ZA200603804B - CD40 antibody formulation and methods - Google Patents

CD40 antibody formulation and methods Download PDF

Info

Publication number
ZA200603804B
ZA200603804B ZA200603804A ZA200603804A ZA200603804B ZA 200603804 B ZA200603804 B ZA 200603804B ZA 200603804 A ZA200603804 A ZA 200603804A ZA 200603804 A ZA200603804 A ZA 200603804A ZA 200603804 B ZA200603804 B ZA 200603804B
Authority
ZA
South Africa
Prior art keywords
antibody
patient
administered
tumor
medicament
Prior art date
Application number
ZA200603804A
Other languages
English (en)
Inventor
Bedian Vahe
Cusmano John Daniel
Gladue Ronald Paul
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34738672&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200603804(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA200603804B publication Critical patent/ZA200603804B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200603804A 2003-12-22 2006-05-12 CD40 antibody formulation and methods ZA200603804B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53163903P 2003-12-22 2003-12-22

Publications (1)

Publication Number Publication Date
ZA200603804B true ZA200603804B (en) 2007-09-26

Family

ID=34738672

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200603804A ZA200603804B (en) 2003-12-22 2006-05-12 CD40 antibody formulation and methods

Country Status (20)

Country Link
US (4) US20050136055A1 (fr)
EP (3) EP2218461B1 (fr)
JP (3) JP2007515469A (fr)
KR (2) KR20080023766A (fr)
CN (2) CN102552905A (fr)
AU (1) AU2004308749B2 (fr)
BR (1) BRPI0418029B8 (fr)
CA (2) CA2549652C (fr)
DK (1) DK2218461T3 (fr)
ES (1) ES2580002T3 (fr)
HU (1) HUE027717T2 (fr)
IL (2) IL175540A (fr)
NO (1) NO343797B1 (fr)
NZ (2) NZ547162A (fr)
PL (1) PL2218461T3 (fr)
RU (1) RU2355421C2 (fr)
SI (1) SI2218461T1 (fr)
TW (1) TWI359671B (fr)
WO (1) WO2005063289A1 (fr)
ZA (1) ZA200603804B (fr)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
US7658924B2 (en) * 2001-10-11 2010-02-09 Amgen Inc. Angiopoietin-2 specific binding agents
AU2006329944A1 (en) * 2005-12-09 2007-07-05 Seattle Genetics, Inc. Methods of using CD40 binding agents
CN104357469B (zh) * 2006-05-03 2018-10-26 科罗拉多州立大学董事会 Cd40激动剂抗体/1型干扰素协同佐剂组合、包含前述的结合物及其用途
US20090074711A1 (en) * 2006-09-07 2009-03-19 University Of Southhampton Human therapies using chimeric agonistic anti-human cd40 antibody
WO2008150494A1 (fr) 2007-05-30 2008-12-11 Xencor, Inc. Procédés et compositions permettant l'inhibition de cellules d'expression du cd32b
JO2913B1 (en) * 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
EP2323690A1 (fr) * 2008-08-29 2011-05-25 Academisch Ziekenhuis Leiden h.o.d.n. LUMC Administration d un agoniste de cd40 à un ganglion lymphatique drainant une tumeur d un sujet
US9561214B2 (en) * 2008-10-16 2017-02-07 Array Biopharma Inc. Method of treatment using inhibitors of mitosis
WO2011101332A1 (fr) 2010-02-16 2011-08-25 Proyecto De Biomedicina Cima, S.L. Compositions basées sur le domaine extracellulaire a de fibronectine pour le traitement d'un mélanome
WO2012123269A1 (fr) 2011-03-11 2012-09-20 Proyecto De Biomedicina Cima, S.L. Compositions immunigènes et procédés pour leur utilisation
EP2505640A1 (fr) 2011-03-29 2012-10-03 Neo Virnatech, S.L. Compositions de vaccins pour maladies provoquées par le birnavirus
WO2012149356A2 (fr) 2011-04-29 2012-11-01 Apexigen, Inc. Anticorps anti-cd40 et leurs procédés d'utilisation
PL2844282T3 (pl) 2012-05-04 2019-11-29 Pfizer Antygeny związane z gruczołem krokowym i schematy immunoterapii oparte na szczepionce
FR2994390B1 (fr) 2012-08-10 2014-08-15 Adocia Procede d'abaissement de la viscosite de solutions de proteines a concentration elevee
CN110066335B (zh) 2012-10-30 2024-04-05 埃派斯进有限公司 抗-cd40抗体及其使用方法
US9856319B2 (en) 2012-12-28 2018-01-02 Abbvie Inc. Monovalent binding proteins
EP2951209A4 (fr) 2013-01-31 2016-06-22 Univ Jefferson Protéine de fusion agoniste des cd40 ox40 et ses utilisations
SI3030575T1 (sl) 2013-08-08 2018-11-30 Cytune Pharma Modulokini na osnovi IL-15 in IL-15R-alfa sushi domene
KR20170072884A (ko) 2014-10-29 2017-06-27 시애틀 지네틱스, 인크. 비-푸코실화된 항-cd40 항체의 용량 및 투여
CN111375066B (zh) 2015-07-16 2023-04-25 百欧肯治疗有限公司 治疗癌症的组合物及方法
EP3426271A4 (fr) 2016-03-10 2019-10-16 Cold Genesys, Inc. Méthodes de traitement de tumeurs solides ou lymphatiques par polythérapie
DK3468997T3 (da) 2016-06-08 2023-10-02 Xencor Inc Behandling af IgG4-relaterede sygdomme med anti-CD9-antistoffer med tværbinding til CD32B
TWI640536B (zh) 2016-06-20 2018-11-11 克馬伯有限公司 抗體
CN110546164B (zh) * 2016-11-11 2023-10-20 锦湖Ht株式会社 特异性结合cd40的抗体及其用途
WO2018162450A1 (fr) 2017-03-06 2018-09-13 Fundación Para La Investigación Médica Aplicada Nouvelles compositions immunostimulatrices comprenant une entité protéine de liaison à l'arn inductible à froid (cirp)-antigène pour l'activation des cellules dendritiques
EP3632933A4 (fr) 2017-06-01 2021-03-03 Seoul National University R & DB Foundation Nouveaux anticorps anti-cd40 et leur utilisation
WO2018220100A1 (fr) * 2017-06-02 2018-12-06 F. Hoffmann-La Roche Ag Voies d'administration pour des agonistes immunitaires
EP3418302A1 (fr) * 2017-06-19 2018-12-26 F. Hoffmann-La Roche AG Voies d'administration d'agonistes immunitaires
JP2021521804A (ja) * 2018-04-20 2021-08-30 リビジェン バイオファーマ カンパニー リミテッド 抗cd40抗体およびその使用
CA3103629A1 (fr) 2018-06-15 2019-12-19 Flagship Pioneering Innovations V, Inc. Augmentation de l'activite immunitaire par modulation de facteurs de signalisation post-cellulaires
CN112996818B (zh) 2018-09-28 2022-06-21 礼进生物医药科技(上海)有限公司 具有经过工程化的Fc结构域的抗CD40结合分子及其治疗用途
AU2019388931A1 (en) * 2018-11-30 2021-07-15 Jiangsu Hengrui Medicine Co., Ltd. CD40 antibody pharmaceutical composition and use thereof
MA55805A (fr) 2019-05-03 2022-03-09 Flagship Pioneering Innovations V Inc Métodes de modulation de l'activité immunitaire
US20230114107A1 (en) 2019-12-17 2023-04-13 Flagship Pioneering Innovations V, Inc. Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly
JP2023514727A (ja) 2020-02-21 2023-04-07 シルバーバック セラピューティックス インコーポレイテッド ネクチン-4抗体コンジュゲートおよびその使用
CA3184366A1 (fr) 2020-06-29 2022-01-06 Darby Rye Schmidt Virus modifies pour favoriser la thanotransmission et leur utilisation dans le traitement du cancer
TW202216211A (zh) 2020-07-01 2022-05-01 美商希沃爾拜克治療公司 抗asgr1抗體共軛物及其用途
AU2022246895A1 (en) 2021-03-31 2023-10-19 Flagship Pioneering Innovations V, Inc. Thanotransmission polypeptides and their use in treating cancer
AU2022303363A1 (en) 2021-06-29 2024-01-18 Flagship Pioneering Innovations V, Inc. Immune cells engineered to promote thanotransmission and uses thereof
WO2024077191A1 (fr) 2022-10-05 2024-04-11 Flagship Pioneering Innovations V, Inc. Molécules d'acide nucléique codant pour des trif et des polypeptides supplémentaires et leur utilisation dans le traitement du cancer

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5247069A (en) * 1986-06-13 1993-09-21 Oncogen Ligands and methods for augmenting B-cell proliferation
JP2547556B2 (ja) * 1987-02-06 1996-10-23 株式会社 ミドリ十字 r−グロブリンの液状製剤
SE8701004D0 (sv) 1987-03-11 1987-03-11 Astra Ab Method for therapy of leukemias and certain other malignancies
JPH03204821A (ja) * 1989-12-28 1991-09-06 Green Cross Corp:The モノクローナル抗体含有水溶液の加熱処理方法
IL104684A0 (en) * 1992-02-14 1993-06-10 Bristol Myers Squibb Co The cd40cr receptor and ligands therefor
WO1994004570A1 (fr) 1992-08-21 1994-03-03 Schering Corporation Ligand cd40, anticorps anti-cd40, et cd40 soluble
KR960704576A (ko) * 1993-10-01 1996-10-09 크리스토퍼 엘. 와이트 CD40에 대한 항체(Antibodies to CD40)
US5674492A (en) * 1993-12-23 1997-10-07 Immunex Corporation Method of preventing or treating disease characterized by neoplastic cells expressing CD40
GB9425060D0 (en) 1994-12-13 1995-02-08 Univ Birmingham Carcinoma treatment
US6267958B1 (en) * 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
ES2190087T3 (es) * 1997-06-13 2003-07-16 Genentech Inc Formulacion estabilizada de un anticuerpo.
MXPA01012388A (es) * 1999-06-01 2002-07-30 Biogen Inc Anticuerpo monoclonal bloqueador para vla-1 y su uso para el tratamiento de trastornos inflamatorios.
AU2228901A (en) * 1999-12-28 2001-07-09 Chugai Seiyaku Kabushiki Kaisha Stable antibody compositions and injection preparations
US6358670B1 (en) * 1999-12-28 2002-03-19 Electron Vision Corporation Enhancement of photoresist plasma etch resistance via electron beam surface cure
US7172759B2 (en) 2000-02-01 2007-02-06 Pangenetics Bv Induction of cytotoxic T lymphocyte responses using anti-CD40 antibodies
US6838250B2 (en) 2000-03-31 2005-01-04 Ortho-Clinical Diagnostics, Inc. Immunoassay for C-reactive protein
US6896885B2 (en) * 2000-03-31 2005-05-24 Biogen Idec Inc. Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for treatment of B cell lymphoma
US20030059427A1 (en) 2000-04-28 2003-03-27 Force Walker R. Isolation and characterization of highly active anti-CD40 antibody
US7063845B2 (en) * 2000-04-28 2006-06-20 Gemini Science, Inc. Human anti-CD40 antibodies
US7015194B2 (en) * 2000-05-10 2006-03-21 Novo Nordisk A/S Pharmaceutical composition comprising factor VIIa and anti-TFPI
DE60143535D1 (de) * 2000-10-02 2011-01-05 Novartis Vaccines & Diagnostic Humane antikörper gegen cd40
IL155002A0 (en) * 2000-10-12 2003-10-31 Genentech Inc Reduced-viscosity concentrated protein formulations
IL149701A0 (en) * 2001-05-23 2002-11-10 Pfizer Prod Inc Use of anti-ctla-4 antibodies
US20030113316A1 (en) * 2001-07-25 2003-06-19 Kaisheva Elizabet A. Stable lyophilized pharmaceutical formulation of IgG antibodies
CN1292655C (zh) * 2001-11-08 2007-01-03 蛋白质设计实验室股份有限公司 IgG抗体稳定的液态药物制剂
AR039067A1 (es) * 2001-11-09 2005-02-09 Pfizer Prod Inc Anticuerpos para cd40
ATE395413T1 (de) * 2001-12-03 2008-05-15 Amgen Fremont Inc Antikörperkategorisierung auf der grundlage von bindungseigenschaften
US7115108B2 (en) 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US20080009439A1 (en) * 2002-11-05 2008-01-10 Alsobrook John P Compositions and Methods of Use for a Fibroblast Growth Factor
HN2004000285A (es) * 2003-08-04 2006-04-27 Pfizer Prod Inc ANTICUERPOS DIRIGIDOS A c-MET

Also Published As

Publication number Publication date
EP1706143A1 (fr) 2006-10-04
AU2004308749A1 (en) 2005-07-14
NO20063373L (no) 2006-09-21
US20110104182A1 (en) 2011-05-05
BRPI0418029B1 (pt) 2018-12-26
BRPI0418029A (pt) 2007-04-17
AU2004308749B2 (en) 2010-10-28
EP2218461A1 (fr) 2010-08-18
CA2704300A1 (fr) 2005-07-14
IL175540A (en) 2011-10-31
CA2549652A1 (fr) 2005-07-14
US20120263732A1 (en) 2012-10-18
NZ547162A (en) 2010-03-26
CA2549652C (fr) 2013-11-12
RU2006120950A (ru) 2008-01-27
JP2011184446A (ja) 2011-09-22
DK2218461T3 (en) 2016-05-17
JP5634321B2 (ja) 2014-12-03
NZ583179A (en) 2011-06-30
HUE027717T2 (en) 2016-10-28
IL175540A0 (en) 2006-09-05
EP3081933A1 (fr) 2016-10-19
EP2218461B1 (fr) 2016-04-20
TWI359671B (en) 2012-03-11
KR20070012626A (ko) 2007-01-26
TW200521142A (en) 2005-07-01
IL201409A0 (en) 2010-05-31
CN1897971A (zh) 2007-01-17
NO343797B1 (no) 2019-06-11
SI2218461T1 (sl) 2016-08-31
CN102552905A (zh) 2012-07-11
KR20080023766A (ko) 2008-03-14
JP2014205692A (ja) 2014-10-30
PL2218461T3 (pl) 2016-09-30
KR100847944B1 (ko) 2008-07-22
US20050136055A1 (en) 2005-06-23
RU2355421C2 (ru) 2009-05-20
JP2007515469A (ja) 2007-06-14
BRPI0418029B8 (pt) 2021-05-25
US20090311254A1 (en) 2009-12-17
WO2005063289A1 (fr) 2005-07-14
ES2580002T3 (es) 2016-08-18

Similar Documents

Publication Publication Date Title
AU2004308749B2 (en) CD40 antibody formulation and methods
KR20190136076A (ko) 암 치료 방법에 사용하기 위한 인터루킨-2 면역접합체, cd40 작용제 및 임의적인 pd-1 축 결합 길항제
US20220008515A1 (en) Method of treating a tumor with a combination of il-7 protein and an immune checkpoint inhibitor
KR20220042067A (ko) Gm-csf 길항제를 사용한 암의 치료
US20210277135A1 (en) Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a method of treating a cancer or a solid tumor
JP7422070B2 (ja) 癌の治療のための配合剤
WO2020049534A1 (fr) Agoniste de sting et polythérapie correspondante pour le traitement du cancer
MXPA06006153A (en) Cd40 antibody formulation and methods
WO2023199235A1 (fr) Régimes posologiques pour agents anti-cd19 et leurs utilisations
TW202216193A (zh) 包含抗CD19抗體及阻斷SIRPα-CD47先天免疫檢查點之多肽之抗腫瘤組合療法
TW201713346A (zh) 調控免疫反應之方法及抗體