TNSN06308A1 - Macrocyclic compounds as inhibitors of viral replication - Google Patents

Macrocyclic compounds as inhibitors of viral replication

Info

Publication number
TNSN06308A1
TNSN06308A1 TNP2006000308A TNSN06308A TNSN06308A1 TN SN06308 A1 TNSN06308 A1 TN SN06308A1 TN P2006000308 A TNP2006000308 A TN P2006000308A TN SN06308 A TNSN06308 A TN SN06308A TN SN06308 A1 TNSN06308 A1 TN SN06308A1
Authority
TN
Tunisia
Prior art keywords
methods
inhibitors
viral replication
macrocyclic compounds
subject compound
Prior art date
Application number
TNP2006000308A
Other languages
English (en)
French (fr)
Inventor
Steven M Wenglowsky
Steven W Andrews
Kevin R Condroski
Yutong Jiang
April L Kennedy
George A Doherty
John A Josey
Peter J Stengel
Benjamin T Woodard
Machender R Madduru
Lawrence M Blatt
Original Assignee
Intermune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2005/010494 external-priority patent/WO2005095403A2/en
Application filed by Intermune Inc filed Critical Intermune Inc
Publication of TNSN06308A1 publication Critical patent/TNSN06308A1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TNP2006000308A 2004-03-30 2006-09-27 Macrocyclic compounds as inhibitors of viral replication TNSN06308A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55816104P 2004-03-30 2004-03-30
PCT/US2005/010494 WO2005095403A2 (en) 2004-03-30 2005-03-29 Macrocyclic compounds as inhibitors of viral replication

Publications (1)

Publication Number Publication Date
TNSN06308A1 true TNSN06308A1 (en) 2007-12-03

Family

ID=37955155

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2006000308A TNSN06308A1 (en) 2004-03-30 2006-09-27 Macrocyclic compounds as inhibitors of viral replication

Country Status (5)

Country Link
CN (1) CN1938311A (es)
CU (1) CU20090112A6 (es)
TN (1) TNSN06308A1 (es)
UA (1) UA91677C2 (es)
ZA (1) ZA200608798B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2191274A1 (en) * 2007-09-10 2010-06-02 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research Method for predicting the response of a subject suffering from a viral infection of the liver to an antiviral therapy
RS53350B (en) 2008-09-22 2014-10-31 Array Biopharma, Inc. SUBSTITUTED COMPOUNDS OF IMIDASO [1,2-B] PYRIDASINE AS INK KINASE INHIBITORS
TWI577680B (zh) 2008-10-22 2017-04-11 亞雷生物製藥股份有限公司 作為ＴＲＫ激酶抑制劑之經取代吡唑并〔１，５－ａ〕嘧啶化合物
CA2753667C (en) * 2009-02-27 2015-11-17 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. Amorphous salt of a macrocyclic inhibitor of hcv
AR077468A1 (es) 2009-07-09 2011-08-31 Array Biopharma Inc Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
US20110129444A1 (en) * 2009-09-28 2011-06-02 Intermune, Inc Novel macrocyclic inhibitors of hepatitis c virus replication
BR112012018897A2 (pt) * 2010-01-27 2017-10-03 Ab Pharma Ltd Compostos poli-heterocíclicos altamente potentes como inibidores de hcv
ES2534335T3 (es) 2010-05-20 2015-04-21 Array Biopharma, Inc. Compuestos macrocíclicos como inhibidores de la Trk cinasa
GB201116559D0 (en) * 2011-09-26 2011-11-09 Univ Leuven Kath Novel viral replication inhibitors
FI3699181T3 (fi) 2014-11-16 2023-03-28 Array Biopharma Inc Kiteinen muoto (s)-n-(5-((r)-2-(2,5-diluorifenyyli)-pyrrolidin-1-yyli)-pyratsolo[1,5-a]pyrimidin-3-yyli)-3-hydroksipyrrolidiini-1-karboksamidivetyysulfaatista
MX2018005087A (es) 2015-10-26 2019-05-16 Loxo Oncology Inc Mutaciones puntuales en cáncer resistente a trk y métodos relacionados con las mismas.
CN107043405B (zh) * 2016-02-05 2021-11-19 爱博新药研发(上海)有限公司 多环杂环化合物的晶型、其制备方法、应用及组合物
US10045991B2 (en) 2016-04-04 2018-08-14 Loxo Oncology, Inc. Methods of treating pediatric cancers
JP7061602B2 (ja) 2016-04-04 2022-04-28 ロクソ オンコロジー， インコーポレイテッド （Ｓ）－Ｎ－（５－（（Ｒ）－２－（２，５－ジフルオロフェニル）－ピロリジン－１－イル）－ピラゾロ［１，５－ａ］ピリミジン－３－イル）－３－ヒドロキシピロリジン－１－カルボキサミドの液体製剤
DK3458456T3 (da) 2016-05-18 2020-12-14 Array Biopharma Inc Fremstilling af (s)-n-(5-((r)-2-(2,5-difluorphenyl)pyrrolidin-1-yl)pyrazol[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidin-1-carboxamid
JOP20190092A1 (ar) 2016-10-26 2019-04-25 Array Biopharma Inc عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها
JOP20190213A1 (ar) 2017-03-16 2019-09-16 Array Biopharma Inc مركبات حلقية ضخمة كمثبطات لكيناز ros1

Also Published As

Publication number Publication date
UA91677C2 (ru) 2010-08-25
ZA200608798B (en) 2008-06-25
CN1938311A (zh) 2007-03-28
CU20090112A6 (es) 2012-03-15

Similar Documents

Publication Publication Date Title
WO2005095403A3 (en) Macrocyclic compounds as inhibitors of viral replication
TNSN06308A1 (en) Macrocyclic compounds as inhibitors of viral replication
SG166791A1 (en) Novel macrocyclic inhibitors of hepatitis c virus replication
TN2009000457A1 (en) Novel macrocyclic inhibitors of hepatitis c virus replication
WO2007047146A3 (en) Inhibitors of viral replication
WO2008005511A8 (en) Novel inhibitors of hepatitis c virus replication
TN2009000481A1 (en) Novel peptide inhibitors of hepatitis c virus replication
WO2009142842A3 (en) Novel macrocyclic inhibitors of hepatitis c virus replication
MY144593A (en) Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
MX2012003171A (es) Novedosos inhibidores macrociclicos de la replicacion del virus de hepatitis c.
WO2006039488A3 (en) Hcv ns3-ns4a protease inhibition
WO2008100867A3 (en) Novel inhibitors hepatitis c virus replication
WO2008106058A3 (en) Inhibitors of serine proteases
WO2009134616A8 (en) Novel inhibitors of hepatitis c virus replication
TNSN06103A1 (en) Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
TW200611905A (en) Macrocyclic compounds as inhibitors of viral replication
UA95455C2 (ru) Макроциклические ингибиторы репликации вируса гепатита с
UA84579C2 (ru) Макроциклические карбоновые кислоты и ацилсульфонамиды как ингибиторы репликации вируса гепатита с
TN2010000468A1 (en) Novel macrocyclic inhibitors of hepatitis c virus replication
CU23602A3 (es) Compuestos macrocíclicos como inhibidores de la replicación viral