ZA200500951B - Azabicyclo derivatives as muscarinic receptor antagonists - Google Patents
Azabicyclo derivatives as muscarinic receptor antagonistsInfo
- Publication number
- ZA200500951B ZA200500951B ZA200500951A ZA200500951A ZA200500951B ZA 200500951 B ZA200500951 B ZA 200500951B ZA 200500951 A ZA200500951 A ZA 200500951A ZA 200500951 A ZA200500951 A ZA 200500951A ZA 200500951 B ZA200500951 B ZA 200500951B
- Authority
- ZA
- South Africa
- Prior art keywords
- receptor antagonists
- muscarinic receptor
- derivatives
- azabicyclo
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2002/002663 WO2004004629A2 (en) | 2002-07-08 | 2002-07-08 | 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200500951B true ZA200500951B (en) | 2006-07-26 |
Family
ID=30011691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200500951A ZA200500951B (en) | 2002-07-08 | 2005-02-02 | Azabicyclo derivatives as muscarinic receptor antagonists |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7399779B2 (de) |
| EP (2) | EP1546099B1 (de) |
| JP (2) | JP2006502985A (de) |
| CN (2) | CN1668585A (de) |
| AT (2) | ATE419236T1 (de) |
| AU (2) | AU2002345266B2 (de) |
| BR (2) | BR0215801A (de) |
| CA (2) | CA2492121A1 (de) |
| CY (1) | CY1105879T1 (de) |
| DE (2) | DE60230683D1 (de) |
| DK (1) | DK1551803T3 (de) |
| EA (3) | EA200500173A1 (de) |
| ES (1) | ES2274275T3 (de) |
| HK (2) | HK1079783A1 (de) |
| MX (2) | MXPA05000434A (de) |
| NZ (2) | NZ537584A (de) |
| PT (1) | PT1551803E (de) |
| SI (1) | SI1551803T1 (de) |
| WO (2) | WO2004004629A2 (de) |
| ZA (1) | ZA200500951B (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1546099B1 (de) | 2002-07-08 | 2008-12-31 | Ranbaxy Laboratories Limited | 3,6-disubstituierte azabicyclo-3.1.0 hexan-derivate als muscarinische rezeptorantagonisten |
| JP2006518707A (ja) | 2002-12-10 | 2006-08-17 | ランバクシー ラボラトリーズ リミテッド | ムスカリン様受容体アンタゴニストとしての３，６−二置換アザビシクロ［３．１．０］ヘキサン誘導体 |
| EP1618091A1 (de) | 2003-04-09 | 2006-01-25 | Ranbaxy Laboratories, Ltd. | Substituierte azabicyclohexanderivate als antagonisten von muscarinrezeptoren |
| NZ542952A (en) * | 2003-04-11 | 2008-11-28 | Ranbaxy Lab Ltd | Azabicyclo derivatives as muscarinic receptor antagonists |
| AP2006003592A0 (en) * | 2003-10-14 | 2006-04-30 | Pfizer Prod Inc | Bicyclic [3.1.0] derivatives as glycine transporter inhibitors. |
| WO2005092341A1 (en) * | 2004-03-22 | 2005-10-06 | Ranbaxy Laboratories Limited | Combination therapy for lower urinary tract symptoms |
| ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
| WO2006003587A2 (en) * | 2004-07-01 | 2006-01-12 | Ranbaxy Laboratories Limited | Solid oral dosage forms of azabicyclo derivatives |
| WO2006016245A1 (en) * | 2004-08-05 | 2006-02-16 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| EP1794161A2 (de) * | 2004-09-24 | 2007-06-13 | Ranbaxy Laboratories Limited | Antagonisten des muskarinrezeptors |
| WO2006035282A2 (en) * | 2004-09-27 | 2006-04-06 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| EP1828174A1 (de) * | 2004-11-19 | 2007-09-05 | Ranbaxy Laboratories Limited | Azabicyclische antagonisten des muskarinrezeptors |
| US20100035954A1 (en) * | 2004-12-15 | 2010-02-11 | Mohammad Salman | Acid addition salts of muscarinic receptor antagonists |
| US20080319043A1 (en) * | 2005-05-03 | 2008-12-25 | Mohammad Salman | 3,6-Disubstituted Azabicyclo (3.1.0) Hexane Derivatives as Muscarinic Receptor Antagonists |
| WO2007039884A1 (en) | 2005-10-05 | 2007-04-12 | Ranbaxy Laboratories Limited | 3 -azabicyclooctane derivatives as muscarinic receptor antagonists |
| AU2006305619A1 (en) * | 2005-10-19 | 2007-04-26 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of muscarinic receptor antagonists |
| EP1968980A1 (de) | 2005-12-30 | 2008-09-17 | Ranbaxy Laboratories, Ltd. | Muscarin-rezeptor-antagonisten |
| CA2635335A1 (en) | 2005-12-30 | 2007-07-12 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| WO2008075321A2 (en) * | 2006-12-21 | 2008-06-26 | Ranbaxy Laboratories Limited | Modified-release formulations of azabicyclo derivatives |
| US20090326004A1 (en) | 2008-06-03 | 2009-12-31 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| EP2621902B1 (de) | 2010-09-28 | 2017-04-12 | Panacea Biotec Ltd | 3-azabicyclo[3.1.0]hexanverbindungen zur behandlung von zns-erkrankungen |
| WO2018136437A2 (en) * | 2017-01-17 | 2018-07-26 | Tesaro, Inc. | Compounds useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase |
| EP3823604A4 (de) | 2018-07-17 | 2022-03-16 | Board of Regents, The University of Texas System | Verbindungen als inhibitoren der indolamin-2,3-dioxygenase und/oder tryptophan-dioxygenase |
| CN111317754B (zh) * | 2018-12-13 | 2022-02-18 | 泰州医药城国科化物生物医药科技有限公司 | 一种北豆根总碱的制备方法及应用 |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2490714A (en) | 1947-05-13 | 1949-12-06 | Du Pont | Preparation of diazoacetic esters |
| NL124473C (de) | 1960-07-26 | |||
| SE8800207D0 (sv) | 1988-01-22 | 1988-01-22 | Kabivitrum Ab | Nya aminer, deras anvendning och framstellning |
| US5001160A (en) | 1988-04-28 | 1991-03-19 | Marion Laboratories, Inc. | 1-aryl-1-hydroxy-1-substituted-3-(4-substituted-1-piperazinyl)-2-propanones and their use in treatment of neurogenic bladder disorders |
| GB8906166D0 (en) | 1989-03-17 | 1989-05-04 | Pfizer Ltd | Therapeutic agents |
| US5164402A (en) | 1989-08-16 | 1992-11-17 | Pfizer Inc | Azabicyclo quinolone and naphthyridinone carboxylic acids |
| WO1991002526A1 (en) | 1989-08-16 | 1991-03-07 | Pfizer Inc. | Azabicyclo quinolone carboxylic acids |
| GB8928042D0 (en) | 1989-12-12 | 1990-02-14 | Pfizer Ltd | Muscarinic receptor antagonists |
| US5281601A (en) | 1989-12-12 | 1994-01-25 | Pfizer Inc. | Muscarinic receptor antagonists |
| FR2659323B1 (fr) | 1990-03-07 | 1992-06-12 | Synthelabo | Derives de 4-(aminomethyl) piperidine, leur preparation et leur application en therapeutique. |
| JPH0492921A (ja) | 1990-08-03 | 1992-03-25 | Fujitsu Ltd | 指数関数演算器 |
| GB9020051D0 (en) | 1990-09-13 | 1990-10-24 | Pfizer Ltd | Muscarinic receptor antagonists |
| GB9202443D0 (en) | 1992-02-05 | 1992-03-18 | Fujisawa Pharmaceutical Co | A novel substituted-acetamide compound and a process for the preparation thereof |
| FI100051B (fi) | 1992-02-18 | 1997-09-15 | Favorit Oy | Kompostori |
| JPH0635958A (ja) | 1992-07-14 | 1994-02-10 | Hitachi Ltd | 語句検索方法 |
| JP3429338B2 (ja) | 1992-07-27 | 2003-07-22 | 杏林製薬株式会社 | 新規なアリールグリシンアミド誘導体及びその製造法 |
| JPH06135958A (ja) | 1992-10-28 | 1994-05-17 | Tanabe Seiyaku Co Ltd | ベンゾシクロヘプテン誘導体及びその製法 |
| SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
| ATE152302T1 (de) | 1993-02-24 | 1997-05-15 | Siemens Ag | Sperrwandler-schaltnetzteil mit einem halbleiterschaltelement geringer spannungsfestigkeit |
| NO2005012I1 (no) | 1994-12-28 | 2005-06-06 | Debio Rech Pharma Sa | Triptorelin og farmasoytisk akseptable salter derav |
| WO1996033973A1 (fr) | 1995-04-28 | 1996-10-31 | Banyu Pharmaceutical Co., Ltd. | Derives disubstitues en position 1,4 de piperidine |
| CA2179574A1 (en) | 1995-06-26 | 1996-12-27 | Tomomi Okada | Substituted piperidine derivative and medicine comprising the same |
| US6130232A (en) | 1995-10-13 | 2000-10-10 | Banyu Pharmaceutical Coaltd | Substituted piperidine derivatives as muscarinic M3 receptor antagonists |
| AU2793197A (en) | 1996-05-31 | 1998-01-05 | Banyu Pharmaceutical Co., Ltd. | 1,4-disubstituted piperidine derivatives |
| EP0932401A1 (de) | 1996-07-01 | 1999-08-04 | Sepracor, Inc. | Methoden und zusammensetzungen zur behandlung von harninkontiniez mittels enantiomerishc angereichertem (r,r)-glycopyrrolat |
| WO1998000133A1 (en) | 1996-07-01 | 1998-01-08 | Sepracor, Inc. | Methods and compositions for treating urinary incontinence using enantiomerically enriched (s,s)-glycopyrrolate |
| EP0909163A4 (de) | 1996-07-01 | 1999-06-09 | Sepracor Inc | Verfahren und mittel zur behandlung der harninkontinenz unter hauptsaechlicher verwendung des (s,r)-glycopyrrolat enantiomers |
| EP0909172A4 (de) | 1996-07-01 | 1999-06-09 | Sepracor Inc | Verfahren und zusammensetzungen zur behandlung von harninkontinenz unter verwendung von enantiomer-angereichertem (r,s)-glycopyrrolat |
| PE92198A1 (es) | 1996-08-01 | 1999-01-09 | Banyu Pharma Co Ltd | Derivados de 1,4-piperidina disustituida que contienen fluor |
| KR20000057548A (ko) | 1996-12-13 | 2000-09-25 | 알프레드 엘. 미첼슨 | 광학적 전송물질 및 결합재 |
| JP2002512625A (ja) | 1997-05-29 | 2002-04-23 | メルク エンド カンパニー インコーポレーテッド | 細胞接着阻害薬としての複素環アミド化合物 |
| US6319920B1 (en) | 1998-02-27 | 2001-11-20 | Syntex (U.S.A.) Llc | 2-arylethyl-(piperidin-4-ylmethyl)amine derivatives |
| TWI244481B (en) | 1998-12-23 | 2005-12-01 | Pfizer | 3-azabicyclo[3.1.0]hexane derivatives useful in therapy |
| UA73543C2 (uk) | 1999-12-07 | 2005-08-15 | Тераванс, Інк. | Похідні сечовини, фармацевтична композиція та застосування похідного при приготуванні лікарського засобу для лікування захворювання, яке опосередковується мускариновим рецептором |
| WO2001042212A1 (en) | 1999-12-07 | 2001-06-14 | Theravance, Inc. | Carbamate derivatives having muscarinic receptor antagonist activity |
| SE9904765D0 (sv) | 1999-12-23 | 1999-12-23 | Astra Ab | Pharmaceutically-useful compounds |
| DE60114413T2 (de) | 2000-05-25 | 2006-07-27 | F. Hoffmann-La Roche Ag | Substituierte 1-aminoalkyl-lactame und deren verwendung als muscarinrezeptor-antagonisten |
| YU89002A (sh) | 2000-05-25 | 2006-01-16 | F. Hoffmann-La Roche Ag. | Supstituisani 1-aminoalkil-laktami i njihova primena kao antagonista za muskarinske receptore |
| WO2002006241A1 (en) | 2000-06-14 | 2002-01-24 | Muscagen Limited | 1, 2, 3, 5 -tetrahydrobenzo`c!azepin-4-one derivatives having muscarinic antagonist activity |
| ES2213703T5 (es) | 2000-06-27 | 2011-11-02 | Laboratorios S.A.L.V.A.T., S.A. | Carbamatos derivados de arilalquilaminas. |
| CA2415468A1 (en) | 2000-07-11 | 2003-01-10 | Yoshio Ogino | Ester derivatives |
| EP1345937B1 (de) | 2000-12-22 | 2005-09-28 | Almirall Prodesfarma AG | Chinuclidincarbamat derivate und deren verwendung als m3 antagonisten |
| ES2266291T3 (es) | 2000-12-28 | 2007-03-01 | Almirall Prodesfarma Ag | Nuevos derivados de quinuclidina y composiciones medicinales que los contienen. |
| AU2002314744A1 (en) | 2001-04-17 | 2002-10-28 | Sepracor, Inc. | Thiazole and other heterocyclic ligands and use thereof |
| US7361668B2 (en) | 2001-10-17 | 2008-04-22 | Ucb, S.A. | Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors |
| KR100687992B1 (ko) | 2001-12-03 | 2007-02-27 | 에프. 호프만-라 로슈 아게 | 무스카린 수용체 길항제로서 4-피페리딘일 알킬아민 유도체 |
| JP4322675B2 (ja) | 2001-12-03 | 2009-09-02 | エフ．ホフマン−ラ ロシュ アーゲー | ムスカリン受容体アンタゴニストとしてのアミノテトラリン誘導体 |
| EP1546099B1 (de) | 2002-07-08 | 2008-12-31 | Ranbaxy Laboratories Limited | 3,6-disubstituierte azabicyclo-3.1.0 hexan-derivate als muscarinische rezeptorantagonisten |
| DE60226906D1 (de) | 2002-07-31 | 2008-07-10 | Ranbaxy Lab Ltd | 3,6-disubstituierte azabicyclo ä3.1.0ühexanderivate, die sich als muscarinrezeptorantagonisten eignen |
| AU2002321711A1 (en) | 2002-08-09 | 2004-02-25 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives useful as muscarinic receptor antagonist |
| EP1534675B1 (de) | 2002-08-23 | 2009-02-25 | Ranbaxy Laboratories, Ltd. | Fluor- und sulfonylaminohaltige, 3,6-disubstituierte azabicyclo¬3.1.0 hexanderivate als muscarinrezeptorantagonisten |
| JP2006518707A (ja) | 2002-12-10 | 2006-08-17 | ランバクシー ラボラトリーズ リミテッド | ムスカリン様受容体アンタゴニストとしての３，６−二置換アザビシクロ［３．１．０］ヘキサン誘導体 |
| AU2002356369A1 (en) | 2002-12-23 | 2004-07-14 | Ranbaxy Laboratories Limited | Xanthine derivatives as muscarinic receptor antagonists |
| AU2002347552A1 (en) | 2002-12-23 | 2004-07-14 | Ranbaxy Laboratories Limited | 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists |
| EP1581522B1 (de) | 2002-12-23 | 2008-02-20 | Ranbaxy Laboratories Limited | Flavaxat-derivate als muscarin-rezeptor antagonisten |
| US7488748B2 (en) | 2003-01-28 | 2009-02-10 | Ranbaxy Laboratories Limited | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| AU2003205964A1 (en) | 2003-02-07 | 2004-08-30 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| EP1618091A1 (de) | 2003-04-09 | 2006-01-25 | Ranbaxy Laboratories, Ltd. | Substituierte azabicyclohexanderivate als antagonisten von muscarinrezeptoren |
| US7592359B2 (en) | 2003-04-10 | 2009-09-22 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| US7560479B2 (en) | 2003-04-10 | 2009-07-14 | Ranbaxy Laboratories Limited | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| NZ542952A (en) | 2003-04-11 | 2008-11-28 | Ranbaxy Lab Ltd | Azabicyclo derivatives as muscarinic receptor antagonists |
| FR2855805B1 (fr) | 2003-06-06 | 2005-08-05 | Vallourec Vitry | Element de structure pour vehicule, capable d'un meilleur comportement aux chocs |
| WO2005092341A1 (en) | 2004-03-22 | 2005-10-06 | Ranbaxy Laboratories Limited | Combination therapy for lower urinary tract symptoms |
| WO2006035282A2 (en) | 2004-09-27 | 2006-04-06 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| US20100035954A1 (en) | 2004-12-15 | 2010-02-11 | Mohammad Salman | Acid addition salts of muscarinic receptor antagonists |
-
2002
- 2002-07-08 EP EP02743489A patent/EP1546099B1/de not_active Expired - Lifetime
- 2002-07-08 EA EA200500173A patent/EA200500173A1/ru unknown
- 2002-07-08 MX MXPA05000434A patent/MXPA05000434A/es unknown
- 2002-07-08 US US10/520,573 patent/US7399779B2/en not_active Expired - Fee Related
- 2002-07-08 AU AU2002345266A patent/AU2002345266B2/en not_active Expired - Fee Related
- 2002-07-08 CA CA002492121A patent/CA2492121A1/en not_active Abandoned
- 2002-07-08 AT AT02743489T patent/ATE419236T1/de not_active IP Right Cessation
- 2002-07-08 DE DE60230683T patent/DE60230683D1/de not_active Expired - Fee Related
- 2002-07-08 WO PCT/IB2002/002663 patent/WO2004004629A2/en active Application Filing
- 2002-07-08 JP JP2004519029A patent/JP2006502985A/ja active Pending
- 2002-07-08 CN CNA028295528A patent/CN1668585A/zh active Pending
- 2002-07-08 NZ NZ537584A patent/NZ537584A/en unknown
- 2002-07-08 BR BR0215801-9A patent/BR0215801A/pt not_active IP Right Cessation
-
2003
- 2003-04-11 EA EA200500172A patent/EA007932B1/ru not_active IP Right Cessation
- 2003-04-11 BR BR0312572-6A patent/BR0312572A/pt not_active IP Right Cessation
- 2003-04-11 NZ NZ537585A patent/NZ537585A/en unknown
- 2003-04-11 PT PT03762827T patent/PT1551803E/pt unknown
- 2003-04-11 WO PCT/IB2003/001367 patent/WO2004005252A1/en active IP Right Grant
- 2003-04-11 US US10/520,572 patent/US7544708B2/en not_active Expired - Fee Related
- 2003-04-11 JP JP2004519035A patent/JP2005535655A/ja active Pending
- 2003-04-11 EP EP03762827A patent/EP1551803B8/de not_active Expired - Lifetime
- 2003-04-11 AT AT03762827T patent/ATE342253T1/de not_active IP Right Cessation
- 2003-04-11 CA CA002491998A patent/CA2491998A1/en not_active Abandoned
- 2003-04-11 CN CNB038211300A patent/CN100519526C/zh not_active Expired - Fee Related
- 2003-04-11 SI SI200330515T patent/SI1551803T1/sl unknown
- 2003-04-11 DE DE60309057T patent/DE60309057T2/de not_active Expired - Fee Related
- 2003-04-11 MX MXPA05000435A patent/MXPA05000435A/es active IP Right Grant
- 2003-04-11 ES ES03762827T patent/ES2274275T3/es not_active Expired - Lifetime
- 2003-04-11 DK DK03762827T patent/DK1551803T3/da active
- 2003-04-11 AU AU2003226579A patent/AU2003226579B2/en not_active Ceased
-
2004
- 2004-01-07 EA EA200501595A patent/EA009942B1/ru not_active IP Right Cessation
-
2005
- 2005-02-02 ZA ZA200500951A patent/ZA200500951B/xx unknown
- 2005-12-28 HK HK05112034.8A patent/HK1079783A1/xx not_active IP Right Cessation
-
2006
- 2006-01-13 HK HK06100635A patent/HK1082728A1/xx not_active IP Right Cessation
- 2006-12-21 CY CY20061101846T patent/CY1105879T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA200500951B (en) | Azabicyclo derivatives as muscarinic receptor antagonists | |
| DE60231341D1 (de) | Fluor- und sulfonylaminohaltige, 3,6-disubstituierptorantagonisten | |
| HK1079787A1 (zh) | 用作毒蕈碱受體拮抗劑的3，6-二取代的氮雜雙環[3．1．0]己烷衍生物 | |
| HK1085724A1 (en) | 3,6-disubstituted azabicyclo 3.1.0-hexane derivatives as muscarinic receptor antagonists | |
| WO2005013894A3 (en) | Benzodiazepine cgrp receptor antagonists | |
| MY161834A (en) | Substituted diazepan compounds as orexin receptor antagonists | |
| WO2004091514A3 (en) | Cgrp receptor antagonists | |
| WO2005000807A3 (en) | Benzodiazepine cgrp receptor antagonists | |
| WO2006035282A3 (en) | Muscarinic receptor antagonists | |
| WO2006041830A3 (en) | Cgrp receptor antagonists | |
| WO2006044449A3 (en) | Cgrp receptor antagonists | |
| WO2006054162A8 (en) | Azabicyclic muscarinic receptor antagonists | |
| EA200501593A1 (ru) | Азабициклические производные в качестве антагонистов мускаринового рецептора | |
| WO2006018708A3 (en) | Pyrrolidine derivatives as muscarinic receptor antagonists | |
| WO2004067510A8 (en) | 3,6-disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists | |
| AU2002347553A1 (en) | Flavaxate derivatives as muscarinic receptor antagonists | |
| AU2003214535A8 (en) | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists | |
| WO2006032994A3 (en) | Muscarinic receptor antagonists | |
| WO2007007281A3 (en) | Muscarinic receptor antagonists | |
| DE602004018844D1 (de) | Als antagonisten des muscarinrezeptors geeignete xanthinderivate |