ZA200207755B - Simethicone solid oral dosage form. - Google Patents
Simethicone solid oral dosage form.Info
- Publication number
- ZA200207755B ZA200207755B ZA200207755A ZA200207755A ZA200207755B ZA 200207755 B ZA200207755 B ZA 200207755B ZA 200207755 A ZA200207755 A ZA 200207755A ZA 200207755 A ZA200207755 A ZA 200207755A ZA 200207755 B ZA200207755 B ZA 200207755B
- Authority
- ZA
- South Africa
- Prior art keywords
- dosage form
- oral dosage
- solid oral
- simethicone solid
- simethicone
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/966,441 US7101573B2 (en) | 2001-09-28 | 2001-09-28 | Simethicone solid oral dosage form |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200207755B true ZA200207755B (en) | 2004-03-26 |
Family
ID=25511414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200207755A ZA200207755B (en) | 2001-09-28 | 2002-09-26 | Simethicone solid oral dosage form. |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US7101573B2 (xx) |
| EP (1) | EP1297825B1 (xx) |
| AR (1) | AR036700A1 (xx) |
| AT (1) | ATE296619T1 (xx) |
| AU (1) | AU2002301259C1 (xx) |
| BR (1) | BR0204001A (xx) |
| CA (1) | CA2405190C (xx) |
| CO (1) | CO5390073A1 (xx) |
| DE (1) | DE60204403T2 (xx) |
| DK (1) | DK1297825T3 (xx) |
| ES (1) | ES2243664T3 (xx) |
| HU (1) | HUP0203176A2 (xx) |
| MX (1) | MXPA02009570A (xx) |
| NZ (1) | NZ521657A (xx) |
| PL (1) | PL204141B1 (xx) |
| PT (1) | PT1297825E (xx) |
| RU (1) | RU2362569C2 (xx) |
| ZA (1) | ZA200207755B (xx) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6632429B1 (en) * | 1999-12-17 | 2003-10-14 | Joan M. Fallon | Methods for treating pervasive development disorders |
| US7985420B2 (en) * | 2000-04-28 | 2011-07-26 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
| US6955821B2 (en) | 2000-04-28 | 2005-10-18 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
| US8012504B2 (en) * | 2000-04-28 | 2011-09-06 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
| US7838032B2 (en) * | 2000-04-28 | 2010-11-23 | Reckitt Benckiser Inc. | Sustained release of guaifenesin |
| US20070053895A1 (en) | 2000-08-14 | 2007-03-08 | Fallon Joan M | Method of treating and diagnosing parkinsons disease and related dysautonomic disorders |
| US8030002B2 (en) | 2000-11-16 | 2011-10-04 | Curemark Llc | Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions |
| US7101573B2 (en) * | 2001-09-28 | 2006-09-05 | Mcneil-Pcc, Inc. | Simethicone solid oral dosage form |
| US7179488B2 (en) | 2001-11-29 | 2007-02-20 | Bob Sherwood | Process for co-spray drying liquid herbal extracts with dry silicified MCC |
| AU2002219964A1 (en) * | 2001-11-29 | 2003-06-17 | Penwest Pharmaceutical Company | Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose |
| SE0200895D0 (sv) * | 2002-03-22 | 2002-03-22 | Astrazeneca Ab | New pharmaceutical composition |
| US7341742B2 (en) * | 2002-09-30 | 2008-03-11 | L. Perrigo Company | Simethicone containing tablet composition and method |
| EP1563837A1 (en) * | 2004-02-03 | 2005-08-17 | Ferrer Internacional, S.A. | Hypocholesterolemic compositions comprising a statin and an antiflatulent agent |
| CA2559239C (en) * | 2004-04-13 | 2021-04-06 | Boehringer Ingelheim International Gmbh | Use of simethicone and sodium picosulphate in constipated patients suffering from bloated feeling and gas discomfort during the night |
| US20080255104A1 (en) * | 2004-05-04 | 2008-10-16 | Equitech Corporation | Nsaid Compositions |
| US20060024409A1 (en) * | 2004-07-29 | 2006-02-02 | Everett Laboratories, Inc. | Compositions and methods for nutrition supplementation |
| US20060024384A1 (en) * | 2004-07-29 | 2006-02-02 | Giordano John A | Compositions and methods for nutrition supplementation |
| US20060198838A1 (en) * | 2004-09-28 | 2006-09-07 | Fallon Joan M | Combination enzyme for cystic fibrosis |
| KR101483297B1 (ko) * | 2005-03-24 | 2015-01-21 | 다이이찌 산쿄 가부시키가이샤 | 의약용 조성물 |
| BRPI0615607A2 (pt) * | 2005-08-30 | 2011-05-24 | Lek Pharmaceuticals | composição farmacêutica compreendendo perindopril ou seus sais |
| US20080058282A1 (en) | 2005-08-30 | 2008-03-06 | Fallon Joan M | Use of lactulose in the treatment of autism |
| KR101252635B1 (ko) * | 2006-04-20 | 2013-04-10 | (주)아모레퍼시픽 | 리파아제 저해제 및 친유성 오일흡수제를 포함하는 약학조성물 및 이로부터 제조된 경구 투여용 제제 |
| US20080015260A1 (en) * | 2006-07-13 | 2008-01-17 | Kiel Laboratories, Inc. | Pharmaceutical compositions having improved stability and methods for preparation and use |
| US20080038410A1 (en) * | 2006-08-18 | 2008-02-14 | Everett Laboratories, Inc. | Compositions and methods for nutrition supplementation |
| CA2667682A1 (en) | 2006-10-27 | 2008-05-15 | The Curators Of The University Of Missouri | Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same |
| WO2008056200A1 (en) * | 2006-11-10 | 2008-05-15 | Ranbaxy Laboratories Limited | Oral pharmaceutical compositions of simethicone |
| KR20090088913A (ko) | 2006-11-21 | 2009-08-20 | 맥네일-피피씨, 인코포레이티드 | 개질된 방출형 진통 현탁제 |
| US9833510B2 (en) * | 2007-06-12 | 2017-12-05 | Johnson & Johnson Consumer Inc. | Modified release solid or semi-solid dosage forms |
| US20090004248A1 (en) * | 2007-06-29 | 2009-01-01 | Frank Bunick | Dual portion dosage lozenge form |
| US8247440B2 (en) | 2008-02-20 | 2012-08-21 | Curators Of The University Of Missouri | Composition comprising omeprazole, lansoprazole and at least one buffering agent |
| US8658163B2 (en) | 2008-03-13 | 2014-02-25 | Curemark Llc | Compositions and use thereof for treating symptoms of preeclampsia |
| US8084025B2 (en) | 2008-04-18 | 2011-12-27 | Curemark Llc | Method for the treatment of the symptoms of drug and alcohol addiction |
| US9320780B2 (en) | 2008-06-26 | 2016-04-26 | Curemark Llc | Methods and compositions for the treatment of symptoms of Williams Syndrome |
| PL2318035T3 (pl) | 2008-07-01 | 2019-10-31 | Curemark Llc | Sposoby i kompozycje do leczenia objawów zaburzeń neurologicznych i zaburzeń zdrowia psychicznego |
| US10776453B2 (en) | 2008-08-04 | 2020-09-15 | Galenagen, Llc | Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain |
| US20100092447A1 (en) | 2008-10-03 | 2010-04-15 | Fallon Joan M | Methods and compositions for the treatment of symptoms of prion diseases |
| WO2010080835A1 (en) | 2009-01-06 | 2010-07-15 | Curemark Llc | Compositions and methods for the treatment or the prevention oral infections by e. coli |
| WO2010080830A1 (en) | 2009-01-06 | 2010-07-15 | Curemark Llc | Compositions and methods for the treatment or prevention of staphylococcus aureus infections and for the eradication or reduction of staphylococcus aureus on surfaces |
| US20100247586A1 (en) * | 2009-03-27 | 2010-09-30 | Andreas Hugerth | Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties |
| JP5410819B2 (ja) * | 2009-04-09 | 2014-02-05 | ライオン株式会社 | 木クレオソート含有固形製剤 |
| US9056050B2 (en) | 2009-04-13 | 2015-06-16 | Curemark Llc | Enzyme delivery systems and methods of preparation and use |
| US9511125B2 (en) | 2009-10-21 | 2016-12-06 | Curemark Llc | Methods and compositions for the treatment of influenza |
| CN106310242B (zh) | 2011-04-21 | 2020-02-28 | 柯尔马克有限责任公司 | 用于治疗神经精神障碍的化合物 |
| JP2014516080A (ja) | 2011-06-08 | 2014-07-07 | エスティーアイ ファーマ， エルエルシー | 一日一回の投与のための吸収が制御された水溶性の薬学的に活性な有機化合物製剤 |
| HUE031435T2 (en) * | 2011-09-08 | 2017-07-28 | Mereo Biopharma 2 Ltd | Pharmaceutical compositions comprising an aromatase inhibitor |
| BR112014009946A2 (pt) * | 2011-10-27 | 2017-04-25 | Salix Pharmaceuticals Inc | "composição, composição farmacêutica ou formulação purgativas e uso das mesmas" |
| ITMI20112221A1 (it) * | 2011-12-05 | 2013-06-06 | Altergon Sa | Formulazioni stabili in capsule di gelatina molle di antiaggreganti piastrinici, acidi grassi omega-3 e amilosio |
| IN2014MN01382A (xx) | 2011-12-14 | 2015-04-17 | Disphar Int Bv | |
| RU2491941C1 (ru) * | 2011-12-27 | 2013-09-10 | Вадим Алексеевич Козловский | Композиционный энтеросорбент |
| US10350278B2 (en) | 2012-05-30 | 2019-07-16 | Curemark, Llc | Methods of treating Celiac disease |
| MA41620A (fr) | 2015-05-14 | 2018-01-09 | Abdi Ibrahim Ilac Sanayi Ve Ticaret A S | Composition pharmaceutique comprenant de la siméthicone et de l'otilonium |
| JP6724537B2 (ja) * | 2015-05-26 | 2020-07-15 | 大正製薬株式会社 | 固形製剤 |
| WO2016201119A1 (en) * | 2015-06-09 | 2016-12-15 | J. Rettenmaier & Söhne Gmbh + Co Kg | Excipient and oral solid dosage forms for oily drugs |
| US10166185B2 (en) * | 2015-06-09 | 2019-01-01 | J. Rettenmaier & Söhne Gmbh + Co Kg | Excipient and oral solid dosage forms for oily drugs |
| US20180311201A1 (en) | 2015-06-12 | 2018-11-01 | Santa Farma ?Laç Sanay? A. ?. | Oral pharmaceutical composition comprising otilonium bromide and simethicone with certain bulk density and improved dissolution characteristics |
| US11278506B2 (en) | 2015-10-09 | 2022-03-22 | Rb Health (Us) Llc | Pharmaceutical formulation |
| MX2016016587A (es) * | 2016-12-14 | 2018-06-13 | Rhein Siegfried Sa De Cv | Composicion mejorada de lansoprazol y simeticona y procesos para prepararla. |
| CA3076413A1 (en) | 2017-09-29 | 2019-04-04 | Johnson & Johnson Consumer Inc. | Solid simethicone particles and dosage form thereof |
| US11541009B2 (en) | 2020-09-10 | 2023-01-03 | Curemark, Llc | Methods of prophylaxis of coronavirus infection and treatment of coronaviruses |
| FR3117780B1 (fr) * | 2020-12-22 | 2024-04-05 | Oreal | Composition anhydre sous forme de poudre compacte comprenant un sel de magnesium et de la cellulose microcristalline |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56169622A (en) * | 1980-06-03 | 1981-12-26 | Kissei Pharmaceut Co Ltd | Method of making solid preparation from oily substance |
| US4744987A (en) * | 1985-03-08 | 1988-05-17 | Fmc Corporation | Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation |
| US4851226A (en) | 1987-11-16 | 1989-07-25 | Mcneil Consumer Products Company | Chewable medicament tablet containing means for taste masking |
| US4906478A (en) | 1988-12-12 | 1990-03-06 | Valentine Enterprises, Inc. | Simethicone/calcium silicate composition |
| US5073384A (en) | 1989-10-19 | 1991-12-17 | Valentine Enterprises, Inc. | Maltodextrin/defoaming composition combinate |
| US5275822A (en) | 1989-10-19 | 1994-01-04 | Valentine Enterprises, Inc. | Defoaming composition |
| NZ235876A (en) * | 1989-11-01 | 1992-06-25 | Mcneil Ppc Inc | Pharmaceutical compositions containing effective amount of antidiarrheal composition and antiflatulent effective amount of simethicone |
| US5075114A (en) | 1990-05-23 | 1991-12-24 | Mcneil-Ppc, Inc. | Taste masking and sustained release coatings for pharmaceuticals |
| CA2068402C (en) | 1991-06-14 | 1998-09-22 | Michael R. Hoy | Taste mask coatings for preparation of chewable pharmaceutical tablets |
| JP3177707B2 (ja) | 1991-10-08 | 2001-06-18 | 堀井薬品工業株式会社 | 消化管内ガス除去剤 |
| HU215958B (hu) * | 1992-04-30 | 1999-03-29 | Schering Corp. | Eljárás stabil, hidratált, száraz ceftibuten porkészítmény előállítására perorális szuszpenziókhoz |
| GR1002332B (el) * | 1992-05-21 | 1996-05-16 | Mcneil-Ppc Inc. | Νεες φαρμακευτικες συνθεσεις που περιεχουν σιμεθεικονη. |
| CA2110313C (en) * | 1992-12-01 | 2004-10-26 | Edward John Roche | Pharmaceutical compositions containing a guanidinothiazole compound and antacids |
| FR2705966B1 (fr) | 1993-06-04 | 1995-08-25 | Dow Corning Sa | Compositions antimousse utiles notamment pour le traitement de troubles gastriques. |
| JPH09504293A (ja) * | 1993-10-28 | 1997-04-28 | ザ、プロクター、エンド、ギャンブル、カンパニー | マグネシウムアルミニウムシリケート及び複数の活性成分を含有した速溶解性剤形 |
| EP0659403B1 (en) | 1993-12-15 | 2001-03-14 | National Starch and Chemical Investment Holding Corporation | Use of oil adsorbent natural polymer for cosmetic and pharmaceutical applications |
| US6106865A (en) * | 1995-01-09 | 2000-08-22 | Edward Mendell Co., Inc. | Pharmaceutical excipient having improved compressibility |
| US5585115A (en) * | 1995-01-09 | 1996-12-17 | Edward H. Mendell Co., Inc. | Pharmaceutical excipient having improved compressability |
| IL139728A (en) * | 1995-01-09 | 2003-06-24 | Penwest Pharmaceuticals Compan | Aqueous slurry composition containing microcrystalline cellulose for preparing a pharmaceutical excipient |
| US6103260A (en) * | 1997-07-17 | 2000-08-15 | Mcneil-Ppc, Inc. | Simethicone/anhydrous calcium phosphate compositions |
| US6190696B1 (en) * | 1998-06-08 | 2001-02-20 | Pieter J. Groenewoud | Stabilized thyroxine medications |
| US6126967A (en) | 1998-09-03 | 2000-10-03 | Ascent Pediatrics | Extended release acetaminophen particles |
| US7101573B2 (en) * | 2001-09-28 | 2006-09-05 | Mcneil-Pcc, Inc. | Simethicone solid oral dosage form |
-
2001
- 2001-09-28 US US09/966,441 patent/US7101573B2/en not_active Expired - Lifetime
-
2002
- 2002-09-25 CA CA2405190A patent/CA2405190C/en not_active Expired - Fee Related
- 2002-09-26 ZA ZA200207755A patent/ZA200207755B/xx unknown
- 2002-09-26 HU HU0203176A patent/HUP0203176A2/hu unknown
- 2002-09-27 EP EP02256741A patent/EP1297825B1/en not_active Expired - Lifetime
- 2002-09-27 PT PT02256741T patent/PT1297825E/pt unknown
- 2002-09-27 ES ES02256741T patent/ES2243664T3/es not_active Expired - Lifetime
- 2002-09-27 RU RU2002125821/15A patent/RU2362569C2/ru not_active IP Right Cessation
- 2002-09-27 CO CO02087102A patent/CO5390073A1/es not_active Application Discontinuation
- 2002-09-27 MX MXPA02009570A patent/MXPA02009570A/es active IP Right Grant
- 2002-09-27 AU AU2002301259A patent/AU2002301259C1/en not_active Ceased
- 2002-09-27 DK DK02256741T patent/DK1297825T3/da active
- 2002-09-27 AR ARP020103669A patent/AR036700A1/es not_active Application Discontinuation
- 2002-09-27 DE DE60204403T patent/DE60204403T2/de not_active Expired - Lifetime
- 2002-09-27 PL PL356358A patent/PL204141B1/pl unknown
- 2002-09-27 NZ NZ521657A patent/NZ521657A/en unknown
- 2002-09-27 AT AT02256741T patent/ATE296619T1/de not_active IP Right Cessation
- 2002-09-30 BR BR0204001-8A patent/BR0204001A/pt not_active Application Discontinuation
-
2006
- 2006-07-28 US US11/460,741 patent/US7691409B2/en not_active Expired - Lifetime
-
2010
- 2010-02-03 US US12/699,129 patent/US20100135982A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CO5390073A1 (es) | 2004-04-30 |
| NZ521657A (en) | 2004-05-28 |
| HUP0203176A2 (hu) | 2004-07-28 |
| DE60204403D1 (de) | 2005-07-07 |
| ATE296619T1 (de) | 2005-06-15 |
| US7691409B2 (en) | 2010-04-06 |
| AU2002301259B2 (en) | 2009-01-22 |
| RU2002125821A (ru) | 2004-03-27 |
| US20100135982A1 (en) | 2010-06-03 |
| US20030091624A1 (en) | 2003-05-15 |
| ES2243664T3 (es) | 2005-12-01 |
| PL204141B1 (pl) | 2009-12-31 |
| CA2405190A1 (en) | 2003-03-28 |
| HU0203176D0 (xx) | 2002-11-28 |
| US20070196468A1 (en) | 2007-08-23 |
| RU2362569C2 (ru) | 2009-07-27 |
| EP1297825B1 (en) | 2005-06-01 |
| AR036700A1 (es) | 2004-09-29 |
| DE60204403T2 (de) | 2006-05-04 |
| PL356358A1 (en) | 2003-04-07 |
| MXPA02009570A (es) | 2004-07-30 |
| AU2002301259C1 (en) | 2009-07-23 |
| CA2405190C (en) | 2010-11-09 |
| BR0204001A (pt) | 2003-09-16 |
| DK1297825T3 (da) | 2005-09-26 |
| US7101573B2 (en) | 2006-09-05 |
| PT1297825E (pt) | 2005-08-31 |
| EP1297825A1 (en) | 2003-04-02 |
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