WO2021147092A1 - Composition de graisse, graisse pour aliment, procédé de préparation et utilisation associés - Google Patents

Composition de graisse, graisse pour aliment, procédé de préparation et utilisation associés Download PDF

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Publication number
WO2021147092A1
WO2021147092A1 PCT/CN2020/074009 CN2020074009W WO2021147092A1 WO 2021147092 A1 WO2021147092 A1 WO 2021147092A1 CN 2020074009 W CN2020074009 W CN 2020074009W WO 2021147092 A1 WO2021147092 A1 WO 2021147092A1
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Prior art keywords
oil
bile acid
fat
salt
bile
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PCT/CN2020/074009
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English (en)
Chinese (zh)
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赖州文
龙吉云
章亮
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徐州新奥生物科技有限公司
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Priority to PCT/CN2020/074009 priority Critical patent/WO2021147092A1/fr
Publication of WO2021147092A1 publication Critical patent/WO2021147092A1/fr

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/20—Animal feeding-stuffs from material of animal origin
    • A23K10/26—Animal feeding-stuffs from material of animal origin from waste material, e.g. feathers, bones or skin
    • A23K10/28—Animal feeding-stuffs from material of animal origin from waste material, e.g. feathers, bones or skin from waste dairy products
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81—Aquaculture, e.g. of fish
    • Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87—Re-use of by-products of food processing for fodder production

Definitions

  • the present application generally relates to the field of animal feed products; more specifically, the present application relates to fat compositions suitable for animal feeding, feed fats, and preparation methods and applications thereof.
  • Feed fats can provide energy and essential fatty acids for animals. Animals lacking essential fatty acids may cause undesirable results such as growth arrest, decreased reproductive function, subcutaneous edema and bleeding, and body color dullness. Feed oil is also used as a carrier for fat-soluble vitamins A, D, carotenoids, etc., to promote the absorption and utilization of vitamins as fat-soluble substances.
  • the omega 3 fatty acids in feed oil can reduce prostaglandins, thereby increasing the level of antibody production in the carcass, saving the amount of antibiotics for livestock, and achieving the effect of disease prevention and treatment.
  • Emulsifiers are added to the current production process of feed fats to create a hydrophilic environment for the fats to improve the digestion, absorption and utilization rate of the fats.
  • Bile acids are now used as additives in the production of animal feed. Studies have found that bile acids can emulsify fat in the animal body and expand its contact area with lipase; regulate the activities of pancreatic lipase and lipoprotein esterase to improve the hydrolysis and metabolism of fat; bile acids transport fat in the intestine , Promote the absorption of fat. In addition, bile acids can significantly reduce the catabolism of autologous fat by regulating the activity of hormone-sensitive lipase. Bile acids can save energy raw materials, increase energy utilization, improve growth performance and slaughter performance, and are the "positive energy" for saving resources.
  • the present application provides a fat composition
  • a fat composition comprising bile acid, bile acid derivative, bile acid salt or a mixture thereof, and fat, wherein the fat is modified by the bile acid, bile acid derivative, bile acid salt Or its mixture is milky and micronized.
  • the bile acid derivative is selected from the group consisting of deoxybile acid, chenodeoxy bile acid, ursodeoxy bile acid, hyodeoxy bile acid, and any combination thereof.
  • the bile acid salt is selected from sodium salt, potassium salt, calcium salt, magnesium salt, and any combination thereof.
  • the oil is selected from fish oil, linseed oil, seaweed oil, palm oil, coconut oil, rice oil, soybean oil, medium chain triglycerides, and any combination thereof.
  • the oil is rich in omega-3 fatty acids.
  • the diameter of the formed milkweed microparticles is 10 ⁇ m or less.
  • the present application provides a method for preparing an oil composition, which comprises emulsifying and homogenizing bile acid, bile acid derivative, bile acid salt or mixture thereof with emulsifier, microcapsule packaging material and oil.
  • the method further includes spray drying the homogenized product.
  • the bile acid derivative is selected from deoxybile acid, chenodeoxybile acid, ursodeoxybile acid, hyodeoxybile acid, and any combination thereof.
  • the bile acid salt is selected from sodium salt, potassium salt, calcium salt, magnesium salt, and any combination thereof.
  • the emulsifier is selected from the group consisting of sodium stearoyl lactylate, sodium caseinate, mono/diglycerides (e.g., glyceryl mono/distearate), and any combination thereof.
  • the microcapsule packaging material is selected from modified starch, dextrin, syrup, chitosan, lactose, whey powder, and any combination thereof.
  • the oil is selected from fish oil, linseed oil, seaweed oil, palm oil, coconut oil, rice oil, soybean oil, medium chain triglycerides and any combination thereof.
  • the oil is rich in omega -3 fatty acids.
  • the bile acid, bile acid derivative, bile acid salt, or mixture thereof is 0.1 wt.% to 20 wt.%.
  • the fat is 5 wt.% to 80 wt.%.
  • the emulsifier is 0.4 wt.% to 13 wt.%.
  • the microcapsule packaging material is 0.1 wt.% to 90 wt.%.
  • the method includes the following steps:
  • Dissolve bile acid, bile acid derivatives, bile acid salts or mixtures thereof in a weakly alkaline aqueous solution for example, use alkaline sodium salt or sodium hydroxide to adjust the pH to 8-12
  • a weakly alkaline aqueous solution for example, use alkaline sodium salt or sodium hydroxide to adjust the pH to 8-12
  • the materials are mixed and dissolved separately or mixed and dissolved in water, and the above aqueous solutions are mixed again to obtain the water phase;
  • spray drying is performed on the homogenized product.
  • the grease composition prepared according to the method described in the second aspect has the properties of the grease composition described in the first aspect.
  • the present application provides feed fats and oils, which comprise the fat composition of the first aspect or the fat composition prepared according to the method of the second aspect.
  • this application provides the oil composition of the first aspect, or the oil composition prepared according to the method of the second aspect, or the use of the feed fat of the third aspect in animal feeding.
  • Figures 1 to 4 show a transmission electron microscope comparison of a bile acid-free grease composition prepared according to conventional techniques (above picture) and a grease composition according to the method of the present application (below picture), wherein the magnifications of Figs. 1 to 4 Respectively 2500, 10000, 25000, 50000 times.
  • Bile acids can emulsify fat in the animal body to form chylous microparticles. If chylous microparticles can be achieved in the production process of feed fats (in vitro), the intestinal mucosal epithelial cells can better recognize them. Grease quickly transports and transfers oil into the body with affinity. As an exogenous bioemulsifier, bile acid can activate lipase and improve the digestion, absorption and utilization rate of fat, in addition to transporting fat as particles.
  • bile acid derivative refers to a substance suitable for administration to animals whose structure is derived from bile acid.
  • common bile acid derivatives are deoxy bile acids, such as chenodeoxy bile acid, ursodeoxy bile acid, hyursodeoxy bile acid, and the like.
  • bile salt refers to a salt of bile acid suitable for administration to animals.
  • suitable bile acid salts include sodium, potassium, calcium, magnesium, and the like.
  • fat refers to oils and fats suitable as animal feed.
  • suitable oils include, but are not limited to, fish oil, linseed oil, seaweed oil, palm oil, coconut oil, rice oil, soybean oil, medium chain triglycerides, and the like.
  • emulsifier used herein is in accordance with the meaning understood by those skilled in the field of feed fat production.
  • suitable emulsifiers include, but are not limited to, sodium stearoyl lactylate, sodium caseinate, mono/diglycerides (such as glyceryl mono/distearate) and the like.
  • microcapsule packaging material also called “microcapsule wall material” has the meaning understood by those skilled in the field of feed fat production.
  • the microcapsule packaging material is a part of the water phase, and the water phase and the oil phase are homogenized by grinding or shearing, and then spray-dried to form microcapsules.
  • suitable microcapsule packaging materials include, but are not limited to, modified starch, dextrin, syrup, chitosan, lactose, whey powder and the like.
  • the present application provides a fat composition
  • a fat composition comprising bile acid, bile acid derivative, bile acid salt or a mixture thereof, and fat, wherein the fat is modified by the bile acid, bile acid derivative, bile acid salt Or its mixture is milky and micronized.
  • bile acid derivatives such as deoxybile acid, chenodeoxy bile acid, ursodeoxy bile acid, and any combination thereof.
  • the bile acid salt is selected from sodium salt, potassium salt, calcium salt, magnesium salt, and any combination thereof.
  • the oil is selected from fish oil, linseed oil, seaweed oil, palm oil, coconut oil, rice oil, soybean oil, medium chain triglycerides, and any combination thereof.
  • the oil is rich in omega-3 fatty acids.
  • the diameter of the formed milkweed microparticles is 10 ⁇ m or less.
  • the present application provides a method for preparing an oil composition, which comprises emulsifying and homogenizing bile acid, bile acid derivative, bile acid salt or mixture thereof with emulsifier, microcapsule packaging material and oil.
  • the method further includes spray drying the emulsified homogenized product.
  • bile acid derivatives such as deoxybile acid, chenodeoxy bile acid, ursodeoxy bile acid, and any combination thereof.
  • the bile acid salt is selected from sodium salt, potassium salt, calcium salt, magnesium salt, and any combination thereof.
  • the emulsifier is selected from the group consisting of sodium stearoyl lactylate, sodium caseinate, mono/diglycerides (e.g., glyceryl mono/distearate), and any combination thereof.
  • the microcapsule packaging material is selected from modified starch, dextrin, syrup, chitosan, lactose, whey powder, and any combination thereof.
  • the oil is selected from fish oil, linseed oil, seaweed oil, palm oil, coconut oil, rice oil, soybean oil, medium chain triglycerides and any combination thereof.
  • the oil is rich in omega -3 fatty acids.
  • the bile acid, bile acid derivative, bile acid salt, or mixture thereof is 0.1 wt.% to 20 wt.%, for example, 0.1 wt.%, 0.5 wt.% , 1wt.%, 2wt.%, 3wt.%, 4wt.%, 5wt.%, 6wt.%, 7wt.%, 8wt.%, 9wt.%, 10wt.%, 11wt.%, 12wt.%, 13wt %, 14wt.%, 15wt.%, 16wt.%, 17wt.%, 18wt.%, 19wt.%, 20wt.%, or a range composed of any two of the above values.
  • the bile acid, bile acid derivative, bile acid salt, or mixture thereof is 1 wt.% to 10 wt.%. In some embodiments, based on the total weight of the fat composition, the bile acid, bile acid derivative, bile acid salt, or mixture thereof is 1 wt.% to 5 wt.%.
  • the fat is 5wt.% to 80wt.%, for example, 5wt.%, 10wt.%, 15wt.%, 20wt.%, 25wt.%, 30wt.% , 35wt.%, 40wt.%, 45wt.%, 50wt.%, 55wt.%, 60wt.%, 65wt.%, 70wt.%, 75wt.%, 80wt.%, or a range of any two of the above values . In some embodiments, based on the total weight of the fat composition, the fat is 10 wt.% to 50 wt.%. In some embodiments, based on the total weight of the grease composition, the fat is 30 wt.% to 50 wt.%.
  • the emulsifier is 0.4wt.%-13wt.%, for example, 0.4wt.%, 0.6wt.%, 0.8wt.%, 1wt.%, 2wt. %, 3wt.%, 4wt.%, 5wt.%, 6wt.%, 7wt.%, 8wt.%, 9wt.%, 10wt.%, 11wt.%, 12wt.%, 13wt.%, or any two of the above A range of values.
  • the microcapsule packaging material is 0.1wt.% to 90wt.%, for example, 0.1wt.%, 0.5wt.%, 1wt.%, 5wt.%, 10wt. %, 15wt.%, 20wt.%, 25wt.%, 30wt.%, 35wt.%, 40wt.%, 45wt.%, 50wt.%, 55wt.%, 60wt.%, 65wt.%, 70wt.%, 75wt.%, 80wt.%, 85wt.%, 90wt.%, or a range composed of any two of the above values.
  • the method includes the following steps:
  • the grease in step (b) is heated to 50°C to 90°C, for example, 50°C, 55°C, 60°C, 65°C, 70°C, 75°C, 80°C, 85°C, 90°C .
  • the emulsification treatment is colloidal grinding or shear pump shearing.
  • the homogenization treatment is performed under high pressure, such as 20-45 MPa, for example, 20 MPa, 25 MPa, 30 MPa, 35 MPa, 40 MPa, 45 MPa.
  • spray drying is performed under high pressure, such as 2-20 MPa, such as 2 MPa, 5 MPa, 10 MPa, 15 MPa, 20 MPa.
  • the inlet air temperature of spray drying is controlled at 135-210°C (for example, 135°C, 140°C, 150°C, 160°C, 170°C, 180°C, 190°C, 200°C, 210°C).
  • the wind temperature is controlled to 55-105°C (for example, 55°C, 65°C, 75°C, 85°C, 95°C, 105°C).
  • the preparation method of the grease composition can be implemented as follows:
  • the water phase and the oil phase are mixed and ground by a colloid mill or sheared by a high-shear pump.
  • the homogenization pressure is controlled to 20-45MPa to homogenize the material liquid at high pressure, and the homogenized emulsion is filled into bile acid emulsified oil. If filling is not carried out, the material can be pressurized to 2-20MPa by a high-pressure pump for pressure spray drying. Control the inlet air temperature of the drying tower to 135-210°C and the outlet temperature of 55-105°C to spray dry the material to obtain water-soluble bile acid emulsified oil microcapsule powder.
  • the grease composition prepared according to the method described in the second aspect has the properties of the grease composition described in the first aspect.
  • the microencapsulated fat prepared according to the method of the present application because the wall material of the microcapsule usually contains sweet syrup or dextrin and other substances, through the process of the present application, the bile acid is bounded between the oil phase and the water phase syrup.
  • the sweetness of the material can conceal the bitterness of bile acid to a certain extent and help solve the problem of palatability.
  • the microencapsulated oil prepared according to the method of the present application can realize the milk micronization of the oil in vitro, which enables the intestinal mucosal epithelial cells to better recognize the oil and affinity to quickly transport and transport the oil into the body.
  • bile acid can activate lipase and improve the digestion, absorption and utilization rate of oil, in addition to transporting oil as particles.
  • the present application provides feed fats and oils, which comprise the fat composition of the first aspect or the fat composition prepared according to the method of the second aspect.
  • this application provides the oil composition of the first aspect, or the oil composition prepared according to the method of the second aspect, or the use of the feed fat of the third aspect in animal feeding.
  • Animals suitable for administering the fat composition or feed fat of the present application include but are not limited to livestock and poultry, fish and the like. Animals suitable for administering the feed composition of the present application are not particularly limited, and suitable animals may be, for example, livestock, poultry, or aquatic products.
  • the "livestock” in this article refers to mammals in the breeding industry, such as pigs, cattle, sheep, dogs, cats, rabbits, etc.
  • the "poultry” in this article refers to poultry animals in the breeding industry, such as chickens, ducks, geese, and bird breeding animals.
  • “Aquatic products” in this article refers to aquatic animals in the aquaculture industry, such as fish, shrimp, crabs, and bullfrogs.
  • the fat composition or feed fat of the present application can be directly added to water for animals to drink or directly mixed with feed and eaten.
  • the beneficial effects that can be achieved by using the oil composition of the present application for feeding animals include, but are not limited to, improving the laying quality of laying hens (for example, increasing the DHA content of eggs), and increasing the newborn weight, weaning weight, and daily weight gain of newborn mammals. Or weaning survival rate to promote fish growth.
  • the preparation process is as follows:
  • the water phase and the oil phase are mixed, and ground by a colloid mill or sheared by a high-shear pump, and the homogenization pressure is controlled to 20-45MPa to perform high-pressure homogenization of the material liquid, and the homogenized emulsion is filled into bile acid emulsified oil. If filling is not carried out, the material can be pressurized by a high-pressure pump to 2-20MPa for pressure spray drying. Control the inlet air temperature of the drying tower to 135-210°C and the outlet temperature of 55-105°C to spray dry the material to obtain water-soluble bile acid emulsified oil microcapsule powder.
  • the fat composition prepared in Example 1 was added to grass carp feed and broiler feed at a ratio of 3 kg/t, and fed to grass carp and broiler chickens for four weeks, respectively.
  • the serum triglycerides, intestinal compact protein, malondialdehyde, Liver glutathione peroxidase (GSH-PX) and superoxidase (SOD) are used as indicative indicators for detection.
  • feed simply mixed with bile acids for example, 2.91 kg of ordinary feed + 90 grams of bile acid
  • bile acids for example, 2.91 kg of ordinary feed + 90 grams of bile acid
  • Example 1 The oil and fat composition prepared in Example 1 was subjected to transmission film analysis with a control oil and fat composition prepared according to a conventional process similar to that in Example 1, but without bile acid components. As shown in Figures 1-4, in the oil composition prepared according to the method of the present application, the hydrophilic and lipophilic groups of bile acid are combined between water and oil. The emulsified and dispersed emulsified oil particles are further dispersed into smaller chylomicrons; while the control oil composition does not have such properties.
  • the raw material formulation of the grease composition tested in this example is shown in Table 2, and the preparation process refers to Example 1.
  • Bile acid salt 3% Deep sea fish oil 50% Glyceryl monostearate 2.5% Sodium stearoyl lactylate 1.5% Sodium Caseinate 3% Modified starch 5% dextrin 35%
  • Test site Zhiyu Farm, Yuanyang County, Xinxiang City, Henan province
  • Control group (conventional feed for laying hens)
  • Test group (conventional feed for laying hens + 5% oil composition of this embodiment)
  • adding the oil composition of the present application to the diet of laying hens can increase the DHA content of eggs.
  • Example 5 Testing of newborn weight, weaning weight and weaning survival rate of suckling piglets
  • Test site Xinfa Farm, Xihua County, Zhoukou City, Henan province
  • Control group (Regular feed for lactating sows)
  • Test group (Regular feed for lactating sows + 2% oil composition of this embodiment)
  • adding the lipid composition of the present application to the diet of perinatal and lactating sows can increase the newborn weight of suckling piglets, the average weaning rate of suckling piglets, and the survival rate of suckling piglets from weaning.
  • Example 6 Testing of newborn weight, weaning weight and weaning survival rate of suckling piglets
  • the raw material composition of the grease composition tested in this example is shown in Table 6, and the preparation process refers to Example 1.
  • Control group (Regular feed for lactating sows)
  • Test group (Regular feed for lactating sows + 2% of the oil composition of the present embodiment)
  • adding the oil composition of the present application to the diets of perinatal and lactating sows can increase the average weaning weight of suckling piglets, the daily increase of suckling piglets, and the survival rate of suckling piglets from weaning.
  • the raw material composition of the grease composition tested in this example is shown in Table 8, and the preparation process refers to Example 1.
  • Test 1 group (self-prepared sea bass diet + 0.5% compound 1)
  • Test 2 group (self-prepared seabass diet + 0.5% compound 2)
  • Test 3 groups (self-prepared seabass diet + 0.5% oil composition of this embodiment)
  • Compound 2 is a mixture that has exactly the same components as the oil and fat composition of this example but has not been homogenized and emulsified.
  • Complex 1 is complex 2 without bile salts.
  • Each group has 4 repetitions, each repetition is one tank, and each tank has 20 seabass. Feed 3 times a day at regular intervals, and the experimental period is 8 weeks. The results are shown in Table 9 below:
  • AST Aspartate aminotransferase
  • ALT alanine aminotransferase
  • Alkaline phosphatase increased significantly, indicating that it is beneficial to improve the utilization of nutrients
  • the lipoprotein lipase (LPL) is significantly increased, and the triglyceride (TG) content in the liver is significantly reduced, indicating that the oil composition of the present application can increase the activity of lipolytic enzymes and reduce the liver triglyceride content.

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  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Birds (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
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  • Physiology (AREA)
  • Fodder In General (AREA)

Abstract

L'invention concerne une composition de graisse, comprenant de l'acide biliaire, un dérivé d'acide biliaire, un sel d'acide biliaire ou un mélange de ceux-ci, et de la graisse. La graisse est granulée par l'acide biliaire, le dérivé d'acide biliaire et le sel d'acide biliaire, ou un mélange de ceux-ci. L'invention concerne également un procédé de préparation de ladite composition de graisse, une graisse pour aliment comprenant une composition de graisse et une utilisation d'une composition de graisse ou d'une graisse pour aliment dans l'élevage d'animaux.
PCT/CN2020/074009 2020-01-23 2020-01-23 Composition de graisse, graisse pour aliment, procédé de préparation et utilisation associés WO2021147092A1 (fr)

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Citations (9)

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WO2010072584A1 (fr) * 2008-12-23 2010-07-01 Dsm Ip Assets B.V. Acides biliaires dans des aliments pour réduire la production de méthane émanant des activités digestives des ruminants
US20120004304A1 (en) * 2009-03-26 2012-01-05 Kimin Inc. Bile salt adjuvant for animals for improving fat utilization efficiency in the bodies of animals, and animal feed comprising same
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