ZA200507983B - Thorium-227 for use in radiotherapy of soft tissue disease - Google Patents
Thorium-227 for use in radiotherapy of soft tissue disease Download PDFInfo
- Publication number
- ZA200507983B ZA200507983B ZA200507983A ZA200507983A ZA200507983B ZA 200507983 B ZA200507983 B ZA 200507983B ZA 200507983 A ZA200507983 A ZA 200507983A ZA 200507983 A ZA200507983 A ZA 200507983A ZA 200507983 B ZA200507983 B ZA 200507983B
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- ZA
- South Africa
- Prior art keywords
- thorium
- soft tissue
- complexing agent
- complex
- radium
- Prior art date
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
- A61K51/1096—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies radioimmunotoxins, i.e. conjugates being structurally as defined in A61K51/1093, and including a radioactive nucleus for use in radiotherapeutic applications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
-
- A—HUMAN NECESSITIES
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- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
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- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Public Health (AREA)
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- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Radiation-Therapy Devices (AREA)
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Applications Claiming Priority (1)
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|---|---|---|---|
| GBGB0308731.9A GB0308731D0 (en) | 2003-04-15 | 2003-04-15 | Method of radiotherapy |
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|---|---|
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| KR (2) | KR101274867B1 (enExample) |
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| PL (1) | PL1617876T3 (enExample) |
| PT (1) | PT1617876E (enExample) |
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| CA2522148C (en) * | 2003-04-15 | 2010-07-13 | Algeta As | Thorium-227 for use in radiotherapy of soft tissue disease |
| GB201002508D0 (en) * | 2010-02-12 | 2010-03-31 | Algeta As | Product |
| GB201007354D0 (en) * | 2010-04-30 | 2010-06-16 | Algeta Asa | Method |
| GB201105298D0 (en) * | 2011-03-29 | 2011-05-11 | Algeta Asa | Pharmaceutical preparation |
| GB201600153D0 (en) * | 2016-01-05 | 2016-02-17 | Bayer As | Isotope preparation method |
| GB201600154D0 (en) * | 2016-01-05 | 2016-02-17 | Bayer As | Isotope preparation method |
| ES2952744T3 (es) | 2016-12-15 | 2023-11-03 | Nestle Sa | Composiciones y procedimientos que modulan los glóbulos blancos o los neutrófilos en un animal de compañía |
| FR3088769B1 (fr) * | 2018-11-15 | 2020-12-25 | Orano Med | Procede de preparation d'au moins un generateur a haute teneur en radium-228 |
| RU2767567C1 (ru) * | 2020-10-27 | 2022-03-17 | Станислав Анатольевич Дороватовский | Комплексные соединения, содержащие в своем составе радионуклид 227Th, а также бисфосфонатный фрагмент, способы их получения, а также потенциальное применение в качестве действующего вещества в составе остеотропного радиофармацевтического лекарственного препарата |
| CN119912489B (zh) * | 2024-12-23 | 2026-02-03 | 中国科学院近代物理研究所 | 一种膦酸钍框架材料及其制备方法和在钍镭发生器中的应用 |
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| CA2034484C (en) * | 1989-06-19 | 2000-08-15 | Maurits W. Geerlings | Radioimmunotherapy using .alpha.-particles emission |
| SG52470A1 (en) * | 1992-04-13 | 1998-09-28 | Dow Chemical Co | Process for preparing macrocyclic chelating agents and formation of chelates and conjugates thereof |
| CN1073860C (zh) * | 1998-08-20 | 2001-10-31 | 中国核动力研究设计院 | 用于骨肿瘤治疗或诊断的放射性药物药盒的制备方法 |
| MY133346A (en) * | 1999-03-01 | 2007-11-30 | Biogen Inc | Kit for radiolabeling ligands with yttrium-90 |
| NO314537B1 (no) | 1999-12-06 | 2003-04-07 | Anticancer Therapeutic Inv Sa | Reseptorbindende konjugater |
| NO312708B1 (no) * | 2000-02-21 | 2002-06-24 | Anticancer Therapeutic Inv Sa | Radioaktive liposomer til terapi |
| AU4906901A (en) * | 2000-02-25 | 2001-09-17 | Dangshe Ma | Actinium-225 complexes and conjugates for radioimmunotherapy |
| NO313180B1 (no) * | 2000-07-04 | 2002-08-26 | Anticancer Therapeutic Inv Sa | Bensökende alfapartikkel emitterende radiofarmasöytika |
| ITMI20022411A1 (it) * | 2002-11-14 | 2004-05-15 | Bracco Imaging Spa | Agenti per la diagnosi e la terapia di tumori che espongono sulla superficie delle cellule proteine alterate. |
| CA2522148C (en) * | 2003-04-15 | 2010-07-13 | Algeta As | Thorium-227 for use in radiotherapy of soft tissue disease |
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2004
- 2004-04-15 CA CA2522148A patent/CA2522148C/en not_active Expired - Lifetime
- 2004-04-15 DK DK04727587.0T patent/DK1617876T3/da active
- 2004-04-15 ZA ZA200507983A patent/ZA200507983B/en unknown
- 2004-04-15 JP JP2006506137A patent/JP5006032B2/ja not_active Expired - Lifetime
- 2004-04-15 AU AU2004229218A patent/AU2004229218B2/en not_active Expired
- 2004-04-15 KR KR1020117003862A patent/KR101274867B1/ko not_active Expired - Lifetime
- 2004-04-15 BR BRPI0409387A patent/BRPI0409387B8/pt not_active IP Right Cessation
- 2004-04-15 PL PL04727587T patent/PL1617876T3/pl unknown
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- 2004-04-15 ES ES04727587.0T patent/ES2486845T3/es not_active Expired - Lifetime
- 2004-04-15 PT PT47275870T patent/PT1617876E/pt unknown
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- 2004-04-15 NZ NZ543044A patent/NZ543044A/en not_active IP Right Cessation
- 2004-04-15 KR KR1020057019497A patent/KR20060015507A/ko not_active Ceased
- 2004-04-15 MX MXPA05010804A patent/MXPA05010804A/es active IP Right Grant
- 2004-04-15 EA EA200501456A patent/EA008195B1/ru not_active IP Right Cessation
- 2004-04-15 CN CN200480016329A patent/CN100586484C/zh not_active Expired - Lifetime
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2005
- 2005-09-28 IL IL171148A patent/IL171148A/en active IP Right Grant
- 2005-11-15 NO NO20055390A patent/NO332931B1/no unknown
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2011
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2014
- 2014-07-28 CY CY20141100569T patent/CY1115407T1/el unknown
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