YU71894A - Novi farmaceutski preparat sa difuziono-osmotskom kontrolom oslobađanja leka i postupak za dobivanje istog - Google Patents

Novi farmaceutski preparat sa difuziono-osmotskom kontrolom oslobađanja leka i postupak za dobivanje istog

Info

Publication number
YU71894A
YU71894A YU71894A YU71894A YU71894A YU 71894 A YU71894 A YU 71894A YU 71894 A YU71894 A YU 71894A YU 71894 A YU71894 A YU 71894A YU 71894 A YU71894 A YU 71894A
Authority
YU
Yugoslavia
Prior art keywords
hydrophilic polymer
layer
active agent
core
preparation
Prior art date
Application number
YU71894A
Other languages
English (en)
Inventor
R. Fekete
M. Kiraly
G. Sipos
Z. Jambor
G. Ujfalussy
M. Gora
I. Klebovich
S. Drabant
A. Mandi
G. Kiss
E. Barczay
M. Krisztian
Original Assignee
Egis Gyogyszergyar Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyogyszergyar Rt. filed Critical Egis Gyogyszergyar Rt.
Publication of YU71894A publication Critical patent/YU71894A/sh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

Pronalazak se odnosi na novi farmaceutski preparat sa difuziono-osmostki kontrolisanim oslobađanjem leka koji sadrži jednoslojno tabletno jezgro koje uključuje polimerni film-prevlaku, terapeutski aktivni agens i hidrofilni polimer; ako se želi dvoslojno tabletno jezgro koje uključuje aktivni agens i hidrofilni polimer u svom prvom sloju i hidrofilni polimer u drugom sloju; bar jedan otvor na delu film-prevlake u kontaktu sa jezgrom ili slojem jezgra koji sadrži aktivni agens; i, ako se želi, koji sadrži jedan ili više otvora na svom delu u kontaktu sa drugim slojem koji sadrži hidrofilni polimer, koji obuhvata amonijum metakrilat kopolimer kao materijal prevlake i hidroksipropil-metilcelulozu kao hidrofilni polimer. Preparat prema pronalasku je primenljiv za dobivanje tableta sa kontrolisanim oslobađanjem leka koje sadrže kao aktivne agense, npr. beta-drenergeske inhibitore (npr. propranolol), kalcijum-antagoniste (npr. nifedipin), angiotensinski konver-tazeenzim (ACE) inhibitore (npr. kaptopril); prazosin ili nitroglicerin svi koriSćeni u obolenjima srca i cirkulacije; vasodilatorno aktivne agense (npr. pentoksifilin), nesteroidne antiinfalamatorne agense (npr. naproksen), analegstke lekove (npr. morfin) i lekove koji deluju na centralni nervni sistem (npr. amitriptilin, buspiron). Pronalazak se dalje odnosi na postupak za dobivanje gorajih preprarata.
YU71894A 1993-12-09 1994-12-08 Novi farmaceutski preparat sa difuziono-osmotskom kontrolom oslobađanja leka i postupak za dobivanje istog YU71894A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9303504A HU213407B (en) 1993-12-09 1993-12-09 Process for producing tablet with diffusive-osmotic release

Publications (1)

Publication Number Publication Date
YU71894A true YU71894A (sh) 1997-03-07

Family

ID=10984230

Family Applications (1)

Application Number Title Priority Date Filing Date
YU71894A YU71894A (sh) 1993-12-09 1994-12-08 Novi farmaceutski preparat sa difuziono-osmotskom kontrolom oslobađanja leka i postupak za dobivanje istog

Country Status (21)

Country Link
US (1) US5543155A (sh)
EP (1) EP0662321B1 (sh)
JP (1) JPH07277957A (sh)
KR (1) KR950016714A (sh)
AT (1) ATE185693T1 (sh)
BE (1) BE1009867A3 (sh)
BG (1) BG61592B1 (sh)
CA (1) CA2137426A1 (sh)
CZ (1) CZ288014B6 (sh)
DE (1) DE69421263T2 (sh)
ES (1) ES2114423B1 (sh)
FR (1) FR2713484B1 (sh)
GR (1) GR1002349B (sh)
HR (1) HRP940979A2 (sh)
HU (1) HU213407B (sh)
IT (1) IT1271122B (sh)
PL (1) PL306181A1 (sh)
RU (1) RU2133605C1 (sh)
SK (1) SK279735B6 (sh)
UA (1) UA34458C2 (sh)
YU (1) YU71894A (sh)

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US6485748B1 (en) 1997-12-12 2002-11-26 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US20040081697A1 (en) * 1998-11-12 2004-04-29 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
US20040102486A1 (en) * 1998-11-12 2004-05-27 Smithkline Beecham Corporation Novel method of treatment
US20030153607A1 (en) * 1998-11-12 2003-08-14 Smithkline Beecham P.L.C. Novel composition and use
US6416786B1 (en) 1998-12-11 2002-07-09 Nostrum Pharmaceuticals, Inc. Sustained release tablet containing hydrocolloid and cellulose ether
BR0016707A (pt) 1999-12-23 2002-09-03 Pfizer Prod Inc Forma de dosagem de droga em camadas acionada por hidrogel
EE200200361A (et) * 1999-12-23 2003-10-15 Pfizer Products Inc. Hüdrogeeli-juhitav ravimi doseerimise vahend
US6753011B2 (en) 2000-01-14 2004-06-22 Osmotica Corp Combined diffusion/osmotic pumping drug delivery system
US6352721B1 (en) * 2000-01-14 2002-03-05 Osmotica Corp. Combined diffusion/osmotic pumping drug delivery system
JP2003521507A (ja) 2000-02-04 2003-07-15 ディポメド,インコーポレイティド ゼロ次薬物放出に接近するシェル−コア剤形
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US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
CA2359812C (en) * 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
US20040062787A1 (en) * 2001-12-17 2004-04-01 Daley William Lionel Therapeutic combination of amlodipineand benazepril/benazeprilat
US6419903B1 (en) * 2001-08-20 2002-07-16 Colgate Palmolive Company Breath freshening film
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TW200302748A (en) * 2002-02-01 2003-08-16 Pfizer Prod Inc Osmotic delivery system
US7125563B2 (en) * 2002-04-12 2006-10-24 Dava Pharmaceuticals, Inc. Sustained release pharmaceutical preparations and methods for producing the same
JP3887588B2 (ja) * 2002-08-30 2007-02-28 株式会社リガク X線回折による応力測定法
AR045330A1 (es) * 2003-08-07 2005-10-26 Sb Pharmco Inc Forma de dosificacion oral, procedimiento para su preparacion y uso del compuesto 5-(4-(2-(n-metil-n- (2-piridil)amino)etoxi )bencil) tiazolidin-2,4-diona o una sal o solvato farmaceuticamente aceptable del mismo para prepararla
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Also Published As

Publication number Publication date
BG99252A (en) 1995-09-29
FR2713484B1 (fr) 1997-12-12
IT1271122B (it) 1997-05-26
JPH07277957A (ja) 1995-10-24
RU2133605C1 (ru) 1999-07-27
CZ309994A3 (en) 1995-07-12
US5543155A (en) 1996-08-06
RU94043798A (ru) 1996-11-10
PL306181A1 (en) 1995-06-12
DE69421263D1 (de) 1999-11-25
UA34458C2 (uk) 2001-03-15
DE69421263T2 (de) 2000-05-11
ITMI942484A1 (it) 1996-06-09
ITMI942484A0 (it) 1994-12-09
CA2137426A1 (en) 1995-06-10
SK279735B6 (sk) 1999-03-12
ES2114423A1 (es) 1998-05-16
CZ288014B6 (cs) 2001-04-11
FR2713484A1 (fr) 1995-06-16
HU9303504D0 (en) 1994-04-28
HU213407B (en) 1997-06-30
SK152494A3 (en) 1995-07-11
EP0662321B1 (en) 1999-10-20
HRP940979A2 (en) 1997-02-28
GR1002349B (el) 1996-05-29
BG61592B1 (bg) 1998-01-30
ES2114423B1 (es) 1999-07-01
HUT69397A (en) 1995-09-28
KR950016714A (ko) 1995-07-20
EP0662321A1 (en) 1995-07-12
BE1009867A3 (fr) 1997-10-07
ATE185693T1 (de) 1999-11-15

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