ZA200608798B - Macrocyclic compounds as inhibitors of viral replication - Google Patents

Macrocyclic compounds as inhibitors of viral replication

Info

Publication number
ZA200608798B
ZA200608798B ZA200608798A ZA200608798A ZA200608798B ZA 200608798 B ZA200608798 B ZA 200608798B ZA 200608798 A ZA200608798 A ZA 200608798A ZA 200608798 A ZA200608798 A ZA 200608798A ZA 200608798 B ZA200608798 B ZA 200608798B
Authority
ZA
South Africa
Prior art keywords
inhibitors
viral replication
macrocyclic compounds
macrocyclic
compounds
Prior art date
Application number
ZA200608798A
Other languages
English (en)
Inventor
Lawrence M Blatt
Yutong Jiang
Steven M Wenglowsky
Steven W Andrews
Kevin R Condroski
April L Kennedy
George A Doherty
John A Josey
Peter J Stengel
Machender R Madduru
Benjamin T Woodard
Original Assignee
Intermune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intermune Inc filed Critical Intermune Inc
Publication of ZA200608798B publication Critical patent/ZA200608798B/xx

Links

ZA200608798A 2004-03-30 2006-10-23 Macrocyclic compounds as inhibitors of viral replication ZA200608798B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55816104P 2004-03-30 2004-03-30

Publications (1)

Publication Number Publication Date
ZA200608798B true ZA200608798B (en) 2008-06-25

Family

ID=37955155

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200608798A ZA200608798B (en) 2004-03-30 2006-10-23 Macrocyclic compounds as inhibitors of viral replication

Country Status (5)

Country Link
CN (1) CN1938311A (es)
CU (1) CU20090112A6 (es)
TN (1) TNSN06308A1 (es)
UA (1) UA91677C2 (es)
ZA (1) ZA200608798B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2191274A1 (en) * 2007-09-10 2010-06-02 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research Method for predicting the response of a subject suffering from a viral infection of the liver to an antiviral therapy
RS53350B (en) 2008-09-22 2014-10-31 Array Biopharma, Inc. SUBSTITUTED COMPOUNDS OF IMIDASO [1,2-B] PYRIDASINE AS INK KINASE INHIBITORS
TWI577680B (zh) 2008-10-22 2017-04-11 亞雷生物製藥股份有限公司 作為ＴＲＫ激酶抑制劑之經取代吡唑并〔１，５－ａ〕嘧啶化合物
CA2753667C (en) * 2009-02-27 2015-11-17 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. Amorphous salt of a macrocyclic inhibitor of hcv
AR077468A1 (es) 2009-07-09 2011-08-31 Array Biopharma Inc Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
US20110129444A1 (en) * 2009-09-28 2011-06-02 Intermune, Inc Novel macrocyclic inhibitors of hepatitis c virus replication
BR112012018897A2 (pt) * 2010-01-27 2017-10-03 Ab Pharma Ltd Compostos poli-heterocíclicos altamente potentes como inibidores de hcv
ES2534335T3 (es) 2010-05-20 2015-04-21 Array Biopharma, Inc. Compuestos macrocíclicos como inhibidores de la Trk cinasa
GB201116559D0 (en) * 2011-09-26 2011-11-09 Univ Leuven Kath Novel viral replication inhibitors
FI3699181T3 (fi) 2014-11-16 2023-03-28 Array Biopharma Inc Kiteinen muoto (s)-n-(5-((r)-2-(2,5-diluorifenyyli)-pyrrolidin-1-yyli)-pyratsolo[1,5-a]pyrimidin-3-yyli)-3-hydroksipyrrolidiini-1-karboksamidivetyysulfaatista
MX2018005087A (es) 2015-10-26 2019-05-16 Loxo Oncology Inc Mutaciones puntuales en cáncer resistente a trk y métodos relacionados con las mismas.
CN107043405B (zh) * 2016-02-05 2021-11-19 爱博新药研发(上海)有限公司 多环杂环化合物的晶型、其制备方法、应用及组合物
US10045991B2 (en) 2016-04-04 2018-08-14 Loxo Oncology, Inc. Methods of treating pediatric cancers
JP7061602B2 (ja) 2016-04-04 2022-04-28 ロクソ オンコロジー， インコーポレイテッド （Ｓ）－Ｎ－（５－（（Ｒ）－２－（２，５－ジフルオロフェニル）－ピロリジン－１－イル）－ピラゾロ［１，５－ａ］ピリミジン－３－イル）－３－ヒドロキシピロリジン－１－カルボキサミドの液体製剤
DK3458456T3 (da) 2016-05-18 2020-12-14 Array Biopharma Inc Fremstilling af (s)-n-(5-((r)-2-(2,5-difluorphenyl)pyrrolidin-1-yl)pyrazol[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidin-1-carboxamid
JOP20190092A1 (ar) 2016-10-26 2019-04-25 Array Biopharma Inc عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها
JOP20190213A1 (ar) 2017-03-16 2019-09-16 Array Biopharma Inc مركبات حلقية ضخمة كمثبطات لكيناز ros1

Also Published As

Publication number Publication date
UA91677C2 (ru) 2010-08-25
TNSN06308A1 (en) 2007-12-03
CN1938311A (zh) 2007-03-28
CU20090112A6 (es) 2012-03-15

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