YU71195A - Prečišćeni proteini papilomavirusa - Google Patents

Prečišćeni proteini papilomavirusa

Info

Publication number
YU71195A
YU71195A YU71195A YU71195A YU71195A YU 71195 A YU71195 A YU 71195A YU 71195 A YU71195 A YU 71195A YU 71195 A YU71195 A YU 71195A YU 71195 A YU71195 A YU 71195A
Authority
YU
Yugoslavia
Prior art keywords
purified
papilloma virus
protein
virus proteins
yeast host
Prior art date
Application number
YU71195A
Other languages
English (en)
Inventor
Ernest D. Lehman
James C. Cook Iii
George A. Hugh
Kathryn J. Hofmann
Kathrin U. Jansen
Joseph G. Joyce
Henry Z. Markus
Loren D. Schultz
Original Assignee
Merck And Co.Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck And Co.Inc. filed Critical Merck And Co.Inc.
Publication of YU71195A publication Critical patent/YU71195A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Prečišćeni papilomavirus protein se dobija transformisanjem ćelije domaćina kvasca sa genom koji kodira bilo L1 ili L1 u kombinaciji sa L2 proteinom, kultivisanjem ćelija domaćina kvasca, i prečišćavanjem ekspresionisanog proteina koristeći najmanje jedan hromatografski stupanj. Prečišćeni protein je najmanje 70% čist.
YU71195A 1994-11-14 1995-11-14 Prečišćeni proteini papilomavirusa YU71195A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33936894A 1994-11-14 1994-11-14

Publications (1)

Publication Number Publication Date
YU71195A true YU71195A (sh) 1999-06-15

Family

ID=23328696

Family Applications (1)

Application Number Title Priority Date Filing Date
YU71195A YU71195A (sh) 1994-11-14 1995-11-14 Prečišćeni proteini papilomavirusa

Country Status (23)

Country Link
EP (1) EP0789767B1 (sh)
JP (1) JPH11500002A (sh)
KR (1) KR987000420A (sh)
CN (1) CN1173203A (sh)
AR (1) AR004464A1 (sh)
AT (1) ATE245192T1 (sh)
AU (1) AU708737B2 (sh)
BR (1) BR9510520A (sh)
CZ (1) CZ145297A3 (sh)
DE (1) DE69531308T2 (sh)
DK (1) DK0789767T3 (sh)
ES (1) ES2201129T3 (sh)
FI (1) FI972030A (sh)
HR (1) HRP950557A2 (sh)
HU (1) HUT77559A (sh)
MX (1) MX9703570A (sh)
NZ (1) NZ298224A (sh)
PT (1) PT789767E (sh)
RU (1) RU2161651C2 (sh)
SK (1) SK281878B6 (sh)
UA (1) UA35639C2 (sh)
WO (1) WO1996015247A1 (sh)
YU (1) YU71195A (sh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153201A (en) * 1993-03-09 2000-11-28 University Of Rochester Oral immunization with papillomavirus virus-like particles
WO1996009375A1 (en) * 1994-09-22 1996-03-28 Merck & Co., Inc. Dna encoding human papillomavirus type 6a
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
EP0973546B1 (en) * 1997-04-08 2004-03-17 Merck & Co., Inc. Stabilized human papillomavirus formulations
IL141130A0 (en) * 1998-08-14 2002-02-10 Merck & Co Inc Process for purifying human papilloma virus-like particles
AUPP765398A0 (en) 1998-12-11 1999-01-14 University Of Queensland, The Treatment of papillomavirus infections
AU764138B2 (en) 1999-02-05 2003-08-14 Merck Sharp & Dohme Corp. Human papilloma virus vaccine formulations
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
EP1501921B2 (en) 2002-04-30 2012-07-25 Oncolytics Biotech Inc. Improved viral purification methods
MY140664A (en) 2003-09-29 2010-01-15 Merck Sharp & Dohme Optimized expression of hpv 45 l1 in yeast
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
ES2559421T3 (es) * 2007-03-14 2016-02-12 Takeda Vaccines, Inc. Purificación de partículas similares a virus
EP2444103B1 (en) * 2009-06-19 2017-12-20 Eyegene Inc. Vaccine for cervical cancer
JOP20130186B1 (ar) 2012-06-22 2021-08-17 Takeda Vaccines Montana Inc تنقية الجزيئات الشبيهة بالفيروسات
CN103936840B (zh) * 2013-01-18 2019-04-09 北京康乐卫士生物技术股份有限公司 重组的人乳头瘤病毒33型l1蛋白及其用途
CN113278064B (zh) * 2021-07-20 2021-11-02 山东信得科技股份有限公司 一种用于胚毒类抗原净化处理的方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0595935T3 (da) * 1991-07-19 2003-07-21 Csl Ltd Papillomavirusvaccine
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
ATE492289T1 (de) * 1993-03-09 2011-01-15 Univ Rochester Herstellung von menschlichen papillomavirus hbv- 11 kapsidprotein l1 und virus-ähnliche partikeln
HUT76354A (en) * 1994-05-16 1997-08-28 Merck & Co Inc Papillomavirus vaccines

Also Published As

Publication number Publication date
KR987000420A (ko) 1998-03-30
NZ298224A (en) 1999-05-28
BR9510520A (pt) 1998-07-14
CN1173203A (zh) 1998-02-11
HRP950557A2 (en) 1997-08-31
EP0789767B1 (en) 2003-07-16
JPH11500002A (ja) 1999-01-06
WO1996015247A1 (en) 1996-05-23
UA35639C2 (uk) 2001-04-16
SK281878B6 (sk) 2001-08-06
DE69531308D1 (de) 2003-08-21
AR004464A1 (es) 1998-12-16
CZ145297A3 (en) 1997-10-15
ES2201129T3 (es) 2004-03-16
PT789767E (pt) 2003-11-28
RU2161651C2 (ru) 2001-01-10
MX9703570A (es) 1997-08-30
AU4365896A (en) 1996-06-06
HUT77559A (hu) 1998-06-29
DE69531308T2 (de) 2004-04-15
FI972030A0 (fi) 1997-05-13
SK59497A3 (en) 1998-03-04
EP0789767A1 (en) 1997-08-20
DK0789767T3 (da) 2003-10-20
AU708737B2 (en) 1999-08-12
FI972030A (fi) 1997-05-13
ATE245192T1 (de) 2003-08-15

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