ZA200307403B - Disease-associasted protein. - Google Patents
Disease-associasted protein. Download PDFInfo
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- ZA200307403B ZA200307403B ZA200307403A ZA200307403A ZA200307403B ZA 200307403 B ZA200307403 B ZA 200307403B ZA 200307403 A ZA200307403 A ZA 200307403A ZA 200307403 A ZA200307403 A ZA 200307403A ZA 200307403 B ZA200307403 B ZA 200307403B
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- South Africa
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- seq
- polypeptide
- cells
- rdcvf2
- gene
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
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- Chemical Kinetics & Catalysis (AREA)
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- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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JP (2) | JP4370428B2 (ko) |
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CN (1) | CN1529753B (ko) |
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CA (1) | CA2443345C (ko) |
CZ (1) | CZ305800B6 (ko) |
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SK (1) | SK288465B6 (ko) |
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FR2823221B1 (fr) * | 2001-04-06 | 2004-04-02 | Univ Pasteur | Sequences associees a la degenerescence retinienne et applications |
ATE490307T1 (de) | 2003-05-21 | 2010-12-15 | Genzyme Corp | Verfahren zur herstellung von präparationen rekombinanter aav-virionen, die weitgehend frei von leeren capsiden sind |
FR2870241B1 (fr) * | 2004-05-13 | 2015-02-27 | Novartis Ag | Facteur de viabilite des cones derive des batonnets ou rdcvf et applications |
EP2027889A1 (en) * | 2007-06-05 | 2009-02-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | New neuronal viability factor and use thereof |
EP2281047B1 (en) * | 2008-04-15 | 2020-04-08 | Genzyme Corporation | Methods to produce rod-derived cone viability factor (rdcvf) |
ES2548980T3 (es) | 2008-09-10 | 2015-10-22 | Inserm - Institut National De La Santé Et De La Recherche Médicale | Factor de viabilidad neuronal y uso del mismo |
EP2383286A1 (en) | 2010-04-30 | 2011-11-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treatment of retinal degenerative diseases |
AU2012321102C1 (en) * | 2011-10-27 | 2016-11-10 | Pharma Cinq, Llc | Vectors encoding rod-derived cone viability factor |
WO2013124477A1 (en) | 2012-02-24 | 2013-08-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treatment of retinal degenerative diseases |
EP2909232B1 (en) | 2012-10-17 | 2020-03-11 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Methods and pharmaceutical compositions for the treatment of age-related macular degeneration (amd) |
DK3027646T3 (en) | 2013-07-31 | 2018-09-24 | Novartis Ag | New selection vectors and methods for selecting eukaryotic host cells |
WO2016185242A1 (en) * | 2015-05-21 | 2016-11-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Synergistic combination of neuronal viability factors and uses thereof |
US10857240B2 (en) | 2016-01-05 | 2020-12-08 | The Trustees Of The University Of Pennsylvania | Methods and compositions for treatment of ocular disorders and blinding diseases |
CA3025977A1 (en) | 2016-10-11 | 2018-04-19 | Wellstat Ophthalmics Corporation | Fusion protein between short form rod-derived cone viability factor and a hydrophilic peptide |
EP4268895A3 (en) * | 2019-12-09 | 2024-01-10 | Chigenovo Co., Ltd. | Uses of cyp4v2 and rdcvf in preparation of drugs |
CN111733174B (zh) * | 2020-08-07 | 2021-02-09 | 北京大学第三医院(北京大学第三临床医学院) | 一种分离的核酸分子及其用途 |
EP4366757A1 (en) * | 2021-07-07 | 2024-05-15 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Synergistic combination of rdcfv2 and rdcvf2l for the treatment of tauopathies |
CN113774019B (zh) * | 2021-08-11 | 2024-02-13 | 东南大学 | 一种脐带血间充质干细胞无血清培养基、培养方法及其应用 |
WO2024206928A1 (en) | 2023-03-30 | 2024-10-03 | Pharma Cinq, Llc | VECTOR ENCODING ROD-DERIVED CONE VIABILITY FACTOR AND HUMAN IgK SIGNAL SEQUENCE |
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US4771036A (en) * | 1986-02-10 | 1988-09-13 | Trustees Of Columbia University In The City Of New York | Method and ophthalmic composition for the prevention and reversal of cataracts |
GB9701710D0 (en) | 1997-01-28 | 1997-03-19 | Karobio Ab | Mammalian protein |
US6106825A (en) * | 1997-05-07 | 2000-08-22 | University Of Florida | Entomopoxvirus-vertebrate gene delivery vector and method |
FR2784030B1 (fr) * | 1998-10-02 | 2002-12-20 | Inst Nat Sante Rech Med | Utilisation de bloqueurs des canaux calciques et/ou cgmp-dependants pour le traitement de pathologies de la retine |
FR2784898A1 (fr) * | 1998-10-26 | 2000-04-28 | Univ Pasteur | Utilisation du gdnf pour le traitement de la degenerescence retinienne |
EP1033405A3 (en) * | 1999-02-25 | 2001-08-01 | Ceres Incorporated | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby |
EP1242443A4 (en) * | 1999-12-23 | 2005-06-22 | Nuvelo Inc | NEW NUCLEIC ACIDS AND POLYPEPTIDES |
FR2823221B1 (fr) | 2001-04-06 | 2004-04-02 | Univ Pasteur | Sequences associees a la degenerescence retinienne et applications |
US20060275794A1 (en) | 2005-03-07 | 2006-12-07 | Invitrogen Corporation | Collections of matched biological reagents and methods for identifying matched reagents |
ES2548980T3 (es) | 2008-09-10 | 2015-10-22 | Inserm - Institut National De La Santé Et De La Recherche Médicale | Factor de viabilidad neuronal y uso del mismo |
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