ZA200302660B - Mild cosmetic composition with stabilized retinoids. - Google Patents
Mild cosmetic composition with stabilized retinoids. Download PDFInfo
- Publication number
- ZA200302660B ZA200302660B ZA200302660A ZA200302660A ZA200302660B ZA 200302660 B ZA200302660 B ZA 200302660B ZA 200302660 A ZA200302660 A ZA 200302660A ZA 200302660 A ZA200302660 A ZA 200302660A ZA 200302660 B ZA200302660 B ZA 200302660B
- Authority
- ZA
- South Africa
- Prior art keywords
- composition
- retinoid
- oil
- retinyl
- retinol
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 47
- 239000002537 cosmetic Substances 0.000 title claims description 7
- 150000004492 retinoid derivatives Chemical class 0.000 claims description 43
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 33
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 21
- 229960003471 retinol Drugs 0.000 claims description 15
- 239000011607 retinol Substances 0.000 claims description 15
- 235000020944 retinol Nutrition 0.000 claims description 14
- 239000003995 emulsifying agent Substances 0.000 claims description 11
- 239000012530 fluid Substances 0.000 claims description 10
- 125000000946 retinyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 9
- 229920001971 elastomer Polymers 0.000 claims description 8
- 239000000806 elastomer Substances 0.000 claims description 8
- 150000002148 esters Chemical class 0.000 claims description 7
- 239000003906 humectant Substances 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 7
- 229920002545 silicone oil Polymers 0.000 claims description 6
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims description 5
- 229930002330 retinoic acid Natural products 0.000 claims description 5
- 229960001727 tretinoin Drugs 0.000 claims description 5
- 150000001298 alcohols Chemical class 0.000 claims description 3
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 3
- 239000000194 fatty acid Substances 0.000 claims description 3
- 229930195729 fatty acid Natural products 0.000 claims description 3
- 150000004665 fatty acids Chemical class 0.000 claims description 3
- 125000001165 hydrophobic group Chemical group 0.000 claims description 3
- 229930195733 hydrocarbon Natural products 0.000 claims description 2
- 150000002430 hydrocarbons Chemical class 0.000 claims description 2
- 239000007764 o/w emulsion Substances 0.000 claims description 2
- 230000002207 retinal effect Effects 0.000 claims description 2
- NCYCYZXNIZJOKI-OVSJKPMPSA-N retinal group Chemical group C\C(=C/C=O)\C=C\C=C(\C=C\C1=C(CCCC1(C)C)C)/C NCYCYZXNIZJOKI-OVSJKPMPSA-N 0.000 claims description 2
- 150000005846 sugar alcohols Polymers 0.000 claims description 2
- 239000003921 oil Substances 0.000 description 19
- -1 retinyl formate Chemical compound 0.000 description 14
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 13
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 9
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 9
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- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 5
- 229940008099 dimethicone Drugs 0.000 description 5
- 239000004205 dimethyl polysiloxane Substances 0.000 description 5
- 235000011187 glycerol Nutrition 0.000 description 5
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 4
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 4
- XWCYDHJOKKGVHC-UHFFFAOYSA-N Vitamin A2 Chemical compound OCC=C(C)C=CC=C(C)C=CC1=C(C)C=CCC1(C)C XWCYDHJOKKGVHC-UHFFFAOYSA-N 0.000 description 4
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 4
- 238000004128 high performance liquid chromatography Methods 0.000 description 4
- 229920001296 polysiloxane Polymers 0.000 description 4
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 239000011717 all-trans-retinol Substances 0.000 description 3
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- SAMYFBLRCRWESN-UHFFFAOYSA-N 16-methylheptadecyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCCCC(C)C SAMYFBLRCRWESN-UHFFFAOYSA-N 0.000 description 2
- OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-MKOSUFFBSA-N 9-cis-retinol Chemical compound OC\C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-MKOSUFFBSA-N 0.000 description 2
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
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- 229920002125 Sokalan® Polymers 0.000 description 2
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- FXKDHZXYYBPLHI-TUTABMRPSA-N all-trans-retinyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FXKDHZXYYBPLHI-TUTABMRPSA-N 0.000 description 2
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- 229920006037 cross link polymer Polymers 0.000 description 2
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- 238000006731 degradation reaction Methods 0.000 description 2
- FPIPGXGPPPQFEQ-DPZDGVIMSA-N dihydroretinol Natural products CC(=CCO)C=CC=C(C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-DPZDGVIMSA-N 0.000 description 2
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 229940113915 isostearyl palmitate Drugs 0.000 description 2
- CBKLICUQYUTWQL-XWGBWKJCSA-N methyl (3s,4r)-3-methyl-1-(2-phenylethyl)-4-(n-propanoylanilino)piperidine-4-carboxylate;oxalic acid Chemical compound OC(=O)C(O)=O.CCC(=O)N([C@]1([C@H](CN(CCC=2C=CC=CC=2)CC1)C)C(=O)OC)C1=CC=CC=C1 CBKLICUQYUTWQL-XWGBWKJCSA-N 0.000 description 2
- BARWIPMJPCRCTP-CLFAGFIQSA-N oleyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC BARWIPMJPCRCTP-CLFAGFIQSA-N 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 229960000342 retinol acetate Drugs 0.000 description 2
- 235000019173 retinyl acetate Nutrition 0.000 description 2
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- WWDMJSSVVPXVSV-YCNIQYBTSA-N retinyl ester Chemical compound CC1CCCC(C)(C)C1\C=C\C(\C)=C\C=C\C(\C)=C\C(O)=O WWDMJSSVVPXVSV-YCNIQYBTSA-N 0.000 description 2
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- 102000018822 Retinal Dehydrogenase Human genes 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/062—Oil-in-water emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25269600P | 2000-11-22 | 2000-11-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200302660B true ZA200302660B (en) | 2004-04-05 |
Family
ID=22957123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200302660A ZA200302660B (en) | 2000-11-22 | 2001-11-19 | Mild cosmetic composition with stabilized retinoids. |
Country Status (14)
Country | Link |
---|---|
US (1) | US6881414B2 (de) |
EP (1) | EP1351651B1 (de) |
JP (1) | JP3946140B2 (de) |
KR (1) | KR100860423B1 (de) |
CN (1) | CN1329019C (de) |
AR (1) | AR031494A1 (de) |
AT (1) | ATE418318T1 (de) |
AU (2) | AU2486102A (de) |
CA (1) | CA2426635C (de) |
DE (1) | DE60137144D1 (de) |
MX (1) | MXPA03004366A (de) |
TW (1) | TWI287454B (de) |
WO (1) | WO2002041849A2 (de) |
ZA (1) | ZA200302660B (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020168389A1 (en) * | 2000-12-28 | 2002-11-14 | Prem Chandar | Stable skin conditioning compositions containing retinoid boosters |
JP2003104827A (ja) * | 2001-09-28 | 2003-04-09 | Kose Corp | 化粧料 |
US7351417B2 (en) * | 2003-03-17 | 2008-04-01 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Silky feel cosmetic emulsion chassis |
GB0311815D0 (en) * | 2003-05-22 | 2003-06-25 | Unilever Plc | Skin treatments |
DE102004003478A1 (de) * | 2004-01-22 | 2005-08-18 | Basf Ag | Retinoid-haltige Zubereitungen |
US8017136B2 (en) * | 2004-05-24 | 2011-09-13 | The Procter & Gamble Company | Shiny foundation |
JP4726598B2 (ja) * | 2005-10-03 | 2011-07-20 | ポーラ化成工業株式会社 | 水中油保湿皮膚外用剤 |
JP5746807B2 (ja) * | 2006-12-28 | 2015-07-08 | アルロン・ジャパン株式会社 | 皮膚用化粧品の組成物 |
CN101249095B (zh) * | 2007-10-08 | 2011-08-31 | 重庆医药工业研究院有限责任公司 | 一种含脱色剂、维a酸和皮质类固醇的乳膏的制备方法 |
FR2927252B1 (fr) * | 2008-02-12 | 2010-04-23 | Oreal | Emulsion huile-dans-eau contenant un polyere amphiphile |
US20090317341A1 (en) * | 2008-06-18 | 2009-12-24 | Conopco, Inc., D/B/A Unilever | Compositions for Lightening Skin Color |
US8337870B2 (en) * | 2009-12-15 | 2012-12-25 | Young Pharmaceuticals, Inc. | Low toxicity topical active agent delivery system |
FR2991175B1 (fr) * | 2012-06-01 | 2014-12-19 | Galderma Res & Dev | Compositions pharmaceutiques topiques de type emulsion h/e contenant un retinoide |
CN103565676B (zh) * | 2013-11-08 | 2015-08-26 | 江南大学 | 一种两亲性聚合物包覆的类维生素a包覆胶束及化妆品组合物 |
KR101908347B1 (ko) * | 2014-12-31 | 2018-10-17 | (주)아모레퍼시픽 | 화학적 비대칭 이방성 분체 및 이를 함유하는 유중수화(w/o) 유화 조성물 |
CN106582066A (zh) * | 2016-11-24 | 2017-04-26 | 上海交通大学 | 肉桂酸酯类紫外防晒剂分子印迹固相萃取柱及制备与应用 |
US10350153B2 (en) * | 2017-03-31 | 2019-07-16 | Johnson & Johnson Consumer Inc. | Topical compositions comprising retinoids and low irritation polymeric cleansing agents |
JP7456939B2 (ja) * | 2018-12-28 | 2024-03-27 | 株式会社 資生堂 | レチノール含有水中油型乳化化粧料 |
WO2021195931A1 (en) * | 2020-03-31 | 2021-10-07 | L'oreal | Cosmetic composition in the form of a gel |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2503426B2 (ja) * | 1986-08-01 | 1996-06-05 | トヨタ自動車株式会社 | 自動変速機搭載車両のブレ−キ制御装置 |
KR930001805B1 (ko) | 1989-10-02 | 1993-03-13 | 브리스톨-마이어즈 스퀴브 컴페니 | 안정성이 개선된 트리티노인 유화크림 제제 |
KR940000322B1 (ko) * | 1991-07-08 | 1994-01-17 | 유춘우 | 인스탄트 수제비의 제조방법 |
FR2753626B1 (fr) | 1996-09-20 | 1998-11-06 | Centre International De Rech Dermatologiques Galderma Cird Galderma | Nouvelles compositions topiques sous forme d'emulsion fluide h/e a forte teneur en glycol pro-penetrant |
US5744148A (en) * | 1996-09-20 | 1998-04-28 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Stabilization of an unstable retinoid in oil-in-water emulsions for skin care compositions |
WO1998022084A1 (en) | 1996-11-19 | 1998-05-28 | The Procter & Gamble Company | Skin care compositions |
US5935589A (en) | 1997-10-17 | 1999-08-10 | Chesebrough-Pond's Usa Co. | Stable cosmetic compositions with different pH emulsions |
US5997887A (en) | 1997-11-10 | 1999-12-07 | The Procter & Gamble Company | Skin care compositions and method of improving skin appearance |
JP2000044458A (ja) | 1998-07-30 | 2000-02-15 | Shiseido Co Ltd | 皮膚外用剤 |
FR2782924B1 (fr) * | 1998-09-09 | 2001-10-26 | Oreal | Emulsion h/e/h stable et son utilisation comme composition cosmetique et/ou dermatologique |
MXPA00003830A (es) * | 1999-04-20 | 2005-09-08 | Schering Plough Healthcare | Composiciones de bronceado sin exposicion solar que contienen agentes colorantes. |
KR20020025804A (ko) | 2000-09-29 | 2002-04-04 | 미쉘 지. 멘지니 | 국소적 피부 약제의 침투성을 강화하기 위한 조성물 |
-
2001
- 2001-11-01 US US09/998,958 patent/US6881414B2/en not_active Expired - Lifetime
- 2001-11-19 KR KR1020037006861A patent/KR100860423B1/ko not_active IP Right Cessation
- 2001-11-19 CA CA2426635A patent/CA2426635C/en not_active Expired - Lifetime
- 2001-11-19 WO PCT/EP2001/013405 patent/WO2002041849A2/en active Application Filing
- 2001-11-19 AT AT01994681T patent/ATE418318T1/de not_active IP Right Cessation
- 2001-11-19 DE DE60137144T patent/DE60137144D1/de not_active Revoked
- 2001-11-19 AU AU2486102A patent/AU2486102A/xx active Pending
- 2001-11-19 AU AU2002224861A patent/AU2002224861B2/en not_active Ceased
- 2001-11-19 MX MXPA03004366A patent/MXPA03004366A/es active IP Right Grant
- 2001-11-19 ZA ZA200302660A patent/ZA200302660B/en unknown
- 2001-11-19 JP JP2002544029A patent/JP3946140B2/ja not_active Expired - Lifetime
- 2001-11-19 EP EP01994681A patent/EP1351651B1/de not_active Revoked
- 2001-11-19 CN CNB018193072A patent/CN1329019C/zh not_active Expired - Fee Related
- 2001-11-20 TW TW090128745A patent/TWI287454B/zh not_active IP Right Cessation
- 2001-11-22 AR ARP010105445A patent/AR031494A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR100860423B1 (ko) | 2008-09-25 |
CA2426635A1 (en) | 2002-05-30 |
WO2002041849A2 (en) | 2002-05-30 |
WO2002041849A3 (en) | 2003-07-31 |
AU2002224861B2 (en) | 2006-03-02 |
WO2002041849B1 (en) | 2004-03-04 |
JP2004513959A (ja) | 2004-05-13 |
KR20030062351A (ko) | 2003-07-23 |
MXPA03004366A (es) | 2003-08-19 |
EP1351651B1 (de) | 2008-12-24 |
CN1329019C (zh) | 2007-08-01 |
JP3946140B2 (ja) | 2007-07-18 |
CN1538833A (zh) | 2004-10-20 |
TWI287454B (en) | 2007-10-01 |
AU2486102A (en) | 2002-06-03 |
CA2426635C (en) | 2013-02-05 |
US6881414B2 (en) | 2005-04-19 |
AR031494A1 (es) | 2003-09-24 |
DE60137144D1 (de) | 2009-02-05 |
EP1351651A2 (de) | 2003-10-15 |
ATE418318T1 (de) | 2009-01-15 |
US20020110572A1 (en) | 2002-08-15 |
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