ZA200402173B - Treatment of insulin resistance syndrome and type 2 diabetes with PDE9 inhibitors. - Google Patents
Treatment of insulin resistance syndrome and type 2 diabetes with PDE9 inhibitors. Download PDFInfo
- Publication number
- ZA200402173B ZA200402173B ZA200402173A ZA200402173A ZA200402173B ZA 200402173 B ZA200402173 B ZA 200402173B ZA 200402173 A ZA200402173 A ZA 200402173A ZA 200402173 A ZA200402173 A ZA 200402173A ZA 200402173 B ZA200402173 B ZA 200402173B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- inhibitor
- optionally substituted
- halo
- phenyl
- Prior art date
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- 208000001072 type 2 diabetes mellitus Diseases 0.000 title claims description 28
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- 238000011282 treatment Methods 0.000 title description 18
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| RU2019144010A (ru) | 2017-06-08 | 2021-07-13 | Мерк Шарп И Доум Корп. | Пиразолопиримидиновые ингибиторы pde9 |
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| AU2019223955B2 (en) | 2018-02-20 | 2024-06-13 | Incyte Corporation | N-(phenyl)-2-(phenyl)pyrimidine-4-carboxamide derivatives and related compounds as HPK1 inhibitors for treating cancer |
| US10752635B2 (en) | 2018-02-20 | 2020-08-25 | Incyte Corporation | Indazole compounds and uses thereof |
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| US4666908A (en) * | 1985-04-05 | 1987-05-19 | Warner-Lambert Company | 5-Substituted pyrazolo[4,3-d]pyrimidine-7-ones and methods of use |
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| GB9722520D0 (en) * | 1997-10-24 | 1997-12-24 | Pfizer Ltd | Compounds |
| US6444816B1 (en) * | 1997-10-27 | 2002-09-03 | Dr. Reddy's Research Foundation | Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof |
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| KR20040053210A (ko) * | 2001-11-02 | 2004-06-23 | 화이자 프로덕츠 인크. | Pde9 억제제를 사용한 인슐린 저항 증후군 및 2형당뇨병의 치료 |
| US20040220186A1 (en) * | 2003-04-30 | 2004-11-04 | Pfizer Inc. | PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease |
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| IL161155A0 (en) | 2004-08-31 |
| US20040023989A1 (en) | 2004-02-05 |
| JP2005508978A (ja) | 2005-04-07 |
| MXPA04004170A (es) | 2004-09-06 |
| US6967204B2 (en) | 2005-11-22 |
| PL370599A1 (en) | 2005-05-30 |
| HUP0401998A2 (hu) | 2005-01-28 |
| CA2465632A1 (en) | 2003-05-08 |
| KR20040053210A (ko) | 2004-06-23 |
| EP1444009A1 (en) | 2004-08-11 |
| CN1575191A (zh) | 2005-02-02 |
| US20050070557A1 (en) | 2005-03-31 |
| WO2003037432A1 (en) | 2003-05-08 |
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