ZA200105823B - p53 inhibitors and therapeutic use of the same. - Google Patents
p53 inhibitors and therapeutic use of the same. Download PDFInfo
- Publication number
- ZA200105823B ZA200105823B ZA200105823A ZA200105823A ZA200105823B ZA 200105823 B ZA200105823 B ZA 200105823B ZA 200105823 A ZA200105823 A ZA 200105823A ZA 200105823 A ZA200105823 A ZA 200105823A ZA 200105823 B ZA200105823 B ZA 200105823B
- Authority
- ZA
- South Africa
- Prior art keywords
- inhibitor
- temporary
- alkyl
- therapeutically effective
- cancer
- Prior art date
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
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- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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US (7) | US6593353B1 (fr) |
EP (1) | EP1143943B1 (fr) |
JP (2) | JP2002535357A (fr) |
AT (1) | ATE380548T1 (fr) |
AU (1) | AU3584200A (fr) |
CA (1) | CA2360671A1 (fr) |
DE (1) | DE60037394T2 (fr) |
IL (3) | IL144294A0 (fr) |
NZ (1) | NZ513487A (fr) |
WO (1) | WO2000044364A2 (fr) |
ZA (1) | ZA200105823B (fr) |
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ATE380548T1 (de) * | 1999-01-29 | 2007-12-15 | Univ Illinois | Verwendung von p53 inhibitoren zur behandlung von nebenerscheinungen bei der krebstherapie |
AU2001278875B2 (en) * | 2000-07-06 | 2007-06-07 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Tetrahydrobenzothiazole analogues as neuroprotective agents |
US6696441B1 (en) | 2000-08-11 | 2004-02-24 | The Regents Of The University Of California | Inhibition of p53-induced stress response |
AU2001294515A1 (en) * | 2000-08-11 | 2002-02-25 | The Regents Of The University Of California | Use of stat-6 inhibitors as therapeutic agents |
WO2002076439A2 (fr) * | 2001-03-23 | 2002-10-03 | The Board Of Trustees Of The University Of Illinois | Composes capables de moduler l'activite de transporteurs de medicaments multiples et leur utilisation therapeutique |
US7601846B2 (en) | 2001-06-26 | 2009-10-13 | The Regents Of The University Of California | Compounds having activity as inhibitors of apoptosis |
US20040198783A1 (en) * | 2003-04-03 | 2004-10-07 | Semafore Pharmaceuticals Inc. | Targeted bone marrow protection agents |
WO2004089345A1 (fr) * | 2003-04-03 | 2004-10-21 | Semafore Pharmaceuticals Inc. | Ciblage osseux de nanoparticules biodegradables contenant un medicament |
US7657893B2 (en) * | 2003-04-23 | 2010-02-02 | International Business Machines Corporation | Accounting method and logic for determining per-thread processor resource utilization in a simultaneous multi-threaded (SMT) processor |
US7132421B2 (en) * | 2003-06-17 | 2006-11-07 | Hoffmann-La Roche Inc. | CIS-imidazoles |
CA2536112A1 (fr) * | 2003-08-20 | 2005-03-03 | Northern Sydney And Central Coast Area Health Service | Methodes pouvant ameliorer la viabilite d'un embryon |
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-
2000
- 2000-01-28 AT AT00914455T patent/ATE380548T1/de not_active IP Right Cessation
- 2000-01-28 AU AU35842/00A patent/AU3584200A/en not_active Abandoned
- 2000-01-28 US US09/493,527 patent/US6593353B1/en not_active Expired - Lifetime
- 2000-01-28 DE DE60037394T patent/DE60037394T2/de not_active Expired - Lifetime
- 2000-01-28 WO PCT/US2000/002104 patent/WO2000044364A2/fr active Application Filing
- 2000-01-28 NZ NZ513487A patent/NZ513487A/xx unknown
- 2000-01-28 CA CA002360671A patent/CA2360671A1/fr not_active Abandoned
- 2000-01-28 EP EP00914455A patent/EP1143943B1/fr not_active Revoked
- 2000-01-28 JP JP2000595668A patent/JP2002535357A/ja active Pending
- 2000-01-28 IL IL14429400A patent/IL144294A0/xx unknown
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2001
- 2001-06-13 US US09/880,417 patent/US7012087B2/en not_active Expired - Lifetime
- 2001-07-12 IL IL144294A patent/IL144294A/en not_active IP Right Cessation
- 2001-07-16 ZA ZA200105823A patent/ZA200105823B/en unknown
- 2001-09-06 US US09/947,757 patent/US20020019425A1/en not_active Abandoned
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2003
- 2003-01-24 US US10/350,560 patent/US6982277B2/en not_active Expired - Lifetime
- 2003-01-28 US US10/352,597 patent/US7008956B2/en not_active Expired - Lifetime
-
2005
- 2005-05-24 US US11/136,231 patent/US20050222224A1/en not_active Abandoned
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2008
- 2008-01-30 US US12/022,317 patent/US20080161426A1/en not_active Abandoned
- 2008-12-04 IL IL195723A patent/IL195723A/en not_active IP Right Cessation
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Also Published As
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AU3584200A (en) | 2000-08-18 |
DE60037394T2 (de) | 2009-01-02 |
IL144294A (en) | 2010-04-15 |
CA2360671A1 (fr) | 2000-08-03 |
US20050222224A1 (en) | 2005-10-06 |
US20020006941A1 (en) | 2002-01-17 |
DE60037394D1 (de) | 2008-01-24 |
EP1143943A2 (fr) | 2001-10-17 |
ATE380548T1 (de) | 2007-12-15 |
NZ513487A (en) | 2003-02-28 |
WO2000044364A2 (fr) | 2000-08-03 |
US6593353B1 (en) | 2003-07-15 |
US7012087B2 (en) | 2006-03-14 |
US7008956B2 (en) | 2006-03-07 |
IL195723A (en) | 2010-12-30 |
JP2010265321A (ja) | 2010-11-25 |
IL144294A0 (en) | 2002-05-23 |
US20030144331A1 (en) | 2003-07-31 |
US20030176318A1 (en) | 2003-09-18 |
US20020019425A1 (en) | 2002-02-14 |
US20080161426A1 (en) | 2008-07-03 |
JP2002535357A (ja) | 2002-10-22 |
WO2000044364A3 (fr) | 2001-08-23 |
US6982277B2 (en) | 2006-01-03 |
EP1143943A3 (fr) | 2002-09-11 |
EP1143943B1 (fr) | 2007-12-12 |
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