YU47369B - Postupak za optičko razdvajanje 3r-(3-karboksibenzil)-6-(5-fluoro-2-benzotiazolil)m etoksi-4r-hromanola - Google Patents

Postupak za optičko razdvajanje 3r-(3-karboksibenzil)-6-(5-fluoro-2-benzotiazolil)m etoksi-4r-hromanola

Info

Publication number
YU47369B
YU47369B YU152290A YU152290A YU47369B YU 47369 B YU47369 B YU 47369B YU 152290 A YU152290 A YU 152290A YU 152290 A YU152290 A YU 152290A YU 47369 B YU47369 B YU 47369B
Authority
YU
Yugoslavia
Prior art keywords
formula
benzothiazolyl
fluoro
compound
chromanola
Prior art date
Application number
YU152290A
Other languages
English (en)
Other versions
YU152290A (sh
Inventor
R.C. Friedman
G.J. Quallich
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU152290A publication Critical patent/YU152290A/sh
Publication of YU47369B publication Critical patent/YU47369B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

POSTUPAK ZA OPTIČKO RAZDVAJANJE 3R-(3-KARBOKSIBENZIL)-6-(5-FLUORO-2-BENZOTIAZOLIL)M ETOKSI-4R-HROMANOLA formule: ili njegove farmaceutski prihvatljive soli, naznačen time, što obuhvata sledeće faze: kombinovanje racemskog cis-3-(3-karbok-sibenzil)-6-(5-fluoro-2-benzotiazolil)metoksi-4-hromanola sa najmanje pola molarne količine kinina u metanolu na temperaturi u opsegu od oko 20 stepeni Celzijusa do oko 65 stepeni Celzijusa, pri takvoj koncentraciji da kininska so jedinjenja formule (I) kristališe suštinski nekontaminirana kininskom soli enatiomera jedinjenja formule (I); konvencionalno regenerisanje navedene kininske soli jedinjenja formule (I) i konvencionalno zakišeljavanje navedene kininske soli sa kiselinom u reakciono-inertnom rastvaraču da bi se dobilo jedinjenje formule (I). Prijava sadrži 1 nezavisni i 3 zavisna zahteva.
YU152290A 1989-08-04 1990-08-06 Postupak za optičko razdvajanje 3r-(3-karboksibenzil)-6-(5-fluoro-2-benzotiazolil)m etoksi-4r-hromanola YU47369B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/389,715 US4987231A (en) 1989-08-04 1989-08-04 Optical resolution method for 3R-(3-carboxybenzyl)-6-(5-fluoro-2-benzothiazolyl)methoxy-4R-chromanol

Publications (2)

Publication Number Publication Date
YU152290A YU152290A (sh) 1992-09-07
YU47369B true YU47369B (sh) 1995-01-31

Family

ID=23539421

Family Applications (1)

Application Number Title Priority Date Filing Date
YU152290A YU47369B (sh) 1989-08-04 1990-08-06 Postupak za optičko razdvajanje 3r-(3-karboksibenzil)-6-(5-fluoro-2-benzotiazolil)m etoksi-4r-hromanola

Country Status (23)

Country Link
US (1) US4987231A (sh)
EP (1) EP0411813A1 (sh)
JP (1) JPH0374384A (sh)
KR (1) KR920011021B1 (sh)
CN (1) CN1024550C (sh)
AU (1) AU613838B2 (sh)
CA (1) CA2022611C (sh)
CZ (1) CZ279737B6 (sh)
DD (1) DD296924A5 (sh)
EG (1) EG19125A (sh)
FI (1) FI92826C (sh)
HU (1) HUT58734A (sh)
IE (1) IE902805A1 (sh)
IL (1) IL95213A (sh)
MY (1) MY105933A (sh)
NO (1) NO903420L (sh)
NZ (1) NZ234761A (sh)
PH (1) PH26568A (sh)
PL (1) PL164164B1 (sh)
PT (1) PT94888A (sh)
RU (1) RU1834889C (sh)
YU (1) YU47369B (sh)
ZA (1) ZA916126B (sh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59198471A (ja) * 1983-04-26 1984-11-10 Canon Inc 複写装置
US5059609A (en) * 1987-10-19 1991-10-22 Pfizer Inc. Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases
US5539128A (en) * 1994-11-30 1996-07-23 Pfizer Inc. Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline
DE102014010979B3 (de) 2014-07-29 2015-11-05 Sew-Eurodrive Gmbh & Co Kg Verwendung eines Anzeigemittels eines Umrichters, Verfahren zum Betreiben eines Umrichters und Umrichter

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA739471B (en) * 1972-12-22 1974-08-28 Hoffmann La Roche Chromane derivatives
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos

Also Published As

Publication number Publication date
PL164164B1 (pl) 1994-06-30
AU6019190A (en) 1991-02-07
DD296924A5 (de) 1991-12-19
CN1024550C (zh) 1994-05-18
CA2022611C (en) 1999-03-23
CA2022611A1 (en) 1991-02-05
MY105933A (en) 1995-02-28
PL286327A1 (en) 1991-03-25
FI92826B (fi) 1994-09-30
AU613838B2 (en) 1991-08-08
US4987231A (en) 1991-01-22
HU904892D0 (en) 1991-01-28
NO903420D0 (no) 1990-08-03
HUT58734A (en) 1992-03-30
YU152290A (sh) 1992-09-07
FI92826C (fi) 1995-01-10
IL95213A0 (en) 1991-06-10
EG19125A (en) 1994-07-30
PH26568A (en) 1992-08-19
IE902805A1 (en) 1991-02-27
KR920011021B1 (ko) 1992-12-26
FI903861A0 (fi) 1990-08-03
IL95213A (en) 1995-01-24
ZA916126B (en) 1992-03-25
NO903420L (no) 1991-02-05
EP0411813A1 (en) 1991-02-06
KR910004610A (ko) 1991-03-29
CN1049160A (zh) 1991-02-13
RU1834889C (ru) 1993-08-15
PT94888A (pt) 1991-04-18
JPH0374384A (ja) 1991-03-28
NZ234761A (en) 1991-09-25
CZ279737B6 (cs) 1995-06-14

Similar Documents

Publication Publication Date Title
PT97562A (pt) Processo para a preparacao de uma composicao farmaceutica contendo um nucleo de diclofenac ou de piroxicamo e um revestimento de cobertura de uma prostaglandina
PT89769A (pt) Processo para a preparacao de derivados do acido 3-alcenil-1-azabiciclo-{3,2,0}hept-2-eno-2-carboxilico
FI906438A0 (fi) Menetelmä uusien, terapeuttisesti käyttökelpoisten A-nor-steroidi-3-karboksyylihappojohdannaisten valmistamiseksi
PT82824B (pt) Processo para a preparacao de (4-piperidinilmetil e-hetero)purinas
EA199800477A1 (ru) Производные хинолина
MA21722A1 (fr) Derives de 2 - aminopyrimidinones utiles notamment comme antagonistes des neurotransmetteurs et procede pour leur preparation .
DK162992C (da) Analogifremgangsmaade til fremstilling af 1-piperazinyl-3-phenyl-indanderivater eller syreadditionssalte deraf
BG92179A (bg) Метод за получаване на 7-заместена-хепт-6-еноена и -хептаноена киселина и техни производни и междинни съединения
DK0422485T3 (da) Quinoloncarboxylsyrederivater, fremgangsmåder til deres fremstilling samt deres anvendelse som antivirale midler
IT1158025B (it) Derivati di 3-ammino pregn-5-ene e loro sali, procedimento per la loro preparazione, per l'applicazione come medicamenti e composizioni che li contengono
YU47369B (sh) Postupak za optičko razdvajanje 3r-(3-karboksibenzil)-6-(5-fluoro-2-benzotiazolil)m etoksi-4r-hromanola
ES8306137A1 (es) "procedimiento para la preparacion de nuevas amidas de acidos carboxilicos".
IT8019992A0 (it) Derivati dell'acido 3-fosfonocefalosporanico, procedimenti per la loro preparazione e composizione farmaceutica che li comprende.
NO960268L (no) Nye dialkoksypyridinylbenzimidazolderivater
PT93450A (pt) Processo para a preparacao de novos derivados azetidinicos de acidos piridinocarboxilicos e de composicoes farmaceuticas que os contem
DK119188D0 (da) Substituerede pyridin-2,4-dicarboxylsyrederivater, fremgangsmaader til deres fremstilling samt laegemiddel indeholdende forbindelserne
PT84819B (pt) Processo para a preparacao de compostos 2-piridil-penem
PT88088A (pt) Processo para a preparacao de derivados de piperidina e de composicoes farmaceuticas que os contem
ATE3769T1 (de) 1-imidazol-2-yliden-3-thienyl-harnstoffderivate verfahren zu deren herstellung und pharmazeutische zusammensetzungen.
PT80791A (fr) Procede de preparation de nouvelles phenyl-naphtiridines utiles notamment comme medicaments anti-ulceres
ES515895A0 (es) "un procedimiento para la preparacion de un compuesto de imidazol".
PT97541A (pt) Processo para a preparacao de indoles substituidos
PT82175B (pt) Processo para preparacao de novos derivados de 3-piridilmetilnaftalina e de composicoes farmceuticas que os contem
DK0424504T3 (da) Nye 9alfa-hydroxy-3-oxo-4,24(25)-stigmastadien-26-syrederivater, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater med indhold deraf
DE3275645D1 (de) N1-acyl-3-amino-1,2,3,4-tetrahydroquinoline compounds