ZA200401847B - Method of treating middle ear infections - Google Patents
Method of treating middle ear infections Download PDFInfo
- Publication number
- ZA200401847B ZA200401847B ZA2004/01847A ZA200401847A ZA200401847B ZA 200401847 B ZA200401847 B ZA 200401847B ZA 2004/01847 A ZA2004/01847 A ZA 2004/01847A ZA 200401847 A ZA200401847 A ZA 200401847A ZA 200401847 B ZA200401847 B ZA 200401847B
- Authority
- ZA
- South Africa
- Prior art keywords
- ciprodex
- ciprofloxacin
- dexamethasone
- ear
- patients
- Prior art date
Links
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- 206010033078 Otitis media Diseases 0.000 title claims abstract description 11
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- 229940035274 tobradex Drugs 0.000 description 1
- 229960000707 tobramycin Drugs 0.000 description 1
- 150000004684 trihydrates Chemical class 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
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Classifications
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US32395101P | 2001-09-21 | 2001-09-21 | |
| PCT/US2002/029373 WO2003026671A1 (en) | 2001-09-21 | 2002-09-13 | Method of treating middle ear infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200401847B true ZA200401847B (en) | 2005-05-25 |
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| ZA2004/01847A ZA200401847B (en) | 2001-09-21 | 2004-03-05 | Method of treating middle ear infections |
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| EP (1) | EP1429780B1 (enExample) |
| JP (1) | JP2005504804A (enExample) |
| KR (1) | KR20040035760A (enExample) |
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| AT (1) | ATE313328T1 (enExample) |
| AU (1) | AU2002333671B2 (enExample) |
| BR (1) | BR0212898A (enExample) |
| CA (1) | CA2459930C (enExample) |
| CY (1) | CY1104988T1 (enExample) |
| DE (1) | DE60208216T2 (enExample) |
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| ES (1) | ES2250739T3 (enExample) |
| FR (1) | FR13C0012I2 (enExample) |
| MX (1) | MXPA04002576A (enExample) |
| PL (1) | PL212457B1 (enExample) |
| RU (1) | RU2295346C2 (enExample) |
| WO (1) | WO2003026671A1 (enExample) |
| ZA (1) | ZA200401847B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030139382A1 (en) * | 2001-09-21 | 2003-07-24 | Alcon, Inc. | Method of treating middle ear infections |
| US7220431B2 (en) * | 2002-11-27 | 2007-05-22 | Regents Of The University Of Minnesota | Methods and compositions for applying pharmacologic agents to the ear |
| CA2576589C (en) * | 2004-08-13 | 2013-11-12 | Schering-Plough Ltd. | Pharmaceutical formulation comprising an antibiotic, a triazole and a corticosteroid |
| DE102005055385A1 (de) * | 2004-12-09 | 2006-06-14 | Bayer Healthcare Ag | Arzneimittel zur hygienischen Applikation im Ohr |
| US20070110788A1 (en) * | 2005-11-14 | 2007-05-17 | Hissong James B | Injectable formulation capable of forming a drug-releasing device |
| US7976873B2 (en) | 2006-05-10 | 2011-07-12 | Medtronic Xomed, Inc. | Extracellular polysaccharide solvating system for treatment of bacterial ear conditions |
| US7993675B2 (en) * | 2006-05-10 | 2011-08-09 | Medtronic Xomed, Inc. | Solvating system and sealant for medical use in the sinuses and nasal passages |
| US20070264296A1 (en) * | 2006-05-10 | 2007-11-15 | Myntti Matthew F | Biofilm extracellular polysachharide solvating system |
| US7959943B2 (en) * | 2006-05-10 | 2011-06-14 | Medtronics Xomed, Inc. | Solvating system and sealant for medical use in the middle or inner ear |
| US20080139545A1 (en) * | 2006-05-22 | 2008-06-12 | Won-Taek Choe | Formulation to treat ear infection |
| WO2008085913A1 (en) * | 2007-01-04 | 2008-07-17 | Rib-X Pharmaceuticals, Inc. | Methods for treating, preventing, or reducing the risk of opthalmic, otic, and nasal infections |
| US8088095B2 (en) | 2007-02-08 | 2012-01-03 | Medtronic Xomed, Inc. | Polymeric sealant for medical use |
| US20090263345A1 (en) * | 2008-01-28 | 2009-10-22 | Foresight Biotherapeutics, Inc. | Otic compositions for the treatment of infections of the internal and external ear in mammals |
| MY161021A (en) | 2008-05-14 | 2017-03-31 | Otonomy Inc | Controlled release corticosteroid and methods for the treatment of otic disorders |
| WO2009152374A2 (en) | 2008-06-12 | 2009-12-17 | Medtronic Xomed, Inc. | Method for treating chronic wounds |
| US20100016450A1 (en) * | 2008-07-21 | 2010-01-21 | Otonomy, Inc. | Controlled release delivery devices for the treatment of otic disorders |
| MX2011000862A (es) * | 2008-07-21 | 2011-03-15 | Otonomy Inc | Composiciones antimicrobianas de liberacion controlada y metodos para el tratamiento de trastornos oticos. |
| US8318817B2 (en) | 2008-07-21 | 2012-11-27 | Otonomy, Inc. | Controlled release antimicrobial compositions and methods for the treatment of otic disorders |
| EP2346324A4 (en) | 2008-10-06 | 2012-10-10 | Microbial Defense Systems Llc | ANTIMICROBIAL COMPOSITION AND METHODS OF MAKING AND USING |
| TW201023912A (en) * | 2008-12-05 | 2010-07-01 | Alcon Res Ltd | Pharmaceutical suspension |
| CN105362221A (zh) * | 2009-03-03 | 2016-03-02 | 爱尔康研究有限公司 | 向眼部递送受体酪氨酸激酶抑制性(RTKi)化合物的药物组合物 |
| US8912236B2 (en) * | 2009-03-03 | 2014-12-16 | Alcon Research, Ltd. | Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (RTKi) compounds to the eye |
| WO2010143186A1 (en) * | 2009-06-08 | 2010-12-16 | Otic Pharma Ltd. | Otic foam formulations |
| WO2011049958A2 (en) * | 2009-10-21 | 2011-04-28 | Otonomy, Inc. | Modulation of gel temperature of poloxamer-containing formulations |
| EP3456200B1 (en) | 2011-05-10 | 2023-05-03 | Next Science IP Holdings Pty Ltd | Article having an antimicrobial solid and use thereof |
| ES2658995T3 (es) | 2012-12-26 | 2018-03-13 | Otic Pharma Ltd. | Composiciones farmacéuticas óticas espumables |
| CN105682742A (zh) | 2013-08-27 | 2016-06-15 | 奥德纳米有限公司 | 小儿耳部病症的治疗 |
| US20150119371A1 (en) * | 2013-10-30 | 2015-04-30 | Micro Labs Limited | Topical pharmaceutical compositions of antibiotics and steroidal anti inflammatory agents |
| CN106794144B (zh) | 2014-07-03 | 2020-07-17 | 奥德纳米有限公司 | 环丙沙星组合物的灭菌 |
| US9393243B1 (en) * | 2015-07-14 | 2016-07-19 | Nilesh Parikh | Topical Ciprofloxacin compositions |
| EP3512513A4 (en) | 2016-09-16 | 2020-04-15 | Otonomy, Inc. | OTIC GEL FORMULATIONS FOR THE TREATMENT OF EXTERNAL OTITIS |
| IT201900005280A1 (it) * | 2019-04-05 | 2020-10-05 | Ntc S R L | Composizione otologica |
| USD1042214S1 (en) * | 2023-03-23 | 2024-09-17 | National Chain Company | Jewelry item with charm |
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|---|---|---|---|---|
| US3134718A (en) * | 1963-12-12 | 1964-05-26 | Schering Corp | Pregna-1,4-dienes and compositions containing same |
| US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
| US5223493A (en) * | 1984-12-28 | 1993-06-29 | Alcon Laboratories, Inc. | Anti-inflammatory compounds for ophthalmic use |
| US4686214A (en) * | 1985-10-30 | 1987-08-11 | Alcon Laboratories, Inc. | Anti-inflammatory compounds for ophthalmic use |
| DE3704907A1 (de) * | 1987-02-17 | 1988-08-25 | Bayer Ag | Topisch anwendbare zubereitungen von gyrase-inhibitoren in kombination mit kortikosteroiden |
| AU4201189A (en) * | 1988-08-26 | 1990-03-23 | Alcon Laboratories, Inc. | Combination of quinolone antibiotics and steroids for topical ophthalmic use |
| SU1811833A1 (ru) * | 1989-06-09 | 1993-04-30 | Vladimir I Ivanov | Способ введения лекарственных средств в ухо 2 |
| AU2672892A (en) * | 1991-09-17 | 1993-04-27 | Alcon Laboratories, Inc. | Compositions containing quinolone antibiotics and sulfonate of polystyrol |
| ES2065846B1 (es) | 1993-04-20 | 1995-10-01 | Cusi Lab | Formulacion farmaceutica a base de un agente antiinflamatorio esteroidico o no esteroidico y un antibiotico pertenciente al grupo de los inhibidores de la adn girasa para su utilizacion topica oftalmica. |
| US5540930A (en) * | 1993-10-25 | 1996-07-30 | Pharmos Corporation | Suspension of loteprednol etabonate for ear, eye, or nose treatment |
| US5420120A (en) * | 1993-12-17 | 1995-05-30 | Alcon Laboratories, Inc. | Anti-inflammatory glucocorticoid compounds for topical ophthalmic use |
| ES2078175B1 (es) | 1993-12-31 | 1996-10-16 | Cusi Lab | Formulacion farmaceutica conteniendo clobetasona y tobramicina y sus aplicaciones. |
| ES2079320B1 (es) * | 1994-05-17 | 1996-10-16 | Cusi Lab | Disolucion oftalmica a base de un diclofenaco y tobramicina y sus aplicaciones. |
| US5843930A (en) * | 1995-06-06 | 1998-12-01 | Bayer Corporation | Method of treating otitis with ciprofloxacin-hydrocortisone suspension |
| WO1996039146A1 (en) | 1995-06-06 | 1996-12-12 | Bayer Corporation | Non-irritation, non-sensitizing, non-ototoxic otic antibacterial compositions |
| DE19524691A1 (de) * | 1995-07-06 | 1997-01-09 | Liedtke Pharmed Gmbh | Methode und Zusammensetzung einer topischen Therapie von Innenohr und Labyrinth-Symptomen |
| ES2106680B1 (es) * | 1995-08-03 | 1998-07-01 | Vita Invest Sa | Composiciones acuosas conteniendo ciprofloxacino y utilizacion y procedimiento correspondientes. |
| KR100508227B1 (ko) | 1997-03-14 | 2006-03-23 | 센주 세이야꾸 가부시키가이샤 | 로테프레드놀에타보네이트수성현탁액 |
| AR020661A1 (es) | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento |
| AU6275999A (en) | 1998-09-30 | 2000-04-17 | Alcon Laboratories, Inc. | Antibiotic compositions for treatment of the eye, ear and nose |
| AR020660A1 (es) | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Composiciones antibioticas para el tratamiento de ojos, oidos y nariz |
| US6395746B1 (en) | 1998-09-30 | 2002-05-28 | Alcon Manufacturing, Ltd. | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation |
| DE60006262T2 (de) * | 1999-09-24 | 2004-05-13 | Alcon, Inc. | Topische suspensionsformulierungen enthaltend ciprofloxacin und dexamethason |
| US20030139382A1 (en) * | 2001-09-21 | 2003-07-24 | Alcon, Inc. | Method of treating middle ear infections |
-
2002
- 2002-09-13 US US10/243,341 patent/US20030139382A1/en not_active Abandoned
- 2002-09-13 AT AT02799587T patent/ATE313328T1/de active
- 2002-09-13 RU RU2004111984/14A patent/RU2295346C2/ru active
- 2002-09-13 DE DE60208216T patent/DE60208216T2/de not_active Expired - Lifetime
- 2002-09-13 KR KR10-2004-7003637A patent/KR20040035760A/ko not_active Ceased
- 2002-09-13 WO PCT/US2002/029373 patent/WO2003026671A1/en not_active Ceased
- 2002-09-13 CA CA002459930A patent/CA2459930C/en not_active Expired - Lifetime
- 2002-09-13 CN CNB028183002A patent/CN1231218C/zh not_active Expired - Lifetime
- 2002-09-13 AU AU2002333671A patent/AU2002333671B2/en not_active Expired
- 2002-09-13 BR BR0212898-5A patent/BR0212898A/pt not_active Application Discontinuation
- 2002-09-13 DK DK02799587T patent/DK1429780T3/da active
- 2002-09-13 MX MXPA04002576A patent/MXPA04002576A/es active IP Right Grant
- 2002-09-13 JP JP2003530306A patent/JP2005504804A/ja active Pending
- 2002-09-13 PL PL369205A patent/PL212457B1/pl unknown
- 2002-09-13 ES ES02799587T patent/ES2250739T3/es not_active Expired - Lifetime
- 2002-09-13 EP EP02799587A patent/EP1429780B1/en not_active Expired - Lifetime
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2004
- 2004-03-05 ZA ZA2004/01847A patent/ZA200401847B/en unknown
- 2004-09-22 US US10/946,792 patent/US20050059674A1/en not_active Abandoned
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2006
- 2006-02-21 CY CY20061100244T patent/CY1104988T1/el unknown
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2008
- 2008-05-12 US US12/119,185 patent/US20080214513A1/en not_active Abandoned
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2009
- 2009-02-13 US US12/357,697 patent/US8846650B2/en not_active Expired - Lifetime
-
2013
- 2013-02-21 FR FR13C0012C patent/FR13C0012I2/fr active Active
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2014
- 2014-08-25 US US14/468,257 patent/US9149486B2/en not_active Expired - Fee Related
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2015
- 2015-08-28 US US14/838,637 patent/US9345714B2/en not_active Expired - Fee Related
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2016
- 2016-04-29 US US15/142,225 patent/US9402805B1/en not_active Expired - Fee Related
- 2016-07-29 US US15/223,338 patent/US20160361324A1/en not_active Abandoned
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