YU47119B - Nov postupak za pripremanje alfa-(1-metiletil)-3,4-dimetoksibenzen-acetonitrila - Google Patents
Nov postupak za pripremanje alfa-(1-metiletil)-3,4-dimetoksibenzen-acetonitrilaInfo
- Publication number
- YU47119B YU47119B YU69688A YU69688A YU47119B YU 47119 B YU47119 B YU 47119B YU 69688 A YU69688 A YU 69688A YU 69688 A YU69688 A YU 69688A YU 47119 B YU47119 B YU 47119B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- formula
- alpha
- methylethyl
- hours
- boiling point
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/37—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by etherified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
NOV POSTUPAK ZA PRIPREMANJE ALFA-(1-METILETIL)-3,4-DIMETOKSIBENZEN-ACETONITRILA, formule: naznacen time, sto reaguje izobutiril-3,4-dimetoksibenzen, formule: sa alfa-halogenestrom, formule X-CH2-COOR VII u kojoj X predstavlja atom halogena, a R predstavlja alkil radikal koji je nerazgranat ili je razgranat, a sadrzi od 1 do 6 atoma ugljenika, u prisustvu alkalnog sredstva, izabranog izmedju alkoksida alkalnog metala, formule R1O-Me+ VIII u kojoj Me+ predstavlja katjon alkalnog metala, a R1 je alkil radikal, koji je nerazgranat ili razgranat, a sadrzi od 1 do 6 atoma ugljenika, natrijum-amida ili natrijum-hidrida, a u datom slucaju u prisustvu rastvaraca, izabranog izmedju aromatskog ugljovodonika i alkohola, koji je nerazgranat ili razgranat, a sadrzi od 1 do 6 atoma ugljenika, ili njihovih smesa, u trajanju od oko 1 do oko 24 sata, na temperaturi izmedju -25°C i temperature kljucanja reakcione smese, sto se nastali estar glicidne kiseline, formule u kojoj R ima gore navedeno znacenje, alkalno hidrolizuje, na temperaturi izmedju oko 0°C i temperature kljucanja reakcione smese, u trajanju izmedju oko 1 do oko 12 sati, da bi se dobila alkalna so epoksi kiseline, formule u kojoj Me+ ima gore navedeno znacenje, sto se jedinjenje formule IV dekarboksiluje, pri temperaturi izmedju oko 20°C i temperature kljucanja smese, u trajanju oko 1 do oko 16 sati, da bi se dobio alfa-(1-metiletil)-3,4-dimetoksibenzenacetaldehid, formule sto se pomenuti aldehid, formule V, tretira sa hidroksilamin hidrohloridom, na temperaturi izmedju oko 0°C i temperature kljucanja reakcione smese, u trajanju od oko 0,5 do oko 16 sati, kako bi se dobio alfa-(1-metiletil)-3,4-dimetoksibenzenacetaldoksim, formule i sto se pomenuti oksim formule VI, dehidratise kako bi se dobio zeljeni nitril, formule I. Prijava sadrzi jos 7 zavisnih zahteva.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI8810696A SI8810696A (sl) | 1987-04-08 | 1988-04-07 | Nov postopek za pripravo alfa-(1-metiletil)-3,4-dimetoksibenzenacetonitrila |
| HRP-696/88A HRP940590B1 (en) | 1987-04-08 | 1994-09-26 | New process for the synthesis of the alpha-(1-methylethyl)-3,4-dimethoxybenzene-acetonitrile |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8720019A IT1215409B (it) | 1987-04-08 | 1987-04-08 | Processo per la sintesi dell'alfa-(1-metiletil)-3,4-dimetossibenzeneacetonitrile. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU69688A YU69688A (en) | 1989-10-31 |
| YU47119B true YU47119B (sh) | 1994-12-28 |
Family
ID=11163169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU69688A YU47119B (sh) | 1987-04-08 | 1988-04-07 | Nov postupak za pripremanje alfa-(1-metiletil)-3,4-dimetoksibenzen-acetonitrila |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5097058A (sh) |
| EP (1) | EP0285890B1 (sh) |
| JP (1) | JPH0717592B2 (sh) |
| KR (1) | KR940011907B1 (sh) |
| AR (1) | AR243158A1 (sh) |
| AT (1) | ATE82566T1 (sh) |
| AU (1) | AU605571B2 (sh) |
| CA (1) | CA1327048C (sh) |
| DD (1) | DD273250A5 (sh) |
| DE (2) | DE3875996T2 (sh) |
| DK (1) | DK189088A (sh) |
| ES (1) | ES2006418T3 (sh) |
| FI (1) | FI93950C (sh) |
| GR (2) | GR880300180T1 (sh) |
| IE (1) | IE62321B1 (sh) |
| IL (1) | IL85836A (sh) |
| IT (1) | IT1215409B (sh) |
| NO (1) | NO168032C (sh) |
| NZ (1) | NZ223966A (sh) |
| PL (1) | PL152661B1 (sh) |
| PT (1) | PT87187B (sh) |
| YU (1) | YU47119B (sh) |
| ZA (1) | ZA881961B (sh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1229214B (it) * | 1989-03-31 | 1991-07-25 | Alfa Wassermann S P A Contrada | Processo per la sintesi della n metil 3,4 dimetossifeniletilamina |
| ES2054436T3 (es) * | 1990-12-28 | 1994-08-01 | Unilever Nv | Pastas mejoradas, pre-fermentadas, ultracongeladas. |
| US5457222A (en) * | 1991-07-25 | 1995-10-10 | Kao Corporation | Process for producing nitrile |
| EP1445248A4 (en) | 2001-11-12 | 2006-03-22 | Kuraray Co | PROCESSES FOR PREPARING CYCLOPROPYLETHANOL, CYCLOPROPYLACETONITRILE, AND INTERMEDIATES THEREOF |
| JP2010180142A (ja) * | 2009-02-03 | 2010-08-19 | Kuraray Co Ltd | シクロヘキサンカルボニトリルの製造方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1154810B (de) * | 1961-04-01 | 1963-09-26 | Knoll Ag | Verfahren zur Herstellung basisch substituierter Phenylacetonitrile |
| US3435075A (en) * | 1965-06-15 | 1969-03-25 | Merck & Co Inc | Process for preparing (halophenyl) alkyl ketone compounds |
| US3415866A (en) * | 1966-03-14 | 1968-12-10 | Colgate Palmolive Co | alpha-alkylidene-3,4-disubstituted-phenylacetonitriles |
| JPS5118940B2 (sh) * | 1971-12-25 | 1976-06-14 | ||
| US3997608A (en) * | 1973-07-05 | 1976-12-14 | Richardson-Merrell Inc. | N-substituted-dihydroxyphenethylamines |
| US4235807A (en) * | 1979-07-02 | 1980-11-25 | Thompson-Hayward Chemical Company | Synthesis of 2,6-disubstituted benzonitriles |
| US4456562A (en) * | 1981-12-02 | 1984-06-26 | Sumitomo Chemical Company, Limited | Process for producing nitriles |
| DE3468863D1 (en) * | 1984-06-15 | 1988-02-25 | Heumann Ludwig & Co Gmbh | Method for the preparation of phenylacetonitrile substituted by a basic radical |
| US4593042A (en) * | 1985-10-18 | 1986-06-03 | G. D. Searle & Co. | Bicyclo-substituted phenylacetonitrile derivatives |
-
1987
- 1987-04-08 IT IT8720019A patent/IT1215409B/it active
-
1988
- 1988-03-18 ZA ZA881961A patent/ZA881961B/xx unknown
- 1988-03-21 ES ES88104469T patent/ES2006418T3/es not_active Expired - Lifetime
- 1988-03-21 DE DE8888104469T patent/DE3875996T2/de not_active Expired - Fee Related
- 1988-03-21 EP EP88104469A patent/EP0285890B1/en not_active Expired - Lifetime
- 1988-03-21 NZ NZ223966A patent/NZ223966A/xx unknown
- 1988-03-21 DE DE198888104469T patent/DE285890T1/de active Pending
- 1988-03-21 AT AT88104469T patent/ATE82566T1/de not_active IP Right Cessation
- 1988-03-23 IL IL85836A patent/IL85836A/xx not_active IP Right Cessation
- 1988-04-06 PL PL1988271678A patent/PL152661B1/pl unknown
- 1988-04-06 KR KR1019880003818A patent/KR940011907B1/ko not_active IP Right Cessation
- 1988-04-06 CA CA000563389A patent/CA1327048C/en not_active Expired - Fee Related
- 1988-04-06 DD DD88314466A patent/DD273250A5/de not_active IP Right Cessation
- 1988-04-07 DK DK189088A patent/DK189088A/da not_active Application Discontinuation
- 1988-04-07 PT PT87187A patent/PT87187B/pt not_active IP Right Cessation
- 1988-04-07 YU YU69688A patent/YU47119B/sh unknown
- 1988-04-07 FI FI881611A patent/FI93950C/fi not_active IP Right Cessation
- 1988-04-07 AU AU14375/88A patent/AU605571B2/en not_active Ceased
- 1988-04-07 AR AR88310506A patent/AR243158A1/es active
- 1988-04-07 IE IE103388A patent/IE62321B1/en not_active IP Right Cessation
- 1988-04-07 NO NO881487A patent/NO168032C/no not_active IP Right Cessation
- 1988-04-08 JP JP63087039A patent/JPH0717592B2/ja not_active Expired - Fee Related
-
1989
- 1989-06-22 GR GR88300180T patent/GR880300180T1/el unknown
-
1990
- 1990-04-25 US US07/512,909 patent/US5097058A/en not_active Expired - Lifetime
-
1992
- 1992-11-30 GR GR920402453T patent/GR3006382T3/el unknown
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