ZA200603590B - Strains of microorganisms optimized for biosynthetic pathways consuming NADPH - Google Patents
Strains of microorganisms optimized for biosynthetic pathways consuming NADPH Download PDFInfo
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- ZA200603590B ZA200603590B ZA200603590A ZA200603590A ZA200603590B ZA 200603590 B ZA200603590 B ZA 200603590B ZA 200603590 A ZA200603590 A ZA 200603590A ZA 200603590 A ZA200603590 A ZA 200603590A ZA 200603590 B ZA200603590 B ZA 200603590B
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- coli
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- 230000028070 sporulation Effects 0.000 description 1
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- 230000000087 stabilizing effect Effects 0.000 description 1
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- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical compound [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
- 101150003389 tdh2 gene Proteins 0.000 description 1
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- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
- C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/12—Acting on D ring
- C12P33/16—Acting at 17 position
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0313056A FR2862068B1 (fr) | 2003-11-06 | 2003-11-06 | Souches de microorganismes optimisees pour des voies de biosyntheses consommatrices de nadph |
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| ZA200603590B true ZA200603590B (en) | 2007-07-25 |
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| ZA200603590A ZA200603590B (en) | 2003-11-06 | 2006-05-05 | Strains of microorganisms optimized for biosynthetic pathways consuming NADPH |
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| JP (1) | JP5553956B2 (es) |
| KR (1) | KR101149566B1 (es) |
| CN (2) | CN103952335B (es) |
| AT (1) | ATE529504T1 (es) |
| AU (1) | AU2004289859B2 (es) |
| BR (1) | BRPI0415774B1 (es) |
| CA (1) | CA2544507A1 (es) |
| DK (1) | DK1680504T3 (es) |
| ES (1) | ES2371648T3 (es) |
| FR (1) | FR2862068B1 (es) |
| IL (1) | IL174890A0 (es) |
| RU (1) | RU2006119625A (es) |
| WO (1) | WO2005047498A1 (es) |
| ZA (1) | ZA200603590B (es) |
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| ES2341264T3 (es) * | 2004-08-10 | 2010-06-17 | Ajinomoto Co., Inc. | El uso de fosfocetolasa para producir metabolitos utiles. |
| RU2004124226A (ru) | 2004-08-10 | 2006-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Использование фосфокетолазы для продукции полезных метаболитов |
| WO2007140816A1 (en) * | 2006-06-09 | 2007-12-13 | Metabolic Explorer | Glycolic acid production by fermentation from renewable resources |
| WO2008013996A2 (en) * | 2006-07-27 | 2008-01-31 | Gevo Inc. | Engineered microorganisms for increasing product yield in biotransformations, related methods and systems |
| CN101903513B (zh) * | 2007-01-12 | 2013-08-21 | 科罗拉多大学董事会法人 | 增强微生物对产生的有机化学物质的耐受性的组合物和方法 |
| WO2008091627A2 (en) * | 2007-01-22 | 2008-07-31 | Genomatica, Inc. | Methods and organisms for growth-coupled production of 3-hydroxypropionic acid |
| US20090215137A1 (en) * | 2007-10-31 | 2009-08-27 | Gevo, Inc. | Methods for the economical production of biofuel precursor that is also a biofuel from biomass |
| US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
| US7803589B2 (en) | 2008-01-22 | 2010-09-28 | Genomatica, Inc. | Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol |
| WO2009111672A1 (en) | 2008-03-05 | 2009-09-11 | Genomatica, Inc. | Primary alcohol producing organisms |
| WO2009135074A2 (en) | 2008-05-01 | 2009-11-05 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
| WO2010022763A1 (en) * | 2008-08-25 | 2010-03-04 | Metabolic Explorer | Method for the preparation of 2-hydroxy-isobutyrate |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| EP2350298A1 (en) * | 2008-10-27 | 2011-08-03 | ButamaxTM Advanced Biofuels LLC | Carbon pathway optimized production hosts for the production of isobutanol |
| CA2779262C (en) * | 2008-10-31 | 2021-09-07 | Gevo, Inc. | Engineered microorganisms capable of converting pyruvate to isobutanol under anaerobic conditions |
| CN102341502B (zh) | 2008-12-31 | 2015-07-01 | 代谢探索者公司 | 用于制备二醇的方法 |
| JP2012525156A (ja) | 2009-04-30 | 2012-10-22 | ゲノマチカ， インク． | イソプロパノール、ｎ−ブタノール、及びイソブタノールの産生のための微生物 |
| CA3042565A1 (en) | 2009-04-30 | 2010-11-04 | Genomatica, Inc. | Microorganism expressing exogenous crotonase for producing 1,3-butanediol |
| EP3190174A1 (en) | 2009-08-05 | 2017-07-12 | Genomatica, Inc. | Semi-synthetic terephthalic acid via microorganisms that produce muconic acid |
| US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
| CN102695799A (zh) | 2009-09-27 | 2012-09-26 | Opx生物工艺学公司 | 用于制备3-羟基丙酸和其它产物的方法 |
| BR112012009332A2 (pt) | 2009-10-23 | 2015-09-15 | Genomatica Inc | micro-organismo para a produção de anilina |
| WO2011052482A1 (ja) * | 2009-10-29 | 2011-05-05 | 三井化学株式会社 | イソプロピルアルコール生産細菌及びイソプロピルアルコール生産方法 |
| WO2011063363A2 (en) * | 2009-11-20 | 2011-05-26 | Opx Biotechnologies, Inc. | Production of an organic acid and/or related chemicals |
| EP2529011A4 (en) | 2010-01-29 | 2015-07-15 | Genomatica Inc | MICROORGANISMS AND METHODS FOR BIOSYNTHESIS OF P-TOLUATE AND TEREPHTHALATE |
| AU2011235307A1 (en) * | 2010-03-31 | 2012-08-23 | E. I. Du Pont De Nemours And Company | Pentose phosphate pathway upregulation to increase production of non-native products of interest in transgenic microorganisms |
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| TWI500768B (zh) | 2010-07-05 | 2015-09-21 | Metabolic Explorer Sa | 由蔗糖製備１，３－丙二醇之方法 |
| JP2013535203A (ja) | 2010-07-26 | 2013-09-12 | ジェノマティカ・インコーポレイテッド | 芳香族、２，４−ペンタジエノエートおよび１，３−ブタジエンを生合成するための微生物および方法 |
| AR083468A1 (es) * | 2010-10-25 | 2013-02-27 | Metabolic Explorer Sa | Aumento de la disponibilidad de nadph para la produccion de metionina |
| KR20120108538A (ko) * | 2011-03-24 | 2012-10-05 | 삼성전자주식회사 | 말로닉 세미알데히드 환원 경로를 이용한 3-하이드록시프로피온산의 생산방법 |
| US20120247066A1 (en) | 2011-04-01 | 2012-10-04 | Ice House America, Llc | Ice bagging apparatus and methods |
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| EP2540834A1 (en) | 2011-06-29 | 2013-01-02 | Metabolic Explorer | Method for the preparation of 1,3-propanediol |
| HUE032394T2 (en) | 2011-07-29 | 2017-09-28 | Mitsui Chemicals Inc | Microorganism with carbon dioxide fixation pathway introduced |
| US9410164B2 (en) | 2011-10-11 | 2016-08-09 | Metabolic Explorer | Biosynthesis pathway for prenol in a recombinant microorganism |
| EP2647718A3 (en) | 2012-04-06 | 2014-12-24 | Metabolic Explorer | Process for producing 5-aminopentanoate empolying a recombinant microorganism |
| US9181568B2 (en) | 2012-04-23 | 2015-11-10 | Exxonmobil Research And Engineering Company | Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases |
| CN104718282A (zh) | 2012-08-10 | 2015-06-17 | Opx生物工艺学公司 | 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法 |
| WO2014049382A2 (en) | 2012-09-26 | 2014-04-03 | Metabolic Explorer | Ethylenediamine fermentative production by a recombinant microorganism |
| CN104822824A (zh) * | 2012-10-15 | 2015-08-05 | 凯利斯塔公司 | 用于烃的生物氧化的遗传工程改造的微生物 |
| US9828618B2 (en) | 2013-01-24 | 2017-11-28 | Mitsui Chemicals, Inc. | Microorganism having carbon dioxide fixation cycle introduced thereinto |
| CA2905602A1 (en) | 2013-03-15 | 2014-09-18 | Sarah M. Hoyt | Flash evaporation for product purification and recovery |
| US10047383B2 (en) | 2013-03-15 | 2018-08-14 | Cargill, Incorporated | Bioproduction of chemicals |
| CN103205391A (zh) * | 2013-04-12 | 2013-07-17 | 浙江大学 | 一种基因工程菌及其应用 |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| EP3022310B1 (en) | 2013-07-19 | 2019-10-16 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| AU2014306074B2 (en) | 2013-08-05 | 2018-08-30 | Greenlight Biosciences, Inc. | Engineered proteins with a protease cleavage site |
| CN103710396A (zh) * | 2013-12-30 | 2014-04-09 | 南京工业大学 | 一种提高厌氧发酵目标产物转化率的方法 |
| EP3143148B1 (en) * | 2014-05-12 | 2024-01-03 | METabolic EXplorer | New microorganism and method for the production of 1.2-propanediol based on nadph dependent acetol reductase and improved nadph supply |
| EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
| EP3050970B1 (en) | 2015-01-28 | 2019-09-18 | Metabolic Explorer | Modified microorganism for optimized production of 1,4-butanediol |
| WO2016162712A1 (en) | 2015-04-07 | 2016-10-13 | Metabolic Explorer | Modified microorganism for the optimized production of 2,4-dihydroxyburyrate |
| EP3280794B1 (en) | 2015-04-07 | 2020-05-27 | Metabolic Explorer | A modified microorganism for the optimized production of 2,4-dihydroxyburyrate with enhanced 2,4-dihydroxybutyrate efflux |
| US10731137B2 (en) | 2015-09-10 | 2020-08-04 | Metabolic Explorer | Lactaldehyde reductases for the production of 1,2-propanediol |
| CN106086082B (zh) * | 2016-06-01 | 2019-11-15 | 苏州华赛生物工程技术有限公司 | 一种改良重组大肠杆菌生产9-癸烯醇的方法 |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| EP3342873A1 (en) | 2016-12-29 | 2018-07-04 | Metabolic Explorer | Conversion of methylglyoxal into hydroxyacetone using enzymes and applications thereof |
| CN110494566A (zh) | 2017-02-02 | 2019-11-22 | 嘉吉公司 | 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞 |
| EP3428282A1 (en) * | 2017-07-11 | 2019-01-16 | Alderys | Ectoine-producing yeast |
| KR101894984B1 (ko) * | 2017-07-14 | 2018-09-05 | 한국과학기술원 | 환원력이 증가된 캔디다 속 변이 균주 및 이의 용도 |
| CN115747240A (zh) * | 2022-08-05 | 2023-03-07 | 华熙生物科技股份有限公司 | 一种生产雌马酚的重组大肠杆菌工程菌株及应用 |
| CN117487681A (zh) * | 2023-11-16 | 2024-02-02 | 湖南农业大学 | 一种生产角鲨烯的酵母工程菌及其应用 |
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| GB9614618D0 (en) * | 1996-07-11 | 1996-09-04 | Animal Health Inst | Vaccine compositions |
| JP4380029B2 (ja) * | 2000-07-05 | 2009-12-09 | 味の素株式会社 | 微生物を利用した物質の製造法 |
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- 2004-11-05 CA CA002544507A patent/CA2544507A1/fr not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| RU2006119625A (ru) | 2007-12-27 |
| CN103952335A (zh) | 2014-07-30 |
| EP1680504A1 (fr) | 2006-07-19 |
| IL174890A0 (en) | 2006-08-20 |
| JP5553956B2 (ja) | 2014-07-23 |
| WO2005047498A1 (fr) | 2005-05-26 |
| KR101149566B1 (ko) | 2012-07-05 |
| CA2544507A1 (fr) | 2005-05-26 |
| JP2007510411A (ja) | 2007-04-26 |
| EP1680504B1 (fr) | 2011-10-19 |
| KR20060132577A (ko) | 2006-12-21 |
| US20070087403A1 (en) | 2007-04-19 |
| AU2004289859A1 (en) | 2005-05-26 |
| ATE529504T1 (de) | 2011-11-15 |
| ES2371648T3 (es) | 2012-01-05 |
| CN1875096A (zh) | 2006-12-06 |
| US8088620B2 (en) | 2012-01-03 |
| BRPI0415774A (pt) | 2006-12-26 |
| FR2862068A1 (fr) | 2005-05-13 |
| BRPI0415774B1 (pt) | 2019-12-31 |
| CN103952335B (zh) | 2016-08-31 |
| DK1680504T3 (da) | 2011-11-21 |
| AU2004289859B2 (en) | 2009-03-26 |
| FR2862068B1 (fr) | 2007-10-12 |
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