AR218601A1 - Un procedimiento para la preparacion de 2-bromo-6 beta-fluoro-9 alfa-fluo-11 beta,17,21-trihidroxi-pregna-1,4-dieno-3,20-diona y de sus esteres 17,21,alquilortoester 17,21 y acetales o cetales ciclicos 17,21 - Google Patents

Un procedimiento para la preparacion de 2-bromo-6 beta-fluoro-9 alfa-fluo-11 beta,17,21-trihidroxi-pregna-1,4-dieno-3,20-diona y de sus esteres 17,21,alquilortoester 17,21 y acetales o cetales ciclicos 17,21

Info

Publication number
AR218601A1
AR218601A1 AR257732A AR25773275A AR218601A1 AR 218601 A1 AR218601 A1 AR 218601A1 AR 257732 A AR257732 A AR 257732A AR 25773275 A AR25773275 A AR 25773275A AR 218601 A1 AR218601 A1 AR 218601A1
Authority
AR
Argentina
Prior art keywords
beta
trihidroxi
alkylortoester
cetals
diona
Prior art date
Application number
AR257732A
Other languages
English (en)
Spanish (es)
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Application granted granted Critical
Publication of AR218601A1 publication Critical patent/AR218601A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0092Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AR257732A 1974-02-27 1975-02-24 Un procedimiento para la preparacion de 2-bromo-6 beta-fluoro-9 alfa-fluo-11 beta,17,21-trihidroxi-pregna-1,4-dieno-3,20-diona y de sus esteres 17,21,alquilortoester 17,21 y acetales o cetales ciclicos 17,21 AR218601A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8928/74A GB1499822A (en) 1974-02-27 1974-02-27 2-bromo-6beta-fluoropregna-1,4-diene-3,20-diones
GB2998474 1974-07-05
GB3294574 1974-07-25
GB4998274 1974-11-19

Publications (1)

Publication Number Publication Date
AR218601A1 true AR218601A1 (es) 1980-06-30

Family

ID=27447687

Family Applications (1)

Application Number Title Priority Date Filing Date
AR257732A AR218601A1 (es) 1974-02-27 1975-02-24 Un procedimiento para la preparacion de 2-bromo-6 beta-fluoro-9 alfa-fluo-11 beta,17,21-trihidroxi-pregna-1,4-dieno-3,20-diona y de sus esteres 17,21,alquilortoester 17,21 y acetales o cetales ciclicos 17,21

Country Status (18)

Country Link
JP (1) JPS5614677B2 (de)
AR (1) AR218601A1 (de)
BE (1) BE826030A (de)
CA (1) CA1064476A (de)
CH (1) CH608243A5 (de)
DE (3) DE2508136C3 (de)
DK (1) DK144068C (de)
ES (3) ES435067A1 (de)
FI (1) FI56188C (de)
FR (1) FR2261776B1 (de)
GB (1) GB1499822A (de)
IE (1) IE42112B1 (de)
LU (1) LU71908A1 (de)
NO (1) NO144527C (de)
NZ (1) NZ176716A (de)
RO (1) RO78881A (de)
SE (1) SE410736B (de)
YU (3) YU108481A (de)

Also Published As

Publication number Publication date
DE2533377A1 (de) 1976-02-05
FI56188B (fi) 1979-08-31
NO144527C (no) 1981-09-23
CA1064476A (en) 1979-10-16
DK144068B (da) 1981-11-30
FI56188C (fi) 1979-12-10
NO750633L (de) 1975-08-28
ES455934A1 (es) 1978-05-01
FR2261776B1 (de) 1978-07-21
YU108381A (en) 1982-02-28
ES455933A1 (es) 1978-05-01
IE42112B1 (en) 1980-06-04
FR2261776A1 (de) 1975-09-19
IE42112L (en) 1975-08-27
DK61575A (de) 1975-10-27
ES435067A1 (es) 1977-07-01
JPS5614677B2 (de) 1981-04-06
SE7502146L (de) 1975-08-28
GB1499822A (en) 1978-02-01
DE2533377C3 (de) 1979-08-02
SE410736B (sv) 1979-10-29
YU108281A (en) 1982-02-28
BE826030A (fr) 1975-06-16
FI750537A (de) 1975-08-28
NO144527B (no) 1981-06-09
DE2508136A1 (de) 1975-10-30
DE2508136C3 (de) 1979-06-21
DK144068C (da) 1982-05-03
NZ176716A (en) 1978-07-10
CH608243A5 (en) 1978-12-29
DE2533377B2 (de) 1978-11-16
DE2508136B2 (de) 1978-11-02
DE2533323A1 (de) 1976-02-12
YU108481A (en) 1982-02-28
DE2533323C3 (de) 1979-07-12
JPS50126652A (de) 1975-10-04
DE2533323B2 (de) 1978-11-16
RO78881A (ro) 1982-07-06
LU71908A1 (de) 1975-06-24

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