YU71894A - Novi farmaceutski preparat sa difuziono-osmotskom kontrolom oslobađanja leka i postupak za dobivanje istog - Google Patents

Novi farmaceutski preparat sa difuziono-osmotskom kontrolom oslobađanja leka i postupak za dobivanje istog

Info

Publication number
YU71894A
YU71894A YU71894A YU71894A YU71894A YU 71894 A YU71894 A YU 71894A YU 71894 A YU71894 A YU 71894A YU 71894 A YU71894 A YU 71894A YU 71894 A YU71894 A YU 71894A
Authority
YU
Yugoslavia
Prior art keywords
hydrophilic polymer
layer
active agent
core
preparation
Prior art date
Application number
YU71894A
Other languages
English (en)
Inventor
R. Fekete
M. Kiraly
G. Sipos
Z. Jambor
G. Ujfalussy
M. Gora
I. Klebovich
S. Drabant
A. Mandi
G. Kiss
E. Barczay
M. Krisztian
Original Assignee
Egis Gyogyszergyar Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyogyszergyar Rt. filed Critical Egis Gyogyszergyar Rt.
Publication of YU71894A publication Critical patent/YU71894A/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

Pronalazak se odnosi na novi farmaceutski preparat sa difuziono-osmostki kontrolisanim oslobađanjem leka koji sadrži jednoslojno tabletno jezgro koje uključuje polimerni film-prevlaku, terapeutski aktivni agens i hidrofilni polimer; ako se želi dvoslojno tabletno jezgro koje uključuje aktivni agens i hidrofilni polimer u svom prvom sloju i hidrofilni polimer u drugom sloju; bar jedan otvor na delu film-prevlake u kontaktu sa jezgrom ili slojem jezgra koji sadrži aktivni agens; i, ako se želi, koji sadrži jedan ili više otvora na svom delu u kontaktu sa drugim slojem koji sadrži hidrofilni polimer, koji obuhvata amonijum metakrilat kopolimer kao materijal prevlake i hidroksipropil-metilcelulozu kao hidrofilni polimer. Preparat prema pronalasku je primenljiv za dobivanje tableta sa kontrolisanim oslobađanjem leka koje sadrže kao aktivne agense, npr. beta-drenergeske inhibitore (npr. propranolol), kalcijum-antagoniste (npr. nifedipin), angiotensinski konver-tazeenzim (ACE) inhibitore (npr. kaptopril); prazosin ili nitroglicerin svi koriSćeni u obolenjima srca i cirkulacije; vasodilatorno aktivne agense (npr. pentoksifilin), nesteroidne antiinfalamatorne agense (npr. naproksen), analegstke lekove (npr. morfin) i lekove koji deluju na centralni nervni sistem (npr. amitriptilin, buspiron). Pronalazak se dalje odnosi na postupak za dobivanje gorajih preprarata.
YU71894A 1993-12-09 1994-12-08 Novi farmaceutski preparat sa difuziono-osmotskom kontrolom oslobađanja leka i postupak za dobivanje istog YU71894A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9303504A HU213407B (en) 1993-12-09 1993-12-09 Process for producing tablet with diffusive-osmotic release

Publications (1)

Publication Number Publication Date
YU71894A true YU71894A (sh) 1997-03-07

Family

ID=10984230

Family Applications (1)

Application Number Title Priority Date Filing Date
YU71894A YU71894A (sh) 1993-12-09 1994-12-08 Novi farmaceutski preparat sa difuziono-osmotskom kontrolom oslobađanja leka i postupak za dobivanje istog

Country Status (21)

Country Link
US (1) US5543155A (sh)
EP (1) EP0662321B1 (sh)
JP (1) JPH07277957A (sh)
KR (1) KR950016714A (sh)
AT (1) ATE185693T1 (sh)
BE (1) BE1009867A3 (sh)
BG (1) BG61592B1 (sh)
CA (1) CA2137426A1 (sh)
CZ (1) CZ288014B6 (sh)
DE (1) DE69421263T2 (sh)
ES (1) ES2114423B1 (sh)
FR (1) FR2713484B1 (sh)
GR (1) GR1002349B (sh)
HR (1) HRP940979A2 (sh)
HU (1) HU213407B (sh)
IT (1) IT1271122B (sh)
PL (1) PL306181A1 (sh)
RU (1) RU2133605C1 (sh)
SK (1) SK279735B6 (sh)
UA (1) UA34458C2 (sh)
YU (1) YU71894A (sh)

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US6485748B1 (en) 1997-12-12 2002-11-26 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US20030153607A1 (en) * 1998-11-12 2003-08-14 Smithkline Beecham P.L.C. Novel composition and use
US20040102486A1 (en) * 1998-11-12 2004-05-27 Smithkline Beecham Corporation Novel method of treatment
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CA2354057C (en) 1998-12-11 2009-02-10 Nostrum Pharmaceuticals, Inc. Sustained release tablet containing hydrocolloid and cellulose ether
MXPA02006335A (es) 1999-12-23 2002-12-13 Pfizer Prod Inc Forma de dosificacion de farmaco en capas impulsada por hidrogel.
DE60038698T2 (de) * 1999-12-23 2009-05-07 Pfizer Products Inc., Groton Hydrogel-gesteuerte dosierungsform
US6753011B2 (en) 2000-01-14 2004-06-22 Osmotica Corp Combined diffusion/osmotic pumping drug delivery system
US6352721B1 (en) 2000-01-14 2002-03-05 Osmotica Corp. Combined diffusion/osmotic pumping drug delivery system
JP2003521507A (ja) 2000-02-04 2003-07-15 ディポメド，インコーポレイティド ゼロ次薬物放出に接近するシェル−コア剤形
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JP3887588B2 (ja) * 2002-08-30 2007-02-28 株式会社リガク Ｘ線回折による応力測定法
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Also Published As

Publication number Publication date
CA2137426A1 (en) 1995-06-10
UA34458C2 (uk) 2001-03-15
ES2114423A1 (es) 1998-05-16
EP0662321A1 (en) 1995-07-12
BG61592B1 (bg) 1998-01-30
IT1271122B (it) 1997-05-26
ITMI942484A0 (it) 1994-12-09
HUT69397A (en) 1995-09-28
JPH07277957A (ja) 1995-10-24
DE69421263D1 (de) 1999-11-25
RU2133605C1 (ru) 1999-07-27
CZ309994A3 (en) 1995-07-12
US5543155A (en) 1996-08-06
KR950016714A (ko) 1995-07-20
SK279735B6 (sk) 1999-03-12
FR2713484B1 (fr) 1997-12-12
SK152494A3 (en) 1995-07-11
ATE185693T1 (de) 1999-11-15
RU94043798A (ru) 1996-11-10
HU213407B (en) 1997-06-30
GR1002349B (el) 1996-05-29
BE1009867A3 (fr) 1997-10-07
ITMI942484A1 (it) 1996-06-09
CZ288014B6 (cs) 2001-04-11
HU9303504D0 (en) 1994-04-28
DE69421263T2 (de) 2000-05-11
PL306181A1 (en) 1995-06-12
FR2713484A1 (fr) 1995-06-16
EP0662321B1 (en) 1999-10-20
ES2114423B1 (es) 1999-07-01
BG99252A (en) 1995-09-29
HRP940979A2 (en) 1997-02-28

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