ZA200105059B - Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications. - Google Patents
Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications. Download PDFInfo
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- ZA200105059B ZA200105059B ZA200105059A ZA200105059A ZA200105059B ZA 200105059 B ZA200105059 B ZA 200105059B ZA 200105059 A ZA200105059 A ZA 200105059A ZA 200105059 A ZA200105059 A ZA 200105059A ZA 200105059 B ZA200105059 B ZA 200105059B
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- South Africa
- Prior art keywords
- bile acid
- amount
- combination
- compound
- compounds
- Prior art date
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- RISCULYDRMPQKP-UHFFFAOYSA-M trimethyl-[6-(prop-2-enylamino)hexyl]azanium;chloride Chemical compound [Cl-].C[N+](C)(C)CCCCCCNCC=C RISCULYDRMPQKP-UHFFFAOYSA-M 0.000 description 1
- 230000003827 upregulation Effects 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11395598P | 1998-12-23 | 1998-12-23 |
Publications (1)
Publication Number | Publication Date |
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ZA200105059B true ZA200105059B (en) | 2002-06-20 |
Family
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Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200105060A ZA200105060B (en) | 1998-12-23 | 2001-06-20 | Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications. |
ZA200105062A ZA200105062B (en) | 1998-12-23 | 2001-06-20 | Combinations of ileal bile acid transport inhibitors and nicotinic acid derivatives for cardiovascular indications. |
ZA200105059A ZA200105059B (en) | 1998-12-23 | 2001-06-20 | Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications. |
ZA200105061A ZA200105061B (en) | 1998-12-23 | 2001-06-20 | Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications. |
ZA200105056A ZA200105056B (en) | 1998-12-23 | 2001-06-20 | Combinations for cardiovascular indications. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
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ZA200105060A ZA200105060B (en) | 1998-12-23 | 2001-06-20 | Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications. |
ZA200105062A ZA200105062B (en) | 1998-12-23 | 2001-06-20 | Combinations of ileal bile acid transport inhibitors and nicotinic acid derivatives for cardiovascular indications. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
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ZA200105061A ZA200105061B (en) | 1998-12-23 | 2001-06-20 | Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications. |
ZA200105056A ZA200105056B (en) | 1998-12-23 | 2001-06-20 | Combinations for cardiovascular indications. |
Country Status (23)
Country | Link |
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US (1) | US20040058908A1 (zh) |
EP (2) | EP1140187B1 (zh) |
JP (1) | JP2002533411A (zh) |
KR (1) | KR20020002367A (zh) |
CN (1) | CN1342091A (zh) |
AR (1) | AR037482A1 (zh) |
AT (1) | ATE248606T1 (zh) |
AU (1) | AU779264B2 (zh) |
BR (1) | BR9916564A (zh) |
CA (1) | CA2356515A1 (zh) |
CZ (1) | CZ20012344A3 (zh) |
DE (1) | DE69911058T2 (zh) |
DK (1) | DK1140187T3 (zh) |
EA (1) | EA200100704A1 (zh) |
ES (1) | ES2207330T3 (zh) |
HU (1) | HUP0104655A2 (zh) |
IL (1) | IL143944A0 (zh) |
MX (1) | MXPA01006468A (zh) |
NO (1) | NO20013157L (zh) |
NZ (1) | NZ512532A (zh) |
PT (1) | PT1140187E (zh) |
WO (1) | WO2000038725A1 (zh) |
ZA (5) | ZA200105060B (zh) |
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CN114761080A (zh) | 2019-12-04 | 2022-07-15 | 阿尔比里奥公司 | 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
CN114761018A (zh) | 2019-12-04 | 2022-07-15 | 阿尔比里奥公司 | 苯并硫杂二氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
JP2023537285A (ja) | 2020-08-03 | 2023-08-31 | アルビレオ・アクチボラグ | ベンゾチア(ジ)アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
JP2023549226A (ja) | 2020-11-12 | 2023-11-22 | アルビレオ エービー | 進行性家族性肝内胆汁うっ滞症(pfic)を処置するためのオデビキシバット |
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-
1999
- 1999-12-17 NZ NZ512532A patent/NZ512532A/en unknown
- 1999-12-17 PT PT99965901T patent/PT1140187E/pt unknown
- 1999-12-17 IL IL14394499A patent/IL143944A0/xx unknown
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- 1999-12-17 EA EA200100704A patent/EA200100704A1/ru unknown
- 1999-12-17 CN CN99816302A patent/CN1342091A/zh active Pending
- 1999-12-17 BR BR9916564-3A patent/BR9916564A/pt not_active IP Right Cessation
- 1999-12-17 CZ CZ20012344A patent/CZ20012344A3/cs unknown
- 1999-12-17 WO PCT/US1999/027946 patent/WO2000038725A1/en not_active Application Discontinuation
- 1999-12-17 CA CA002356515A patent/CA2356515A1/en not_active Abandoned
- 1999-12-17 DE DE69911058T patent/DE69911058T2/de not_active Expired - Fee Related
- 1999-12-17 AU AU21577/00A patent/AU779264B2/en not_active Ceased
- 1999-12-17 AT AT99965901T patent/ATE248606T1/de not_active IP Right Cessation
- 1999-12-17 DK DK99965901T patent/DK1140187T3/da active
- 1999-12-17 ES ES99965901T patent/ES2207330T3/es not_active Expired - Lifetime
- 1999-12-17 HU HU0104655A patent/HUP0104655A2/hu unknown
- 1999-12-17 EP EP19990965901 patent/EP1140187B1/en not_active Revoked
- 1999-12-17 EP EP03016600A patent/EP1354604A1/en not_active Withdrawn
- 1999-12-17 KR KR1020017008088A patent/KR20020002367A/ko not_active Application Discontinuation
- 1999-12-17 MX MXPA01006468A patent/MXPA01006468A/es unknown
- 1999-12-23 AR ARP990106756A patent/AR037482A1/es not_active Application Discontinuation
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2001
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2002
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AU779264B2 (en) | 2005-01-13 |
IL143944A0 (en) | 2002-04-21 |
EP1354604A1 (en) | 2003-10-22 |
CZ20012344A3 (cs) | 2002-01-16 |
NO20013157D0 (no) | 2001-06-22 |
WO2000038725A1 (en) | 2000-07-06 |
AU2157700A (en) | 2000-07-31 |
US20040058908A1 (en) | 2004-03-25 |
DK1140187T3 (da) | 2003-12-22 |
EA200100704A1 (ru) | 2002-02-28 |
CN1342091A (zh) | 2002-03-27 |
PT1140187E (pt) | 2004-01-30 |
DE69911058T2 (de) | 2004-06-03 |
BR9916564A (pt) | 2002-01-29 |
MXPA01006468A (es) | 2004-03-10 |
AR037482A1 (es) | 2004-11-17 |
CA2356515A1 (en) | 2000-07-06 |
ZA200105062B (en) | 2002-08-28 |
EP1140187B1 (en) | 2003-09-03 |
DE69911058D1 (de) | 2003-10-09 |
ZA200105060B (en) | 2002-09-20 |
NO20013157L (no) | 2001-08-22 |
EP1140187A1 (en) | 2001-10-10 |
HUP0104655A2 (hu) | 2002-04-29 |
ZA200105061B (en) | 2002-06-20 |
NZ512532A (en) | 2003-12-19 |
ZA200105056B (en) | 2002-06-20 |
ATE248606T1 (de) | 2003-09-15 |
JP2002533411A (ja) | 2002-10-08 |
KR20020002367A (ko) | 2002-01-09 |
ES2207330T3 (es) | 2004-05-16 |
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