YU108381A - Process for obtaining 2-bromo-6-fluoro-pregna-1,4-diene-3,20-dione-21-estra-17,21-cyclic ketals and acetals - Google Patents

Process for obtaining 2-bromo-6-fluoro-pregna-1,4-diene-3,20-dione-21-estra-17,21-cyclic ketals and acetals

Info

Publication number
YU108381A
YU108381A YU01083/81A YU108381A YU108381A YU 108381 A YU108381 A YU 108381A YU 01083/81 A YU01083/81 A YU 01083/81A YU 108381 A YU108381 A YU 108381A YU 108381 A YU108381 A YU 108381A
Authority
YU
Yugoslavia
Prior art keywords
pregna
estra
acetals
dione
diene
Prior art date
Application number
YU01083/81A
Other languages
English (en)
Inventor
M Riva
L Toscano
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Publication of YU108381A publication Critical patent/YU108381A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
YU01083/81A 1974-02-27 1981-04-27 Process for obtaining 2-bromo-6-fluoro-pregna-1,4-diene-3,20-dione-21-estra-17,21-cyclic ketals and acetals YU108381A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8928/74A GB1499822A (en) 1974-02-27 1974-02-27 2-bromo-6beta-fluoropregna-1,4-diene-3,20-diones
GB2998474 1974-07-05
GB3294574 1974-07-25
GB4998274 1974-11-19

Publications (1)

Publication Number Publication Date
YU108381A true YU108381A (en) 1982-02-28

Family

ID=27447687

Family Applications (3)

Application Number Title Priority Date Filing Date
YU01083/81A YU108381A (en) 1974-02-27 1981-04-27 Process for obtaining 2-bromo-6-fluoro-pregna-1,4-diene-3,20-dione-21-estra-17,21-cyclic ketals and acetals
YU01084/81A YU108481A (en) 1974-02-27 1981-04-27 Process for obtaning 2-bromo-6 beta-fluoro-pregna-1,4-diene-3,20-dione-21-estra-16,17-cyclic ketals and acetals
YU01082/81A YU108281A (en) 1974-02-27 1981-04-27 Process for obtaining 2-bromo-6 beta-fluoro-pregna-1,4-diene3,20-dione-21-estra-16,17-alcohols or esters

Family Applications After (2)

Application Number Title Priority Date Filing Date
YU01084/81A YU108481A (en) 1974-02-27 1981-04-27 Process for obtaning 2-bromo-6 beta-fluoro-pregna-1,4-diene-3,20-dione-21-estra-16,17-cyclic ketals and acetals
YU01082/81A YU108281A (en) 1974-02-27 1981-04-27 Process for obtaining 2-bromo-6 beta-fluoro-pregna-1,4-diene3,20-dione-21-estra-16,17-alcohols or esters

Country Status (18)

Country Link
JP (1) JPS5614677B2 (de)
AR (1) AR218601A1 (de)
BE (1) BE826030A (de)
CA (1) CA1064476A (de)
CH (1) CH608243A5 (de)
DE (3) DE2508136C3 (de)
DK (1) DK144068C (de)
ES (3) ES435067A1 (de)
FI (1) FI56188C (de)
FR (1) FR2261776B1 (de)
GB (1) GB1499822A (de)
IE (1) IE42112B1 (de)
LU (1) LU71908A1 (de)
NO (1) NO144527C (de)
NZ (1) NZ176716A (de)
RO (1) RO78881A (de)
SE (1) SE410736B (de)
YU (3) YU108381A (de)

Also Published As

Publication number Publication date
NZ176716A (en) 1978-07-10
YU108481A (en) 1982-02-28
JPS5614677B2 (de) 1981-04-06
DE2533377C3 (de) 1979-08-02
ES455934A1 (es) 1978-05-01
SE410736B (sv) 1979-10-29
DE2533323A1 (de) 1976-02-12
FR2261776B1 (de) 1978-07-21
FI56188B (fi) 1979-08-31
GB1499822A (en) 1978-02-01
DK144068C (da) 1982-05-03
JPS50126652A (de) 1975-10-04
NO750633L (de) 1975-08-28
BE826030A (fr) 1975-06-16
DK61575A (de) 1975-10-27
DK144068B (da) 1981-11-30
NO144527B (no) 1981-06-09
AR218601A1 (es) 1980-06-30
DE2508136B2 (de) 1978-11-02
NO144527C (no) 1981-09-23
FR2261776A1 (de) 1975-09-19
IE42112L (en) 1975-08-27
DE2533323C3 (de) 1979-07-12
IE42112B1 (en) 1980-06-04
DE2533377B2 (de) 1978-11-16
SE7502146L (de) 1975-08-28
CA1064476A (en) 1979-10-16
FI750537A (de) 1975-08-28
DE2533377A1 (de) 1976-02-05
DE2508136C3 (de) 1979-06-21
DE2533323B2 (de) 1978-11-16
RO78881A (ro) 1982-07-06
FI56188C (fi) 1979-12-10
DE2508136A1 (de) 1975-10-30
LU71908A1 (de) 1975-06-24
YU108281A (en) 1982-02-28
CH608243A5 (en) 1978-12-29
ES455933A1 (es) 1978-05-01
ES435067A1 (es) 1977-07-01

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