ZA200609261B - Fused quinoline derivative and use thereof - Google Patents
Fused quinoline derivative and use thereofInfo
- Publication number
- ZA200609261B ZA200609261B ZA200609261A ZA200609261A ZA200609261B ZA 200609261 B ZA200609261 B ZA 200609261B ZA 200609261 A ZA200609261 A ZA 200609261A ZA 200609261 A ZA200609261 A ZA 200609261A ZA 200609261 B ZA200609261 B ZA 200609261B
- Authority
- ZA
- South Africa
- Prior art keywords
- substituent
- optionally
- group optionally
- acyl
- hydrogen atom
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Anesthesiology (AREA)
- Ophthalmology & Optometry (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004134705 | 2004-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200609261B true ZA200609261B (en) | 2008-08-27 |
Family
ID=34966886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200609261A ZA200609261B (en) | 2004-04-28 | 2005-04-28 | Fused quinoline derivative and use thereof |
Country Status (28)
Country | Link |
---|---|
US (4) | US7592453B2 (xx) |
EP (2) | EP1740584B9 (xx) |
JP (2) | JP4361566B2 (xx) |
KR (1) | KR20070015598A (xx) |
CN (1) | CN1976932A (xx) |
AT (1) | ATE416176T1 (xx) |
AU (1) | AU2005238388B2 (xx) |
BR (1) | BRPI0510365A (xx) |
CA (1) | CA2565018A1 (xx) |
CR (1) | CR8755A (xx) |
CY (1) | CY1109222T1 (xx) |
DE (1) | DE602005011424D1 (xx) |
DK (1) | DK1740584T5 (xx) |
ES (1) | ES2318483T4 (xx) |
HK (1) | HK1099284A1 (xx) |
HR (1) | HRP20090121T5 (xx) |
MX (1) | MXPA06012323A (xx) |
MY (1) | MY143370A (xx) |
NO (1) | NO20065494L (xx) |
NZ (1) | NZ550983A (xx) |
PL (1) | PL1740584T3 (xx) |
PT (1) | PT1740584E (xx) |
RS (1) | RS50756B (xx) |
RU (1) | RU2384571C2 (xx) |
SI (1) | SI1740584T1 (xx) |
TW (1) | TW200540155A (xx) |
WO (1) | WO2005105802A1 (xx) |
ZA (1) | ZA200609261B (xx) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS50756B (sr) * | 2004-04-28 | 2010-08-31 | Takeda Pharmaceutical Company Limited | Fuzionisani derivati hinolina i njegova upotreba |
EP1765789B1 (en) * | 2004-06-18 | 2013-02-27 | Novartis AG | N-(1-(1-benzyl-4-phenyl-1h-imidazol-2-yl)-2,2-dimethylpropyl)benzamide derivatives and related compounds as kinesin spindle protein (ksp) inhibitors for the treatment of cancer |
CA2584342C (en) | 2004-10-20 | 2013-04-30 | The Regents Of The University Of California | Improved inhibitors for the soluble epoxide hydrolase |
DE102005027170A1 (de) * | 2005-06-13 | 2006-12-14 | Merck Patent Gmbh | Substituierte Tetrahydrochinoline |
GB0522715D0 (en) | 2005-11-08 | 2005-12-14 | Helperby Therapeutics Ltd | New use |
WO2007074491A1 (en) * | 2005-12-28 | 2007-07-05 | Universita Degli Studi Di Siena | HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS |
JP4509080B2 (ja) * | 2006-09-28 | 2010-07-21 | 信越化学工業株式会社 | シルセスキオキサン系化合物混合物及び加水分解性シラン化合物、その製造方法及びそれを用いたレジスト組成物並びにパターン形成方法及び基板の加工方法 |
CA2672494A1 (en) | 2006-12-14 | 2008-06-19 | Nps Pharmaceuticals, Inc. | Use of d-serine derivatives for the treatment of anxiety disorders |
WO2008109991A1 (en) | 2007-03-09 | 2008-09-18 | University Health Network | Inhibitors of carnitine palmitoyltransferase and treating cancer |
DE102007013856A1 (de) | 2007-03-20 | 2008-09-25 | Merck Patent Gmbh | Substituierte Tetrahydropyrrolochinoline |
WO2008153027A1 (ja) * | 2007-06-11 | 2008-12-18 | Takeda Pharmaceutical Company Limited | ピロロキノリン誘導体およびその用途 |
WO2009015485A1 (en) * | 2007-08-01 | 2009-02-05 | University Health Network | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer |
TW200930713A (en) | 2007-12-03 | 2009-07-16 | Takeda Pharmaceutical | Nitrogen-containing heterocyclic compound and use thereof |
TWI498115B (zh) | 2007-12-27 | 2015-09-01 | Daiichi Sankyo Co Ltd | 咪唑羰基化合物 |
USRE49686E1 (en) | 2008-09-19 | 2023-10-10 | Takeda Pharmaceutical Company Limited | Nitrogen-containing heterocyclic compound and use of same |
JP2011256110A (ja) * | 2008-09-30 | 2011-12-22 | Takeda Chem Ind Ltd | ヘキサヒドロピロロキノリンの製造法 |
WO2010038434A1 (ja) * | 2008-09-30 | 2010-04-08 | 武田薬品工業株式会社 | 光学活性なヘキサヒドロピロロキノリン類の製造法およびその中間体 |
US20100190747A1 (en) | 2009-01-27 | 2010-07-29 | Hideo Suzuki | Fused ring compound and use thereof |
JP2013053070A (ja) * | 2009-11-06 | 2013-03-21 | Takeda Chem Ind Ltd | ジヒドロピロロキノリン誘導体 |
WO2011084848A2 (en) * | 2010-01-07 | 2011-07-14 | Alkermes, Inc. | Prodrugs of heteraromatic compounds |
FR2974729B1 (fr) * | 2011-05-02 | 2013-04-19 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide et un inhibiteur de l'acetylcholinesterase et les compositions pharmaceutiques qui la contiennent |
EP2647638A1 (en) * | 2012-04-02 | 2013-10-09 | Almirall, S.A. | Substituted tricyclic compounds with activity towards ep1 receptors |
CN105017266B (zh) * | 2015-07-17 | 2017-07-18 | 安徽农业大学 | 手性2‑芳基‑1,2,3,4‑四氢喹啉类化合物及其合成方法 |
TWI773118B (zh) * | 2016-02-12 | 2022-08-01 | 美商細胞動力學股份有限公司 | 四氫異喹啉衍生物 |
US11787795B2 (en) | 2016-11-01 | 2023-10-17 | President And Fellows Of Harvard College | Inhibitors of RNA guided nucleases and uses thereof |
US11352357B2 (en) | 2019-11-27 | 2022-06-07 | Sumitomo Dainippon Pharma Co., Ltd. | Cycloalkylurea derivative |
MX2022006422A (es) * | 2019-11-27 | 2022-08-25 | Sumitomo Pharma Co Ltd | Derivado de cicloalquilurea. |
US11530218B2 (en) | 2020-01-20 | 2022-12-20 | Incyte Corporation | Spiro compounds as inhibitors of KRAS |
WO2021231526A1 (en) | 2020-05-13 | 2021-11-18 | Incyte Corporation | Fused pyrimidine compounds as kras inhibitors |
US11767320B2 (en) | 2020-10-02 | 2023-09-26 | Incyte Corporation | Bicyclic dione compounds as inhibitors of KRAS |
US11738021B2 (en) * | 2021-08-23 | 2023-08-29 | Ckp Therapeutics, Inc. | Composition and method for preventing, alleviating or treating cancer |
US11939328B2 (en) | 2021-10-14 | 2024-03-26 | Incyte Corporation | Quinoline compounds as inhibitors of KRAS |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5288725A (en) * | 1992-10-15 | 1994-02-22 | Merck & Co., Inc. | Pyrroloquinoline Bradykinin antagonist |
IT1283171B1 (it) | 1996-03-01 | 1998-04-16 | Interdipartimentale Di Ricerca | Composti solubili antagonisti delle tachichinine loro preparazione e loro uso in composizioni farmaceutiche |
JP2004517062A (ja) * | 2000-11-13 | 2004-06-10 | グラクソスミスクライン・ソシエタ・ペル・アチオニ | Nk−3およびnk−2アンタゴニストとしてのキノリン誘導体 |
GB0027701D0 (en) | 2000-11-13 | 2000-12-27 | Smithkline Beecham Spa | Novel compounds |
JP2004525183A (ja) | 2001-04-11 | 2004-08-19 | グラクソスミスクライン・ソシエタ・ペル・アチオニ | Nk−3およびnk−2受容体アンタゴニストとしてのキノリン−4−カルボキサミド誘導体 |
JP2004134705A (ja) | 2002-10-15 | 2004-04-30 | Jiaotong Univ | 金属酸化膜半導体電界効果トランジスタおよびそのゲート構造 |
RS50756B (sr) * | 2004-04-28 | 2010-08-31 | Takeda Pharmaceutical Company Limited | Fuzionisani derivati hinolina i njegova upotreba |
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2005
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- 2005-04-28 KR KR1020067024809A patent/KR20070015598A/ko not_active Application Discontinuation
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- 2005-04-28 WO PCT/JP2005/008558 patent/WO2005105802A1/en active Application Filing
- 2005-04-28 CA CA002565018A patent/CA2565018A1/en not_active Abandoned
- 2005-04-28 ES ES05738868T patent/ES2318483T4/es active Active
- 2005-04-28 NZ NZ550983A patent/NZ550983A/en unknown
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- 2005-04-28 AT AT05738868T patent/ATE416176T1/de active
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- 2005-04-28 AU AU2005238388A patent/AU2005238388B2/en not_active Expired - Fee Related
- 2005-04-28 CN CNA200580021496XA patent/CN1976932A/zh active Pending
- 2005-04-28 DK DK05738868.8T patent/DK1740584T5/da active
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- 2005-04-28 EP EP05738868A patent/EP1740584B9/en active Active
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- 2005-04-28 MX MXPA06012323A patent/MXPA06012323A/es active IP Right Grant
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