YU215580A - Process for obtaining beta-carboline-3-carboxylic acid derivatives - Google Patents

Process for obtaining beta-carboline-3-carboxylic acid derivatives

Info

Publication number
YU215580A
YU215580A YU02155/80A YU215580A YU215580A YU 215580 A YU215580 A YU 215580A YU 02155/80 A YU02155/80 A YU 02155/80A YU 215580 A YU215580 A YU 215580A YU 215580 A YU215580 A YU 215580A
Authority
YU
Yugoslavia
Prior art keywords
carboline
carboxylic acid
acid derivatives
obtaining beta
beta
Prior art date
Application number
YU02155/80A
Other languages
English (en)
Inventor
U Eder
G Neef
D Rahtz
A Huth
R Schmiechner
C T Braestrup
M C Nielsen
J A Cristensen
M Engelstoft
H Schou
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK88980A external-priority patent/DK88980A/da
Priority claimed from DE19803015816 external-priority patent/DE3015816A1/de
Priority claimed from DE19803023567 external-priority patent/DE3023567A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of YU215580A publication Critical patent/YU215580A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
YU02155/80A 1979-08-29 1980-08-28 Process for obtaining beta-carboline-3-carboxylic acid derivatives YU215580A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK362279 1979-08-29
DK88980A DK88980A (da) 1980-02-29 1980-02-29 Beta-carbonline-3-carboxylsyrederivater og fremgangsmaader til fremstilling af samme
DE19803015816 DE3015816A1 (de) 1980-04-22 1980-04-22 4-substituierte- (beta) -carbolin-3-carbonsaeurederivate, ihre herstellung und verwendung
DE19803023567 DE3023567A1 (de) 1980-06-20 1980-06-20 Substituierte (beta) -carbolin-3-carbonsaeurederivate

Publications (1)

Publication Number Publication Date
YU215580A true YU215580A (en) 1984-02-29

Family

ID=27432526

Family Applications (1)

Application Number Title Priority Date Filing Date
YU02155/80A YU215580A (en) 1979-08-29 1980-08-28 Process for obtaining beta-carboline-3-carboxylic acid derivatives

Country Status (16)

Country Link
US (2) US4371536A (fr)
EP (1) EP0030254B1 (fr)
CA (1) CA1150246A (fr)
DD (1) DD152935A5 (fr)
DE (1) DE3069559D1 (fr)
ES (1) ES8106305A1 (fr)
FI (1) FI68829C (fr)
HU (1) HU186744B (fr)
IE (1) IE50229B1 (fr)
IL (1) IL60906A (fr)
NO (1) NO155055C (fr)
NZ (1) NZ194747A (fr)
PL (1) PL226479A1 (fr)
PT (1) PT71744B (fr)
RO (1) RO80265B (fr)
YU (1) YU215580A (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3240514A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Ss-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3240513A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung
DK149270C (da) * 1983-05-27 1986-08-25 Schering Ag Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater
DE3322895A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)
DE3322894A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h)
DE3335323A1 (de) 1983-09-27 1985-04-04 Schering AG, 1000 Berlin und 4709 Bergkamen Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
FR2555988A1 (fr) * 1983-12-06 1985-06-07 Centre Nat Rech Scient Derive de b-carbolines, procede pour leurs preparations et medicament les contenant
DK240184D0 (da) * 1984-05-15 1984-05-15 Ferrosan As Beta-carboline-3-carboxylic acid derivatives and method of preparing the same
DE3535928A1 (de) * 1985-10-04 1987-04-09 Schering Ag Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3609699A1 (de) * 1986-03-20 1987-09-24 Schering Ag 5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
WO1988002751A1 (fr) * 1986-10-13 1988-04-21 Asahi Kasei Kogyo Kabushiki Kaisha Derives de pyridine
DE4029389A1 (de) * 1990-09-13 1992-03-26 Schering Ag Verfahren zur herstellung von (beta)-carbolin-derivaten
US5350750A (en) * 1991-04-27 1994-09-27 Schering Aktiengesellschaft β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents
GB9508195D0 (en) * 1995-04-20 1995-06-07 Univ British Columbia Novel biologically active compounds and compositions,their use and derivation
DK0891187T3 (da) * 1996-04-04 2002-04-29 Hoffmann La Roche Anvendelse af tetrahydro-beta-carbolin-derivater som antimetastatiske midler
DE69722220T2 (de) * 1996-08-09 2004-02-19 Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield 4-substituierte beta-carboline als immunomodulatoren
UA74826C2 (en) 2000-05-17 2006-02-15 Ortho Mcneil Pharm Inc ?-carboline derivatives as phosphodiesterase inhibitors
AR036040A1 (es) * 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
BR0213612A (pt) 2001-10-02 2004-08-24 Upjohn Co Composto, composição farmacêutica, uso do composto e método para tratamento de doença ou condição
EP1442037A1 (fr) 2001-11-09 2004-08-04 PHARMACIA & UPJOHN COMPANY Composes heterocycliques fusionnes avec un groupe phenyl-azabicyclique et leur utilisation en tant que ligands de recepteur nachr alpha 7
US20030176456A1 (en) * 2001-12-21 2003-09-18 June Harry L. Methods for reducing alcohol cravings in chronic alcoholics
BR0307735A (pt) 2002-02-19 2005-01-25 Upjohn Co Carboxamidas heteroaromáticas com ligação-n em ponte biciclìcas fundidas para o tratamento de doença
PA8586801A1 (es) * 2002-10-31 2005-02-04 Pfizer Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso
EP1590349A1 (fr) 2003-01-27 2005-11-02 Pfizer Inc. Inhibiteurs de vih-integrase, compositions pharmaceutiques et methodes d'utilisation desdits inhibiteurs
CN100503607C (zh) 2003-06-02 2009-06-24 新疆华世丹药物研究有限责任公司 去氢骆驼蓬碱衍生物类化合物及其应用
EP1751157B1 (fr) 2004-04-26 2007-10-03 Pfizer Inc. Inhibiteurs de l'enzyme integrase du vih
BRPI0510319A (pt) 2004-04-26 2007-10-16 Pfizer inibidores da enzima integrase de hiv
CA2623506A1 (fr) * 2005-10-07 2007-04-19 Pfizer Products Inc. Inhibiteurs de l'enzyme integrase du vih
AU2013205135B2 (en) * 2006-10-28 2015-11-05 Forum Pharmaceuticals Inc. Inhibitors of histone deacetylase
CN103275067B (zh) 2006-10-28 2015-09-02 梅特希尔基因公司 组蛋白脱乙酰酶抑制剂
WO2009143445A1 (fr) * 2008-05-22 2009-11-26 The Uwm Research Foundation, Inc Aza-bêta-carbolines et leurs procédés d’utilisation
CN104211699A (zh) * 2013-06-05 2014-12-17 首都医科大学 β-咔啉衍生物,其制备,纳米结构,抗肿瘤活性和应用
CN104628722B (zh) * 2015-01-30 2016-06-22 华南农业大学 一种骆驼蓬碱酰胺类化合物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA786351A (en) * 1968-05-28 Leonard Frederick PROCESS FOR THE PREPARATION OF NEW .beta.-CARBOLIN-CARBOXYLIC ACID AMIDE DERIVATIVES
ES273769A1 (es) * 1961-01-18 1962-06-01 Geigy Ag J R Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico
GB1084256A (fr) * 1963-11-06
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3322894A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h)
DK240184D0 (da) * 1984-05-15 1984-05-15 Ferrosan As Beta-carboline-3-carboxylic acid derivatives and method of preparing the same
DK240084D0 (da) * 1984-05-15 1984-05-15 Ferrosan As New beta-carboline-3-oxadiazolyl derivatives
DE3504045A1 (de) * 1985-02-04 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinen durch dehydrierung

Also Published As

Publication number Publication date
FI802720A (fi) 1981-03-01
DE3069559D1 (en) 1984-12-06
EP0030254A1 (fr) 1981-06-17
PL226479A1 (fr) 1981-10-30
NZ194747A (en) 1988-11-29
DD152935A5 (de) 1981-12-16
CA1150246A (fr) 1983-07-19
ES494590A0 (es) 1981-08-16
IE801806L (en) 1981-02-28
NO155055B (no) 1986-10-27
ES8106305A1 (es) 1981-08-16
IL60906A (en) 1985-11-29
NO155055C (no) 1987-02-04
FI68829C (fi) 1985-11-11
PT71744B (en) 1981-06-08
US5010077A (en) 1991-04-23
US4371536A (en) 1983-02-01
PT71744A (en) 1980-09-01
RO80265A (fr) 1983-04-29
HU186744B (en) 1985-09-30
FI68829B (fi) 1985-07-31
IL60906A0 (en) 1980-10-26
RO80265B (ro) 1983-04-30
EP0030254B1 (fr) 1984-10-31
IE50229B1 (en) 1986-03-05
NO802546L (no) 1981-03-02

Similar Documents

Publication Publication Date Title
YU215580A (en) Process for obtaining beta-carboline-3-carboxylic acid derivatives
YU41743B (en) Process for obtaining 6-beta-hydroxy-alkyl-penicillanic acid derivatives
YU80379A (en) Process for obtaining thioethianic acid derivatives
YU42807B (en) Process for preparing phthalazine-4-yl-acetic acid derivatives
YU42064B (en) Process for obtaining new glycevol derivatives
PT72079A (en) Process for the preparation of 7-acylamino-3-vinylcephalosporanic acid derivatives
YU167680A (en) Process for obtaining triiodated 5-amino-isophthalic acid derivatives
PT69093A (en) Process for preparing 4-pyridone-3-carboxylic acid derivatives
YU145480A (en) Process for obtaining new hydroxyamino-eburnane derivatives
YU125780A (en) Process for obtaining 7-aminodeacetoxy cephalosporanic acid derivatives
PT71405A (en) Process for preparing alkanoic acid derivatives
YU236180A (en) Process for obtaining 15-sulfonamido-prostaglandin derivatives
PT67783A (en) Process for preparing oleanoic acid derivatives
HU178840B (en) Process for preparing 6-chloro-alpha-methyl-carbazol-2-acetic acid
YU42675B (en) Process for obtaining new nitroalkanol derivatives
YU123177A (en) Process for obtaining indolyl-acetic acid derivatives
YU41918B (en) Process for obtaining 5-(2-hydroxy-3-thiopropoxy)-chromone-2-carboxylic acid
PT71542B (en) Process for preparing dihydronicotinic acid derivatives
HU174071B (hu) Sposob poluchenija proizvodnykh oksazolino-azetidinil-pentenovoj kisloty
YU42517B (en) Process for obtaining new carbonic acid derivatives
YU100280A (en) Process for obtaining new aminoisoquinazoline derivatives
YU40848B (en) Process for obtaining benzoxazolyl - propionic acid derivatives
YU32578A (en) Process for preparing 3-carboyphenyl-acetic acid derivatives
PT71253A (en) Process for preparing 6-alpha e 6-beta-substituted penicilanic acid derivatives
YU151380A (en) Process for obtaining 5-mercaptotetrazolyl-1-acetic acid