HUP0104794A2 - Eljárás vírusrészecskék elkülönítésére - Google Patents

Eljárás vírusrészecskék elkülönítésére

Info

Publication number
HUP0104794A2
HUP0104794A2 HU0104794A HUP0104794A HUP0104794A2 HU P0104794 A2 HUP0104794 A2 HU P0104794A2 HU 0104794 A HU0104794 A HU 0104794A HU P0104794 A HUP0104794 A HU P0104794A HU P0104794 A2 HUP0104794 A2 HU P0104794A2
Authority
HU
Hungary
Prior art keywords
viral particles
separating viral
separating
sadenoviruses
fringed
Prior art date
Application number
HU0104794A
Other languages
English (en)
Inventor
Anne Barbot
Francis Blanche
Béatrice Cameron
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9816737A external-priority patent/FR2788064B1/fr
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HUP0104794A2 publication Critical patent/HUP0104794A2/hu
Publication of HUP0104794A3 publication Critical patent/HUP0104794A3/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351Methods of production or purification of viral material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01DNA viruses
    • G01N2333/075Adenoviridae
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A tal lm ny t rgya egy új elj r s vírusrészecskéknek biológiaik"zegből kiinduló elkül"nítésére és mennyiségi meghat roz s ra. Az eljr s legal bb egy kromatogr fi s lépést tartalmaz, ebben olyan hordozótalkalmaznak, amely egy m trixot és arra flexibilis oldall ncokkal rojtott ioncserélő csoportokat tartalmaz. A tal lm ny szerinti elj r sadenovírusok kül"nb"ző szerotípusainak azonosít s ra is alkalmazható. Ó
HU0104794A 1998-12-31 1999-12-30 Method for separating viral particles HUP0104794A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9816737A FR2788064B1 (fr) 1998-12-31 1998-12-31 Methode de separation de particules virales
US11994899P 1999-02-12 1999-02-12
PCT/FR1999/003315 WO2000040702A1 (fr) 1998-12-31 1999-12-30 Methode de separation de particules virales

Publications (2)

Publication Number Publication Date
HUP0104794A2 true HUP0104794A2 (hu) 2002-04-29
HUP0104794A3 HUP0104794A3 (en) 2006-03-28

Family

ID=26234748

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104794A HUP0104794A3 (en) 1998-12-31 1999-12-30 Method for separating viral particles

Country Status (15)

Country Link
US (2) US6537793B2 (hu)
EP (1) EP1141249A1 (hu)
JP (1) JP2003523169A (hu)
KR (1) KR100762033B1 (hu)
CN (1) CN1195057C (hu)
AU (1) AU779267B2 (hu)
BR (1) BR9916654A (hu)
CA (1) CA2356373A1 (hu)
CZ (1) CZ20012428A3 (hu)
HU (1) HUP0104794A3 (hu)
IL (2) IL143381A0 (hu)
NO (1) NO20013271L (hu)
NZ (1) NZ512504A (hu)
PL (1) PL349074A1 (hu)
WO (1) WO2000040702A1 (hu)

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US6689600B1 (en) 1998-11-16 2004-02-10 Introgen Therapeutics, Inc. Formulation of adenovirus for gene therapy
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US6447995B1 (en) 2000-10-04 2002-09-10 Genvec, Inc. Utilizing intrinsic fluorescence to detect adenovirus
US20030224354A1 (en) * 2002-05-30 2003-12-04 Introgen Therapeutics Inc. Quantifying viral particles with intrinsic fluorescence
EP1371723A1 (en) * 2002-06-12 2003-12-17 Procorde GmbH Process for preparing an adenovirus-containing preparation
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PL2350268T3 (pl) * 2008-11-03 2015-05-29 Crucell Holland Bv Sposób wytwarzania wektorów adenowirusowych
JP5716297B2 (ja) * 2009-06-25 2015-05-13 Jnc株式会社 クロマトグラフィー用充填剤、その製造方法、およびそれを用いたウイルス用ワクチンの製造方法
CN102573903B (zh) 2009-08-07 2015-12-02 特兰斯吉恩股份有限公司 用于治疗hbv感染的组合物
PL2488635T3 (pl) * 2009-10-15 2014-04-30 Crucell Holland Bv Proces do oczyszczania adenowirusa z hodowli o dużej gęstości komórek
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CN104968403A (zh) 2012-09-17 2015-10-07 格雷斯公司 色谱介质和装置
CN109134640A (zh) 2012-10-23 2019-01-04 爱默蕾大学 Gm-csf和il-4轭合物、组合物以及与其相关的方法
WO2015168383A1 (en) 2014-05-02 2015-11-05 W. R. Grace & Co.-Conn. Functionalized support material and methods of making and using functionalized support material
CN106794389A (zh) 2014-09-02 2017-05-31 Emd密理博公司 具有纳米原纤化表面特征的高表面积纤维介质
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WO2016131945A1 (en) 2015-02-20 2016-08-25 Transgene Sa Combination product with autophagy modulator
KR102566292B1 (ko) 2015-06-05 2023-08-10 더블유.알. 그레이스 앤드 캄파니-콘. 흡착성 바이오프로세싱 정화제와 이의 제조 및 사용 방법
EP3452081A1 (en) 2016-05-04 2019-03-13 Transgene SA Combination therapy with cpg tlr9 ligand
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GB201820806D0 (en) * 2018-12-20 2019-02-06 Ge Healthcare Bioprocess R&D Ab Large pore agarose
CN115326937B (zh) * 2021-05-11 2024-06-18 山东省食品药品检验研究院 一种基因毒杂质捕捉用固相探针及其使用方法与应用
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CN116768985B (zh) * 2022-12-07 2024-03-22 华北制药金坦生物技术股份有限公司 一种有效纯化病毒样颗粒的方法

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JP2003523169A (ja) * 1998-12-31 2003-08-05 アバンテイス・フアルマ・エス・アー ウイルス粒子の分離法

Also Published As

Publication number Publication date
NZ512504A (en) 2004-01-30
BR9916654A (pt) 2002-01-15
NO20013271D0 (no) 2001-06-29
JP2003523169A (ja) 2003-08-05
NO20013271L (no) 2001-08-28
CN1332796A (zh) 2002-01-23
US20020037565A1 (en) 2002-03-28
AU779267B2 (en) 2005-01-13
IL143381A (en) 2006-08-01
AU3049300A (en) 2000-07-24
CA2356373A1 (fr) 2000-07-13
WO2000040702A1 (fr) 2000-07-13
US20030170710A1 (en) 2003-09-11
US6537793B2 (en) 2003-03-25
EP1141249A1 (fr) 2001-10-10
CN1195057C (zh) 2005-03-30
HUP0104794A3 (en) 2006-03-28
IL143381A0 (en) 2002-04-21
CZ20012428A3 (cs) 2001-11-14
KR20020044106A (ko) 2002-06-14
KR100762033B1 (ko) 2007-10-04
PL349074A1 (en) 2002-07-01

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