YU42550B - Process for preparing new octapeptide analogs of an angiotensin-ii, containing remaining part of alpha-hydroxi-carboxylic acid in position 8 - Google Patents

Process for preparing new octapeptide analogs of an angiotensin-ii, containing remaining part of alpha-hydroxi-carboxylic acid in position 8

Info

Publication number
YU42550B
YU42550B YU93/81A YU9381A YU42550B YU 42550 B YU42550 B YU 42550B YU 93/81 A YU93/81 A YU 93/81A YU 9381 A YU9381 A YU 9381A YU 42550 B YU42550 B YU 42550B
Authority
YU
Yugoslavia
Prior art keywords
radical
group
nitrogen atom
protective group
atom
Prior art date
Application number
YU93/81A
Other languages
English (en)
Other versions
YU9381A (en
Inventor
O Nyeki
L Kisfaludy
E Karpati
L Szpornyl
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of YU9381A publication Critical patent/YU9381A/xx
Publication of YU42550B publication Critical patent/YU42550B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/14Angiotensins: Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
YU93/81A 1980-01-18 1981-01-16 Process for preparing new octapeptide analogs of an angiotensin-ii, containing remaining part of alpha-hydroxi-carboxylic acid in position 8 YU42550B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU8080100A HU181008B (en) 1980-01-18 1980-01-18 Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position

Publications (2)

Publication Number Publication Date
YU9381A YU9381A (en) 1983-09-30
YU42550B true YU42550B (en) 1988-10-31

Family

ID=10947908

Family Applications (1)

Application Number Title Priority Date Filing Date
YU93/81A YU42550B (en) 1980-01-18 1981-01-16 Process for preparing new octapeptide analogs of an angiotensin-ii, containing remaining part of alpha-hydroxi-carboxylic acid in position 8

Country Status (19)

Country Link
US (1) US4330532A (sv)
EP (1) EP0034260B1 (sv)
JP (1) JPS56142251A (sv)
AT (1) ATE4197T1 (sv)
AU (1) AU541000B2 (sv)
CA (1) CA1149377A (sv)
CS (1) CS219939B2 (sv)
DE (1) DE3160608D1 (sv)
DK (1) DK149777C (sv)
ES (1) ES8201129A1 (sv)
FI (1) FI73225C (sv)
HU (1) HU181008B (sv)
IL (1) IL61922A (sv)
IN (1) IN153279B (sv)
NO (1) NO151409C (sv)
PH (1) PH17196A (sv)
PL (1) PL130448B1 (sv)
SU (1) SU993816A3 (sv)
YU (1) YU42550B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182264A (en) * 1986-03-07 1993-01-26 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
DE19529604A1 (de) * 1995-08-11 1997-02-13 Bayer Ag Endoparasitizide Mittel auf Basis von Didepsipeptiden, neue Didepsipeptide und ein Verfahren zu ihrer Herstellung
US9572856B2 (en) * 2009-12-16 2017-02-21 The George Washington University a Congressionally Chartered Not-for-Profit Corporation Method of treating low blood pressure
EP3858437A1 (en) 2013-04-26 2021-08-04 La Jolla Pharma, LLC Compositions and methods for treating renal failure
WO2015095535A1 (en) 2013-12-18 2015-06-25 The George Washington University, A Congressional Chartered Not-For-Profit Corporation Angiotensin ii alone or in combination for the treatment of hypotension
US10406201B2 (en) 2016-01-07 2019-09-10 La Jolla Pharma, Llc Methods for administering angiotensin II
WO2018191678A1 (en) 2017-04-14 2018-10-18 La Jolla Pharmaceutical Company Methods for administering angiotensin ii

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947575A (en) * 1969-06-30 1976-03-30 E. R. Squibb & Sons, Inc. Peptides as argiotensin converting enzyme inhibitors
DE2323322A1 (de) * 1973-05-09 1974-11-28 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3923770A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus {8 Me{hd 2{b Gly{hu 1{b , Ile{hu 8{b {9 -Anziotensin II as an angiotensin antagonist
US3923769A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus {8 N-Me-Ile{40 ,Ile{hu 8{b {9 -Angiotensin II as an angiotensin antagonist
US3915948A (en) * 1974-08-05 1975-10-28 Morton Norwich Products Inc Sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-proline
DE2457463A1 (de) * 1974-12-05 1976-06-10 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3975365A (en) * 1975-01-27 1976-08-17 G. D. Searle & Co. Inhibitory octapeptides angiotensin II
US3976770A (en) * 1975-02-10 1976-08-24 Francis Merlin Bumpus Sar'-(OMe)Thr8 Angiotensin II as an angiotensin II antagonist
HU177134B (en) * 1977-07-18 1981-07-28 Richter Gedeon Vegyeszet Process for preparing angiotensin ii analogues containing alpha-hydroxy-acid in position 1 with angiotensin ii antagonist activity
HU177133B (en) * 1977-07-18 1981-07-28 Richter Gedeon Vegyeszet Process for preparing angiotensin ii analogues containing alpha- amino-oxy-acid in position 1 with angiotensin ii antagonist activity

Also Published As

Publication number Publication date
JPS56142251A (en) 1981-11-06
AU541000B2 (en) 1984-12-13
CS219939B2 (en) 1983-03-25
PH17196A (en) 1984-06-19
PL229223A1 (sv) 1982-03-01
SU993816A3 (ru) 1983-01-30
AU6627681A (en) 1981-07-23
NO151409B (no) 1984-12-27
ES498583A0 (es) 1981-12-01
DK149777C (da) 1987-04-21
US4330532A (en) 1982-05-18
FI73225C (sv) 1987-09-10
DE3160608D1 (en) 1983-08-25
EP0034260B1 (de) 1983-07-20
NO810149L (no) 1981-07-20
FI73225B (fi) 1987-05-29
IL61922A (en) 1984-01-31
IL61922A0 (en) 1981-02-27
EP0034260A1 (de) 1981-08-26
ATE4197T1 (de) 1983-08-15
NO151409C (no) 1985-04-10
CA1149377A (en) 1983-07-05
DK20481A (da) 1981-07-19
IN153279B (sv) 1984-06-23
FI810123L (fi) 1981-07-19
PL130448B1 (en) 1984-08-31
HU181008B (en) 1983-05-30
ES8201129A1 (es) 1981-12-01
YU9381A (en) 1983-09-30
DK149777B (da) 1986-09-29

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