ZA200405635B - Ambroxol for treating painfull conditions in the mouth and pharyngeal cavity. - Google Patents
Ambroxol for treating painfull conditions in the mouth and pharyngeal cavity. Download PDFInfo
- Publication number
- ZA200405635B ZA200405635B ZA200405635A ZA200405635A ZA200405635B ZA 200405635 B ZA200405635 B ZA 200405635B ZA 200405635 A ZA200405635 A ZA 200405635A ZA 200405635 A ZA200405635 A ZA 200405635A ZA 200405635 B ZA200405635 B ZA 200405635B
- Authority
- ZA
- South Africa
- Prior art keywords
- oral
- pharmaceutical composition
- ambroxol
- pain
- pharyngeal
- Prior art date
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- JBDGDEWWOUBZPM-XYPYZODXSA-N ambroxol Chemical compound NC1=C(Br)C=C(Br)C=C1CN[C@@H]1CC[C@@H](O)CC1 JBDGDEWWOUBZPM-XYPYZODXSA-N 0.000 title claims description 35
- 229960005174 ambroxol Drugs 0.000 title claims description 34
- 238000011282 treatment Methods 0.000 claims description 30
- 239000008194 pharmaceutical composition Substances 0.000 claims description 28
- QNVKOSLOVOTXKF-UHFFFAOYSA-N 4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;hydron;chloride Chemical compound Cl.NC1=C(Br)C=C(Br)C=C1CNC1CCC(O)CC1 QNVKOSLOVOTXKF-UHFFFAOYSA-N 0.000 claims description 21
- 201000007100 Pharyngitis Diseases 0.000 claims description 21
- 229960000985 ambroxol hydrochloride Drugs 0.000 claims description 21
- 230000000694 effects Effects 0.000 claims description 13
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- 150000003839 salts Chemical class 0.000 claims description 10
- 208000009889 Herpes Simplex Diseases 0.000 claims description 9
- 208000002399 aphthous stomatitis Diseases 0.000 claims description 9
- 208000007565 gingivitis Diseases 0.000 claims description 9
- 230000003902 lesion Effects 0.000 claims description 9
- 210000004400 mucous membrane Anatomy 0.000 claims description 9
- 239000000796 flavoring agent Substances 0.000 claims description 6
- 239000011159 matrix material Substances 0.000 claims description 5
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- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 claims description 4
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- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 239000001685 glycyrrhizic acid Substances 0.000 description 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 229960004716 idoxuridine Drugs 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229960000274 lysozyme Drugs 0.000 description 1
- 235000010335 lysozyme Nutrition 0.000 description 1
- 239000004325 lysozyme Substances 0.000 description 1
- 229960003511 macrogol Drugs 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 230000000510 mucolytic effect Effects 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 229960000988 nystatin Drugs 0.000 description 1
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- RARSHUDCJQSEFJ-UHFFFAOYSA-N p-Hydroxypropiophenone Chemical compound CCC(=O)C1=CC=C(O)C=C1 RARSHUDCJQSEFJ-UHFFFAOYSA-N 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 229940068917 polyethylene glycols Drugs 0.000 description 1
- 229960002800 prednisolone acetate Drugs 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 239000010670 sage oil Substances 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 235000021092 sugar substitutes Nutrition 0.000 description 1
- 239000001117 sulphuric acid Substances 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000010678 thyme oil Substances 0.000 description 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
- 229940126307 triamcinolone acetate Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Nutrition Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Otolaryngology (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Physiology (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10208313A DE10208313A1 (de) | 2002-02-27 | 2002-02-27 | Ambroxol für die Behandlung von schmerzhaften Zuständen im Mund und Rachenraum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200405635B true ZA200405635B (en) | 2005-05-31 |
Family
ID=27740434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200405635A ZA200405635B (en) | 2002-02-27 | 2004-07-15 | Ambroxol for treating painfull conditions in the mouth and pharyngeal cavity. |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1480626A1 (de) |
| JP (1) | JP2005518435A (de) |
| KR (1) | KR20040084944A (de) |
| CN (1) | CN1638749A (de) |
| AR (1) | AR038698A1 (de) |
| AU (1) | AU2003210345B2 (de) |
| BR (1) | BR0308038A (de) |
| CA (1) | CA2477105A1 (de) |
| DE (1) | DE10208313A1 (de) |
| EC (1) | ECSP045242A (de) |
| IS (1) | IS7417A (de) |
| MX (1) | MXPA04008220A (de) |
| MY (1) | MY144781A (de) |
| PE (1) | PE20030830A1 (de) |
| PL (1) | PL371584A1 (de) |
| RU (1) | RU2311176C2 (de) |
| TW (1) | TW200306804A (de) |
| UA (1) | UA86741C2 (de) |
| UY (1) | UY27679A1 (de) |
| WO (1) | WO2003072094A1 (de) |
| ZA (1) | ZA200405635B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10332486A1 (de) * | 2003-07-16 | 2005-02-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol für die Behandlung akuter Schmerzen |
| JP2005120063A (ja) * | 2003-10-14 | 2005-05-12 | Boehringer Ingelheim Pharma Gmbh & Co Kg | 咽頭における炎症の治療のためのアンブロキソール |
| ITMI20032462A1 (it) * | 2003-12-16 | 2005-06-17 | Advance Holdings Ltd | Metodo per preparare una caramella contenente ambroxolo e la caramella cosi' ottenuta |
| DE102004021992A1 (de) * | 2004-05-03 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Topische Zubereitung enthaltend Ambroxol |
| JP2007084471A (ja) * | 2005-09-21 | 2007-04-05 | Sunstar Inc | 口腔用組成物および口腔用製品の選択方法 |
| EP2015761A4 (de) * | 2006-03-29 | 2009-07-29 | Naveh Pharma 1996 Ltd | Verfahren und zusammensetzung zur behandlung von halsentzündung |
| JP5765934B2 (ja) * | 2009-12-28 | 2015-08-19 | サンスター株式会社 | 口腔用組成物 |
| JP6171683B2 (ja) * | 2012-08-03 | 2017-08-02 | 大正製薬株式会社 | 固形製剤 |
| CN105769908B (zh) * | 2016-05-06 | 2019-03-01 | 湖北凤凰白云山药业有限公司 | 一种化痰止咳的药物及其制备方法 |
| AU2017357755B2 (en) | 2016-11-14 | 2019-06-13 | Neuvision Development Llc | Formulations for the treatment of ocular surface diseases and related methods |
| CN106727621A (zh) * | 2016-11-22 | 2017-05-31 | 郑州仁宏医药科技有限公司 | 一种治疗牙痛的西药散剂 |
| JP6844394B2 (ja) * | 2017-04-14 | 2021-03-17 | 大正製薬株式会社 | 固形組成物 |
| EP3415143A1 (de) * | 2017-06-16 | 2018-12-19 | Kai-Uwe Kern | Bromhexin zur behandlung von schmerz |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3432411A1 (de) * | 1983-09-17 | 1985-04-11 | Dr. Karl Thomae Gmbh, 7950 Biberach | Antiadhaesive prohylactica und arzneimittel, enthaltend ein sekretolytisch wirksames benzylaminderivat |
| DE3445226A1 (de) * | 1983-12-14 | 1985-08-01 | Reifenrath, Rainer Richard Otto, Dr.med., 7920 Heidenheim | Pharmazeutisches erzeugnis zur behandlung und prophylaxe von infektionen sowie von husten und obstruktiven atemwegserkrankungen |
| US5122540A (en) * | 1986-02-28 | 1992-06-16 | W. Keith R. Watson | Method and composition for treating warts and throat soreness with DMSO and citric acid |
| DE4415553A1 (de) * | 1994-05-03 | 1995-11-09 | Behringwerke Ag | Verwendung von Deoxyspergualin zur Herstellung eines Arzneimittels zur Behandlung von entzündlich-hyperreaktiven Erkrankungen |
| CA2253260A1 (en) * | 1996-05-02 | 1997-11-13 | Taisho Pharmaceutical Co., Ltd. | Suspension of sparingly water-soluble acidic drug |
| DE19933148A1 (de) * | 1999-07-20 | 2001-01-25 | Boehringer Ingelheim Int | Ambroxolhaltige Lutschtablette |
| JP2001151677A (ja) * | 1999-11-26 | 2001-06-05 | Taisho Pharmaceut Co Ltd | 咽頭用組成物 |
| DE20102817U1 (de) * | 2000-02-23 | 2001-06-07 | Bolder Arzneimittel Gmbh | Lutsch- und Kaupastillen mit Cyclodextrin |
| US6391886B1 (en) * | 2000-12-04 | 2002-05-21 | The Procter & Gamble Company | Oral compositions having improved consumer aesthetics |
-
2002
- 2002-02-27 DE DE10208313A patent/DE10208313A1/de not_active Withdrawn
-
2003
- 2003-02-25 AU AU2003210345A patent/AU2003210345B2/en not_active Ceased
- 2003-02-25 WO PCT/EP2003/001886 patent/WO2003072094A1/de active Application Filing
- 2003-02-25 CA CA002477105A patent/CA2477105A1/en not_active Abandoned
- 2003-02-25 UA UA20040907789A patent/UA86741C2/ru unknown
- 2003-02-25 KR KR10-2004-7013393A patent/KR20040084944A/ko active Search and Examination
- 2003-02-25 PL PL03371584A patent/PL371584A1/xx not_active Application Discontinuation
- 2003-02-25 MY MYPI20030651A patent/MY144781A/en unknown
- 2003-02-25 TW TW092103899A patent/TW200306804A/zh unknown
- 2003-02-25 JP JP2003570840A patent/JP2005518435A/ja active Pending
- 2003-02-25 BR BR0308038-2A patent/BR0308038A/pt not_active Expired - Fee Related
- 2003-02-25 UY UY27679A patent/UY27679A1/es not_active Application Discontinuation
- 2003-02-25 MX MXPA04008220A patent/MXPA04008220A/es not_active Application Discontinuation
- 2003-02-25 EP EP03742955A patent/EP1480626A1/de not_active Ceased
- 2003-02-25 RU RU2004129284/15A patent/RU2311176C2/ru not_active IP Right Cessation
- 2003-02-25 CN CNA038047683A patent/CN1638749A/zh active Pending
- 2003-02-26 AR ARP030100619A patent/AR038698A1/es not_active Suspension/Interruption
- 2003-02-26 PE PE2003000187A patent/PE20030830A1/es not_active Application Discontinuation
-
2004
- 2004-07-15 ZA ZA200405635A patent/ZA200405635B/en unknown
- 2004-08-19 IS IS7417A patent/IS7417A/is unknown
- 2004-08-20 EC EC2004005242A patent/ECSP045242A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE10208313A1 (de) | 2003-09-11 |
| WO2003072094A1 (de) | 2003-09-04 |
| KR20040084944A (ko) | 2004-10-06 |
| BR0308038A (pt) | 2004-12-28 |
| JP2005518435A (ja) | 2005-06-23 |
| MXPA04008220A (es) | 2004-11-26 |
| CN1638749A (zh) | 2005-07-13 |
| TW200306804A (en) | 2003-12-01 |
| IS7417A (is) | 2004-08-19 |
| CA2477105A1 (en) | 2003-09-04 |
| AU2003210345B2 (en) | 2009-01-29 |
| AU2003210345A1 (en) | 2003-09-09 |
| UY27679A1 (es) | 2003-09-30 |
| AR038698A1 (es) | 2005-01-26 |
| PE20030830A1 (es) | 2003-10-31 |
| UA86741C2 (ru) | 2009-05-25 |
| ECSP045242A (es) | 2004-09-28 |
| RU2311176C2 (ru) | 2007-11-27 |
| EP1480626A1 (de) | 2004-12-01 |
| MY144781A (en) | 2011-11-15 |
| PL371584A1 (en) | 2005-06-27 |
| RU2004129284A (ru) | 2005-06-10 |
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