳米金属-有机框架光敏剂及制备方法
CN110684531B (zh) * 2019-10-09 2022-04-01 浙江理工大学 一种二硫化钼量子点负载四苯基锆卟啉纳米片的光敏传感材料的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5489716A (en) 1987-01-02 1996-02-06 Sun Company, Inc. (R&M) Reactions catalyzed by haloporphyrins
US4959356A (en) * 1989-05-26 1990-09-25 The United States Of America As Represented By The United States Department Of Energy Porphyrins for boron neutron capture therapy
JP3191223B2 (ja) * 1991-10-04 2001-07-23 株式会社光ケミカル研究所 ポルフィリン誘導体とその用途
JP3253663B2 (ja) * 1992-01-20 2002-02-04 タマ生化学株式会社 放射線増感剤
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use
EP0983272B1 (en) * 1997-05-07 2003-10-29 University Of British Columbia A new class of benzoporphyrin derivative photoactive compounds
JP2004532251A (ja) 2001-05-31 2004-10-21 ミラヴァント ファーマシューティカルズ インコーポレイテッド 光線力学療法で使用のメタロテトラピロール系光増感剤
JP4247110B2 (ja) * 2001-06-06 2009-04-02 ブルックヘブン サイエンス アソシエーツ 新規メタロポルフィリン及び放射線治療用放射線増感剤としてのそれらの使用
GB0227259D0 (en) 2002-11-21 2002-12-31 Photobiotics Ltd Porphyrin derivatives
US7378520B2 (en) 2004-07-08 2008-05-27 North Carolina State University Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers
GB0415663D0 (en) 2004-07-13 2004-08-18 Psimei Pharmaceuticals Plc Compound

Also Published As

Publication number Publication date
US20080039436A1 (en) 2008-02-14
AU2005261561A1 (en) 2006-01-19
EP1773324B1 (en) 2015-04-01
RU2007105233A (ru) 2008-08-20
BRPI0513278A (pt) 2008-05-06
WO2006005924A1 (en) 2006-01-19
EP1773324A1 (en) 2007-04-18
KR20070054636A (ko) 2007-05-29
GB0415663D0 (en) 2004-08-18
GB0702696D0 (en) 2007-03-21
GB2433070A (en) 2007-06-13
CN101018551A (zh) 2007-08-15
JP2008506675A (ja) 2008-03-06
US7816518B2 (en) 2010-10-19
CA2573609A1 (en) 2006-01-19

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