ZA200608798B - Macrocyclic compounds as inhibitors of viral replication - Google Patents

Macrocyclic compounds as inhibitors of viral replication

Info

Publication number
ZA200608798B
ZA200608798B ZA200608798A ZA200608798A ZA200608798B ZA 200608798 B ZA200608798 B ZA 200608798B ZA 200608798 A ZA200608798 A ZA 200608798A ZA 200608798 A ZA200608798 A ZA 200608798A ZA 200608798 B ZA200608798 B ZA 200608798B
Authority
ZA
South Africa
Prior art keywords
inhibitors
viral replication
macrocyclic compounds
macrocyclic
compounds
Prior art date
Application number
ZA200608798A
Other languages
English (en)
Inventor
Lawrence M Blatt
Yutong Jiang
Steven M Wenglowsky
Steven W Andrews
Kevin R Condroski
April L Kennedy
George A Doherty
John A Josey
Peter J Stengel
Machender R Madduru
Benjamin T Woodard
Original Assignee
Intermune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intermune Inc filed Critical Intermune Inc
Publication of ZA200608798B publication Critical patent/ZA200608798B/xx

Links

ZA200608798A 2004-03-30 2006-10-23 Macrocyclic compounds as inhibitors of viral replication ZA200608798B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55816104P 2004-03-30 2004-03-30

Publications (1)

Publication Number Publication Date
ZA200608798B true ZA200608798B (en) 2008-06-25

Family

ID=37955155

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200608798A ZA200608798B (en) 2004-03-30 2006-10-23 Macrocyclic compounds as inhibitors of viral replication

Country Status (5)

Country Link
CN (1) CN1938311A (es)
CU (1) CU20090112A6 (es)
TN (1) TNSN06308A1 (es)
UA (1) UA91677C2 (es)
ZA (1) ZA200608798B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101821629A (zh) * 2007-09-10 2010-09-01 诺瓦提斯研究基金会弗里德里克·米谢尔生物医学研究所 用于预测患有肝脏病毒性感染的受试者针对抗病毒疗法的应答的方法
US8450322B2 (en) 2008-09-22 2013-05-28 Array Biopharma Inc. Substituted imidazo[1,2b]pyridazine compounds as Trk kinase inhibitors
AR074052A1 (es) 2008-10-22 2010-12-22 Array Biopharma Inc Compuestos pirazolo{1,5-a}pirimidina sustituida como inhibidores de trk cinasa
MX340792B (es) * 2009-02-27 2016-07-25 Ortho-Mcneil-Janssen Pharmaceuticals Inc * Sal amorfa de un inhibidor macrociclico de virus de hepatitis c.
AR077468A1 (es) 2009-07-09 2011-08-31 Array Biopharma Inc Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
CN102712644A (zh) * 2009-09-28 2012-10-03 豪夫迈·罗氏有限公司 丙肝病毒复制的新型大环抑制剂
KR101781789B1 (ko) * 2010-01-27 2017-09-26 에이비 파르마 리미티드. C형 간염 바이러스 억제제로 사용되는 다환 헤테로사이클릭 화합물
CR20170098A (es) 2010-05-20 2017-07-17 Array Biopharma Inc Compuestos macrociclicos como inhibidores de quinasa trk
GB201116559D0 (en) * 2011-09-26 2011-11-09 Univ Leuven Kath Novel viral replication inhibitors
JP6914834B2 (ja) 2014-11-16 2021-08-04 アレイ バイオファーマ インコーポレイテッド （Ｓ）−Ｎ−（５−（（Ｒ）−２−（２，５−ジフルオロフェニル）−ピロリジン−１−イル）−ピラゾロ［１，５−ａ］ピリミジン−３−イル）−３−ヒドロキシピロリジン−１−カルボキサミド硫酸水素塩の結晶形
AU2016344058A1 (en) 2015-10-26 2018-05-17 Array Biopharma Inc. Point mutations in Trk inhibitor-resistant cancer and methods relating to the same
CN107043405B (zh) * 2016-02-05 2021-11-19 爱博新药研发(上海)有限公司 多环杂环化合物的晶型、其制备方法、应用及组合物
RU2751767C2 (ru) 2016-04-04 2021-07-16 Локсо Онколоджи, Инк. Жидкие составы (s)-n-(5-((r)-2-(2,5-дифторфенил)пирролидин-1-ил)пиразоло[1,5-a]пиримидин-3-ил)-3-гидроксипирролидин-1-карбоксамида
US10045991B2 (en) 2016-04-04 2018-08-14 Loxo Oncology, Inc. Methods of treating pediatric cancers
KR102566858B1 (ko) 2016-05-18 2023-08-11 어레이 바이오파마 인크. (s)-n-(5-((r)-2-(2,5-디플루오로페닐)피롤리딘-1-일)-피라졸로[1,5-a]피리미딘-3-일)-3-히드록시피롤리딘-1-카르복사미드의 제조 방법
JOP20190092A1 (ar) 2016-10-26 2019-04-25 Array Biopharma Inc عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها
JOP20190213A1 (ar) 2017-03-16 2019-09-16 Array Biopharma Inc مركبات حلقية ضخمة كمثبطات لكيناز ros1

Also Published As

Publication number Publication date
CU20090112A6 (es) 2012-03-15
CN1938311A (zh) 2007-03-28
UA91677C2 (ru) 2010-08-25
TNSN06308A1 (en) 2007-12-03

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