DK1680504T3 - Optimerede mikroorganisme-stammer for NADPH-forbrugende biosyntetiske pathways - Google Patents
Optimerede mikroorganisme-stammer for NADPH-forbrugende biosyntetiske pathwaysInfo
- Publication number
- DK1680504T3 DK1680504T3 DK04805397.9T DK04805397T DK1680504T3 DK 1680504 T3 DK1680504 T3 DK 1680504T3 DK 04805397 T DK04805397 T DK 04805397T DK 1680504 T3 DK1680504 T3 DK 1680504T3
- Authority
- DK
- Denmark
- Prior art keywords
- nadph
- biosynthetic pathways
- microorganism strains
- consuming
- optimized
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
- C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/12—Acting on D ring
- C12P33/16—Acting at 17 position
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0313056A FR2862068B1 (fr) | 2003-11-06 | 2003-11-06 | Souches de microorganismes optimisees pour des voies de biosyntheses consommatrices de nadph |
PCT/FR2004/002848 WO2005047498A1 (fr) | 2003-11-06 | 2004-11-05 | Souches de microorganismes optimisees pour des voies de biosynthese consommatrices de nadph |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1680504T3 true DK1680504T3 (da) | 2011-11-21 |
Family
ID=34508307
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04805397.9T DK1680504T3 (da) | 2003-11-06 | 2004-11-05 | Optimerede mikroorganisme-stammer for NADPH-forbrugende biosyntetiske pathways |
Country Status (16)
Country | Link |
---|---|
US (1) | US8088620B2 (da) |
EP (1) | EP1680504B1 (da) |
JP (1) | JP5553956B2 (da) |
KR (1) | KR101149566B1 (da) |
CN (2) | CN103952335B (da) |
AT (1) | ATE529504T1 (da) |
AU (1) | AU2004289859B2 (da) |
BR (1) | BRPI0415774B1 (da) |
CA (1) | CA2544507A1 (da) |
DK (1) | DK1680504T3 (da) |
ES (1) | ES2371648T3 (da) |
FR (1) | FR2862068B1 (da) |
IL (1) | IL174890A0 (da) |
RU (1) | RU2006119625A (da) |
WO (1) | WO2005047498A1 (da) |
ZA (1) | ZA200603590B (da) |
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RU2004124226A (ru) | 2004-08-10 | 2006-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Использование фосфокетолазы для продукции полезных метаболитов |
ES2341264T3 (es) * | 2004-08-10 | 2010-06-17 | Ajinomoto Co., Inc. | El uso de fosfocetolasa para producir metabolitos utiles. |
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US8673601B2 (en) * | 2007-01-22 | 2014-03-18 | Genomatica, Inc. | Methods and organisms for growth-coupled production of 3-hydroxypropionic acid |
EP2215243A2 (en) * | 2007-10-31 | 2010-08-11 | GEVO, Inc. | Methods for the economical production of biofuel precursor that is also a biofuel from biomass |
US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
US8691553B2 (en) | 2008-01-22 | 2014-04-08 | Genomatica, Inc. | Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol |
JP5755884B2 (ja) | 2008-03-05 | 2015-07-29 | ジェノマティカ, インコーポレイテッド | 第一級アルコールを産生する生物 |
US8241877B2 (en) | 2008-05-01 | 2012-08-14 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
WO2010022763A1 (en) * | 2008-08-25 | 2010-03-04 | Metabolic Explorer | Method for the preparation of 2-hydroxy-isobutyrate |
US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
CA2737112A1 (en) * | 2008-10-27 | 2010-06-03 | Butamax Advanced Biofuels Llc | Carbon pathway optimized production hosts for the production of isobutanol |
US20100143997A1 (en) | 2008-10-31 | 2010-06-10 | Thomas Buelter | Engineered microorganisms capable of producing target compounds under anaerobic conditions |
KR101827230B1 (ko) | 2008-12-31 | 2018-02-07 | 메타볼릭 익스플로러 | 디올의 제조 방법 |
BRPI1013505A2 (pt) | 2009-04-30 | 2018-02-14 | Genomatica Inc | organismos para a produção de isopropanol, n-butanol, e isobutanol |
CN106119113A (zh) | 2009-04-30 | 2016-11-16 | 基因组股份公司 | 用于生产 1,3‑丁二醇的生物 |
EP2462221B1 (en) | 2009-08-05 | 2017-02-22 | Genomatica, Inc. | Semi-synthetic terephthalic acid via microorganisms that produce muconic acid |
US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
BR112012006801A2 (pt) | 2009-09-27 | 2018-04-10 | Opx Biotechnologies Inc | método para produção de ácido 3-hidroxipropiônico e outros produtos |
US20110097767A1 (en) | 2009-10-23 | 2011-04-28 | Priti Pharkya | Microorganisms for the production of aniline |
JPWO2011052482A1 (ja) * | 2009-10-29 | 2013-03-21 | 三井化学株式会社 | イソプロピルアルコール生産細菌及びイソプロピルアルコール生産方法 |
WO2011063363A2 (en) * | 2009-11-20 | 2011-05-26 | Opx Biotechnologies, Inc. | Production of an organic acid and/or related chemicals |
MX2012008738A (es) | 2010-01-29 | 2012-08-31 | Genomatica Inc | Microorganismos y metodos para la biosintesis de p-toluato y tereftalato. |
CN103189513A (zh) * | 2010-03-31 | 2013-07-03 | 纳幕尔杜邦公司 | 上调磷酸戊糖途径以提高转基因微生物中受关注的非天然产物的产量 |
US9023636B2 (en) | 2010-04-30 | 2015-05-05 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of propylene |
EP2588598B1 (en) | 2010-07-02 | 2016-03-09 | Metabolic Explorer | Method for the preparation of hydroxy acids |
TWI500768B (zh) | 2010-07-05 | 2015-09-21 | Metabolic Explorer Sa | 由蔗糖製備1,3-丙二醇之方法 |
EP3312284A3 (en) | 2010-07-26 | 2018-05-30 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene |
AR083468A1 (es) * | 2010-10-25 | 2013-02-27 | Metabolic Explorer Sa | Aumento de la disponibilidad de nadph para la produccion de metionina |
KR20120108538A (ko) * | 2011-03-24 | 2012-10-05 | 삼성전자주식회사 | 말로닉 세미알데히드 환원 경로를 이용한 3-하이드록시프로피온산의 생산방법 |
US20120247066A1 (en) | 2011-04-01 | 2012-10-04 | Ice House America, Llc | Ice bagging apparatus and methods |
US9169486B2 (en) | 2011-06-22 | 2015-10-27 | Genomatica, Inc. | Microorganisms for producing butadiene and methods related thereto |
EP2540834A1 (en) | 2011-06-29 | 2013-01-02 | Metabolic Explorer | Method for the preparation of 1,3-propanediol |
US9822387B2 (en) | 2011-07-29 | 2017-11-21 | Mitsui Chemicals, Inc. | Microorganism having carbon dioxide fixation pathway introduced thereinto |
WO2013053824A1 (en) | 2011-10-11 | 2013-04-18 | Metabolic Explorer | New biosynthesis pathway for prenol in a recombinant microorganism |
EP2647718A3 (en) | 2012-04-06 | 2014-12-24 | Metabolic Explorer | Process for producing 5-aminopentanoate empolying a recombinant microorganism |
US9181568B2 (en) | 2012-04-23 | 2015-11-10 | Exxonmobil Research And Engineering Company | Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases |
SG11201501013PA (en) | 2012-08-10 | 2015-04-29 | Opx Biotechnologies Inc | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
WO2014049382A2 (en) | 2012-09-26 | 2014-04-03 | Metabolic Explorer | Ethylenediamine fermentative production by a recombinant microorganism |
WO2014062703A1 (en) * | 2012-10-15 | 2014-04-24 | Calysta Energy, Inc. | Genetically engineered microorganisms for biological oxidation of hydrocarbons |
KR101714943B1 (ko) | 2013-01-24 | 2017-03-09 | 미쓰이 가가쿠 가부시키가이샤 | 이산화탄소 고정 회로를 도입한 미생물 |
EP2976141A4 (en) | 2013-03-15 | 2016-10-05 | Cargill Inc | FLASHING FOR PRODUCTION CLEANING AND RECOVERY |
US20150119601A1 (en) | 2013-03-15 | 2015-04-30 | Opx Biotechnologies, Inc. | Monofunctional mcr + 3-hp dehydrogenase |
CN103205391A (zh) * | 2013-04-12 | 2013-07-17 | 浙江大学 | 一种基因工程菌及其应用 |
US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
BR112016001026A2 (pt) | 2013-07-19 | 2017-10-24 | Cargill Inc | organismo geneticamente modificado |
ES2704697T3 (es) | 2013-08-05 | 2019-03-19 | Greenlight Biosciences Inc | Proteínas genomodificadas con un sitio de escisión de proteasa |
CN103710396A (zh) * | 2013-12-30 | 2014-04-09 | 南京工业大学 | 一种提高厌氧发酵目标产物转化率的方法 |
BR112016026164B1 (pt) * | 2014-05-12 | 2023-10-31 | Metabolic Explorer | Novo microrganismo e método para a produção de 1,2-propanodiol com base em acetol redutase dependente de nadph e suprimento de nadph aprimorado |
EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
EP3050970B1 (en) | 2015-01-28 | 2019-09-18 | Metabolic Explorer | Modified microorganism for optimized production of 1,4-butanediol |
CN107771214B (zh) | 2015-04-07 | 2022-01-18 | 代谢探索者公司 | 用于具有增加的2,4-二羟基丁酸外排物的优化的2,4-二羟基丁酸产生的修饰的微生物 |
BR112017021255A2 (pt) | 2015-04-07 | 2018-06-26 | Metabolic Explorer Sa | microrganismo modificado para a produção otimizada de 2,4-di-hidroxibutirato |
WO2017042602A1 (en) | 2015-09-10 | 2017-03-16 | Metabolic Explorer | New lactaldehyde reductases for the production of 1,2-propanediol |
CN106086082B (zh) * | 2016-06-01 | 2019-11-15 | 苏州华赛生物工程技术有限公司 | 一种改良重组大肠杆菌生产9-癸烯醇的方法 |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
EP3342873A1 (en) | 2016-12-29 | 2018-07-04 | Metabolic Explorer | Conversion of methylglyoxal into hydroxyacetone using enzymes and applications thereof |
CN110494566A (zh) | 2017-02-02 | 2019-11-22 | 嘉吉公司 | 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞 |
EP3428282A1 (en) * | 2017-07-11 | 2019-01-16 | Alderys | Ectoine-producing yeast |
KR101894984B1 (ko) * | 2017-07-14 | 2018-09-05 | 한국과학기술원 | 환원력이 증가된 캔디다 속 변이 균주 및 이의 용도 |
CN115747240A (zh) * | 2022-08-05 | 2023-03-07 | 华熙生物科技股份有限公司 | 一种生产雌马酚的重组大肠杆菌工程菌株及应用 |
CN117487681A (zh) * | 2023-11-16 | 2024-02-02 | 湖南农业大学 | 一种生产角鲨烯的酵母工程菌及其应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9614618D0 (en) * | 1996-07-11 | 1996-09-04 | Animal Health Inst | Vaccine compositions |
JP4380029B2 (ja) * | 2000-07-05 | 2009-12-09 | 味の素株式会社 | 微生物を利用した物質の製造法 |
-
2003
- 2003-11-06 FR FR0313056A patent/FR2862068B1/fr not_active Expired - Fee Related
-
2004
- 2004-11-05 AU AU2004289859A patent/AU2004289859B2/en not_active Ceased
- 2004-11-05 EP EP04805397A patent/EP1680504B1/fr active Active
- 2004-11-05 AT AT04805397T patent/ATE529504T1/de not_active IP Right Cessation
- 2004-11-05 ES ES04805397T patent/ES2371648T3/es active Active
- 2004-11-05 CA CA002544507A patent/CA2544507A1/fr not_active Abandoned
- 2004-11-05 DK DK04805397.9T patent/DK1680504T3/da active
- 2004-11-05 JP JP2006537373A patent/JP5553956B2/ja not_active Expired - Fee Related
- 2004-11-05 CN CN201410119033.8A patent/CN103952335B/zh active Active
- 2004-11-05 WO PCT/FR2004/002848 patent/WO2005047498A1/fr active Application Filing
- 2004-11-05 CN CNA2004800319806A patent/CN1875096A/zh active Pending
- 2004-11-05 BR BRPI0415774A patent/BRPI0415774B1/pt active IP Right Grant
- 2004-11-05 KR KR1020067008922A patent/KR101149566B1/ko active IP Right Grant
- 2004-11-05 US US10/577,084 patent/US8088620B2/en not_active Expired - Fee Related
- 2004-11-05 RU RU2006119625/13A patent/RU2006119625A/ru not_active Application Discontinuation
-
2006
- 2006-04-10 IL IL174890A patent/IL174890A0/en unknown
- 2006-05-05 ZA ZA200603590A patent/ZA200603590B/en unknown
Also Published As
Publication number | Publication date |
---|---|
FR2862068A1 (fr) | 2005-05-13 |
EP1680504A1 (fr) | 2006-07-19 |
BRPI0415774B1 (pt) | 2019-12-31 |
ES2371648T3 (es) | 2012-01-05 |
US8088620B2 (en) | 2012-01-03 |
CN1875096A (zh) | 2006-12-06 |
ATE529504T1 (de) | 2011-11-15 |
AU2004289859A1 (en) | 2005-05-26 |
JP5553956B2 (ja) | 2014-07-23 |
US20070087403A1 (en) | 2007-04-19 |
IL174890A0 (en) | 2006-08-20 |
CA2544507A1 (fr) | 2005-05-26 |
WO2005047498A1 (fr) | 2005-05-26 |
KR20060132577A (ko) | 2006-12-21 |
BRPI0415774A (pt) | 2006-12-26 |
RU2006119625A (ru) | 2007-12-27 |
EP1680504B1 (fr) | 2011-10-19 |
FR2862068B1 (fr) | 2007-10-12 |
CN103952335B (zh) | 2016-08-31 |
KR101149566B1 (ko) | 2012-07-05 |
AU2004289859B2 (en) | 2009-03-26 |
JP2007510411A (ja) | 2007-04-26 |
CN103952335A (zh) | 2014-07-30 |
ZA200603590B (en) | 2007-07-25 |
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