ZA200007754B - Benzimidazole derivatives as modulators of IgE. - Google Patents

Benzimidazole derivatives as modulators of IgE. Download PDF

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Publication number
ZA200007754B
ZA200007754B ZA200007754A ZA200007754A ZA200007754B ZA 200007754 B ZA200007754 B ZA 200007754B ZA 200007754 A ZA200007754 A ZA 200007754A ZA 200007754 A ZA200007754 A ZA 200007754A ZA 200007754 B ZA200007754 B ZA 200007754B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical composition
substituted
clogp
mammal
treating
Prior art date
Application number
ZA200007754A
Other languages
English (en)
Inventor
Jagadish Sircar
Mark L Richards
Michael G Campbell
Michael W Major
Original Assignee
Avanir Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22198947&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200007754(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Avanir Pharmaceuticals filed Critical Avanir Pharmaceuticals
Publication of ZA200007754B publication Critical patent/ZA200007754B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Amplifiers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA200007754A 1998-05-22 2000-02-21 Benzimidazole derivatives as modulators of IgE. ZA200007754B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8649498P 1998-05-22 1998-05-22

Publications (1)

Publication Number Publication Date
ZA200007754B true ZA200007754B (en) 2001-08-16

Family

ID=22198947

Family Applications (3)

Application Number Title Priority Date Filing Date
ZA200007754A ZA200007754B (en) 1998-05-22 2000-02-21 Benzimidazole derivatives as modulators of IgE.
ZA200007752A ZA200007752B (en) 1998-05-22 2000-12-21 Compounds having IgE affecting properties.
ZA200007753A ZA200007753B (en) 1998-05-22 2000-12-21 Benzimidazole analogs as down-regulators of IgE.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ZA200007752A ZA200007752B (en) 1998-05-22 2000-12-21 Compounds having IgE affecting properties.
ZA200007753A ZA200007753B (en) 1998-05-22 2000-12-21 Benzimidazole analogs as down-regulators of IgE.

Country Status (22)

Country Link
US (2) US6271390B1 (cs)
EP (3) EP1077695A2 (cs)
JP (3) JP2002516277A (cs)
KR (1) KR100591652B1 (cs)
CN (4) CN1721411A (cs)
AT (1) ATE292465T1 (cs)
AU (3) AU4197899A (cs)
BR (3) BR9910640A (cs)
CA (3) CA2332985A1 (cs)
CZ (2) CZ20004351A3 (cs)
DE (1) DE69924607T2 (cs)
ES (1) ES2241285T3 (cs)
HU (3) HUP0102128A3 (cs)
IL (3) IL139828A0 (cs)
MX (3) MXPA00011422A (cs)
NO (3) NO20005889L (cs)
NZ (2) NZ508413A (cs)
PL (3) PL345219A1 (cs)
RU (2) RU2236221C2 (cs)
UA (2) UA67775C2 (cs)
WO (3) WO1999061013A2 (cs)
ZA (3) ZA200007754B (cs)

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Also Published As

Publication number Publication date
US6451829B2 (en) 2002-09-17
PL345560A1 (en) 2001-12-17
US20020010343A1 (en) 2002-01-24
UA67775C2 (uk) 2004-07-15
BR9910642A (pt) 2001-10-09
BR9910641A (pt) 2001-10-02
ATE292465T1 (de) 2005-04-15
CA2332999A1 (en) 1999-12-02
HUP0102128A3 (en) 2002-05-28
DE69924607D1 (de) 2005-05-12
NO20005889L (no) 2001-01-22
EP1077700B1 (en) 2005-04-06
ZA200007753B (en) 2001-07-18
CN1219510C (zh) 2005-09-21
AU754562B2 (en) 2002-11-21
PL345952A1 (en) 2002-01-14
WO1999061013A2 (en) 1999-12-02
IL139828A0 (en) 2002-02-10
CZ20004351A3 (cs) 2001-10-17
JP2002516274A (ja) 2002-06-04
ZA200007752B (en) 2001-12-05
NO20005888L (no) 2001-01-22
HUP0102550A2 (hu) 2001-10-28
RU2236221C2 (ru) 2004-09-20
NZ508413A (en) 2003-08-29
NO20005889D0 (no) 2000-11-21
CN1311679A (zh) 2001-09-05
NO20005887L (no) 2001-01-19
EP1079830A1 (en) 2001-03-07
NO20005887D0 (no) 2000-11-21
UA67774C2 (uk) 2004-07-15
AU754943B2 (en) 2002-11-28
JP2002516276A (ja) 2002-06-04
RU2236220C2 (ru) 2004-09-20
US6271390B1 (en) 2001-08-07
AU4094299A (en) 1999-12-13
WO1999061019A1 (en) 1999-12-02
WO1999061020A1 (en) 1999-12-02
NZ508416A (en) 2004-01-30
CZ20004350A3 (cs) 2002-02-13
HUP0102550A3 (en) 2002-11-28
CN1311675A (zh) 2001-09-05
MXPA00011422A (es) 2002-12-13
WO1999061013A3 (en) 2000-04-06
MXPA00011470A (es) 2002-10-17
CA2332985A1 (en) 1999-12-02
ES2241285T3 (es) 2005-10-16
HUP0101894A2 (hu) 2002-02-28
IL139826A0 (en) 2002-02-10
JP2002516277A (ja) 2002-06-04
EP1077695A2 (en) 2001-02-28
CN1721411A (zh) 2006-01-18
KR100591652B1 (ko) 2006-06-26
HUP0101894A3 (en) 2002-07-29
DE69924607T2 (de) 2006-02-02
PL345219A1 (en) 2001-12-03
KR20010030179A (ko) 2001-04-16
IL139827A0 (en) 2002-02-10
BR9910640A (pt) 2001-10-30
CA2332989A1 (en) 1999-12-02
AU4197899A (en) 1999-12-13
CN1317965A (zh) 2001-10-17
MXPA00011467A (es) 2002-10-17
EP1077700A1 (en) 2001-02-28
HUP0102128A2 (hu) 2002-03-28
NO20005888D0 (no) 2000-11-21
AU4312099A (en) 1999-12-13

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