IL53323A - 1-(4-phenoxymethylpiperidino)-2-hydroxy-3-(indolyl(indazolyl,benzimidazolyl or benzotriazolyl)oxy)propanes,their preparation and pharmaceutical compositions containing them - Google Patents
1-(4-phenoxymethylpiperidino)-2-hydroxy-3-(indolyl(indazolyl,benzimidazolyl or benzotriazolyl)oxy)propanes,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL53323A IL53323A IL53323A IL5332377A IL53323A IL 53323 A IL53323 A IL 53323A IL 53323 A IL53323 A IL 53323A IL 5332377 A IL5332377 A IL 5332377A IL 53323 A IL53323 A IL 53323A
- Authority
- IL
- Israel
- Prior art keywords
- phenoxymethylpiperidino
- propanes
- benzotriazolyl
- indazolyl
- benzimidazolyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19762651574 DE2651574A1 (de) | 1976-11-12 | 1976-11-12 | Ein neues aminopropanol-derivat und verfahren zu dessen herstellung |
DE19772737630 DE2737630A1 (de) | 1977-08-20 | 1977-08-20 | Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
IL53323A0 IL53323A0 (en) | 1978-01-31 |
IL53323A true IL53323A (en) | 1981-12-31 |
Family
ID=25771134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL53323A IL53323A (en) | 1976-11-12 | 1977-11-07 | 1-(4-phenoxymethylpiperidino)-2-hydroxy-3-(indolyl(indazolyl,benzimidazolyl or benzotriazolyl)oxy)propanes,their preparation and pharmaceutical compositions containing them |
Country Status (23)
Country | Link |
---|---|
US (1) | US4146630A (xx) |
JP (1) | JPS5363385A (xx) |
AR (3) | AR218643A1 (xx) |
AT (1) | AT361476B (xx) |
AU (1) | AU510284B2 (xx) |
CA (1) | CA1086740A (xx) |
CH (3) | CH636099A5 (xx) |
CS (1) | CS228106B2 (xx) |
DD (1) | DD133801A5 (xx) |
DK (1) | DK500677A (xx) |
ES (2) | ES472747A1 (xx) |
FI (1) | FI62077C (xx) |
FR (1) | FR2370744A1 (xx) |
GB (1) | GB1541547A (xx) |
HU (1) | HU177410B (xx) |
IL (1) | IL53323A (xx) |
IT (1) | IT1087490B (xx) |
LU (1) | LU78498A1 (xx) |
NL (1) | NL7712220A (xx) |
PL (2) | PL112683B1 (xx) |
SE (1) | SE7712720L (xx) |
SU (2) | SU826955A3 (xx) |
YU (3) | YU266477A (xx) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4314943A (en) * | 1977-07-13 | 1982-02-09 | Mead Johnson & Company | Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols |
US4495352A (en) * | 1979-02-13 | 1985-01-22 | Mead Johnson & Company | Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols |
DE2905876A1 (de) * | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE2922084A1 (de) * | 1979-05-31 | 1980-12-11 | Boehringer Mannheim Gmbh | Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3200304A1 (de) * | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
WO1985004580A1 (en) * | 1984-04-09 | 1985-10-24 | American Hospital Supply Corporation | Pharmaceutical composition and method for treatment or prophylaxis of cardiac disorders |
FR2574795B1 (fr) * | 1984-12-18 | 1987-11-20 | Ile De France | Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide |
US5789402A (en) * | 1995-01-17 | 1998-08-04 | Eli Lilly Company | Compounds having effects on serotonin-related systems |
US5614523A (en) * | 1995-01-17 | 1997-03-25 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
US5576321A (en) * | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
US5741789A (en) | 1995-01-17 | 1998-04-21 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
US5627196A (en) * | 1995-01-17 | 1997-05-06 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
ZA9610736B (en) * | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
WO2010059393A1 (en) * | 2008-10-30 | 2010-05-27 | Janssen Pharmaceutica Nv | Serotonin receptor modulators |
WO2010059390A1 (en) | 2008-10-30 | 2010-05-27 | Janssen Pharmaceutica Nv | Modulators of serotonin receptor |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB925429A (en) * | 1960-04-01 | 1963-05-08 | Irwin Neisler & Co | Indole derivatives |
US3699123A (en) * | 1970-03-24 | 1972-10-17 | Sandoz Ltd | 4-(3-amino-2-hydroxy-propoxy) indole derivatives |
BE794333A (fr) * | 1972-01-20 | 1973-07-19 | Wyeth John & Brother Ltd | Composes heterocycliques azotes therapeutiques |
JPS517672B2 (xx) * | 1972-04-13 | 1976-03-10 | ||
JPS6024100B2 (ja) * | 1975-02-11 | 1985-06-11 | ベーリンガー・マンハイム・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | アミノプロパノ−ル−誘導体の製法 |
DE2549568C3 (de) * | 1975-11-05 | 1981-10-29 | Bayer Ag, 5090 Leverkusen | 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel |
-
1977
- 1977-10-27 US US05/846,057 patent/US4146630A/en not_active Expired - Lifetime
- 1977-11-07 YU YU02664/77A patent/YU266477A/xx unknown
- 1977-11-07 IL IL53323A patent/IL53323A/xx unknown
- 1977-11-07 AR AR269873A patent/AR218643A1/es active
- 1977-11-07 NL NL7712220A patent/NL7712220A/xx not_active Application Discontinuation
- 1977-11-08 FI FI773346A patent/FI62077C/fi not_active IP Right Cessation
- 1977-11-08 CS CS777291A patent/CS228106B2/cs unknown
- 1977-11-08 AU AU30466/77A patent/AU510284B2/en not_active Expired
- 1977-11-08 DD DD7700201951A patent/DD133801A5/xx unknown
- 1977-11-08 IT IT29456/77A patent/IT1087490B/it active
- 1977-11-08 GB GB46415/77A patent/GB1541547A/en not_active Expired
- 1977-11-09 PL PL1977213346A patent/PL112683B1/pl unknown
- 1977-11-09 PL PL1977201997A patent/PL110782B1/pl not_active IP Right Cessation
- 1977-11-09 CA CA290,495A patent/CA1086740A/en not_active Expired
- 1977-11-09 CH CH1367177A patent/CH636099A5/de not_active IP Right Cessation
- 1977-11-10 SE SE7712720A patent/SE7712720L/xx not_active Application Discontinuation
- 1977-11-10 FR FR7733907A patent/FR2370744A1/fr active Granted
- 1977-11-10 HU HU77BO1689A patent/HU177410B/hu unknown
- 1977-11-11 JP JP13559177A patent/JPS5363385A/ja active Granted
- 1977-11-11 AT AT808277A patent/AT361476B/de active
- 1977-11-11 DK DK500677A patent/DK500677A/da not_active Application Discontinuation
- 1977-11-11 LU LU7778498A patent/LU78498A1/xx unknown
-
1978
- 1978-08-22 ES ES472747A patent/ES472747A1/es not_active Expired
- 1978-08-22 ES ES472746A patent/ES472746A1/es not_active Expired
- 1978-10-20 SU SU782674802A patent/SU826955A3/ru active
- 1978-10-20 SU SU782675553A patent/SU890975A3/ru active
-
1979
- 1979-02-28 AR AR275655A patent/AR221868A1/es active
- 1979-02-28 AR AR275657A patent/AR221081A1/es active
-
1982
- 1982-06-14 CH CH367682A patent/CH639086A5/de not_active IP Right Cessation
-
1983
- 1983-05-02 CH CH233783A patent/CH643554A5/de not_active IP Right Cessation
- 1983-06-09 YU YU01288/83A patent/YU128883A/xx unknown
- 1983-06-09 YU YU01289/83A patent/YU128983A/xx unknown
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