YU66895A - Nova heterociklična jedinjenja, postupci za njihovo dibijanje i primena tih novih jedinjenja - Google Patents
Nova heterociklična jedinjenja, postupci za njihovo dibijanje i primena tih novih jedinjenjaInfo
- Publication number
- YU66895A YU66895A YU66895A YU66895A YU66895A YU 66895 A YU66895 A YU 66895A YU 66895 A YU66895 A YU 66895A YU 66895 A YU66895 A YU 66895A YU 66895 A YU66895 A YU 66895A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- preparation
- heterocyclic compounds
- new heterocyclic
- het
- compounds
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Opisana su nova hetoriciklična jedninjenja formule (I) u kojoj W predstavlja kiseonik ili sumpor, R je vodonik, halogen, amino grupa ili C3-10-cikloalkil, G je nezasićen het-1 do het-7, i r je 0,1 ili Z. Takodje je opisan postupak za dobijanje ovih jedinjenja i farmaceutske kompozicije koje ih sadrže, a koje se koriste kao stimulansi spoznajne funkcije predmozga i hipokampusa sisara, naročito u tretiranju Alzhajmerove bolesti.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32776694A | 1994-10-24 | 1994-10-24 | |
US44367395A | 1995-06-01 | 1995-06-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU66895A true YU66895A (sh) | 1998-09-18 |
Family
ID=26986055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU66895A YU66895A (sh) | 1994-10-24 | 1995-10-23 | Nova heterociklična jedinjenja, postupci za njihovo dibijanje i primena tih novih jedinjenja |
Country Status (21)
Country | Link |
---|---|
US (6) | US5672709A (sh) |
EP (1) | EP0709381A1 (sh) |
JP (1) | JPH08225575A (sh) |
KR (1) | KR960014125A (sh) |
CN (1) | CN1048986C (sh) |
AU (1) | AU705047B2 (sh) |
BR (1) | BR9504509A (sh) |
CA (1) | CA2161176A1 (sh) |
CO (1) | CO4480103A1 (sh) |
CZ (1) | CZ275995A3 (sh) |
FI (1) | FI955051A (sh) |
HU (1) | HUT76347A (sh) |
IL (1) | IL115717A0 (sh) |
NO (1) | NO306949B1 (sh) |
NZ (1) | NZ280300A (sh) |
PE (1) | PE12697A1 (sh) |
PL (1) | PL311077A1 (sh) |
RU (1) | RU2158262C2 (sh) |
TR (1) | TR199501305A2 (sh) |
TW (1) | TW420680B (sh) |
YU (1) | YU66895A (sh) |
Families Citing this family (42)
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US5998404A (en) * | 1994-10-24 | 1999-12-07 | Eli Lilly And Company | Heterocyclic compounds and their use |
US6040442A (en) * | 1995-06-01 | 2000-03-21 | Eli Lilly And Company | Process for preparing 1,2,5-thiadiazole containing ethers |
US5767280A (en) * | 1995-06-01 | 1998-06-16 | Eli Lilly And Company | Process for making heterocyclic compounds |
US5852037A (en) * | 1995-11-13 | 1998-12-22 | Eli Lilly And Company | Method for treating anxiety |
WO1997020819A1 (en) * | 1995-12-06 | 1997-06-12 | Eli Lilly And Company | Composition for treating pain |
EP0888355A1 (en) * | 1996-03-19 | 1999-01-07 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
US5914338A (en) * | 1996-04-02 | 1999-06-22 | Novo Nordisk | Heterocyclic compounds and their preparation and use |
JP2000509042A (ja) * | 1996-04-23 | 2000-07-18 | イーライ・リリー・アンド・カンパニー | ヘテロサイクリック化合物群 |
EP0900218B1 (en) * | 1996-04-23 | 2002-07-24 | Eli Lilly And Company | Heterocyclic compounds |
AU2738397A (en) * | 1996-04-23 | 1997-11-12 | Eli Lilly And Company | Heterocyclic compounds |
JP2000509045A (ja) * | 1996-04-23 | 2000-07-18 | イーライ・リリー・アンド・カンパニー | 複素環式化合物 |
EP0900217A4 (en) * | 1996-04-23 | 2001-05-23 | Lilly Co Eli | HETEROCYCLIC COMPOUNDS |
US6069159A (en) * | 1996-05-10 | 2000-05-30 | Eli Lilly And Company | Heterocyclic compounds |
DE69710526T2 (de) * | 1996-08-01 | 2002-10-02 | Eli Lilly And Co., Indianapolis | Verwendung von 3-(4-Hexyloxy-1,2,5-Thiadiazol-3-yl)-1,2,5,6-Tetrahydro-1-Methylpyridin (Xanomelin) zur Behandlung von bipolaren Störungen |
AU7871498A (en) * | 1996-12-20 | 1998-07-17 | Novo Nordisk A/S | A method of treating hypercholesterolemia and related disorders |
US6528529B1 (en) | 1998-03-31 | 2003-03-04 | Acadia Pharmaceuticals Inc. | Compounds with activity on muscarinic receptors |
US6620940B1 (en) | 1998-08-20 | 2003-09-16 | Eli Lilly And Company | Palladium-catalyzed cross-coupling chemistry on 3-chloro-4-halo-1,2,5-thiadiazole |
AU5123200A (en) | 1999-06-04 | 2000-12-28 | Eli Lilly And Company | 7-oxo-2-azabicyclo(2.2.1)heptanes as selective muscarinic receptor antagonist |
US6392329B1 (en) * | 1999-10-12 | 2002-05-21 | Face International Corp. | Piezoelectric vibrating apparatus |
CA2493245A1 (en) * | 2002-08-14 | 2004-02-26 | Neurosearch A/S | Novel quinuclidine derivatives and their use |
EA008767B1 (ru) * | 2002-10-08 | 2007-08-31 | Зе Скрипс Ресеч Инститьют | Ингибиторы гидролазы амидов жирных кислот |
US20070021404A1 (en) * | 2003-06-24 | 2007-01-25 | Dan Peters | Novel aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
DE602004031124D1 (de) * | 2003-08-13 | 2011-03-03 | Neurosearch As | Neue chinuklidinderivative und deren pharmazeutische verwendung |
US7309699B2 (en) | 2003-12-22 | 2007-12-18 | Abbott Laboratories | 3-Quinuclidinyl amino-substituted biaryl derivatives |
US20050137203A1 (en) * | 2003-12-22 | 2005-06-23 | Jianguo Ji | 3-quinuclidinyl amino-substituted biaryl derivatives |
US7241773B2 (en) | 2003-12-22 | 2007-07-10 | Abbott Laboratories | 3-quinuclidinyl heteroatom bridged biaryl derivatives |
US20050137398A1 (en) * | 2003-12-22 | 2005-06-23 | Jianguo Ji | 3-Quinuclidinyl heteroatom bridged biaryl derivatives |
DE602005015682D1 (de) * | 2004-02-04 | 2009-09-10 | Neurosearch As | Dimere azacyclische verbindungen und deren verwendung |
EP1831220A2 (en) * | 2004-12-20 | 2007-09-12 | Eli Lilly & Company | Processes for the preparation of 3,4-substituted-1,2,5-thiadiazoles and intermediates thereof |
EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
EP2275095A3 (en) * | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
US7849599B2 (en) * | 2006-09-28 | 2010-12-14 | Hydril Usa Manufacturing Llc | Imputing strength gradient in pressure vessels |
US20080078081A1 (en) * | 2006-09-28 | 2008-04-03 | Huff Philip A | High pressure-rated ram blowout preventer and method of manufacture |
US7721401B2 (en) * | 2006-09-28 | 2010-05-25 | Hydril Usa Manufacturing Llc | Reinforcement of irregular pressure vessels |
US20080105341A1 (en) * | 2006-11-02 | 2008-05-08 | Huff Philip A | Heat treatment of inlaid pressure vessels |
US20080105340A1 (en) * | 2006-11-02 | 2008-05-08 | Huff Philip A | Heat Treatment Method of Inlaid Pressure Vessels |
US8314119B2 (en) | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
AU2008326360A1 (en) * | 2007-11-21 | 2009-05-28 | Abbott Laboratories | Biaryl substituted azabicyclic alkane derivatives as nicotinic acetylcholine receptor activity modulators |
SG188307A1 (en) | 2010-09-23 | 2013-04-30 | Abbvie Inc | Monohydrate of an azaadamantane derivative |
JP2015506371A (ja) * | 2012-01-25 | 2015-03-02 | デメルクス,インコーポレイテッド | (1r,4r)7−オキソ−2−アザビシクロ[2.2.2]オクタ−5−エンおよびその誘導体 |
ES2770113T3 (es) | 2015-07-02 | 2020-06-30 | Horizon Orphan Llc | Análogos de la cisteamina resistentes a la ADO y sus usos |
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ES2111197T3 (es) * | 1993-04-21 | 1998-03-01 | Tosoh Corp | 3,4-dioxi-1,2,5-tiadiazoles en parte utiles como fungicidas. |
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DE69430816T2 (de) * | 1993-08-19 | 2002-12-19 | Novo Nordisk A/S, Bagsvaerd | Verwendung von Piperidin-Derivaten in der Behandlung von Schizophrenie |
-
1995
- 1995-06-06 US US08/470,789 patent/US5672709A/en not_active Expired - Fee Related
- 1995-06-06 US US08/470,787 patent/US5821370A/en not_active Expired - Fee Related
- 1995-06-06 US US08/470,791 patent/US5665745A/en not_active Expired - Lifetime
- 1995-06-06 US US08/470,790 patent/US5929247A/en not_active Expired - Fee Related
- 1995-06-06 US US08/468,481 patent/US5646289A/en not_active Expired - Fee Related
- 1995-06-06 US US08/470,788 patent/US5821371A/en not_active Expired - Fee Related
- 1995-10-20 HU HU9503045A patent/HUT76347A/hu unknown
- 1995-10-20 NZ NZ280300A patent/NZ280300A/en unknown
- 1995-10-23 AU AU34396/95A patent/AU705047B2/en not_active Ceased
- 1995-10-23 RU RU95118133/04A patent/RU2158262C2/ru active
- 1995-10-23 FI FI955051A patent/FI955051A/fi unknown
- 1995-10-23 NO NO954239A patent/NO306949B1/no not_active IP Right Cessation
- 1995-10-23 PE PE1995282695A patent/PE12697A1/es not_active Application Discontinuation
- 1995-10-23 EP EP95307513A patent/EP0709381A1/en not_active Withdrawn
- 1995-10-23 IL IL11571795A patent/IL115717A0/xx unknown
- 1995-10-23 KR KR1019950036595A patent/KR960014125A/ko active IP Right Grant
- 1995-10-23 CN CN95120382A patent/CN1048986C/zh not_active Expired - Fee Related
- 1995-10-23 YU YU66895A patent/YU66895A/sh unknown
- 1995-10-23 CO CO95049689A patent/CO4480103A1/es unknown
- 1995-10-23 BR BR9504509A patent/BR9504509A/pt not_active Application Discontinuation
- 1995-10-23 CZ CZ952759A patent/CZ275995A3/cs unknown
- 1995-10-23 CA CA002161176A patent/CA2161176A1/en not_active Abandoned
- 1995-10-23 JP JP7274104A patent/JPH08225575A/ja not_active Withdrawn
- 1995-10-23 PL PL95311077A patent/PL311077A1/xx unknown
- 1995-10-24 TR TR95/01305A patent/TR199501305A2/xx unknown
- 1995-10-27 TW TW084111356A patent/TW420680B/zh active
Also Published As
Publication number | Publication date |
---|---|
TW420680B (en) | 2001-02-01 |
JPH08225575A (ja) | 1996-09-03 |
HUT76347A (en) | 1997-08-28 |
CN1048986C (zh) | 2000-02-02 |
FI955051A (fi) | 1996-04-25 |
AU3439695A (en) | 1996-05-02 |
NO306949B1 (no) | 2000-01-17 |
PE12697A1 (es) | 1997-04-24 |
CN1145364A (zh) | 1997-03-19 |
CA2161176A1 (en) | 1996-04-25 |
CZ275995A3 (en) | 1996-08-14 |
EP0709381A1 (en) | 1996-05-01 |
PL311077A1 (en) | 1996-04-29 |
US5821370A (en) | 1998-10-13 |
NO954239L (no) | 1996-04-25 |
AU705047B2 (en) | 1999-05-13 |
BR9504509A (pt) | 1997-05-27 |
IL115717A0 (en) | 1996-01-19 |
KR960014125A (ko) | 1996-05-22 |
RU2158262C2 (ru) | 2000-10-27 |
TR199501305A2 (tr) | 1996-06-21 |
FI955051A0 (fi) | 1995-10-23 |
US5646289A (en) | 1997-07-08 |
US5821371A (en) | 1998-10-13 |
CO4480103A1 (es) | 1997-07-09 |
US5929247A (en) | 1999-07-27 |
HU9503045D0 (en) | 1995-12-28 |
NZ280300A (en) | 1997-11-24 |
NO954239D0 (no) | 1995-10-23 |
US5672709A (en) | 1997-09-30 |
US5665745A (en) | 1997-09-09 |
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