ZA200605299B - Control of parasites in animals by the use of imidazo [1,2-B]pyridazine derivatives - Google Patents

Control of parasites in animals by the use of imidazo [1,2-B]pyridazine derivatives

Info

Publication number
ZA200605299B
ZA200605299B ZA200605299A ZA200605299A ZA200605299B ZA 200605299 B ZA200605299 B ZA 200605299B ZA 200605299 A ZA200605299 A ZA 200605299A ZA 200605299 A ZA200605299 A ZA 200605299A ZA 200605299 B ZA200605299 B ZA 200605299B
Authority
ZA
South Africa
Prior art keywords
animals
imidazo
parasites
control
pyridazine derivatives
Prior art date
Application number
ZA200605299A
Other languages
English (en)
Inventor
Kevin N Winzenberg
Craig L Francis
David G Sawutz
Ganguly Ashit
Original Assignee
Schering Plough Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Ltd filed Critical Schering Plough Ltd
Publication of ZA200605299B publication Critical patent/ZA200605299B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA200605299A 2003-12-31 2006-06-27 Control of parasites in animals by the use of imidazo [1,2-B]pyridazine derivatives ZA200605299B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53372903P 2003-12-31 2003-12-31

Publications (1)

Publication Number Publication Date
ZA200605299B true ZA200605299B (en) 2007-03-28

Family

ID=34748949

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200605299A ZA200605299B (en) 2003-12-31 2006-06-27 Control of parasites in animals by the use of imidazo [1,2-B]pyridazine derivatives

Country Status (15)

Country Link
US (1) US7759349B2 (enExample)
EP (1) EP1699799B1 (enExample)
JP (1) JP4758909B2 (enExample)
KR (1) KR20060110344A (enExample)
CN (1) CN100582108C (enExample)
AT (1) ATE362475T1 (enExample)
AU (1) AU2004312506B2 (enExample)
BR (1) BRPI0418328A (enExample)
CA (1) CA2551867C (enExample)
DE (1) DE602004006536T2 (enExample)
ES (1) ES2285565T3 (enExample)
NZ (1) NZ548098A (enExample)
PL (1) PL380764A1 (enExample)
WO (1) WO2005066177A1 (enExample)
ZA (1) ZA200605299B (enExample)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943160B2 (en) * 2002-05-09 2011-05-17 Scimetrics Limited Corp. Pest control methods
US7312248B2 (en) 2004-09-23 2007-12-25 Schering-Plough Animal Health Corporation Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
MX2007006072A (es) 2004-11-19 2007-07-11 Schering Plough Ltd Control de parasitos en animales mediante el uso de derivados del parasiticida 2-fenil-3-(1h-pirrol-2-il)acrilonitrilo.
WO2006070943A1 (ja) * 2004-12-28 2006-07-06 Takeda Pharmaceutical Company Limited 縮合イミダゾール化合物およびその用途
MX2007015729A (es) * 2005-06-09 2008-02-21 Schering Plough Ltd Control de parasitos en animales con derivados de n-[(feniloxi)fenil]-1,1,1-trifluorometansulfonamida y de n[(fenilsulfanil)fenil]-1,1,1-trifluorometansulfonamida.
DE102005042742A1 (de) * 2005-09-02 2007-03-08 Schering Ag Substituierte Imidazo[1,2b]pyridazine als Kinase-Inhibitoren, deren Herstellung und Verwendung als Arzneimittel
US7750000B2 (en) 2005-09-02 2010-07-06 Bayer Schering Pharma Ag Substituted imidazo[1,2b]pyridazines as kinase inhibitors, their preparation and use as medicaments
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
RU2008150377A (ru) * 2006-05-19 2010-06-27 Нихон Меди-Физикс Ко., Лтд. (Jp) Новое соединение, обладающее сродством к амилоиду
DE102006029447A1 (de) * 2006-06-21 2007-12-27 Bayer Schering Pharma Ag Oxo-substituierte Imidazo[1,2b]pyridazine, deren Herstellung und Verwendung als Arzneimittel
KR20090025282A (ko) 2006-06-21 2009-03-10 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
AR062207A1 (es) * 2006-08-04 2008-10-22 Takeda Pharmaceutical Derivados de imidazopiridazina inhibidores de quinasas utiles para prevenir y/o tratar el cancer.
CN101595108A (zh) * 2006-11-30 2009-12-02 日本医事物理股份有限公司 对淀粉状蛋白具有亲和性的新化合物
EP2102154A1 (en) * 2006-12-13 2009-09-23 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
WO2008076259A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of florfenicol and its analogs
WO2008072682A1 (ja) * 2006-12-15 2008-06-19 Daiichi Sankyo Company, Limited イミダゾ[1,2-b]ピリダジン誘導体
CN101636183B (zh) 2007-02-13 2014-03-19 日本医事物理股份有限公司 放射性诊断显像剂的制备方法
WO2008133192A1 (ja) * 2007-04-19 2008-11-06 Takeda Pharmaceutical Company Limited 縮合イミダゾール化合物およびその用途
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
LT2957284T (lt) 2007-06-27 2018-04-10 E. I. Du Pont De Nemours And Company Kovos su gyvūnų kenkėjais būdas
CA2694261A1 (en) * 2007-07-26 2009-01-29 Novartis Ag Organic compounds
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
CN101903381A (zh) * 2007-10-24 2010-12-01 日本医事物理股份有限公司 对淀粉样蛋白具有亲和性的新化合物
US20100249419A1 (en) * 2007-10-30 2010-09-30 Nihon Medi-Physics Co., Ltd. Utilization of novel compounds with amyloid affinity and method of producing the same
CN101909657A (zh) * 2007-10-30 2010-12-08 日本医事物理股份有限公司 对淀粉样蛋白具有亲和性的新化合物的应用及制备方法
US7868001B2 (en) 2007-11-02 2011-01-11 Hutchison Medipharma Enterprises Limited Cytokine inhibitors
TWI491610B (zh) * 2008-10-09 2015-07-11 必治妥美雅史谷比公司 作為激酶抑制劑之咪唑并嗒腈
WO2011017347A2 (en) 2009-08-05 2011-02-10 E. I. Du Pont De Nemours And Company Mesoionic pesticides
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
BR112012002519A2 (pt) 2009-08-05 2019-09-24 Du Pont "pesticidas mesoiônicos"
AU2011212478B2 (en) 2010-02-05 2014-11-06 Intervet International B.V. Spiroindoline Compounds For Use as Anthelminthics
BR112013006953A2 (pt) 2010-09-29 2016-07-26 Intervet Int Bv composto, composições farmacêutica e anti-helmíntica, uso de um composto, kit, e, método de tratamento de uma doença
CN103189356B (zh) 2010-09-29 2015-11-25 英特维特国际股份有限公司 N-杂芳基化合物
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
TWI617559B (zh) * 2010-12-22 2018-03-11 江蘇恆瑞醫藥股份有限公司 2-芳基咪唑并[1,2-b]嗒.2-苯基咪唑并[1,2-a]吡啶,和2-苯基咪唑并[1,2-a]吡衍生物
EP2721006A1 (en) 2011-06-20 2014-04-23 E. I. Du Pont de Nemours and Company Heterocyclic compounds for treating helminth infections
US9096599B2 (en) 2011-08-04 2015-08-04 Intervet Inc. Spiroindoline compounds
KR20140094026A (ko) 2011-11-28 2014-07-29 이 아이 듀폰 디 네모아 앤드 캄파니 N-(4-퀴놀리닐메틸) 설폰아미드 유도체 및 구충제로서의 이의 용도
ES2744597T3 (es) 2012-03-28 2020-02-25 Intervet Int Bv Compuestos de heteroarilo con una unidad acíclica como puente
WO2013144180A1 (en) 2012-03-28 2013-10-03 Intervet International B.V. Heteroaryl compounds with cyclic bridging unit for use in the treatment helminth infection
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
WO2014099837A1 (en) 2012-12-18 2014-06-26 E. I. Du Pont De Nemours And Company Sulfonamide anthelmintics
BR112017021408B1 (pt) 2015-04-08 2022-05-17 Bayer Cropscience Aktiengesellschaft Derivados de heterociclo bicíclico condensado, método para controlar pragas animais, e formulação agroquímica
TW201718514A (zh) 2015-08-07 2017-06-01 拜耳作物科學股份有限公司 作為殺蟲劑之經2-(雜)芳基取代之稠合雜環衍生物
RU2018119344A (ru) 2015-10-26 2019-11-28 Байер Кропсайенс Акциенгезельшафт Конденсированные бициклические гетероциклические производные в качестве средства для борьбы с вредителями
WO2017093180A1 (de) 2015-12-01 2017-06-08 Bayer Cropscience Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
WO2017144341A1 (de) 2016-02-23 2017-08-31 Bayer Cropscience Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
WO2017174414A1 (de) 2016-04-05 2017-10-12 Bayer Cropscience Aktiengesellschaft Naphthalin-derivate als schädlingsbekämpfungsmittel
EP3241830A1 (de) 2016-05-04 2017-11-08 Bayer CropScience Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
KR102435080B1 (ko) * 2016-07-19 2022-08-22 바이엘 크롭사이언스 악티엔게젤샤프트 해충 방제제로서의 축합 바이시클릭 헤테로사이클 유도체
MX2019001918A (es) 2016-08-15 2019-09-06 Bayer Cropscience Ag Derivados del heterociclo biciclico condensado como agentes de control de plagas.
TW201825499A (zh) 2016-09-19 2018-07-16 德商拜耳作物科學股份有限公司 作為殺蟲劑之稠合雙環雜環衍生物
WO2018065288A1 (de) 2016-10-07 2018-04-12 Bayer Cropscience Aktiengesellschaft 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz
JP7098630B2 (ja) 2017-01-10 2022-07-11 バイエル・アクチエンゲゼルシヤフト 有害生物防除剤としてのヘテロサイクレン誘導体
KR102515694B1 (ko) 2017-01-10 2023-03-29 바이엘 악티엔게젤샤프트 해충 방제제로서의 헤테로사이클 유도체
GB201700692D0 (en) * 2017-01-16 2017-03-01 Salvensis Novel compounds and their use in the treatment of schistosomiasis
WO2018138050A1 (de) 2017-01-26 2018-08-02 Bayer Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
EP3615540B1 (de) 2017-04-24 2022-04-27 Bayer Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
EP3305786A3 (de) 2018-01-22 2018-07-25 Bayer CropScience Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
KR20200122353A (ko) 2018-02-21 2020-10-27 바이엘 악티엔게젤샤프트 해충 방제제로서의 축합 바이시클릭 헤테로시클릭 유도체
WO2020002593A1 (en) 2018-06-29 2020-01-02 Intervet International B.V. Compound for use against helminthic infection
WO2020014068A1 (en) 2018-07-09 2020-01-16 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic heterocyclic compounds
CN113710669A (zh) 2019-02-26 2021-11-26 拜耳公司 作为农药的稠合双环杂环衍生物
MX2021010217A (es) 2019-02-26 2021-09-21 Bayer Ag Derivados heterociclos biciclicos condensados como plaguicida.
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
CA3164098A1 (en) 2019-12-18 2021-06-24 Intervet International B.V. Anthelmintic compounds comprising a quinoline structure
WO2021122906A1 (en) 2019-12-18 2021-06-24 Intervet International B.V. Anthelmintic compounds comprising azaindoles structure
AU2021278889A1 (en) * 2020-05-29 2023-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anthelmintic heterocyclic compounds
GB202019622D0 (en) * 2020-12-11 2021-01-27 Adorx Therapeutics Ltd Antagonist compounds
US20240043446A1 (en) 2020-12-11 2024-02-08 Intervet Inc. Anthelmintic compounds comprising a thienopyridine structure
WO2025027117A1 (en) 2023-08-02 2025-02-06 Intervet International B.V. Carboxamide-4-quinoline compounds with anthelmintic activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725407A (en) * 1971-04-08 1973-04-03 American Cyanamid Co 6-substituted amino-3-nitroimidazo(1,2-b)pyridazines and methods of preparing the same
US3905974A (en) * 1972-09-28 1975-09-16 American Cyanamid Co 6-Substituted oxo and thio-3-nitroimidazo(1,2-b)-pyridazines and methods of preparing same
DD157796A5 (de) 1979-12-04 1982-12-08 Ciba Geigy Ag Verfahren zur herstellung neuer derivate des 2-amino-aethanols

Also Published As

Publication number Publication date
ES2285565T3 (es) 2007-11-16
AU2004312506B2 (en) 2011-08-04
US20050182059A1 (en) 2005-08-18
CA2551867C (en) 2010-08-17
DE602004006536D1 (de) 2007-06-28
US7759349B2 (en) 2010-07-20
EP1699799A1 (en) 2006-09-13
NZ548098A (en) 2010-05-28
WO2005066177A1 (en) 2005-07-21
CA2551867A1 (en) 2005-07-21
HK1091207A1 (en) 2007-01-12
EP1699799B1 (en) 2007-05-16
KR20060110344A (ko) 2006-10-24
DE602004006536T2 (de) 2008-01-31
ATE362475T1 (de) 2007-06-15
AU2004312506A1 (en) 2005-07-21
PL380764A1 (pl) 2007-03-19
CN100582108C (zh) 2010-01-20
JP2007517043A (ja) 2007-06-28
CN1922181A (zh) 2007-02-28
JP4758909B2 (ja) 2011-08-31
BRPI0418328A (pt) 2007-05-02

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