YU128883A - Process for preparing 4-(2-hydroxy-3-(4-phenoxy-methyl-pyperidino)-propoxy)indol and salts and esters thereof - Google Patents

Process for preparing 4-(2-hydroxy-3-(4-phenoxy-methyl-pyperidino)-propoxy)indol and salts and esters thereof

Info

Publication number
YU128883A
YU128883A YU01288/83A YU128883A YU128883A YU 128883 A YU128883 A YU 128883A YU 01288/83 A YU01288/83 A YU 01288/83A YU 128883 A YU128883 A YU 128883A YU 128883 A YU128883 A YU 128883A
Authority
YU
Yugoslavia
Prior art keywords
pyperidino
indol
propoxy
phenoxy
hydroxy
Prior art date
Application number
YU01288/83A
Other languages
English (en)
Inventor
W Kampe
W G Friebe
F Wiedemann
G Sponer
W Barsch
K Dietmann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19762651574 external-priority patent/DE2651574A1/de
Priority claimed from DE19772737630 external-priority patent/DE2737630A1/de
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of YU128883A publication Critical patent/YU128883A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU01288/83A 1976-11-12 1983-06-09 Process for preparing 4-(2-hydroxy-3-(4-phenoxy-methyl-pyperidino)-propoxy)indol and salts and esters thereof YU128883A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19762651574 DE2651574A1 (de) 1976-11-12 1976-11-12 Ein neues aminopropanol-derivat und verfahren zu dessen herstellung
DE19772737630 DE2737630A1 (de) 1977-08-20 1977-08-20 Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
YU128883A true YU128883A (en) 1984-04-30

Family

ID=25771134

Family Applications (3)

Application Number Title Priority Date Filing Date
YU02664/77A YU266477A (en) 1976-11-12 1977-11-07 Process for preparing amino propanols and salts thereof
YU01288/83A YU128883A (en) 1976-11-12 1983-06-09 Process for preparing 4-(2-hydroxy-3-(4-phenoxy-methyl-pyperidino)-propoxy)indol and salts and esters thereof
YU01289/83A YU128983A (en) 1976-11-12 1983-06-09 Process for preparing 4-(2-hydroxy-3-(4-phenoxy-methyl-pyperidino)-propoxy)indol and salts and esters thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
YU02664/77A YU266477A (en) 1976-11-12 1977-11-07 Process for preparing amino propanols and salts thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
YU01289/83A YU128983A (en) 1976-11-12 1983-06-09 Process for preparing 4-(2-hydroxy-3-(4-phenoxy-methyl-pyperidino)-propoxy)indol and salts and esters thereof

Country Status (23)

Country Link
US (1) US4146630A (xx)
JP (1) JPS5363385A (xx)
AR (3) AR218643A1 (xx)
AT (1) AT361476B (xx)
AU (1) AU510284B2 (xx)
CA (1) CA1086740A (xx)
CH (3) CH636099A5 (xx)
CS (1) CS228106B2 (xx)
DD (1) DD133801A5 (xx)
DK (1) DK500677A (xx)
ES (2) ES472747A1 (xx)
FI (1) FI62077C (xx)
FR (1) FR2370744A1 (xx)
GB (1) GB1541547A (xx)
HU (1) HU177410B (xx)
IL (1) IL53323A (xx)
IT (1) IT1087490B (xx)
LU (1) LU78498A1 (xx)
NL (1) NL7712220A (xx)
PL (2) PL112683B1 (xx)
SE (1) SE7712720L (xx)
SU (2) SU826955A3 (xx)
YU (3) YU266477A (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
US4495352A (en) * 1979-02-13 1985-01-22 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
DE2905876A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2922084A1 (de) * 1979-05-31 1980-12-11 Boehringer Mannheim Gmbh Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
WO1985004580A1 (en) * 1984-04-09 1985-10-24 American Hospital Supply Corporation Pharmaceutical composition and method for treatment or prophylaxis of cardiac disorders
FR2574795B1 (fr) * 1984-12-18 1987-11-20 Ile De France Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide
US5789402A (en) * 1995-01-17 1998-08-04 Eli Lilly Company Compounds having effects on serotonin-related systems
US5614523A (en) * 1995-01-17 1997-03-25 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5627196A (en) * 1995-01-17 1997-05-06 Eli Lilly And Company Compounds having effects on serotonin-related systems
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
WO2010059393A1 (en) * 2008-10-30 2010-05-27 Janssen Pharmaceutica Nv Serotonin receptor modulators
WO2010059390A1 (en) 2008-10-30 2010-05-27 Janssen Pharmaceutica Nv Modulators of serotonin receptor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB925429A (en) * 1960-04-01 1963-05-08 Irwin Neisler & Co Indole derivatives
US3699123A (en) * 1970-03-24 1972-10-17 Sandoz Ltd 4-(3-amino-2-hydroxy-propoxy) indole derivatives
BE794333A (fr) * 1972-01-20 1973-07-19 Wyeth John & Brother Ltd Composes heterocycliques azotes therapeutiques
JPS517672B2 (xx) * 1972-04-13 1976-03-10
JPS6024100B2 (ja) * 1975-02-11 1985-06-11 ベーリンガー・マンハイム・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング アミノプロパノ−ル−誘導体の製法
DE2549568C3 (de) * 1975-11-05 1981-10-29 Bayer Ag, 5090 Leverkusen 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Also Published As

Publication number Publication date
CS228106B2 (en) 1984-05-14
JPS5363385A (en) 1978-06-06
SE7712720L (sv) 1978-05-13
PL110782B1 (en) 1980-07-31
CH643554A5 (de) 1984-06-15
ES472747A1 (es) 1979-02-16
AT361476B (de) 1981-03-10
FR2370744B1 (xx) 1981-06-12
IL53323A0 (en) 1978-01-31
DK500677A (da) 1978-05-13
AR218643A1 (es) 1980-06-30
PL112683B1 (en) 1980-10-31
AU3046677A (en) 1979-05-17
YU128983A (en) 1984-04-30
LU78498A1 (xx) 1979-02-02
AU510284B2 (en) 1980-06-19
CH639086A5 (de) 1983-10-31
PL201997A1 (pl) 1979-03-12
CA1086740A (en) 1980-09-30
FI62077C (fi) 1982-11-10
GB1541547A (en) 1979-03-07
FR2370744A1 (fr) 1978-06-09
ES472746A1 (es) 1979-02-16
SU826955A3 (ru) 1981-04-30
SU890975A3 (ru) 1981-12-15
US4146630A (en) 1979-03-27
AR221081A1 (es) 1980-12-30
FI773346A (fi) 1978-05-13
CH636099A5 (de) 1983-05-13
AR221868A1 (es) 1981-03-31
IL53323A (en) 1981-12-31
YU266477A (en) 1984-02-29
JPS6341910B2 (xx) 1988-08-19
NL7712220A (nl) 1978-05-17
FI62077B (fi) 1982-07-30
ATA808277A (de) 1980-08-15
IT1087490B (it) 1985-06-04
DD133801A5 (de) 1979-01-24
HU177410B (en) 1981-10-28

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