ZA200207802B - Indolin-2-one derivatives, preparation and their use as ocytocin receptor ligands. - Google Patents

Indolin-2-one derivatives, preparation and their use as ocytocin receptor ligands. Download PDF

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Publication number
ZA200207802B
ZA200207802B ZA200207802A ZA200207802A ZA200207802B ZA 200207802 B ZA200207802 B ZA 200207802B ZA 200207802 A ZA200207802 A ZA 200207802A ZA 200207802 A ZA200207802 A ZA 200207802A ZA 200207802 B ZA200207802 B ZA 200207802B
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South Africa
Prior art keywords
chloro
group
methyl
dimethoxybenzyl
oxoindolin
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ZA200207802A
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English (en)
Inventor
Loic Foulon
Georges Garcia
Claudine Serradeil-Le Gal
Gerard Valette
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Sanofi Synthelabo
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Publication of ZA200207802B publication Critical patent/ZA200207802B/en

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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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ZA200207802A 2000-04-03 2002-09-27 Indolin-2-one derivatives, preparation and their use as ocytocin receptor ligands. ZA200207802B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0004193A FR2807038B1 (fr) 2000-04-03 2000-04-03 Nouveaux derives d'indolin-2-one, leur preparation et les compositions pharmaceutiques les contenant

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ZA200207802B true ZA200207802B (en) 2003-09-29

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ZA200207802A ZA200207802B (en) 2000-04-03 2002-09-27 Indolin-2-one derivatives, preparation and their use as ocytocin receptor ligands.

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US (2) US20040059132A1 (is)
EP (1) EP1272468B1 (is)
JP (1) JP2003529586A (is)
KR (1) KR100765028B1 (is)
CN (1) CN1224614C (is)
AR (1) AR034547A1 (is)
AT (1) ATE282593T1 (is)
AU (2) AU2001246671B2 (is)
BR (1) BR0109814A (is)
CA (1) CA2404592A1 (is)
CZ (1) CZ20023297A3 (is)
DE (1) DE60107221T2 (is)
DK (1) DK1272468T3 (is)
EA (1) EA005093B1 (is)
EE (1) EE05002B1 (is)
ES (1) ES2232610T3 (is)
FR (1) FR2807038B1 (is)
HK (1) HK1050004A1 (is)
HU (1) HUP0303109A3 (is)
IL (1) IL152085A0 (is)
IS (1) IS2458B (is)
ME (1) MEP24308A (is)
MX (1) MXPA02009773A (is)
NO (1) NO324314B1 (is)
NZ (1) NZ521617A (is)
PL (1) PL358222A1 (is)
PT (1) PT1272468E (is)
SI (1) SI1272468T1 (is)
SK (1) SK14272002A3 (is)
TR (1) TR200202288T2 (is)
TW (1) TWI225860B (is)
UA (1) UA73163C2 (is)
WO (1) WO2001074775A1 (is)
YU (1) YU80902A (is)
ZA (1) ZA200207802B (is)

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TWI289141B (en) 2003-03-11 2007-11-01 Hoffmann La Roche F. Ag. Quinolinone derivatives and uses thereof
FR2875499B1 (fr) * 2004-09-20 2006-10-27 Sanofi Aventis Sa Nouveaux derives pyridiniques d'indolin-2-one, leur preparation et leur application en therapeutique
AR053710A1 (es) 2005-04-11 2007-05-16 Xenon Pharmaceuticals Inc Compuestos espiroheterociclicos y sus usos como agentes terapeuticos
AR056968A1 (es) 2005-04-11 2007-11-07 Xenon Pharmaceuticals Inc Compuestos espiro-oxindol y composiciones farmacéuticas
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WO2007063123A1 (de) * 2005-12-02 2007-06-07 Abbott Gmbh & Co. Kg Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung
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MX2009003876A (es) 2006-10-12 2009-05-11 Xenon Pharmaceuticals Inc Uso de compuestos de espiro-oxindol como agentes terapeuticos.
WO2008046083A2 (en) * 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Use of oxindole compounds as therapeutic agents
FR2909668B1 (fr) * 2006-12-12 2009-01-23 Sanofi Aventis Sa Derives de 5-alkyloxy-indolin-2-one,leur preparation et leurs applications en therapeutique
CA2741024A1 (en) 2008-10-17 2010-04-22 Xenon Pharmaceuticals Inc. Spiro-oxindole compounds and their use as therapeutic agents
KR101286323B1 (ko) 2008-10-17 2013-07-15 제논 파마슈티칼스 인크. 스피로-옥스인돌 화합물 및 치료제로서의 그의 용도
AR077252A1 (es) 2009-06-29 2011-08-10 Xenon Pharmaceuticals Inc Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
MY165579A (en) 2009-10-14 2018-04-05 Xenon Pharmaceuticals Inc Synthetic methods for spiro-oxindole compounds
CN105726531A (zh) 2010-02-26 2016-07-06 泽农医药公司 用于局部给药的螺-羟吲哚化合物的药物组合物及其作为治疗剂的用途
CN103623268B (zh) * 2013-12-04 2015-07-15 张国显 神经康复再造丸及其制备方法
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