WO2023123799A1 - 一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法 - Google Patents

一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法 Download PDF

Info

Publication number
WO2023123799A1
WO2023123799A1 PCT/CN2022/091417 CN2022091417W WO2023123799A1 WO 2023123799 A1 WO2023123799 A1 WO 2023123799A1 CN 2022091417 W CN2022091417 W CN 2022091417W WO 2023123799 A1 WO2023123799 A1 WO 2023123799A1
Authority
WO
WIPO (PCT)
Prior art keywords
sterilization
buffer
control valve
sterilizing
cabin
Prior art date
Application number
PCT/CN2022/091417
Other languages
English (en)
French (fr)
Inventor
孙金虎
黄勤
鲁登波
杨云
李祚云
常相辉
刘其军
刘霞
刘勇
Original Assignee
老肯医疗科技股份有限公司
西南交通大学
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 老肯医疗科技股份有限公司, 西南交通大学 filed Critical 老肯医疗科技股份有限公司
Publication of WO2023123799A1 publication Critical patent/WO2023123799A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/14—Plasma, i.e. ionised gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/24—Apparatus using programmed or automatic operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26—Accessories or devices or components used for biocidal treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2101/00—Chemical composition of materials used in disinfecting, sterilising or deodorising

Definitions

  • the invention relates to the field of medical device manufacturing, in particular to a high-efficiency sterilizing hydrogen peroxide plasma sterilizer and a sterilizing method.
  • the purpose of the present invention is to overcome the deficiencies of the prior art, to provide a high-efficiency sterilized hydrogen peroxide plasma sterilizer and a sterilization method, including a sterilizer equipped with a vacuum pump, an evaporator, a sterilization chamber and a control system
  • the main body also includes a buffer cabin with an accommodating chamber, the buffer cabin communicates with the sterilization cabin through the first pipeline and the second pipeline; the first air pump and the first control valve are installed on the first pipeline, and the second pipeline is installed with The second control valve, the first control valve is used to open or close the first pipeline, the second control valve is used to open or close the second pipeline; the first air pump, the first control valve and the second control valve are all electrically connected to the control system connect.
  • All the sterilizing gas in the sterilization chamber is pumped into the buffer chamber by the first air pump, and the sterilization chamber is in a vacuum state. After the sterilizing gas is mixed in the buffer chamber, the second air pump is turned on, and the purified The sterilizing gas is filled into the sterilization chamber again, so that the inside of the endoscope and other luminal instruments is filled with a high concentration of sterilizing gas, and the above process is repeated, thereby sterilizing the luminal instruments, which greatly speeds up the process. sterilization efficiency.
  • a high-efficiency sterilizing hydrogen peroxide plasma sterilizer including a sterilizer body equipped with a vacuum pump, an evaporator, a sterilization cabin and a control system, and a buffer cabin with an accommodating cavity, the buffer cabin passes through the first The conduit and the second conduit communicate with the sterilization chamber.
  • a first air pump and a first control valve are installed on the first pipeline, and a second control valve is installed on the second pipeline.
  • the first control valve is used to open or close the first pipeline
  • the second control valve is used to open or close the second pipeline. Two pipes.
  • the first air pump, the first control valve and the second control valve are all electrically connected to the control system.
  • a concentration detection device is provided on the buffer compartment, and one end of the concentration detection device penetrates the side wall of the buffer compartment and extends into the accommodating cavity, and is connected to the side wall of the buffer compartment.
  • a heating device and a temperature detection device are arranged on the buffer compartment, the heating device is used for heating the buffer compartment, and the temperature detection device is used for detecting the temperature value in the accommodating chamber.
  • the concentration detecting device, the temperature detecting device and the heating device are all electrically connected with the control system.
  • the heating device is installed on the side wall of the buffer compartment, and the heating device includes a casing and a heating element installed in the casing, and a vent is opened on the casing.
  • a pressure detection device is also provided on the buffer cabin, the pressure detection device is connected with the control system, and the pressure detection device is used to detect the pressure value in the accommodation chamber.
  • a condensing device and a storage tank are provided on the buffer cabin, and the condensing device is installed on the side wall of the buffer cabin for cooling the sterilized gas; It is threadedly connected with the buffer cabin, and the storage tank is used to place the desiccant.
  • the condensing device includes at least one fan and at least one heat conduction element, and the fan is installed on the side wall of the buffer compartment through the heat conduction element.
  • a second air pump is installed on the second pipeline, and the second air pump is electrically connected with the control system.
  • a method for sterilizing a hydrogen peroxide plasma sterilizer characterized in that sterilizing based on the above-mentioned hydrogen peroxide plasma sterilizer includes the following steps.
  • Step 100 Put the endoscope and other lumen-type medical devices into the sterilization chamber, close the sterilization chamber, open the second control valve and start the sterilizer, and vacuum the sterilization chamber and the buffer chamber through the vacuum pump ; Then close the second control valve and send the sterilizing gas into the sterilizing cabin for sterilization.
  • Step 200 After the sterilizing gas enters the sterilizing chamber for a period of time, the first air pump and the first control valve are turned on through the control system, and the sterilizing gas in the sterilizing chamber is sent into the buffer chamber, and the sterilizing chamber is a vacuum state, close the first control valve and the first air pump.
  • Step 300 The condensing device is activated to cool down the sterilized gas in the buffer chamber, and the water vapor in the sterilized gas is condensed into liquid water.
  • Step 400 The control system controls the heating device to heat the sterilizing gas in the buffer chamber, and the temperature detection device detects the real-time temperature of the sterilizing gas.
  • Step 500 The concentration detection device detects the concentration of the sterilizing gas in the buffer compartment and transmits it to the control system for comparison with the preset threshold value. If the concentration of the sterilizing gas in the buffer compartment is greater than or equal to the threshold value, the control system controls the second control valve to open And start the second air pump, the sterilizing gas in the buffer cabin enters the sterilization cabin, then close the second control valve and the second air pump.
  • the control system controls the evaporator to fill a certain volume of sterilizing gas into the sterilization chamber, and then controls the second control valve to open, and the sterilizing gas in the buffer chamber enters the In the sterilization chamber, then close the second control valve and the second air pump.
  • Step 600 Repeat steps 100-500 until the sterilization work is completed.
  • step 400 the temperature reached by the heating device is 70°C-75°C.
  • the first air pump and the first control valve are opened, and the first air pump will The sterilizing gas in the sterilization chamber is pumped into the buffer chamber, and then the first air pump and the first control valve are closed.
  • the condensing device can cool down the sterilizing gas, condense the water vapor in the sterilizing gas into liquid water and store it at the bottom of the buffer compartment;
  • the detection device can detect the concentration value of the sterilization gas and transmit it to the control system.
  • the control system compares the concentration value with the preset threshold value. If the concentration value is less than the threshold value, the control system controls the evaporator to supply a certain amount of sterilization gas into the sterilization chamber to ensure the successful completion of the sterilization work. After repeating the above steps several times, after the internal sterilization of the lumen device is qualified, the sterilization work is completed. During the whole sterilization process, the lumen of the tube is always sterilized with a higher concentration of sterilizing gas, which greatly improves the sterilization efficiency and the sterilization effect.
  • Fig. 1 is a schematic structural view of a high-efficiency sterilizing hydrogen peroxide plasma sterilizer provided by the present invention.
  • Fig. 2 is a principle schematic diagram of a high-efficiency sterilizing hydrogen peroxide plasma sterilizer provided by the present invention.
  • Fig. 3 is a schematic structural diagram of the buffer compartment provided by the present invention.
  • Fig. 4 is a schematic diagram of the internal structure of the heating device provided by the present invention.
  • Fig. 5 is a flowchart of the sterilization method provided by the present invention.
  • Icons 100-sterilizer body; 101-sterilization cabin; 110-buffer cabin; 111-concentration detection device; 113-first pipeline; 117-first air pump; 119-first control valve; 130-second Pipeline; 133-second control valve; 135-second air pump; 150-heating device; 151-shell; 153-heating element; 155-temperature detection device; Device; 171-storage tank; 173-fan; 175-heat conduction element.
  • a kind of hydrogen peroxide plasma sterilizer of high-efficiency sterilization comprises the sterilizer body 100 that vacuum pump, evaporator, sterilization chamber 101 and control system are installed, also includes equipment There is a buffer chamber 110 with an accommodating chamber, and the buffer chamber 110 communicates with the sterilization chamber 101 through a first pipeline 113 and a second pipeline 130 ; a first air pump 117 and a first control valve 119 are installed on the first pipeline 113 .
  • the first control valve 119 is used to open or close the first pipe 113 .
  • a second control valve 133 is installed on the second pipeline 130 , and the second control valve 133 is used to open or close the second pipeline 130 .
  • the first air pump 117, the first control valve 119 and the second control valve 133 are all electrically connected to the control system.
  • the control system controls the second control valve 133 to open, the air in the sterilization chamber 101 and the buffer chamber 110 is extracted, and the sterilization chamber 101 and the buffer chamber 110 are both in a vacuum state, and then the control system controls the second control valve 133 to close, and the sterilizing gas in the evaporator enters the sterilization chamber 101, diffuses and adheres to the surface of the medical device, and then enters the interior of the lumen device for sterilization. Sterilize.
  • the control system controls the opening of the first control valve 119 and starts the first air pump 117
  • the sterilizing gas in the sterilization chamber 101 enters the buffer chamber 110 under the action of the pressure difference and the first air pump 117, and the control system controls the first control valve 119 to close.
  • the buffer chamber 110 is provided with A sterilant injection module, the sterilant injection module is used to inject hydrogen peroxide sterilant into the buffer compartment 110, after the sterilizing gas after the sterilant concentration drops enters the buffer compartment 110, the sterilant injection The module supplements and injects hydrogen peroxide sterilant into the buffer compartment 110.
  • the control system controls the second control valve 133 to open.
  • the sterilizing gas pours into the sterilization chamber 101 through the second pipeline 130, attaches to the surface of the medical device again and enters the interior of the lumen device for sterilization.
  • the sterilization work is completed. During the whole sterilization process, the interior of the lumen device is always sterilized with a higher concentration of sterilizing gas, which improves the sterilization effect of the sterilizer on the lumen device.
  • the volume of the buffer cabin 110 should be as small as possible smaller than the volume of the sterilization cabin 101, so as to ensure that most of the sterilizing gas in the buffer cabin 110 enters the sterilization cabin 101 . If the volume difference between the buffer chamber 110 and the sterilization chamber 101 is small, a second air pump 135 should be installed on the second pipeline, and the second air pump 135 is electrically connected to the control system. The remaining sterilizing gas in the buffer chamber 110 is pumped into the sterilization chamber 101 by the second air pump 135 to ensure the sterilization effect.
  • the sterilization gas is gaseous hydrogen peroxide.
  • the buffer compartment 110 is provided with a condensation device 170 and a storage tank 171 , the condensation device 170 includes at least one fan 173 and at least one heat conducting member 175 , and the fan 173 is installed in the buffer compartment 110 through the heat conducting member 175
  • the heat in the buffer compartment 110 can be quickly transferred to the body of the heat conduction element 175, and the temperature of the heat conduction element 175 is cooled by the rotation of the fan 173, so that the condensing device 170 can cool down the sterilization gas.
  • the sterilizing gas entering the buffer chamber 110 will be partially decomposed into water vapor and oxygen during the sterilization process in the sterilizing chamber 101, and the sterilizing gas can be cooled by the condensing device 170 to condense the water vapor into liquid water , and keep it at the bottom of the buffer compartment 110, thereby purifying the sterilizing gas.
  • the upper end of the storage tank 171 is installed on the bottom surface of the buffer cabin 110 and communicates with the cavity of the buffer cabin 110, the storage tank 171 is screwed to the buffer cabin 110, the storage tank 171 is used to place a desiccant, and the desiccant can absorb the buffer cabin
  • the liquid water at the bottom of 110 keeps the interior of the buffer compartment 110 dry, and when the desiccant is saturated, the side cover 132 can be opened to replace the desiccant.
  • a heating device 150 and a temperature detection device 155 are installed on the side wall of the buffer compartment 110.
  • the heating device 150 includes a casing 151 and a heating element 153 installed in the casing 151.
  • the casing of the heating element 153 is provided with a vent 157 for heating
  • the heating method of the piece 153 is steam heating or electric heating. Both the heating element 153 and the temperature detection device 155 are electrically connected to the control system.
  • the control system controls the heating device 153 to heat the buffer compartment 110 to keep the temperature of the sterilizing gas at about 75°C and keep the hydrogen peroxide Gas state, to avoid the liquefied hydrogen peroxide entering the sterilization chamber 101 and affecting the sterilization effect.
  • the temperature detection device 155 is used to detect the temperature value in the storage cavity. When the temperature value in the storage cavity is greater than the preset temperature value, the control system automatically disconnects the heating device 150. When the temperature value in the storage cavity is lower than the preset temperature value , the control system starts the heating device 150 automatically. Therefore, the temperature in the accommodating cavity is kept at a constant temperature state, and the hydrogen peroxide is decomposed into oxygen and water to prevent the sterilization effect from being too high.
  • a pressure detection device 159 is also provided on the buffer cabin 110, the pressure detection device 159 is a pressure sensor, the pressure detection device 159 is electrically connected to the control system, and the pressure detection device 159 is used to detect the pressure value in the containing chamber to avoid heating When the device is heated, the pressure is too high, causing damage to the buffer chamber 110 . If the pressure in the containing chamber is too high, the control system will control the second control valve to open.
  • a concentration detection device 111 is provided on the buffer compartment 110, and the concentration detection device 111 is a hydrogen peroxide concentration detector.
  • One end of the concentration detection device 111 penetrates the side wall of the buffer compartment 110 into the accommodating cavity, and is connected to the side wall of the buffer compartment 110 .
  • the concentration detection device 111 is electrically connected to the control system, and the concentration detection device 111 transmits the measured concentration value to the control system, and the control system calculates the volume of hydrogen peroxide according to a preset formula, and then compares it with a preset threshold.
  • the control system controls the second control valve 133 to open, after the hydrogen peroxide gas in the buffer cabin 110 enters the sterilization cabin 101, close the second control valve 133, and then start the evaporation
  • the device replenishes a certain amount of hydrogen peroxide gas in the sterilization chamber 101 to ensure that the sterilization work is carried out.
  • the control system controls the second control valve 133 to open, and after the hydrogen peroxide gas in the buffer chamber 110 enters the sterilization chamber 101, close the second control valve 133 to continue the sterilization Work.
  • the sterilization method based on the above-mentioned high-efficiency sterilization hydrogen peroxide plasma sterilizer includes the following steps.
  • Step 100 put endoscope and other luminal medical instruments into the sterilization chamber 101, close the sterilization chamber 101, open the second control valve 133 and start the sterilizer, the control system controls the vacuum pump to sterilize the sterilization chamber 101 and The buffer compartment 110 is vacuumed. Then the control system controls the second control valve 133 to close, and then sends the sterilizing gas into the sterilizing chamber 101 for sterilization, so as to prevent the sterilizing gas from entering the buffer chamber 110 .
  • Step 200 After the sterilizing gas enters the sterilizing chamber 101 for a period of time, that is, after the concentration of the sterilizing gas inside the lumen device drops significantly, the first air pump 117 and the first control valve 119 are turned on through the control system to sterilize
  • the sterilizing gas in the cabin 101 is sent into the buffer cabin 110, and when the sterilization cabin 101 is in a vacuum state, the first control valve 119 and the first air pump 117 are closed, and the sterilizing gas with a high concentration is injected into the buffer cabin 110.
  • the low-concentration sterilizing gas and the high-concentration sterilizing gas are fully mixed in the buffer chamber 110 to obtain a uniformly concentrated sterilizing gas.
  • Step 300 The condensing device 170 starts to cool down the sterilizing gas in the buffer compartment 110, and the water vapor in the sterilizing gas condenses into liquid water;
  • the sterilizing gas is gaseous hydrogen peroxide, which is During the sterilization process of cabin 101, part of the hydrogen peroxide gas is decomposed into oxygen and water vapor, which reduces the concentration of hydrogen peroxide, and the mixture of hydrogen peroxide and water vapor is cooled to a certain extent by the condensing device, which can make the water vapor Condensed into liquid water and separated from the hydrogen peroxide gas, so as to purify the hydrogen peroxide gas and improve the subsequent sterilization effect.
  • Step 400 The control system manipulates the heating device 150 to heat the sterilizing gas in the buffer compartment 110, the temperature detection device detects the real-time temperature of the sterilizing gas, and the hydrogen peroxide gas is heated and discharged through the cooperation of the heating device 150 and the temperature detection device 155. Keep it in a constant temperature state to avoid continuous cooling of the hydrogen peroxide gas from gaseous state to liquid state and accumulate at the bottom of the buffer chamber 110, resulting in the reduction of sterilizing gas entering the sterilization chamber 101 and affecting the sterilization effect.
  • the heating device 150 keeps the temperature of the hydrogen peroxide at 70° C.-75° C., which is the optimum temperature state.
  • Step 500 The concentration detection device 111 detects the concentration of the sterilizing gas in the buffer compartment 110 and transmits it to the control system for comparison with a preset threshold.
  • the threshold here needs to be determined according to factors such as the volume of the buffer chamber 110, the time for the sterilization gas to be sterilized in the sterilization chamber 101, and the decomposition rate of the sterilization gas, and there are multiple thresholds. Each time within 110 corresponds to a threshold, the more the number of entries, the smaller the threshold.
  • the volume of the chamber 110 is used to calculate the concentration of the sterilization gas entering the buffer chamber 110 for the first time, that is, the first threshold. Based on the above calculation process, multiple thresholds are calculated. Assuming that the time interval for the sterilizing gas to enter the buffer compartment 110 is constant, the threshold is roughly inversely proportional to the number of times of entry.
  • the control system will control the second control valve 133 to open and start the second air pump 135, and the sterilizing gas in the buffer cabin 110 will completely enter the sterilization cabin 101, Then the second control valve 133 and the second air pump 135 are closed, and the sterilizing gas adheres to the surface of the medical device and enters the interior of the lumen device for sterilization.
  • the control system controls the evaporator to fill a certain volume of sterilizing gas into the sterilization cabin 101, and then controls the second control valve 133 to open, and the sterilizing gas in the buffer cabin 110
  • the sterilizing gas enters the sterilizing chamber 101, then the second control valve 133 and the second air pump 135 are closed, and the sterilizing gas is replenished through the evaporator so that the sterilizing gas in the sterilizing chamber 101 reaches the desired concentration.
  • Step 600 Repeat steps 100-500 until the sterilization work is completed.

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

本发明公开了一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法，灭菌器包括安装有真空泵、蒸发器、灭菌舱和控制系统的灭菌器本体，还包括设有容纳腔的缓存舱，缓存舱通过第一管道和第二管道与灭菌舱连通；第一管道上安装有第一空气泵和第一控制阀，第二管道上安装有第二控制阀，第一控制阀用于打开或关闭第一管道，第二控制阀用于打开或关闭第二管道；第一空气泵、第一控制阀和第二控制阀均与控制系统电连接。本发明将浓度值与预设阈值进行比较，如浓度值小于阈值，则控制系统操控蒸发器向灭菌舱内补充一定量的灭菌气体，以保证灭菌工作顺利完成；在整个灭菌过程中，管腔内始终以较高浓度的灭菌气体进行灭菌，大大提高了灭菌效率和灭菌效果。

Description

一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法 技术领域
本发明涉及医疗器械制造领域，具体涉及一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法。
 背景技术
现在医院普遍采用过氧化氢等离子体灭菌器对医疗器械进行灭菌工作。过氧化氢等离子体灭菌器的工作原理是将过氧化氢液体汽化后导入到灭菌器的灭菌舱中，在电极网的作用下使过氧化氢分子发生电离反应，通过将等离子体状态的过氧化氢附着在医疗器械的表面，使其与医疗器械表面的微生物细胞壁、酵素发生分解反应, 破坏微生物细胞的脱氧核糖核酸等遗传物质, 从而达到杀灭微生物的效果。
现有的过氧化氢等离子体灭菌器对手术刀、手术钳和烧杯等医疗器械有很好的灭菌效果，但对内窥镜等管腔类医疗器械的灭菌效果并不理想。灭菌舱内管腔类医疗器械外围的灭菌气体通过扩散作用能够较快的得到补充，使灭菌气体的浓度维持在良好水平。但对于管腔内的部位，由于灭菌气体不能及时扩散而造成管腔内的灭菌气体浓度下降明显，仅靠扩散作用对管腔内部进行灭菌需要消耗很长时间，灭菌效率大大降低。
 技术问题
本发明的目的在于克服现有技术的不足，提供一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法，包括安装有真空泵、蒸发器、灭菌舱和控制系统的灭菌器本体，还包括设有容纳腔的缓存舱，缓存舱通过第一管道和第二管道与灭菌舱连通；第一管道上安装有第一空气泵和第一控制阀，第二管道上安装有第二控制阀，第一控制阀用于打开或关闭第一管道，第二控制阀用于打开或关闭第二管道；第一空气泵、第一控制阀和第二控制阀均与控制系统电连接。通过第一空气泵将灭菌舱内的灭菌气体全部抽取到缓存舱内，灭菌舱内为真空状态，灭菌气体在缓存舱内混合之后，然后打开第二空气泵，将提纯后的灭菌气体再次充入灭菌舱内，从而使内窥镜等管腔类器械的内部充入浓度较高的灭菌气体，反复上述过程，从而对管腔类器械进行灭菌，大大加快了灭菌效率。
 技术解决方案
在此处键入技术解决方案描述段落。一种高效率灭菌的过氧化氢等离子灭菌器，包括安装有真空泵、蒸发器、灭菌舱和控制系统的灭菌器本体，还包括设有容纳腔的缓存舱，缓存舱通过第一管道和第二管道与灭菌舱连通。
第一管道上安装有第一空气泵和第一控制阀，第二管道上安装有第二控制阀，第一控制阀用于打开或关闭第一管道，第二控制阀用于打开或关闭第二管道。
第一空气泵、第一控制阀和第二控制阀均与控制系统电连接。
进一步的，在缓存舱上设置有浓度检测装置，浓度检测装置的一端贯穿缓存舱的侧壁伸入到容纳腔内，且与缓存舱的侧壁连接。
在缓存舱上设置有加热装置和温度检测装置，加热装置用于对缓存舱进行加热，温度检测装置用于检测容纳腔内的温度值。
浓度检测装置、温度检测装置和加热装置均与控制系统电连接。
进一步的，加热装置安装在缓存舱的侧壁上，加热装置包括外壳和安装在外壳内的加热件，外壳上开设有通风口。
进一步的，在缓存舱上还设置有压力检测装置，压力检测装置与控制系统连接，压力检测装置用于检测容纳腔内的压力值。
进一步的，缓存舱上设置有冷凝装置和储存罐，冷凝装置安装在缓存舱的侧壁上，用于对灭菌气体进行降温；储存罐安装在缓存舱的底面且与容纳腔连通，储存罐与缓存舱螺纹连接，储存罐用于放置干燥剂。
进一步的，冷凝装置包括至少一个风扇和至少一个导热件，风扇通过导热件安装在缓存舱的侧壁上。
进一步的，第二管道上还安装有第二空气泵，第二空气泵与控制系统电连接。
一种过氧化氢等离子灭菌器的灭菌方法，其特征在于，基于上述过氧化氢等离子灭菌器进行灭菌，包括以下步骤。
步骤100：将内窥镜等管腔类医疗器械放入灭菌舱内，关闭灭菌舱后，打开第二控制阀并启动灭菌器，通过真空泵对灭菌舱和缓存舱进行抽真空工作；然后关闭第二控制阀，将灭菌气体送入灭菌舱进行灭菌。
步骤200：灭菌气体进入到灭菌舱一段时间后，通过控制系统打开第一空气泵和第一控制阀，将灭菌舱内的灭菌气体送入缓存舱内，灭菌舱内为真空状态时，关闭第一控制阀和第一空气泵。
步骤300：冷凝装置启动对缓存舱内的灭菌气体进行降温，灭菌气体中的水蒸气冷凝成液态水。
步骤400：控制系统操控加热装置对缓存舱内的灭菌气体进行加热，温度检测装置检测灭菌气体的实时温度。
步骤500：浓度检测装置检测缓存舱内的灭菌气体的浓度并传输给控制系统与预设阈值比较，如缓存舱内的灭菌气体浓度大于或等于阈值，则控制系统操控第二控制阀打开并启动第二空气泵，缓存舱内的灭菌气体进入到灭菌舱内，然后关闭第二控制阀和第二空气泵。
如缓存舱内的灭菌气体浓度小于阈值，则控制系统操控蒸发器向灭菌舱内充入一定体积的灭菌气体后，再操控第二控制阀打开，缓存舱内的灭菌气体进入到灭菌舱内，然后关闭第二控制阀和第二空气泵。
步骤600：重复步骤100-步骤500，直至灭菌工作完成。
进一步的，步骤400中，加热装置加热达到的温度值为70℃-75℃。
 有益效果
本发明所提供的一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法，在灭菌器灭菌一段时间后，打开第一空气泵和第一控制阀，第一空气泵将灭菌舱内的灭菌气体抽取至缓存舱内，然后关闭第一空气泵和第一控制阀。打开冷凝装置后，冷凝装置能够对灭菌气体进行降温，将灭菌气体中的水蒸气冷凝成液态水留存在缓存舱底部；再通过加热装置对灭菌气体进行加热使其保持气体状态，浓度检测装置能够检测灭菌气体的浓度值并传输给控制系统。然后打开第二控制阀和第二空气泵，在压差和第二空气泵作用下，缓存舱内的灭菌气体进入到灭菌舱内，再关闭第二控制阀和第二空气泵。控制系统将浓度值与预设阈值进行比较，如浓度值小于阈值，则控制系统操控蒸发器向灭菌舱内补充一定量的灭菌气体，以保证灭菌工作顺利完成。重复上述步骤几次后，管腔类器械内部灭菌合格后，灭菌工作完成。在整个灭菌过程中，管腔内始终以较高浓度的灭菌气体进行灭菌，大大提高了灭菌效率且提高了灭菌效果。
 附图说明
图1是本发明提供的一种高效率灭菌的过氧化氢等离子灭菌器的结构示意图。
图2是本发明提供的一种高效率灭菌的过氧化氢等离子灭菌器的原理示意图。
图3是本发明提供的缓存舱的结构示意图。
图4是本发明提供的加热装置的内部结构示意图。
图5是本发明提供的灭菌方法的流程图。
图标：100-灭菌器本体；101-灭菌舱；110-缓存舱；111-浓度检测装置；113-第一管道；117-第一空气泵；119-第一控制阀；130-第二管道；133-第二控制阀；135-第二空气泵；150-加热装置；151-外壳；153-加热件；155-温度检测装置；157-通风口；159-压力检测装置；170-冷凝装置；171-储存罐；173-风扇；175-导热件。
 本发明的最佳实施方式
本发明的最佳实施方式与下文描述的本发明的实施方式相同。
 本发明的实施方式
下面结合附图进一步详细描述本发明的技术方案，但本发明的保护范围不局限于以下所述。
请参考图1和图2所示，一种高效率灭菌的过氧化氢等离子灭菌器，包括安装有真空泵、蒸发器、灭菌舱101和控制系统的灭菌器本体100，还包括设有容纳腔的缓存舱110，缓存舱110通过第一管道113和第二管道130与灭菌舱101连通；第一管道113上安装有第一空气泵117和第一控制阀119。第一控制阀119用于打开或关闭第一管道113。第二管道130上安装有第二控制阀133，第二控制阀133用于打开或关闭第二管道130。第一空气泵117、第一控制阀119和第二控制阀133均与控制系统电连接。将医疗器械放入灭菌舱101后，启动灭菌器对医疗器械进行灭菌，控制系统操控第二控制阀133打开，灭菌舱101和缓存舱110内的空气被抽取，灭菌舱101和缓存舱110内均为真空状态，然后控制系统操控第二控制阀133关闭，蒸发器内的灭菌气体进入到灭菌舱101内扩散附着在医疗器械表面并进入到管腔类器械内部进行灭菌。灭菌一段时间后，灭菌舱101内的灭菌气体浓度下降，且管腔类器械内部的灭菌气体浓度下降明显，此时控制系统操控第一控制阀119打开且启动第一空气泵117，灭菌舱101内的灭菌气体在压差和第一空气泵117的作用下进入到缓存舱110内，控制系统操控第一控制阀119关闭，优选地，所述缓存舱110上设置有灭菌剂注入模块，所述灭菌剂注入模块用于向缓存舱110内注入过氧化氢灭菌剂，在灭菌剂浓度下降后的灭菌气体进入到缓存舱110后，灭菌剂注入模块则向缓存舱110内补充注入过氧化氢灭菌剂，待缓存舱110内的灭菌气体完全混合后，控制系统操控第二控制阀133打开，在压差作用下，缓存舱110内的灭菌气体通过第二管道130涌入灭菌舱101内，再次附着在医疗器械表面并进入到管腔类器械内部进行灭菌，反复几次上述过程后，对管腔类器械内腔的灭菌工作完成，整个灭菌过程中，管腔类器械内部始终以较高浓度的灭菌气体进行灭菌，提高了灭菌器对管腔类器械的灭菌效果。
需要说明的是，由于灭菌气体从缓存舱110进入到灭菌舱101内时，由于气压平衡，缓存舱110内的部分灭菌气体会留在缓存舱110内无法进入灭菌舱101内，所以在本实施方式中，在保证安全的情况下，缓存舱110的体积应尽可能的小于灭菌舱101的体积，以保证缓存舱110内的灭菌气体大部分进入到灭菌舱101内。如缓存舱110的体积与灭菌舱101的体积相差较小，应在第二管道上安装第二空气泵135，第二空气泵135与控制系统电连接。通过第二空气泵135将缓存舱110内剩余的灭菌气体抽取到灭菌舱101内，以保证灭菌效果。此外，灭菌气体为气态的过氧化氢。
请参考图3和图4所示，缓存舱110上设置有冷凝装置170和储存罐171，冷凝装置170包括至少一个风扇173和至少一个导热件175，风扇173通过导热件175安装在缓存舱110的侧壁上，导热件175能够将缓存舱110内的热量快速传导到导热件175本体上，通过风扇173转动对导热件175进行降温，从而使冷凝装置170对灭菌气体进行降温。进入到缓存舱110内的灭菌气体在灭菌舱101内灭菌的过程中会有部分分解成水蒸气和氧气，通过冷凝装置170对灭菌气体进行降温，能够将水蒸气冷凝成液态水，并使其保留在缓存舱110的底部，从而对灭菌气体进行提纯。
进一步的，储存罐171的上端安装在缓存舱110的底面且与缓存舱110的容纳腔连通，储存罐171与缓存舱110螺纹连接，储存罐171用于放置干燥剂，干燥剂能够吸附缓存舱110底部的液态水，使缓存舱110内部保持干燥，当干燥剂饱和时，可打开侧盖132更换干燥剂。
进一步的，缓存舱110的侧壁上安装有加热装置150和温度检测装置155，加热装置150包括外壳151和安装在外壳151内的加热件153，加热件153外壳上开设有通风口157，加热件153的加热方式为蒸汽加热或电加热。加热件153和温度检测装置155均与控制系统电连接。冷凝装置170对灭菌气体降温将水蒸气从灭菌气体中分离出之后，控制系统操控加热装置153对缓存舱110进行加热，使灭菌气体的温度保持在75℃左右，使过氧化氢保持气体状态，避免过氧化氢液化后进入灭菌舱101影响灭菌效果。温度检测装置155用于检测容纳腔内的温度值，当容纳腔内的温度值大于预设温度值时，控制系统自动断开加热装置150，当容纳腔内的温度值小于预设温度值时，控制系统自动启动加热装置150。从而使容纳腔内的温度处于恒温状态，避免温度过高，过氧化氢分解成氧气和水，无法起到灭菌效果。
进一步的，在缓存舱110上还设置有压力检测装置159，压力检测装置159为压力传感器，压力检测装置159与控制系统电连接，压力检测装置159用于检测容纳腔内的压力值，避免加热装置加热时，压强过大，对缓存舱110造成损坏。如容纳腔内压强过大，控制系统会操控第二控制阀开启。
进一步的，在缓存舱110上设置有浓度检测装置111，浓度检测装置111为过氧化氢浓度检测仪。浓度检测装置111的一端贯穿缓存舱110的侧壁伸入到容纳腔内，且与缓存舱110的侧壁连接。浓度检测装置111与控制系统电连接，浓度检测装置111将测得的浓度值传输给控制系统，控制系统根据预设公式计算出过氧化氢的体积，再与预设阈值比较。当过氧化氢的体积小于预设阈值时，控制系统控制第二控制阀133开启，缓存舱110内的过氧化氢气体进入到灭菌舱101内后，关闭第二控制阀133，然后开启蒸发器向灭菌舱101内补充一定量的过氧化氢气体，保证灭菌工作的进行。当过氧化氢的体积大于预设阈值时，控制系统控制第二控制阀133开启，缓存舱110内的过氧化氢气体进入到灭菌舱101内后，关闭第二控制阀133，继续灭菌工作。此处的预设阈值为多个，每次将灭菌气体抽取到缓存舱110内均会对应设置有一个预设阈值，预设阈值随灭菌器灭菌的时间变化，灭菌器灭菌时间越长，预设阈值越小。
请参考图所5示，基于上述高效率灭菌的过氧化氢等离子灭菌器的灭菌方法，包括以下步骤。
步骤100：将内窥镜等管腔类医疗器械放入灭菌舱101内，关闭灭菌舱101后，打开第二控制阀133并启动灭菌器，控制系统控制真空泵对灭菌舱101和缓存舱110进行抽真空工作。然后控制系统操控第二控制阀133关闭，再将灭菌气体送入灭菌舱101进行灭菌，避免灭菌气体进入到缓存舱110内。
步骤200：灭菌气体进入到灭菌舱101一段时间后，即管腔类器械内部的灭菌气体浓度明显下降之后，通过控制系统打开第一空气泵117和第一控制阀119，将灭菌舱101内的灭菌气体送入缓存舱110内，灭菌舱101内为真空状态时，关闭第一控制阀119和第一空气泵117，向缓存舱110注入浓度高的灭菌气体，浓度低的灭菌气体和浓度高的灭菌气体在缓存舱110内充分混合，得到浓度均匀的灭菌气体。
步骤300：冷凝装置170启动对缓存舱110内的灭菌气体进行降温，灭菌气体中的水蒸气冷凝成液态水；在本实施方式中灭菌气体为气态的过氧化氢，其在灭菌舱101灭菌过程中有部分过氧化氢气体分解成氧气和水蒸气，降低了过氧化氢的浓度，通过冷凝装置对过氧化氢和水蒸气的混合体进行一定程度的降温，能够使水蒸气冷凝成液态水与过氧化氢气体分离，从而对过氧化氢气体进行提纯，能够提高后续的灭菌效果。
步骤400：控制系统操控加热装置150对缓存舱110内的灭菌气体进行加热，温度检测装置检测灭菌气体的实时温度，通过加热装置150和温度检测装置155配合对过氧化氢气体进行加热并保持在恒温状态，避免过氧化氢气体持续冷却由气态变为液态积存在缓存舱110底部，导致进入到灭菌舱101内的灭菌气体减少，影响灭菌效果。在本实施方式中，加热装置150对过氧化氢加热的温度保持在70℃-75℃为最佳温度状态。
步骤500：浓度检测装置111检测缓存舱110内的灭菌气体的浓度并传输给控制系统与预设阈值比较。此处的阈值需要根据缓存舱110的体积、灭菌气体在灭菌舱101内灭菌的时间和灭菌气体分解速率等因素决定的，且阈值为多个，灭菌气体每进入到缓存舱110内一次均对应一个阈值，进入次数越多，阈值越小。通过灭菌气体在灭菌舱101内灭菌的时间和灭菌气体分解速率计算出已消耗的灭菌气体体积，进一步计算出剩余灭菌气体的体积，再通过剩余灭菌气体的体积和缓存舱110的体积计算出第一次灭菌气体进入到缓存舱110内的浓度，即第一个阈值。再根据上述计算过程计算出多个阈值，假设灭菌气体进入到缓存舱110所间隔的时间是一定的，则阈值与进入次数大致成反比关系。
如缓存舱110内的灭菌气体浓度大于或等于阈值，则控制系统操控第二控制阀133打开并启动第二空气泵135，缓存舱110内的灭菌气体完全进入到灭菌舱101内，然后关闭第二控制阀133和第二空气泵135，灭菌气体附着在医疗器械表面并进入到管腔类器械内部进行灭菌。
如缓存舱110内的灭菌气体浓度小于阈值，则控制系统操控蒸发器向灭菌舱101内充入一定体积的灭菌气体后，再操控第二控制阀133打开，缓存舱110内的灭菌气体进入到灭菌舱101内，然后关闭第二控制阀133和第二空气泵135，通过蒸发器补充灭菌气体使灭菌舱101内的灭菌气体达到所需浓度。
步骤600：重复步骤100-步骤500，直至灭菌工作完成。
 工业实用性
由上文所述的实施方式可知，本申请具有工业实用性。
 序列表自由内容
以上所述仅是本发明的优选实施方式，应当理解本发明并非局限于本文所披露的形式，不应看作是对其他实施例的排除，而可用于各种其他组合、修改和环境，并能够在本文所述构想范围内，通过上述教导或相关领域的技术或知识进行改动。而本领域人员所进行的改动和变化不脱离本发明的精神和范围，则都应在本发明所附权利要求的保护范围内。

Claims (9)

  1. 一种高效率灭菌的过氧化氢等离子灭菌器，包括安装有真空泵、蒸发器、灭菌舱（101）和控制系统的灭菌器本体（100），其特征在于：还包括设有容纳腔的缓存舱（110），缓存舱（110）通过第一管道（113）和第二管道（130）与灭菌舱（101）连通；
    第一管道（113）上安装有第一空气泵（117）和第一控制阀（119），第二管道（130）上安装有第二控制阀（133），第一控制阀（119）用于打开或关闭第一管道（113），第二控制阀（133）用于打开或关闭第二管道（130）；
    第一空气泵（117）、第一控制阀（119）和第二控制阀（133）均与控制系统电连接。
  2. 根据权利要求1所述的一种高效率灭菌的过氧化氢等离子灭菌器，其特征在于：在缓存舱（110）上设置有浓度检测装置，浓度检测装置的一端贯穿缓存舱（110）的侧壁伸入到容纳腔内，且与缓存舱（110）的侧壁连接；
    在缓存舱（110）上设置有加热装置（150）和温度检测装置（155），加热装置（150）用于对缓存舱（110）进行加热，温度检测装置（155）用于检测容纳腔内的温度值；
    浓度检测装置、温度检测装置（155）和加热装置（150）均与控制系统电连接。
  3. 根据权利要求1所述的一种高效率灭菌的过氧化氢等离子灭菌器，其特征在于：加热装置（150）安装在缓存舱（110）的侧壁上，加热装置（150）包括外壳（151）和安装在外壳（151）内的加热件（153），外壳（151）上开设有通风口（157）。
  4. 根据权利要求1所述的一种高效率灭菌的过氧化氢等离子灭菌器，其特征在于：在缓存舱（110）上还设置有压力检测装置（159），压力检测装置（159）与控制系统连接，压力检测装置（159）用于检测容纳腔内的压力值。
  5. 根据权利要求1所述的一种高效率灭菌的过氧化氢等离子灭菌器，其特征在于：缓存舱（110）上设置有冷凝装置（170）和储存罐（171），冷凝装置（170）安装在缓存舱（110）的侧壁上，用于对灭菌气体进行降温；储存罐（171）安装在缓存舱（110）的底面且与容纳腔连通，储存罐（171）与缓存舱（110）螺纹连接，储存罐（171）用于放置干燥剂。
  6. 根据权利要求5所述的一种高效率灭菌的过氧化氢等离子灭菌器，其特征在于：冷凝装置（170）包括至少一个风扇（173）和至少一个导热件（175），风扇（173）通过导热件（175）安装在缓存舱（110）的侧壁上。
  7. 根据权利要求1所述的一种高效率灭菌的过氧化氢等离子灭菌器，其特征在于：第二管道（130）上还安装有第二空气泵（135），第二空气泵（135）与控制系统电连接。
  8. 一种过氧化氢等离子灭菌器的灭菌方法，其特征在于，基于权利要求1~7任意一项所述过氧化氢等离子灭菌器进行灭菌，包括以下步骤：
    步骤100：将医疗器械放入灭菌舱（101）内，关闭灭菌舱（101）后，打开第二控制阀（133）并启动灭菌器，通过真空泵对灭菌舱（101）和缓存舱（110）进行抽真空工作；然后关闭第二控制阀（133），将灭菌气体送入灭菌舱（101）进行灭菌；
    步骤200：灭菌气体进入到灭菌舱（101）一段时间后，通过控制系统打开第一空气泵（117）和第一控制阀（119），将灭菌舱（101）内的灭菌气体送入缓存舱（110）内，灭菌舱（101）内为真空状态时，关闭第一控制阀（119）和第一空气泵（117）；
    步骤300：冷凝装置（170）启动对缓存舱（110）内的灭菌气体进行降温，灭菌气体中的水蒸气冷凝成液态水；
    步骤400：控制系统操控加热装置（150）对缓存舱（110）内的灭菌气体进行加热，温度检测装置（155）检测灭菌气体的实时温度；
    步骤500：浓度检测装置（111）检测缓存舱（110）内的灭菌气体的浓度并传输给控制系统与预设阈值比较，如缓存舱（110）内的灭菌气体浓度大于或等于阈值，则控制系统操控第二控制阀（133）打开并启动第二空气泵（135），缓存舱（110）内的灭菌气体进入到灭菌舱（101）内，然后关闭第二控制阀（133）和第二空气泵（135）；
    如缓存舱（110）内的灭菌气体浓度小于阈值，则控制系统操控蒸发器向灭菌舱（101）内充入一定体积的灭菌气体后，再操控第二控制阀（133）打开，缓存舱（110）内的灭菌气体进入到灭菌舱（101）内，然后关闭第二控制阀（133）和第二空气泵（135）；
    步骤600：重复步骤100-步骤500，直至灭菌工作完成。
  9. 根据权利要求8所述的一种过氧化氢等离子灭菌器的灭菌方法，其特征在于：步骤400中，加热装置（150）加热达到的温度值为70℃-75℃。
PCT/CN2022/091417 2021-12-30 2022-05-07 一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法 WO2023123799A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202111649950.3A CN114306692A (zh) 2021-12-30 2021-12-30 一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法
CN202111649950.3 2021-12-30

Publications (1)

Publication Number Publication Date
WO2023123799A1 true WO2023123799A1 (zh) 2023-07-06

Family

ID=81018161

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2022/091417 WO2023123799A1 (zh) 2021-12-30 2022-05-07 一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法

Country Status (2)

Country Link
CN (1) CN114306692A (zh)
WO (1) WO2023123799A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114306692A (zh) * 2021-12-30 2022-04-12 老肯医疗科技股份有限公司 一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法

Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1153668A (zh) * 1995-10-27 1997-07-09 庄臣及庄臣医药有限公司 使用无机过氧化氢配合物蒸汽消毒
CN1195996A (zh) * 1995-07-27 1998-10-14 美国消毒器公司 过氧化氢蒸气去污的实时监测器及控制系统和方法
CN101618226A (zh) * 2009-08-12 2010-01-06 成都老肯科技有限公司 过氧化氢等离子体灭菌器及其灭菌方法
CN101721724A (zh) * 2010-01-08 2010-06-09 邵汉良 过氧化氢等离子体增强灭菌器
EP2506884A1 (en) * 2009-12-03 2012-10-10 Minntech Corporation Container and system for decontaminating a medical device with a fog
US20130004384A1 (en) * 2010-03-17 2013-01-03 Chul Won Yoo Sterilizing apparatus and method using hydrogen peroxide
CN203001498U (zh) * 2012-12-29 2013-06-19 成都老肯科技股份有限公司 一种适用于过氧化氢等离子体灭菌器的提纯装置
CN103585650A (zh) * 2013-07-09 2014-02-19 西安交通大学 一种低温等离子体内窥镜消毒装置及方法
US20170252474A1 (en) * 2016-03-02 2017-09-07 Ethicon, Inc. Method of sterilizing medical devices, analyzing biological indicators, and linking medical device sterilization equipment
CN107551296A (zh) * 2016-06-30 2018-01-09 伊西康公司 用于对内窥镜进行灭菌的设备和方法
CN109289067A (zh) * 2018-11-16 2019-02-01 成都凌英科技有限公司 一种器械灭菌器、器械灭菌系统及器械灭菌方法
CN208974716U (zh) * 2018-07-24 2019-06-14 上海汉尼生物技术有限公司 一种过氧化氢低温循环灭菌装置
CN113134104A (zh) * 2021-05-12 2021-07-20 浙江迈尔医疗技术有限公司 一种过氧化氢低温灭菌器、灭菌方法及提纯装置
CN113577337A (zh) * 2014-12-22 2021-11-02 蓝波技术公司 等离子体处理装置及物品处理方法
CN114306692A (zh) * 2021-12-30 2022-04-12 老肯医疗科技股份有限公司 一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000097906A (ja) * 1998-09-21 2000-04-07 Shibuya Kogyo Co Ltd 滅菌装置における滅菌ガス濃度制御装置
US20040262146A1 (en) * 2000-10-02 2004-12-30 Platt Robert C. Sterilization system plasma generation control
CN203329080U (zh) * 2013-06-26 2013-12-11 苏州工业园区鸿基洁净科技有限公司 微生物消毒装置
KR101524042B1 (ko) * 2013-07-15 2015-06-01 (주) 씨엠테크 멸균장치 및 이를 이용한 멸균방법
CN103405797B (zh) * 2013-08-13 2016-03-16 老肯医疗科技股份有限公司 适用于内镜灭菌的过氧化氢低温灭菌设备及其使用方法
CN103520748B (zh) * 2013-10-18 2015-11-18 淄博康元医疗器械有限公司 三氧低温灭菌器的多级抽真空装置及方法
KR101732677B1 (ko) * 2015-10-13 2017-05-04 주식회사 큐브인스트루먼트 부피 가변식 챔버를 가지는 저온 멸균장치
CN109125768A (zh) * 2018-10-26 2019-01-04 湖北科益药业股份有限公司 药用铝管灭菌的真空脉动过氧化氢灭菌装置
CN212575308U (zh) * 2020-03-07 2021-02-23 老肯医疗科技股份有限公司 一种能产生循环气流的灭菌装置

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1195996A (zh) * 1995-07-27 1998-10-14 美国消毒器公司 过氧化氢蒸气去污的实时监测器及控制系统和方法
CN1153668A (zh) * 1995-10-27 1997-07-09 庄臣及庄臣医药有限公司 使用无机过氧化氢配合物蒸汽消毒
CN101618226A (zh) * 2009-08-12 2010-01-06 成都老肯科技有限公司 过氧化氢等离子体灭菌器及其灭菌方法
EP2506884A1 (en) * 2009-12-03 2012-10-10 Minntech Corporation Container and system for decontaminating a medical device with a fog
EP2586465A1 (en) * 2009-12-03 2013-05-01 Minntech Corporation System for decontaminating a medical device with a fog
CN101721724A (zh) * 2010-01-08 2010-06-09 邵汉良 过氧化氢等离子体增强灭菌器
US20130004384A1 (en) * 2010-03-17 2013-01-03 Chul Won Yoo Sterilizing apparatus and method using hydrogen peroxide
CN203001498U (zh) * 2012-12-29 2013-06-19 成都老肯科技股份有限公司 一种适用于过氧化氢等离子体灭菌器的提纯装置
CN103585650A (zh) * 2013-07-09 2014-02-19 西安交通大学 一种低温等离子体内窥镜消毒装置及方法
CN113577337A (zh) * 2014-12-22 2021-11-02 蓝波技术公司 等离子体处理装置及物品处理方法
US20170252474A1 (en) * 2016-03-02 2017-09-07 Ethicon, Inc. Method of sterilizing medical devices, analyzing biological indicators, and linking medical device sterilization equipment
CN107551296A (zh) * 2016-06-30 2018-01-09 伊西康公司 用于对内窥镜进行灭菌的设备和方法
CN208974716U (zh) * 2018-07-24 2019-06-14 上海汉尼生物技术有限公司 一种过氧化氢低温循环灭菌装置
CN109289067A (zh) * 2018-11-16 2019-02-01 成都凌英科技有限公司 一种器械灭菌器、器械灭菌系统及器械灭菌方法
CN113134104A (zh) * 2021-05-12 2021-07-20 浙江迈尔医疗技术有限公司 一种过氧化氢低温灭菌器、灭菌方法及提纯装置
CN114306692A (zh) * 2021-12-30 2022-04-12 老肯医疗科技股份有限公司 一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法

Also Published As

Publication number Publication date
CN114306692A (zh) 2022-04-12

Similar Documents

Publication Publication Date Title
JP6530458B2 (ja) 滅菌装置
KR100966933B1 (ko) 오존소독방법 및 오존소독장치
ES2273518T3 (es) Procedimiento de concentracion de un esterilizante de articulos con el mismo.
JP5480975B2 (ja) 滅菌方法及び装置
US9827341B2 (en) Method for sterilising and sterilising device
JP2003521999A (ja) 内視鏡の殺菌方法
BRPI0715988A2 (pt) mÉtodo para a esterilizaÇço de um artigo em uma atmosfera de gÁs de esterilizaÇço
KR101758077B1 (ko) 멸균장치 및 이를 이용한 멸균방법
KR20060066056A (ko) 개량된 오존 살균 방법
TW200722114A (en) Method and apparatus for low energy vaporization of liquid oxidizing agents or solutions
JP4270758B2 (ja) オゾン消毒のための方法並びに装置
WO2023123799A1 (zh) 一种高效率灭菌的过氧化氢等离子灭菌器及灭菌方法
CA2993701A1 (en) Apparatus and method for detecting moisture in a vacuum chamber
JP2017507737A (ja) 滅菌装置の真空排気システム
EP2139527A1 (en) Quantitative liquid injection device of plasma sterilizer
CN113134104B (zh) 一种过氧化氢低温灭菌器、灭菌方法及提纯装置
CN103083699B (zh) 一种适用于过氧化氢等离子体灭菌器的提纯装置
CN111467539B (zh) 一种适用于医用口罩消毒的过氧化氢气体消毒系统及方法
US20200375691A1 (en) Peracetic acid vapor sterilization system
CN114904021B (zh) 一种脉动真空压力蒸汽灭菌器及灭菌方法
CN106693016A (zh) 一种气体灭菌装置及方法
CN203001498U (zh) 一种适用于过氧化氢等离子体灭菌器的提纯装置
JP2008104488A (ja) オゾン滅菌方法
CN214435548U (zh) 一种过氧化氢灭菌装置
KR20100123229A (ko) 가습기의 멸균 기능을 갖는 멸균장치

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 22913095

Country of ref document: EP

Kind code of ref document: A1