YU47116B - Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata - Google Patents

Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata

Info

Publication number
YU47116B
YU47116B YU211087A YU211087A YU47116B YU 47116 B YU47116 B YU 47116B YU 211087 A YU211087 A YU 211087A YU 211087 A YU211087 A YU 211087A YU 47116 B YU47116 B YU 47116B
Authority
YU
Yugoslavia
Prior art keywords
carbon atoms
alkyl
halogen
alkoxy
substituted
Prior art date
Application number
YU211087A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU211087A (en
Inventor
R.A. Bergman
H. Bundgaard
P.L. Lindberg
G.E. Sunden
Original Assignee
Aktiebolaget Hassle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8604998A external-priority patent/SE8604998D0/xx
Priority claimed from SE8605551A external-priority patent/SE8605551D0/xx
Priority claimed from SE8704049A external-priority patent/SE8704049D0/xx
Application filed by Aktiebolaget Hassle filed Critical Aktiebolaget Hassle
Publication of YU211087A publication Critical patent/YU211087A/xx
Publication of YU47116B publication Critical patent/YU47116B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU211087A 1986-11-21 1987-11-20 Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata YU47116B (sh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8604998A SE8604998D0 (sv) 1986-11-21 1986-11-21 Novel pharmacological compounds
SE8605551A SE8605551D0 (sv) 1986-12-23 1986-12-23 Novel pharmacological compounds
SE8704049A SE8704049D0 (sv) 1987-10-16 1987-10-16 Novel pharmacological compounds

Publications (2)

Publication Number Publication Date
YU211087A YU211087A (en) 1988-12-31
YU47116B true YU47116B (sh) 1994-12-28

Family

ID=27355365

Family Applications (1)

Application Number Title Priority Date Filing Date
YU211087A YU47116B (sh) 1986-11-21 1987-11-20 Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata

Country Status (24)

Country Link
EP (3) EP0279149B1 (en:Method)
JP (1) JPH02500744A (en:Method)
KR (1) KR890700125A (en:Method)
AT (1) ATE84032T1 (en:Method)
AU (1) AU612129B2 (en:Method)
DE (1) DE3783356T2 (en:Method)
DK (1) DK365488D0 (en:Method)
EG (1) EG18379A (en:Method)
ES (1) ES2052603T3 (en:Method)
FI (1) FI892454L (en:Method)
GR (1) GR3007385T3 (en:Method)
HU (1) HU204814B (en:Method)
IE (2) IE940326L (en:Method)
IL (1) IL84504A (en:Method)
IS (1) IS1565B (en:Method)
LV (1) LV10954B (en:Method)
MY (1) MY101784A (en:Method)
NO (1) NO173998C (en:Method)
NZ (2) NZ234564A (en:Method)
PL (1) PL157655B1 (en:Method)
PT (1) PT86186B (en:Method)
RU (1) RU2062778C1 (en:Method)
WO (1) WO1988003921A1 (en:Method)
YU (1) YU47116B (en:Method)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8801907D0 (sv) * 1988-05-20 1988-05-20 Haessle Ab Novel pharmacological compounds
EP0436025A4 (en) * 1988-09-20 1991-09-11 Hisamitsu Pharmaceutical Co. Inc. Novel dibenz b,e)oxepin derivatives
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
WO1991019712A1 (en) * 1990-06-20 1991-12-26 Aktiebolaget Astra Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
CA2053527C (en) * 1990-10-17 2002-03-12 Takashi Sohda Pyridine derivatives, their production and use
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
JP2759228B2 (ja) * 1992-05-21 1998-05-28 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
WO1994026279A1 (en) * 1993-05-18 1994-11-24 The Upjohn Company Bisphosphonate esters for treating gastric disorders
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
EP0983263A1 (en) * 1997-05-30 2000-03-08 Dr. Reddy's Research Foundation Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
CA2317008C (en) * 1997-12-31 2009-01-20 The University Of Kansas Water soluble prodrugs of tertiary amine containing drugs and methods of making thereof
ZA9810765B (en) * 1998-05-28 1999-08-06 Ranbaxy Lab Ltd Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.
US6420384B2 (en) 1999-12-17 2002-07-16 Ariad Pharmaceuticals, Inc. Proton pump inhibitors
US20040039027A1 (en) * 2000-10-12 2004-02-26 Keiji Kamiyama Benzimidazole compounds, process for producing the same and use thereof
WO2003027098A1 (en) * 2001-09-25 2003-04-03 Takeda Chemical Industries, Ltd. Benzimidazole compound, process for producing the same, and use thereof
KR100788778B1 (ko) * 2002-07-19 2007-12-27 윈스턴 파마슈티컬즈, 엘엘씨 벤즈이미다졸 유도체 및 이들의 프로톤 펌프 억제제의프로드럭으로서의 이용
GB0400781D0 (en) * 2004-01-14 2004-02-18 Novartis Ag Organic compounds
CA2577089A1 (en) * 2004-08-27 2006-03-02 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
ATE467637T1 (de) * 2005-07-28 2010-05-15 Intervet Int Bv Neue benzimidazol(thio)carbamate mit antiparasitischer wirkung und ihre synthese
WO2016061190A1 (en) 2014-10-14 2016-04-21 The Board Of Trustees Of The Leland Stanford Junior University Method for treating neurodegenerative diseases
IL285248B2 (en) 2015-12-15 2025-10-01 Univ Leland Stanford Junior It is recommended for use as a drug for the prevention and/or treatment of cognitive impairment associated with aging.
US12195432B2 (en) * 2018-08-06 2025-01-14 The Board Of Trustees Of The Leland Stanford Junior University 2-arylbenzimidazoles as Ppargc1a activators for treating neurodegenerative diseases
US12459890B2 (en) * 2019-08-20 2025-11-04 Ono Pharmaceutical Co., Ltd. Salt and crystal form of compound having agonistic activity to S1P5 receptor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (en:Method) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS5836312B2 (ja) * 1978-08-21 1983-08-08 日本電信電話株式会社 通信用平衡ケ−ブル線路の障害位置測定方式
JPS5687818A (en) * 1979-12-19 1981-07-16 Ishikawajima Harima Heavy Ind Co Ltd Reflex type position detector
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
JPS57137860A (en) * 1981-02-20 1982-08-25 Sumitomo Electric Ind Ltd Optical tachometer
JPS5999597A (ja) * 1982-11-30 1984-06-08 株式会社東芝 光学測定装置
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
JPS6020051U (ja) * 1983-07-19 1985-02-12 三洋電機株式会社 カセツト収納装置
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds

Also Published As

Publication number Publication date
LV10954A (lv) 1995-12-20
ATE84032T1 (de) 1993-01-15
JPH02500744A (ja) 1990-03-15
EP0279149A2 (en) 1988-08-24
PT86186B (pt) 1990-08-31
GR3007385T3 (en:Method) 1993-07-30
WO1988003921A1 (en) 1988-06-02
MY101784A (en) 1992-01-17
DE3783356D1 (de) 1993-02-11
EP0279149A3 (en) 1988-08-31
HUT51269A (en) 1990-04-28
RU2062778C1 (ru) 1996-06-27
YU211087A (en) 1988-12-31
NO883229L (no) 1988-09-16
FI892454A7 (fi) 1989-05-19
IE61178B1 (en) 1994-10-05
HU204814B (en) 1992-02-28
FI892454A0 (fi) 1989-05-19
ES2052603T3 (es) 1994-07-16
DK365488A (da) 1988-07-01
NZ222495A (en) 1991-04-26
AU612129B2 (en) 1991-07-04
AU8330287A (en) 1988-06-16
NO883229D0 (no) 1988-07-20
NO173998C (no) 1994-03-02
KR890700125A (ko) 1989-03-02
EP0279149B1 (en) 1992-12-30
IS3284A7 (is) 1988-05-22
FI892454L (fi) 1989-05-19
IL84504A (en) 1994-10-07
EG18379A (en) 1992-11-30
DE3783356T2 (de) 1993-04-15
PL157655B1 (pl) 1992-06-30
IS1565B (is) 1994-12-13
EP0332647A1 (en) 1989-09-20
LV10954B (en) 1996-08-20
IE940326L (en) 1988-05-21
NZ234564A (en) 1991-04-26
EP0510719A1 (en) 1992-10-28
PT86186A (en) 1987-12-01
PL268927A1 (en) 1989-01-23
IE873125L (en) 1988-05-21
NO173998B (no) 1993-11-22
DK365488D0 (da) 1988-07-01

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