WO2020093585A1 - 一种生物样本储存库及其储存方法 - Google Patents

一种生物样本储存库及其储存方法 Download PDF

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Publication number
WO2020093585A1
WO2020093585A1 PCT/CN2019/070359 CN2019070359W WO2020093585A1 WO 2020093585 A1 WO2020093585 A1 WO 2020093585A1 CN 2019070359 W CN2019070359 W CN 2019070359W WO 2020093585 A1 WO2020093585 A1 WO 2020093585A1
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WO
WIPO (PCT)
Prior art keywords
storage
lifting
tank
shoveling
basket
Prior art date
Application number
PCT/CN2019/070359
Other languages
English (en)
French (fr)
Inventor
瞿建国
罗沉
刘玲玲
王建信
Original Assignee
上海原能细胞生物低温设备有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 上海原能细胞生物低温设备有限公司 filed Critical 上海原能细胞生物低温设备有限公司
Priority to JP2021600063U priority Critical patent/JP3235995U/ja
Publication of WO2020093585A1 publication Critical patent/WO2020093585A1/zh

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G1/00—Storing articles, individually or in orderly arrangement, in warehouses or magazines
    • B65G1/02—Storage devices
    • B65G1/04—Storage devices mechanical

Definitions

  • the invention relates to the field of biological sample storage equipment, in particular to a biological sample storage library and a storage method thereof.
  • the biological sample library is a device for standardized collection, processing, and storage of samples of biological macromolecules, cells, tissues, and organs of healthy and disease organisms. Before storing biological samples, they need to be cooled down through a procedure to make them dormant, and then stored in a liquid nitrogen container or deep-freezer. For some specific biological samples, the storage process needs to ensure full cold chain protection, and the whole process needs to be in a deep low temperature environment to protect its biological activity and avoid repeated freeze-thaw damage.
  • cryopreservation tubes in the prior art is manually operated, which has many limitations: 1. During the storage process, the cryopreservation tubes or transfer tanks have been kept in a non-low temperature environment during the storage process.
  • the sample brings a great destructive risk; 2, manual storage enters the warehouse, you need to find the classification of the deep and low temperature storage tank of the biological sample, and then store it in it, which has low efficiency, high labor cost, and is not easy to store by classification , The risk is large; 3.
  • the size of the opening of the cryogenic storage tank must match the size of human operation, and the effect of opening the cryogenic storage tank on its own temperature during this process
  • Destructive take the deep and low temperature storage tank as a liquid nitrogen tank as an example, so the operation will consume a lot of nitrogen; 4.
  • Manual storage is easy to produce the influence of mutual movement between samples and mutual pollution, and the risk is high; 5.
  • Existing warehouse type The setting method is inconvenient to install, transport, and has poor adaptability on site; 6.
  • the subsequent maintenance of the deep and low temperature storage warehouse is very inconvenient.
  • This method can not guarantee the full cold chain protection of the cryopreservation tube during storage or retrieval; it not only has a great risk of damage to the biological samples in the cryopreservation tube, but also protects the full cold chain for some specific biological samples When the demand is high, this storage method of the prior art seems undesirable;
  • cryogenic storage tank itself has a large volume, and it is also very inconvenient when setting and transporting the cryogenic storage tank;
  • the prior art storage method is not good, the access tube is more inconvenient, which brings inconvenience to users.
  • An object of the present invention is to provide a biological sample storage, which solves the problem that the biological sample storage in the prior art cannot guarantee full cold chain protection, increases the risk of damage to the storage of biological samples, and solves the problems in the prior art.
  • the transportation of deep and low temperature storage tanks is very inconvenient.
  • Another object of the present invention is to provide a storage method for a biological sample storage library, which solves the problems in the prior art that the storage method is inconvenient, cannot guarantee the entire cold chain protection, and has low storage efficiency and inconvenient transportation.
  • a biological sample storage including a storage box, a plurality of cryogenic storage tanks and an automatic transfer mechanism; the at least one cryogenic storage tank and the automatic transfer mechanism are both It is installed in the storage box; the storage box is provided with a transfer window, and the automatic transfer mechanism can receive a transfer tank with a frozen storage tube transferred from the outside through the transfer window; and the automatic transfer The mechanism may transfer the frozen storage tube in the received transfer tank to the cryogenic storage tank.
  • a movable basket is provided in the deep-temperature storage tank, and a plurality of tray supports are provided in the basket, and the tray support supports a tray of freezing tubes; the deep-temperature storage tank A storage door is provided, and each of the tray supports can move with the basket to move to a position corresponding to the storage door; the automatic transfer mechanism includes a shoveling assembly that can be worn through The storage tube tray can be scooped up to receive the cryotube tray in the basket or the received cryotube tray can be shoveled back into the basket.
  • the shoveling component includes a shoveling box body, a shoveling first driving member, a shoveling second driving member, a shoveling sliding base, a sliding guide plate, a shovel disk assembly, and a temporary storage rack;
  • the shoveling box The body is provided with a shoveling and conveying opening, and the shoveling and conveying opening can correspond to the storage door of the deep and low temperature storage tank;
  • the temporary storage rack and the shoveling and sliding base are both provided in the shoveling and conveying box
  • the sliding guide plate is slidably provided on the shoveling sliding base, and the shovel plate assembly is slidably provided on the sliding guide plate;
  • the temporary storage rack can temporarily store the transfer tank;
  • the scooping box body is provided with a scooping nitrogen hole, the scooping nitrogen hole communicates with a nitrogen supply system;
  • the scooping first driving member drives the sliding guide plate to slide, and the scooping The second driving member is sent to drive the sliding of the shovel plate assembly.
  • the shoveling sliding base includes a left sliding seat, a right sliding seat and a base frame, and the left sliding seat and the right sliding seat are respectively provided on the left and right sides of the base frame;
  • the sliding guide plate includes a left sliding guide rail, a right sliding guide rail and a sliding plate; the left sliding guide rail and the right sliding guide rail are respectively provided on the left and right ends of the sliding plate;
  • the shovel plate assembly includes a shovel plate left slide, a shovel plate right slide and a shovel plate;
  • the left sliding seat includes a sliding support plate and a plurality of pulleys, and the plurality of pulleys are arranged in a row on the sliding support plate; the right sliding seat and the left sliding seat have the same structure and are symmetrically arranged;
  • the left sliding guide rail is in the shape of "I", and the right sliding guide rail has the same structure as the left sliding guide rail and is symmetrically arranged;
  • the first shoveling drive includes a shoveling drive motor and a screw, a screw nut is provided on the lower end surface of the sliding plate, the screw nut is screwed to the screw, and the motor shaft of the shoveling drive motor Connect with the lead screw.
  • the automatic transfer mechanism further includes a code scanning member, and the code scanning member can scan the frozen storage tube to be transferred.
  • the automatic transfer mechanism further includes a transfer receiving box and a manipulator;
  • the transfer receiving box and the scooping box are arranged side by side, and the manipulator is arranged above the scooping assembly and the transfer receiving box;
  • the transfer receiving box receives the transfer tank transported from the transfer window; the manipulator can grab the transfer tank;
  • a shoveling receiving port is opened on the upper end surface of the shoveling box body, and the manipulator can be moved to a position corresponding to the shoveling receiving port.
  • the automatic transfer mechanism further includes a transfer housing;
  • the manipulator includes a gripping drive assembly, a Z-axis sleeve, a Z-axis rod, a Y-axis guide rail, a first X-axis guide rail, a second X-axis guide rail, a gripping mechanism and Pipe fittings;
  • the first X-axis guide rail and the second X-axis guide rail are distributed and fixed on both side ends of the transfer housing, and the first X-axis guide rail and the second X-side guide rail are slidably provided on both side ends of the Y-axis guide rail On the shaft guide; the Z shaft sleeve is arranged vertically, and the middle of the Z shaft sleeve is slidably arranged on the Y axis guide rail;
  • the Z-axis rod is slidably disposed in the Z-axis sleeve, a Z-bearing connector is provided at a lower end of the Z-axis rod, and the can gripping mechanism and the pipe-taking member are respectively provided on the Z-bearing connector;
  • the tank grasping mechanism can grab the transfer tank, and the pipe-collecting member can take the frozen storage tube;
  • the grab drive assembly drives the movement of the Z-axis sleeve, Y-axis guide rail, and Z-axis rod, respectively.
  • the deep and low temperature storage tank is provided with a rotating frame, a rotating driving assembly and a lifting member;
  • the lifting member is nested in the rotating frame, and the upper part of the lifting member is fixed with the tank body of the cryogenic storage tank; the rotating driving assembly drives the rotating frame to make the rotating frame deep Rotating around the lifting member in the low-temperature storage tank;
  • the rotating frame is divided into a plurality of storage areas by a plurality of dividing plates, and the storage areas are all provided with lifting operation channels, and each of the lifting operation channels communicates with the lifting member;
  • a lifting basket is provided in the storage area; a pushing receiving block is extended outward from the periphery of the lifting basket, and the pushing receiving block extends through the lifting operation channel to a position corresponding to the lifting member;
  • the lifting member can drive the lifting basket to move up and down in the storage area along the lifting operation channel by acting on the pushing receiving block.
  • a transitional axial groove is recessed downward in the upper middle part of the rotating frame, and a plurality of partition plates extend outward from the periphery of the transitional axial groove, and the circumferential groove wall of the transitional axial groove
  • the upper opening is provided with a plurality of lifting operation channels; the lifting operation channels correspond one-to-one with the storage areas divided by the partition plates;
  • the lifting member includes a lifting sleeve, a lifting drive motor, a lifting driving wheel, a lifting driven wheel, a lifting transition wheel and a lifting platform;
  • the lifting sleeve is disposed in the transitional axial groove and can rotate relative to the rotating frame; the upper circumference of the lifting sleeve extends outwardly with a lifting transition plate, and the lifting drive motor is disposed at the deep low temperature The outside of the storage tank, and the motor of the lifting drive motor extends axially downward through the tank cover of the deep and low temperature storage tank and the lifting transition plate are provided with lifting driving wheels;
  • a lifting transition wheel and a lifting driving wheel are meshed and connected at the upper end of the lifting sleeve, a lifting driven wheel is provided at the lower end of the lifting sleeve, and a lifting wheel is provided between the lifting driven wheel and the lifting transition wheel Conveyor belt; a lifting platform is provided on the lifting transmission belt, and the lifting platform corresponds to the pushing receiving block.
  • a storage guide sliding track is provided on the partition plate, and a basket slide bar which is matched with the storage guide sliding track is provided on the periphery of the basket, and the basket slide bar is on the storage guide sliding track slide.
  • the lifting sleeve is a hollow tube sleeve
  • the center of the groove bottom of the transitional axial groove extends to the inside of the lifting sleeve with a rotation action shaft, and the upper end of the rotation action shaft is provided with a "ten" receiving groove;
  • the rotary drive assembly includes a rotary drive motor and a rotary drive shaft, the rotary drive motor is fixed outside the cryogenic storage tank, and the motor shaft of the rotary drive motor is coaxially connected to the rotary drive shaft, the The lower end of the rotary drive shaft is provided with a "ten" snap fitting, and the snap fitting of the rotary drive shaft is engaged in the receiving slot.
  • the basket is fan-shaped, and a plurality of support bars are provided on both sides of the basket, and each two support bars on the same horizontal plane form the tray support.
  • the frozen storage tube tray has a fan shape matching the carrying basket, and the frozen storage tube tray is provided with a plurality of storage tube grooves, and the bottom of the storage tube groove is a developed type groove bottom.
  • the inspection door is provided on the storage cabinet, and the storage cabinet can be opened through the inspection door to inspect the interior;
  • the nitrogen supply system can supply nitrogen to the storage box, and can also supply nitrogen to the automatic transfer mechanism;
  • the dehumidification system can dehumidify the storage box.
  • the present invention solves another technical problem by adopting the following technical solution: a storage method of a biological sample storage library, Step R, put the transfer tank with the frozen storage tube directly into the storage through the transfer window of the storage box; Step S, the automatic transfer mechanism in the storage will automatically transfer the frozen storage tube in the received transfer tank Transfer to the cryogenic storage tank.
  • step S1 the robot of the automatic transfer mechanism grabs the transfer tank received by the storage warehouse to the set temporary storage rack;
  • Step S2 while performing step S1 or after step R above, the automatic transfer mechanism will move along the designated line to the corresponding cryogenic storage tank;
  • Step S3 the storage door of the cryogenic storage tank is opened, and the shoveling assembly of the automatic transfer mechanism shovels the tray of the cryotube in the cryogenic storage tank onto the platform corresponding to the automatic transfer mechanism;
  • Step S4 the manipulator grabs the frozen storage tube in the transfer tank on the temporary storage rack and places it on the frozen storage tube tray;
  • step S5 the shoveling component transports the cryotube drag tray back to the deep and low temperature storage tank.
  • the manipulator first grabs the cryopreservation tube from the temporary storage rack and scans the two-dimensional code on the cryopreservation tube above the code scanning member, and sets the control system to scan the code The results are processed and stored, and then the cryotubes are grabbed onto the cryotube tray.
  • step T before the step S3 is performed, the corresponding basket in the cryogenic storage tank moves to a position corresponding to the storage door;
  • the T step is divided into:
  • step T1 the rotary driving assembly of the cryogenic storage tank drives the rotating frame to rotate, thereby driving the basket on the rotating frame to move in the circumferential direction to the position corresponding to the storage door of the cryogenic storage tank;
  • step T2 the lifting member lifts the basket, so that the tray of the cryotube on the basket is lifted to a position where the scooping assembly can scoop it through the storage door.
  • the method further includes step G: directly transporting the storage box through a transport vehicle provided with a container.
  • the biological sample storage is convenient for overall transportation, convenient installation, strong field adaptability and strong expandability;
  • the present invention has the following second beneficial effect: a storage method capable of rapid storage, guaranteeing the entire cold chain storage, fast and accurate sort storage, high efficiency, and greatly reducing labor costs.
  • Figure 1 is a schematic diagram of a biological sample storage structure
  • Figure 2 is a schematic diagram of the decomposition of the biological sample storage structure
  • Figure 3 is a top view of a biological sample storage
  • Figure 4 is a schematic diagram of the internal structure of the deep and low temperature storage tank
  • Figure 5 is a cross-sectional view of a deep and low temperature storage tank
  • Figure 6 is a schematic diagram of the structure of the rotating frame and the lifting member
  • FIG. 7 is a schematic structural view of the basket from the rear view direction
  • FIG. 10 is a schematic diagram of the structure of the rotary drive assembly and the lift drive motor
  • Figure 11 is a schematic diagram of the structure of an automatic transfer mechanism
  • Figure 12 is a schematic diagram of the internal structure of the automatic transfer mechanism
  • Figure 13 is a schematic diagram of the structure of the shoveling component and the manipulator
  • 2-Cryogenic storage tank 201-carry basket; 202-tray support; 203-freezer tube tray; 204-storage door; 205-rotation rack; 206-storage area; 207-lifting member; 208-rotation drive assembly; 209-lift operation channel; 2010-push receiving block; 2011-transition axial groove; 2012-partition plate; 2013-lift sleeve; 2014-lift drive motor; 2015-lift driving wheel; 2016-lift driven wheel; 2017 -Lifting transition wheel; 2018-lifting table; 2019-lifting transition plate; 2020-lifting conveyor belt; 2022-storage guide sliding track; 2023-basket slide bar; 2024-rotating action shaft; 2025-receiving slot; 2026-rotating drive motor ; 2027-rotating drive shaft; 2028-clamping parts; 2029-supporting bar; 2030-storage tube slot;
  • 301-shoveling assembly 3011-shoveling box; 3012-shoveling first drive; 3014-shoveling sliding base; 3015-sliding guide plate; 3016-shovel tray assembly; 3017-temporary storage rack; 3018-shovel Feeding port; 3019-shovel feeding nitrogen hole; 30110-left sliding seat; 30111-right sliding seat; 30112-base frame; 30113-left sliding guide rail; 30114-right sliding guide rail; 30115-sliding plate; 30116- Shovel left slide; 30117- Shovel right slide; 30118- Shovel; 30119-Slide support plate; 30120-Pulley; 30121- Shovel drive motor; 30122-Screw; 30123-Screw nut; 30124-Shovel Send and receive port;
  • This embodiment provides a kind of biological sample storage, including a storage box 1, a plurality of cryogenic storage tanks 2 and an automatic transfer mechanism 3; the at least one cryogenic storage tank 1 and the automatic transfer mechanism 3 are both provided in the Inside the storage box 1; the storage box 1 is provided with a transfer window 101, and the automatic transfer mechanism 3 can receive the transfer tank 4 with the frozen storage tube transferred from the outside through the transfer window 101; The automatic transfer mechanism 3 can transfer the frozen storage tube in the received transfer tank 4 to the cryogenic storage tank 2.
  • a storage box 1 is provided, a plurality of deep and low temperature storage tanks 2 are provided in the storage box 1, and an automatic operating mechanism 3 is provided between the multiple deep and low temperature storage tanks 2.
  • the low-temperature storage tank 2 moves between, and the automatic transfer mechanism 3 can correspond to the transfer window 101 of the storage box body 1, the transfer tank 4 with a cryotube enters the automatic transfer mechanism 3 through the transfer window 101, the automatic transfer mechanism 3 Carry the transfer tank 101 to the corresponding cryogenic storage tank 2 and transfer the frozen storage tube of the transfer tank 101 into the cryogenic storage tank 2 for storage; of course, there is a control system provided here for the cryogenic storage tank 2 and automatic transfer
  • the operation of the mechanism 3 is controlled; setting a nitrogen supply system not only supplies nitrogen to the cryogenic storage tank 2 to maintain a low temperature state, but also continuously supplies nitrogen to the automatic operation mechanism 3 to keep it in a cryogenic state.
  • the biological sample storage tank of the present invention is arranged in the storage tank box, which is convenient for on-site installation, strong adaptability and strong expandability; the deep storage tank box can be set according to the needs of the scene The number and location of low-temperature storage tanks; when transporting them, it is also convenient to transport, just use the storage box for transportation; 2. Change the destructive risk brought by the manual storage process in the existing technology, The transfer tank or cryopreservation tube has been kept in a low temperature environment, which greatly reduces the destructive risk during storage; 3. No need to enter the warehouse manually, there is a storage box directly to receive the transfer tank.
  • the automatic transfer mechanism transfers the transfer tank ,
  • the deep and low temperature storage tanks corresponding to the transfer tanks can be docked quickly, corresponding to the classification storage, and they are accurate and efficient, which greatly reduces the risk; 4.
  • the automatic transfer mechanism When the automatic transfer mechanism is docked with the deep and low temperature storage tanks, it can only be Open the corresponding size of the transfer tank that can be stored, and the storage is quick and in place, avoiding the manual opening of the deep and low temperature storage tank for storage.
  • Risk-temperature storage tank inside the cold storage environment will be destroyed, greatly reducing nitrogen consumption, strong stability; 5, reduce the impact of the interaction between exercise and risk of sample contamination each other; 6, the follow-up to its maintenance is very convenient.
  • This embodiment further discloses a structure in which the automatic transfer mechanism 3 is docked with the cryogenic storage tank 2 to transport and store frozen tubes;
  • the cryogenic storage tank 2 is provided with a movable basket 201, and the basket 201
  • a plurality of tray supports 202 are provided therein, and the tray support 202 supports a cryotube tray 203;
  • the cryogenic storage tank 2 is provided with a storage door 204, and each of the tray supports 202 can follow Move the carrying basket 201 to move to a position corresponding to the storage door 204;
  • the automatic transfer mechanism 3 includes a shoveling assembly 301 that can pass through the storage door 204 to freeze the frozen basket 201
  • the storage tube tray 203 is shoveled to receive or may shovel the received frozen storage tube tray 203 back into the carrying basket 201.
  • the docking method of the automatic transfer mechanism 3 and the cryogenic storage tank 2 can also be sucked or grabbed by a robot, or the basket can be directly moved out of the cryogenic storage tank 2 and docked with the automatic transfer mechanism 3, etc.
  • a stable and effective conveying method even if the conveying achieves the conveying purpose, there is no preferred method of the shoveling assembly in this embodiment, which is more stable, more efficient, and has no impact on the environment.
  • four deep and low temperature storage tanks 2 are provided in the storage box 1, and an automatic transfer rail 8 is provided between the four deep and low temperature storage tanks 2, and the automatic transfer mechanism 3 is on the automatic transfer rail 8. Move up to achieve the purpose of moving between 4 deep and low temperature storage tanks 2.
  • the shoveling assembly 301 includes a shoveling box 3011, a shoveling first driving member 3012, a shoveling second driving member, and a shoveling sliding base 3014.
  • the shoveling box 3011 is provided with a shoveling and conveying port 3018, and the shoveling and conveying port 3018 can be connected with the cryogenic storage tank 2
  • the temporary storage rack 3017 and the scooping sliding base 3014 are both disposed in the scooping box 3011, and the sliding guide plate 3015 is slidably disposed on the scooping sliding base 3014
  • the shovel plate assembly 3016 is slidably disposed on the sliding guide plate 3015;
  • the temporary storage rack 3017 can temporarily store the transfer tank 4;
  • the shoveling box body 3011 is provided with a shoveling and passing nitrogen Hole 3019, the scooping nitrogen hole 3019 communicates with
  • the automatic transfer mechanism 3 first temporarily stores the transfer tank 4 received from the transfer window 101 of the storage box 1 in the temporary storage rack 3017, and provides a scooping box body 3011, and a scooping box nitrogen is opened on the scooping box body 3011. Hole 3019, the shovel feeding nitrogen hole 3019 communicates with the nitrogen supply system, which ensures that the shovel box 3011 is continuously supplied with nitrogen, which keeps it in a deep low temperature state, and the received transfer tank 4 is also immediately in In the process of the deep cryogenic state; the intermediate transfer tank 4 is temporarily stored in the temporary storage rack 3017, the automatic transfer mechanism 3 has moved to the position corresponding to the cryogenic storage tank 2, the shoveling delivery port 3018 and the cryogenic storage tank 2 Corresponding to the storage door 204; the first shovel driving member 3012 drives the sliding guide plate 3015 to move toward the shovel transport port 3018, and then the second shovel driving member 3013 drives the shovel plate assembly 3016 to move out of the shovel transport port 3018 extends into the cryogenic storage tank 2 to shovel out
  • This setting 1. Makes the whole process in a deep and low temperature environment, greatly improving the safety of biological samples; 2.
  • the temporary storage rack provides a temporary storage location for the transfer tank, which is convenient for extracting the frozen storage tube in the transfer tank; 3.
  • Shovel The feeding component has high stability during the shoveling process.
  • the scooping sliding base 3014 includes a left sliding seat 30110, a right sliding seat 30111, and a base frame 30112.
  • the left sliding seat 30110 and the right sliding seat 30111 are respectively disposed on the left and right sides of the base frame 30112;
  • the sliding guide plate 3015 includes a left sliding guide rail 30113, a right sliding guide rail 30114, and a sliding plate 30115;
  • the left sliding guide rail 30113 and the right sliding guide rail 30114 are respectively provided on the left and right ends of the sliding plate 30115;
  • the shovel plate assembly 3016 includes a left blade 30116, a right blade 30117 and a blade 30118; the left blade 30116 and the right blade 30117 are disposed on the left and right sides of the blade 30118;
  • the outer side of the left sliding guide rail 30113 slides on the left sliding base 30110, and the outer side of the right sliding guide rail 30114 slides on the right sliding base 30111, Said shovel pan left slider 30 116 on the inside of the left sliding guide rails 30 113 slides, sliding on the inner side of the shovel pan right sliding member 30117 of the right slide guide rails 30114.
  • the left sliding seat 30110 includes a sliding support plate 30119 and a plurality of pulleys 30120, and the plurality of pulleys 30120 are arranged on the sliding support plate 30119 in a row;
  • the right sliding seat 30111 has the same structure as the left sliding seat 30110 And the symmetrical setting;
  • the left sliding guide rail 30113 is in the shape of an "I", the right sliding guide rail 30114 and the left sliding guide rail 30113 have the same structure and are symmetrically arranged;
  • the first driving member 3012 includes a shovel A driving motor 30121 and a screw 30122, a screw nut 30123 is provided on the lower end surface of the sliding plate 30115, the screw nut 30123 is screw-connected with the screw 30122, and the motor shaft of the shovel driving motor 30121 and the wire The bar 30122 is connected.
  • the shovel driving motor of the shoveling first driving member 3012 drives the screw 30122 to rotate, and the screw 30122 is screw-connected with the screw nut 30123, the rotary motion is converted into linear motion, and the sliding plate 30115 is driven to move linearly; the left sliding guide
  • the rail 30113 is formed in an "I" shape structure, so that one end of the left sliding guide rail 30113 and a plurality of pulleys 30120 of the left sliding seat 30110 cooperate to slide on the sliding support plate 30119; meanwhile, the other side end of the "I" shape
  • the sliding track of the left slider 30116 of the shovel is formed, so that the left sliding piece 30116 of the shovel is slid thereon; the right sliding guide rail 30114 and the left sliding guide rail 30113 have the same structure and are symmetrically arranged; this arrangement is in space ratio While compact in structure and stable in operation, it also provides sufficient retractable length of the scooping assembly 301.
  • the automatic transfer mechanism 3 further includes a code scanning member 302, and the code scanning member 302 can scan the cryopreservation tube to be transferred.
  • the automatic transfer mechanism 3 After receiving the transfer tank 4, the automatic transfer mechanism 3 temporarily stores the transfer tank 4 through the temporary storage rack 3017, and then extracts the frozen storage tube from the transfer tank 4, and then moves the frozen storage tube to the scanning member 302.
  • the cryopreservation tube is scanned, and then shoveled into the cryogenic storage tank 2; in this way, the scancode processes, analyzes, and stores the information of the cryopreservation tube, realizing high-standard automation.
  • the scanning member 302 includes a scanner 3021 and a scanning mirror surface 3022.
  • a scanner mounting slot 3023 can be provided in the automatic transfer mechanism 3, and the scanner 3021 can be installed in the scanner mounting slot 3023.
  • a scanning mirror surface 3022 is covered above the encoder mounting groove 3023; this is convenient for scanning codes.
  • the automatic transfer mechanism 3 further includes a transfer receiving box 303 and a manipulator 304 ;
  • the transfer receiving box 303 and the scooping box 3011 are arranged side by side, the manipulator 304 is provided above the scooping assembly 301 and the transfer receiving box 303; the transfer receiving box 303 receives The transfer tank 4 conveyed from the transfer window 101; the manipulator 304 can grab the transfer tank 4; the shoveling box 3011 has a shoveling receiving opening 30124 on the upper end surface, and the manipulator 304 can move To the position corresponding to the scooping receiving port 30124.
  • the transfer receiving box 303 is provided with a first opening 3031 and a second opening 3032.
  • the first opening 3031 is provided corresponding to the transfer window 101, and the second opening 3032 is opened on the upper end surface of the transfer receiving box 303 ,
  • a transfer upper cover 3033 can be provided at the second opening 3032; the first opening 3031 receives the transfer tank 4, the transfer window 101 is closed, the transfer upper cover 3033 at the second opening 3032 is opened, and the manipulator 304 grabs through the second opening 3032
  • the transfer tank 4 is put into the temporary storage rack 3017, the shoveling assembly 301 scoops the cryotube tray 203 into the shovel box 3011 of the automatic transfer mechanism 3, and the robot 304 puts the frozen storage in the transfer tank 4 on the temporary storage rack 3017 Pipe grab; first grab to the code scanning member, scan the code, process and store the information of the frozen storage tube; the robot 304 moves the frozen storage tube to the shovel receiving port 30124, and put the frozen storage tube in Go to the corresponding cryotube tray 203
  • the automatic transfer mechanism 3 further includes a transfer housing 305;
  • the manipulator 304 includes a grip drive assembly 3041, a Z-axis sleeve 3042, a Z-axis rod 3043, a Y-axis guide 3044, and a first X
  • the shaft guide 3045, the second X-axis guide 3046, the can grasping mechanism 3047, and the pipe-taking member 3048; the first X-axis guide 3045 and the second X-axis guide 3046 are distributed and fixed on both sides of the transfer housing 305.
  • the first X-axis guide 3045 and the second X-axis guide 3046 are slidably disposed on both sides of the Y-axis guide rail 3044;
  • the Z-axis sleeve 3042 is vertically arranged, and the middle of the Z-axis sleeve 3042 is slidable Disposed on the Y-axis guide rail 3044;
  • the Z-axis rod 3043 is slidably disposed in the Z-axis sleeve 3042, the lower end of the Z-axis rod 3043 is provided with a Z-bearing connector 3049, and the gripping tank
  • Both the mechanism 3047 and the pipe-removing member 3048 are respectively provided on the Z-bearing connector 3049;
  • the tank grasping mechanism 3047 can grasp the transfer tank 4, and the pipe-removing member 3048 can carry out freezing pipe storage;
  • the driving assembly 3041 drives the movement of the Z-axis sleeve 3042, the Y-axis guide 3044, and
  • the two ends of the Y-axis guide 3044 can slide along the first X-axis guide 3045 and the second X-axis guide 3046 to realize movement in the X-axis direction;
  • the Z-axis sleeve can slide on the Y-axis guide 3044 to realize Y The movement in the axis direction;
  • the Z-axis rod 3043 can move up and down in the Z-axis sleeve 3042 in the vertical direction to realize the movement in the Z-axis direction;
  • a Z-bearing connector 3049 is provided at the lower end of the Z-axis rod 3043 As shown in FIG.
  • a can grasping mechanism 3047 and a pipe taking member 3048 are respectively provided at the left and right ends of the Z bearing connector 3049, the can grasping mechanism 3047 can grasp the transfer tank 4, and the taking pipe member 3048 can be stored frozen Take the tube; first use the canning mechanism 3047 to grab the transfer tank 4 onto the temporary storage rack 3017, and open the canister cover of the transfer tank 4, here the canister can be grabbed and opened by the canning mechanism 3047, or through Other opening methods will not be repeated here; after opening the tank lid, the pipe-taking part grabs the pipe-taking part 3048 in the transfer tank 4, and then scans the code to grab the cryotube tray 203 and other subsequent actions.
  • the preferred embodiment of the cryogenic storage tank 2 in this embodiment is to first rotate the rotating frame 205 to store The basket 201 in the area 206 is rotated to a corresponding position, and then the lifting basket 207 is used to extract the basket 201 to the position corresponding to the storage door 204;
  • the deep cryogenic storage tank 2 of the present invention is designed to be in a limited space, and The storage space can be fully utilized, and the entire basket 201 is not lifted, but the required cryotube tray 203 is operated to correspond to the storage door 204.
  • the deep cryogenic storage tank 2 is provided There are a rotating frame 205, a rotating driving assembly 208 and a lifting member 207; the lifting member 207 is nested in the rotating frame 205, and the upper part of the lifting member 207 is fixed with the tank body of the cryogenic storage tank 2
  • the rotary drive assembly 208 drives the rotating frame 205, which can cause the rotating frame 205 to rotate around the lifting member 207 in the cryogenic storage tank 2;
  • the rack 205 is divided into a plurality of storage areas 206 by a plurality of dividing plates, and each storage area 206 is provided with a lifting operation channel 209, and each of the lifting operation channels 209 communicates with the lifting member 207;
  • the storage A basket 201 is provided in the area 206; a push receiving block 2010 is provided on the periphery of the basket 201, and the push receiving block 2010 extends through the lifting operation channel 209 to a position corresponding to the lifting member 207
  • the lifting member 207 can drive the basket 201
  • the lifting member 207 is nested in the rotating frame 205, which greatly saves space and can save a large amount of space to be set as a storage area 206; further, the rotating frame 205 is recessed with a transition axial groove 2011 at the middle A plurality of partition plates 2012 extend outward from the periphery of the transitional axial groove 2011, and a plurality of lifting operation channels 209 are opened on the circumferential groove wall of the transitional axial groove 2011;
  • the storage areas 206 divided by the partition plate 2012 correspond to each other;
  • the lifting member 207 includes a lifting sleeve 2013, a lifting drive motor 2014, a lifting driving wheel 2015, a lifting driven wheel 2016, a lifting transition wheel 2017, and a lifting table 2018;
  • the lifting sleeve 2013 is provided in the transitional axial groove 2011 and can rotate relative to the rotating frame 205; the upper circumference of the lifting sleeve 2013 extends outwardly with a lifting transition plate 2019, and the lifting transition plate 2019 is used to lift the member 207 is
  • the lifting driving wheel 2015 here is preferably a sector-shaped gear and a sector-shaped lifting transition wheel 2017 arc-shaped meshing, which is the most torque-saving form; the lower end of the lifting sleeve 2013 is provided with a lifting driven wheel 2016, so A lifting conveyor belt 2020 is provided between the lifting driven wheel 2016 and the lifting transition wheel 2017; a lifting platform 2018 is provided on the lifting transmission belt 2020, and the lifting platform 2018 corresponds to the pushing receiving block 2010.
  • each storage area 206 rotates in the axial direction, and the basket 201 rotates with the storage area 206; because the lifting operation channel 209 is opened on the transitional axial groove 2011, that is, opened On the rotating rack 205, a push receiving block 2010 is extended outward from the basket 201 of each storage area 206, which not only ensures the stability of the basket 201 in the circumferential direction with the storage area 206 rotating, but also, when the corresponding When the basket 201 is lifted, the basket 201 stops at the position corresponding to the lifting member 207.
  • the lifting member 207 always maintains the position corresponding to the storage door 204 in the circumferential direction; the lifting drive motor 2014 drives the lifting driving wheel 2015 and drives the lifting transition wheel 2017 , So as to drive the lifting conveyor 2020 to move on the lifting transition wheel 2017 and the lifting driven wheel 2016; because the actual position of the lifting table 2018 is always lower than the position of the push receiving block 2010 extending from the basket 201 to the lifting operation channel 209, so when lifting When the conveyor belt 2020 moves, the lifting platform 2018 on the lifting conveyor belt 2020 will push it upward when it moves to push the receiving block 2010 Basket 201 so as to drive the lifting operation along path 209 do upward motion until needed vial tray 203 to the position corresponding to the movement of the door 204 is stored.
  • a further preferred implementation of this embodiment is that the partition plate 2012 is provided with a storage guide sliding rail 2022, and the basket 201 is also provided with a basket slide bar 2023 that cooperates with the storage guide sliding rail 2022.
  • the basket slider 2023 slides on the storage guide slide rail 2022. Enhance the stability of the lifting movement of the basket 201.
  • the lifting sleeve 2013 is a hollow inner sleeve; the center of the groove bottom of the transitional axial groove 2011 extends inside the lifting sleeve 2013 with a rotating action shaft 2024, which rotates
  • the upper end of the shaft 2024 is provided with a "ten" receiving groove 2025;
  • the rotary drive assembly 208 includes a rotary drive motor 2026 and a rotary drive shaft 2027, the rotary drive motor 2026 is fixed outside the cryogenic storage tank 2, and the The motor shaft of the rotary drive motor 2026 is coaxially connected to the rotary drive shaft 2027.
  • a "ten" snap fitting 2028 is provided at the lower end of the rotary drive shaft 2026, and the snap fitting 2028 of the rotary drive shaft 2027 is engaged in receiving In the slot 2025.
  • the basket 201 is fan-shaped, and a plurality of support bars 2029 are provided on both sides of the basket 201, and each two support bars 2029 on the same horizontal plane form the tray support Piece 202.
  • the cryotube tray 203 has a fan shape matching the basket 201, and the cryotube tray 203 is provided with a plurality of tube storage slots 2030.
  • the bottom of the groove is a developed bottom.
  • the open trough bottom described here is provided with an open hole at the bottom of the trough.
  • a preferred further implementation of this embodiment further includes an access door 5, a nitrogen supply system, and a dehumidification system.
  • the access door 5 is provided on the storage box 1, and the storage box 1 can be opened through the access door 5. Repair the interior; the nitrogen supply system can supply nitrogen in the storage box 1 or the automatic transfer mechanism; the dehumidification system can dehumidify the storage box 1, the dehumidification system includes Multiple dehumidifiers 7. It is easy to maintain and can be replaced quickly in case of failure.
  • This embodiment provides a storage method for a biological sample storage warehouse.
  • a transfer tank with a cryotube is directly placed in the storage warehouse through the transfer window of the storage cabinet; in step S, the The automatic transfer mechanism automatically transfers the frozen storage tube in the received transfer tank to the cryogenic storage tank.
  • This storage method eliminates the risk of damage to the environment of the cryotube caused by manual storage in the prior art, and is convenient, efficient, and accurate.
  • step S1 the robot of the automatic transfer mechanism grabs the transfer tank received by the storage to the set temporary storage rack;
  • Step S2 while performing step S1 or after step R above, the automatic transfer mechanism will move along the designated line to the corresponding cryogenic storage tank;
  • Step S3 the storage door of the cryogenic storage tank is opened, and the shoveling assembly of the automatic transfer mechanism shovels the tray of the cryotube in the cryogenic storage tank onto the platform corresponding to the automatic transfer mechanism;
  • Step S4 the manipulator grabs the frozen storage tube in the transfer tank on the temporary storage rack and places it on the frozen storage tube tray;
  • step S5 the shoveling component transports the cryotube drag tray back to the deep and low temperature storage tank.
  • the automatic transfer mechanism can be used to move between multiple cryogenic storage tanks, which replaces the process of manually searching for docking in multiple cryogenic storage tanks in the prior art, and makes the cryogenic storage tanks more convenient for classification settings. Greatly improve the storage efficiency.
  • the connection between the automatic transfer mechanism and the cryogenic storage tank is carried out by shoveling, which greatly improves the efficiency of storing the cryotube in the cryogenic storage tank.
  • the manipulator grabs the cryotube from the temporary storage rack to the top of the code scanning member to scan the QR code on the cryotube.
  • the control system processes and stores the scanning results, and then grabs the cryotubes on the cryotube tray.
  • step T before the step S3 is performed, the corresponding basket in the cryogenic storage tank moves to a position corresponding to the storage door;
  • the T step is divided into:
  • step T1 the rotary driving assembly of the cryogenic storage tank drives the rotating frame to rotate, thereby driving the basket on the rotating frame to move in the circumferential direction to the position corresponding to the storage door of the cryogenic storage tank;
  • step T2 the lifting member lifts the basket, so that the tray of the cryotube on the basket is lifted to a position where the scooping assembly can scoop it through the storage door.
  • a preferred further implementation of this embodiment further includes step G: directly transport the storage box body through a transport vehicle provided with a container. It can be transported by one container, which is convenient to install and adaptable and expandable on site.

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Abstract

一种生物样本储存库，包括储存库箱体（1）、多个深低温储存罐（2）及自动转运机构（3）；至少一个深低温储存罐（2）及自动转运机构（3）均设置在储存库箱体（1）内；储存库箱体（1）上开设有传递窗（101），自动转运机构（3）接收从外部通过传递窗（101）传送来的存有冻存管的中转罐（4）；且自动转运机构（3）将接收到的中转罐（4）内的冻存管转送到深低温储存罐（2）内；解决现有技术中生物样本储存库无法保证全冷链保护的问题，给生物样本的储存提高破坏风险的问题，以及解决现有技术中的深低温储存罐运输非常不方便的问题；还提出了一种生物样本储存库的储存方法。

Description

一种生物样本储存库及其储存方法
 
技术领域
本发明涉及生物样本储存设备领域，尤其涉及一种生物样本储存库及其储存方法。
 背景技术
生物样本库是标准化收集、处理、储存健康和疾病生物体的生物大分子、细胞、组织和器官等样本的设备。生物样本在存储前，需要经过程序降温使其休眠，然后存入液氮容器或深低温冰箱内。对于某些特定的生物样本，其存储过程需要保证全冷链保护，全程都需要处于深低温环境中，以保护其生物活性，避免反复冻融的损伤。
现有的储存库均是在一固定仓房内设放多个深低温储存罐，需要对冻存管进行储存或调取时，人工进入仓房内，找到相对应类别存放的深低温储存罐进行人工存放；在对生物样本进行储存时，人工进入仓房，打开深低温储存罐将冻存管从中转罐中冻存管放入到深低温储存罐内；这里需要进一步说明的是，生物样本在最开始被提取时，将其放入到冻存管内，为了方便转移运输，将冻存管放入到中转罐中。现有技术对冻存管的储存，是通过人工操作的，有较多的局限性：1.人工在储存过程中，使得储存的过程冻存管或中转罐一直处于非低温环境中，给生物样本带来了较大的破坏性风险；2,人工储存进入仓房，需要先找到生物样本的所属的分类的深低温储存罐，然后再将其存放进去，效率低，人工成本高，不易分类储存，风险大；3.人工在打开深低温储存罐进行冻存管的储存时，深低温储存罐开口的大小必须符合人的操作度的大小，这个过程打开深低温储存罐对其本身温度的影响有破坏性，以深低温储存罐为液氮罐为例，这样操作耗氮量会很大；4.人工储存易产生样本互相运动间的影响及互相污染，风险高；5.现有的仓房式设置方式，不方便安装，运输，现场适应性差；6.后续对深低温储存仓房的维护保养，非常不方便。
这种方式无法保证冻存管在储存或调取整个过程中保证全冷链保护；不仅对冻存管内的生物样本产生很大破坏风险，对某些特定的生物样本，在对全冷链保护要求高时，现有技术的这种储存方式看来是不可取的；
当需要对生物样本分类整体转移时，也非常不方便；深低温储存罐本身体积较大，在对深低温储存罐进行设置运输时，也非常的不方便；
总之现有技术储存方式不佳，存取管较为不便，为使用者带来不便。
 技术问题
本发明的一个目的是提供一种生物样本储存库，解决现有技术中的生物样本储存库无法保证全冷链保护的问题，给生物样本的储存提高破坏风险的问题，解决现有技术中的深低温储存罐运输非常不方便的问题。
本发明的另一个目的是提供生物样本储存库的储存方法，解决现有技术中的储存方式不便捷，不能保证全程冷链保护，储存效率低，运输不方便的问题。
 技术解决方案
本发明解决第一个技术问题采用如下技术方案：一种生物样本储存库，包括储存库箱体、多个深低温储存罐及自动转运机构；所述至少一个深低温储存罐及自动转运机构均设置在所述储存库箱体内；所述储存库箱体上开设有传递窗，所述自动转运机构可接收从外部通过传递窗传送来的存有冻存管的中转罐；且所述自动转运机构可将接收到的中转罐内的冻存管转送到所述深低温储存罐内。
优选的，所述深低温储存罐内设置有可移动位置的提篮，所述提篮内设置有多个托盘支撑件，所述托盘支撑件上撑托有冻存管托盘；所述深低温储存罐设置有储存门，每个所述托盘支撑件均可随着提篮的移动，从而移动到与所述储存门相对应的位置； 所述自动转运机构包括铲送组件，所述铲送组件可穿过储存门将提篮内的冻存管托盘铲起接收或可将接收的冻存管托盘铲送回提篮内。
优选的，所述铲送组件包括铲送盒体、铲送第一驱动件、铲送第二驱动件、铲送滑动底座、滑动导向板、铲盘组件及暂存架；所述铲送盒体上开设有铲送输送口，且所述铲送输送口可与所述深低温储存罐的储存门相对应；所述暂存架及所述铲送滑动底座均设置在所述铲送盒体内，所述滑动导向板可滑动的设置在所述铲送滑动底座上，所述铲盘组件可滑动的设置在所述滑动导向板上；所述暂存架可对中转罐进行暂存；所述铲送盒体上开设有铲送通氮孔，所述铲送通氮孔与供氮系统连通；所述铲送第一驱动件对所述滑动导向板的滑动进行驱动，所述铲送第二驱动件对铲盘组件的滑动进行驱动。
优选的，所述铲送滑动底座包括左滑动座、右滑动座及底座框架，所述左滑动座与右滑动座分别设置在所述底座框架的左右两侧；
所述滑动导向板包括左滑动导向轨道、右滑动导向轨道及滑动板；所述左滑动导向轨道及右滑动导向轨道分别设置在所述滑动板的左右两侧端；
所述铲盘组件包括铲盘左滑动件、铲盘右滑动件及铲盘；所述铲盘左滑动件及铲盘右滑动件设置在所述铲盘的左右两侧；
所述左滑动导向轨道的外侧在所述左滑动座上滑动，所述右滑动导向轨道的外侧在所述右滑动座上滑动，所述铲盘左滑动件在所述左滑动导向轨道的内侧上滑动，所述铲盘右滑动件在所述右滑动导向轨道内侧上滑动。
优选的，所述左滑动座包括滑动支撑板和多个滑轮，所述多个滑轮成一排设置在所述滑动支撑板上；所述右滑动座与所述左滑动座结构相同且对称设置；
所述左滑动导向轨道成“工”字形，所述右滑动导向轨道与所述左滑动导向轨道结构相同且对称设置；
所述铲送第一驱动件包括铲送驱动电机及丝杠，所述滑动板下端面上设置有丝杠螺母，所述丝杠螺母与丝杠螺纹连接，所述铲送驱动电机的电机轴与所述丝杠连接。
优选的，所述自动转运机构还包括扫码构件，所述扫码构件可对其转运的冻存管进行扫码。
优选的，所述自动转运机构还包括转运接收箱体及机械手；
所述转运接收箱体与所述铲送盒体并排设置，所述机械手设置在所述铲送组件与所述转运接收箱体的上方；
所述转运接收箱体接收从所述传递窗输送进来的中转罐；所述机械手可对中转罐进行抓取；
所述铲送盒体上端面上开设有铲送接收口，所述机械手可移动到与铲送接收口相对应的位置。
优选的，所述自动转运机构还包括转运外壳；所述机械手包括抓取驱动组件、Z轴套、Z轴杆、Y轴导轨、第一X轴导轨、第二X轴导轨、抓罐机构及取管件；
所述第一X轴导轨及第二X轴导轨分布固定在所述转运外壳的两侧端，所述Y轴导向轨的两侧端可滑动的设置所述第一X轴导轨及第二X轴导轨上；所述Z轴套竖直设置，且Z轴套的中部可滑动的设置在所述Y轴导向轨上；
所述Z轴杆可滑动的设置在所述Z轴套内，所述Z轴杆的下端设置有Z轴承接件，所述抓罐机构及取管件均分别设置在所Z轴承接件上；
所述抓罐机构可对中转罐进行抓取，所述取管件可对冻存管进行取管；
所述抓取驱动组件分别对所述Z轴套、Y轴导轨及Z轴杆的运动进行驱动。
优选的，所述深低温储存罐内设置有旋转架、旋转驱动组件及提升构件；
所述提升构件嵌套在所述旋转架内，且所述提升构件的上部与所述深低温储存罐的罐体相固定；所述旋转驱动组件对旋转架进行驱动，可使得旋转架在深低温储存罐内围绕所述提升构件进行旋转；
所述旋转架被多个分割板分割成多个储存区，所述储存区上均开设有提升操作通道，所述每个提升操作通道均与所述提升构件相贯通；
所述储存区内设置有提篮；所述提篮外围向外延伸设置一推动接收块，且所述推动接收块穿过所述提升操作通道延伸至与所述提升构件相对应的位置；
所述提升构件可通过对推动接收块的作用驱动提篮沿提升操作通道在储存区内做升降运动。
优选的，所述旋转架上方中部向下凹设有过渡轴向槽，所述过渡轴向槽的外围向外延伸设置有多个分隔板，且所述过渡轴向槽的周向槽壁上开设有多个提升操作通道；所述提升操作通道与分隔板分成的储存区一一对应；
所述提升构件包括提升套筒、提升驱动电机、提升主动轮、提升从动轮、提升过渡轮及提升台；
所述提升套筒设置在所述过渡轴向槽内，且可与旋转架相对旋转；所述提升套筒的上部圆周向外延伸有提升过渡板，所述提升驱动电机设置在所述深低温储存罐外部，且所述提升驱动电机的电机轴向下延伸依次穿过深低温储存罐的罐盖及提升过渡板设置有提升主动轮；
所述提升套筒外围上端设置有提升过渡轮与所述提升主动轮啮合连接，所述提升套筒外围下端设置有提升从动轮，所述提升从动轮与所述提升过渡轮之间设置有提升传送带；所述提升传动带上设置有提升台，所述提升台与所述推动接收块相对应。
优选的，所述分隔板上设置有储存导向滑行轨道，所述提篮外围也设置有与所述储存导向滑行轨道向配合的提篮滑条，所述提篮滑条在所述储存导向滑行轨道上滑动。
优选的，所述提升套筒为内部中空的管套；
所述过渡轴向槽的槽底中心处向提升套筒内部延伸设有旋转作用轴，旋转作用轴上端设置有“十”字接收槽；
所述旋转驱动组件包括旋转驱动电机和旋转驱动轴，所述旋转驱动电机固定在所述深低温储存罐外部，且所述旋转驱动电机的电机轴与所述旋转驱动轴同轴连接，所述旋转驱动轴下端设置有“十”字卡接件，且旋转驱动轴的卡接件卡合在接收槽内。
优选的，所述提篮成扇形，且所述提篮内的两侧设置有多个支撑条，每两条在同一水平面上的支撑条形成所述的托盘支撑件。
优选的，所述冻存管托盘为与提篮相契合的扇形，且所述冻存管托盘上设置有多个存管槽，所述存管槽的槽底为开发式槽底。
优选的，还包括检修门、供氮系统及除湿系统，所述检修门设置在所述储存库箱体上，可通过检修门打开储存库箱体，对其内部进行检修；
所述供氮系统可对储存库箱体内进行供氮，也可对自动转运机构内供氮；
所述除湿系统可对储存库箱体进行除湿。
本发明解决另一个技术问题采用如下技术方案：一种生物样本储存库的储存方法， R步骤,将存有冻存管的中转罐直接通过储存库箱体的传递窗放入到储存库中；S步骤,储存库中的自动转运机构将接收到的中转罐内的冻存管自动转送到所述深低温储存罐内。
优选的，S1步骤,自动转运机构的机械手将储存库接收的中转罐抓取到设定的暂存架上；
S2步骤，在进行S1步骤的同时或在上述R步骤之后，自动转运机构会沿着指定线路运动到相对应的深低温储存罐处；
S3步骤，深低温储存罐的储存门打开，自动转运机构的铲送组件对深低温储存罐内的冻存管托盘铲入到自动转运机构相对应的平台上；
S4步骤，机械手抓取暂存架上中转罐内的冻存管放置到冻存管托盘上；
S5步骤，铲送组件再将冻存管拖盘输送回深低温储存罐内。
优选的，在所述S4步骤进行时，机械手先从暂存架上将冻存管抓取至扫码构件上方对冻存管上的二维码进行扫码，设置的控制系统，对扫码结果进行处理及储存，之后再将冻存管抓取至冻存管托盘上。
优选的，T步骤,在所述S3步骤进行之前，深低温储存罐内的相对应的提篮移动到与储存门相对应的位置；
所述T步骤分为：
T1步骤，深低温储存罐的旋转驱动组件驱动旋转架旋转，从而带动旋转架上的提篮在周向上运动到深低温储存罐的储存门相对应的位置处；
T2步骤，提升构件将提篮提升，使其提篮上的冻存管托盘提升至铲送组件可穿过储存门对其铲送的位置。
优选的，还包括G步骤：将储存库箱体直接通过设有集装箱的运输车直接运输。
有益效果
本发明具有如下第一有益效果：
1、生物样本储存库方便整体运输，安装方便，现场适应性强，扩充性强；
2、储存的运行可靠效率高，储存量大；
3、储存方便、易分类；
4、节能，有效减少能源(液氮)消耗；
5、可减少样本相互运动间的影响及相互污染的风险；
6、维护保养方便，万一其有故障可快速更换。
本发明具有如下第二有益效果：能够快速储存，保证全程冷链储存，快速准确的分类储存，效率高，大大减少人工成本的储存方法。
 附图说明
图1为生物样本储存库结构示意图；
图2为生物样本储存库结构分解示意图；
图3为生物样本储存库俯视图；
图4为深低温储存罐内部结构示意图；
图5为深低温储存罐剖视图；
图6为旋转架与提升构件结构示意图；
图7为提篮从后视图方向的结构示意图；
图8为提篮从前视图方向的结构示意图；
图9为提升构件结构示意图；
图10为旋转驱动组件及提升驱动电机结构示意图；
图11为自动转运机构结构示意图；
图12为自动转运机构内部结构示意图；
图13为铲送组件与机械手结构示意图；
图14为铲送组件结构分解图。
图中标记示意为：
1-储存库箱体；101-传递窗；
2-深低温储存罐；201-提篮；202-托盘支撑件；203-冻存管托盘；204-储存门；205-旋转架；206-储存区；207-提升构件；208-旋转驱动组件；209-提升操作通道；2010-推动接收块；2011-过渡轴向槽；2012-分隔板；2013-提升套筒；2014-提升驱动电机；2015-提升主动轮；2016-提升从动轮；2017-提升过渡轮；2018-提升台；2019-提升过渡板；2020-提升传送带； 2022-储存导向滑行轨道；2023-提篮滑条；2024-旋转作用轴；2025-接收槽；2026-旋转驱动电机；2027-旋转驱动轴；2028-卡接件；2029-支撑条；2030-存管槽；
3-自动转运机构；
301-铲送组件；3011-铲送盒体；3012-铲送第一驱动件；3014-铲送滑动底座；3015-滑动导向板；3016-铲盘组件；3017-暂存架；3018-铲送输送口；3019-铲送通氮孔；30110-左滑动座；30111-右滑动座；30112-底座框架；30113-左滑动导向轨道；30114-右滑动导向轨道；30115-滑动板；30116-铲盘左滑动件；30117-铲盘右滑动件；30118-铲盘；30119-滑动支撑板；30120-滑轮；30121-铲送驱动电机；30122-丝杠；30123-丝杠螺母；30124-铲送接收口；
302-扫码构件；3021-扫描器；3022-扫码镜面；3023-扫码器安装槽；
303-转运接收箱体；3031-第一开口；3032-第二开口；3033-转运上盖；
304-机械手；3041-抓取驱动组件；3042- Z轴套；3043- Z轴杆；3044- Y轴导轨；3045-第一X轴导轨；3046-第二X轴导轨；3047-抓罐机构；3048-取管件；3049-Z轴承接件；
305-转运外壳；
4-中转罐；5-检修门；6-供氮系统；7-除湿机；8-自动转运轨道。
 本发明的最佳实施方式
下面结合实施例及附图对本发明的技术方案作进一步阐述。
实施例1
本实施例提供了种生物样本储存库，包括储存库箱体1、多个深低温储存罐2及自动转运机构3；所述至少一个深低温储存罐1及自动转运机构3均设置在所述储存库箱体1内；所述储存库箱体1上开设有传递窗101，所述自动转运机构3可接收从外部通过传递窗101传送来的存有冻存管的中转罐4；且所述自动转运机构3可将接收到的中转罐4内的冻存管转送到所述深低温储存罐2内。
设置一个储存库箱体1，在储存库箱体1内设置多个深低温储存罐2，在多个深低温储存罐2之间设置自动运转机构3，自动运转机构3不仅可以在多个深低温储存罐2之间移动，而且自动转运机构3可与储存库箱体1的传递窗101相对应，内有冻存管的中转罐4通过传递窗101进入自动转运机构3，自动转运机构3携带中转罐101运动至相对应的深低温储存罐2处，将中转罐101的冻存管转送进深低温储存罐2中进行储存；当然这里设置有控制系统，对深低温储存罐2及自动转运机构3的运作进行控制；设置供氮系统不仅对深低温储存罐2进行供氮保持低温状态，也可对自动运转机构3进行持续供氮，使其处在深低温状态。
本发明的生物样本储存库，1、这种将多个深低温储存罐设置在储存库箱体内，方便现场的安装，适应性强，扩充性强；可根据现场的需要设置储存库箱体内深低温储存罐的个数，位置等等；在对其运输时，也方便运输，直接利用储存箱体进行运输即可；2.改变了现有技术中人工储存过程中带来的破坏性风险，使得中转罐或冻存管一直处于低温环境中，大大降低了储存过程中的破坏性风险；3，不需要人工进入仓房，直接有储存库箱体接收中转罐由自动转运机构对中转罐进行转运，由中转罐对相对应的深低温储存罐对接，能够快速的对应分类储存，且准确，效率高，大大降低了风险；4、再自动转运机构在与深低温储存罐对接储存时，可只打开能够储存的中转罐相对应大小的口，而且储存的迅速，到位，避免了人工在打开深低温储存罐进行储存时，深低温储存罐内部低温储存环境会被破坏的风险，大大减少了耗氮量，稳定性强；5，减少样本互动运动间的影响及互相污染的风险；6、后续对其的维护保养非常方便。
本实施例进一步公开了一种自动转运机构3与深低温储存罐2对接输送及储存冻存管的结构方式；所述深低温储存罐2内设置有可移动位置的提篮201，所述提篮201内设置有多个托盘支撑件202，所述托盘支撑件202上撑托有冻存管托盘203；所述深低温储存罐2设置有储存门204，每个所述托盘支撑件202均可随着提篮201的移动，从而移动到与所述储存门204相对应的位置； 所述自动转运机构3包括铲送组件301，所述铲送组件301可穿过储存门204将提篮201内的冻存管托盘203铲起接收或可将接收冻存管托盘203铲送回提篮201内。为了保证自动转运机构3对冻存管转运的稳定性，也为了减少深低温储存罐2在与自动转运机构3对接时打开的储存门204尽可能小，保证了深低温储存罐2内部的深低温环境不受到影响，所以设置了与深低温储存罐2配合的铲送组件301，在深低温储存罐2内设置的可移动提篮201，提篮201设置多个托盘支撑件202，托盘支撑件202上撑托有冻存管托盘203，这样铲送组件301穿过储存门204，进入提篮201内相对应的冻存管托盘203进行铲出，铲到自动转运机构3内，然后自动转运机构3再将接收到的中转罐4内的冻存管放入到冻存管托盘203上，再将有冻存管的冻存管托盘203铲送回深低温储存罐2内；不仅保证了冻存管转运的稳定性，也尽可能的减少了在输送过程中对低温储存罐2的环境影响。当然，自动转运机构3与深低温储存罐2的对接方式也可以是通过机械手吸取或抓取，或将提篮直接移动出深低温储存罐2与自动转运机构3对接等等，这些方式都不能提供稳定的有效的传送方式，即使传送达到传送目的，也没有本实施例优选的铲送组件的方式更稳定，效率更高，也对环境没有影响。如图3所示，在储存库箱体1内设置4个深低温储存罐2，在4个深低温储存罐2之间设置自动转运轨道8，所述自动转运机构3在所述自动转运轨道8上运动，达到在4个深低温储存罐2之间运动的目的。
本实施例进一步公开了一种铲送组件301的具体实施方式，所述铲送组件301包括铲送盒体3011、铲送第一驱动件3012、铲送第二驱动件、铲送滑动底座3014、滑动导向板3015、铲盘组件3016及暂存架3017；所述铲送盒体3011上开设有铲送输送口3018，且所述铲送输送口3018可与所述深低温储存罐2的储存门204相对应；所述暂存架3017及所述铲送滑动底座3014均设置在所述铲送盒体3011内，所述滑动导向板3015可滑动的设置在所述铲送滑动底座3014上，所述铲盘组件3016可滑动的设置在所述滑动导向板3015上；所述暂存架3017可对中转罐4进行暂存；所述铲送盒体3011上开设有铲送通氮孔3019，所述铲送通氮孔3019与供氮系统连通；所述铲送第一驱动件3012对所述滑动导向板3015的滑动进行驱动，所述铲送第二驱动件对铲盘组件3016的滑动进行驱动。
自动转运机构3先将从储存库箱体1的传递窗101中接收的中转罐4先暂存在暂存架3017中，设置铲送盒体3011，铲送盒体3011上开设有铲送通氮孔3019，所述铲送通氮孔3019与供氮系统连通，这样保证了铲送盒体3011内不断的被供氮，使其一直处于深低温状态，接收到的中转罐4也马上处在了深低温状态中；当中转罐4暂存在暂存架3017中的过程中，自动转运机构3已经运动到与深低温储存罐2相对应的位置，铲送输送口3018与深低温储存罐2的储存门204相对应；所述的铲送第一驱动件3012驱动滑动导向板3015向铲送输送口3018方向运动，之后铲送第二驱动件3013驱动铲盘组件3016运动出铲送输送口3018伸入到深低温储存罐2中将对应的冻存管托盘203铲出，再缩回到起始位置；冻存管托盘203被带入到自动转运机构后，再将中转罐4中的冻存管放入到冻存管托盘204内；接收到冻存管之后的冻存管托盘203再通过铲送组件301铲送回深低温储存罐2中，进行储存；当然这里深低温储存罐2的储存门204的开门方式设置成上下滑动打开的方式，更方便的配合与自动转运机构3的对接。
这样设置1.使得整个过程处于深低温环境中，大大提高了生物样本的安全性；2.暂存架给中转罐提供了暂存的位置，方便提取中转罐中的冻存管；3.铲送组件在铲送过程中稳定性高。
在保证铲送过程运行稳定的同时，为了尽可能的减少铲送组件301的结构占用空间，使得结构紧凑，节省供氮能源，本实施例进一步优选公开了铲送组件301的进一步实施方式，所述铲送滑动底座3014包括左滑动座30110、右滑动座30111及底座框架30112，所述左滑动座30110与右滑动座30111分别设置在所述底座框架30112的左右两侧；所述滑动导向板3015包括左滑动导向轨道30113、右滑动导向轨道30114及滑动板30115；所述左滑动导向轨道30113及右滑动导向轨道30114分别设置在所述滑动板30115的左右两侧端；所述铲盘组件3016包括铲盘左滑动件30116、铲盘右滑动件30117及铲盘30118；所述铲盘左滑动件30116及铲盘右滑动件30117均设置在所述铲盘30118的左右两侧；所述左滑动导向轨道30113的外侧在所述左滑动座30110上滑动，所述右滑动导向轨道30114的外侧在所述右滑动座30111上滑动，所述铲盘左滑动件30116在所述左滑动导向轨道30113的内侧上滑动，所述铲盘右滑动件30117在所述右滑动导向轨道30114内侧上滑动。
所述左滑动座30110包括滑动支撑板30119和多个滑轮30120，所述多个滑轮30120成一排设置在所述滑动支撑板30119上；所述右滑动座30111与所述左滑动座30110结构相同且对称设置；所述左滑动导向轨道30113成“工”字形，所述右滑动导向轨道30114与所述左滑动导向轨道30113结构相同且对称设置；所述铲送第一驱动件3012包括铲送驱动电机30121及丝杠30122，所述滑动板30115下端面上设置有丝杠螺母30123，所述丝杠螺母30123与丝杠30122螺纹连接，所述铲送驱动电机30121的电机轴与所述丝杠30122连接。
所述铲送第一驱动件3012的铲送驱动电机驱动丝杠30122转动，丝杠30122与丝杠螺母30123螺纹连接，旋转运动转化为直线运动，带动滑动板30115直线运动；所述左滑动导向轨道30113成“工”字形结构，这样设置左滑动导向轨道30113的一侧端与左滑动座30110的多个滑轮30120相配合在滑动支撑板30119上滑动；同时“工”字形的另一侧端形成了铲盘左滑动件30116的滑动轨道，使得铲盘左滑动件30116在其上滑动；右滑动导向轨道30114与所述左滑动导向轨道30113结构相同且对称设置；这种设置在空间比例上结构紧凑，运作稳定的同时，也提供了足够的铲送组件301的可伸缩长度。
本实施例优选的进一步实施方式，所述自动转运机构3还包括扫码构件302，所述扫码构件302可对其转运的冻存管进行扫码。自动转运机构3在接收中转罐4后，通过暂存架3017对中转罐4进行暂存，再从中转罐4中提取冻存管后，先将冻存管移动至扫码构件302处，对冻存管进行扫码，然后在铲送进深低温储存罐2内；这样扫码对冻存管的信息进行处理，分析及储存，实现高标准自动化。这里进一步公开了扫码构件302包括扫描器3021及扫码镜面3022，可在自动转运机构3内设置一个扫码器安装槽3023，将扫码器3021安装到扫码器安装槽3023内，扫码器安装槽3023上方盖设扫码镜面3022；这样方便扫码。
为了更好的接收中转罐4，及对中转罐4进行转运及与铲送组件301的配合，本实施例优选的进一步实施方式，所述自动转运机构3还包括转运接收箱体303及机械手304；所述转运接收箱体303与所述铲送盒体3011并排设置，所述机械手304设置在所述铲送组件301与所述转运接收箱体303的上方；所述转运接收箱体303接收从所述传递窗101输送进来的中转罐4；所述机械手304可对中转罐4进行抓取；所述铲送盒体3011上端面上开设有铲送接收口30124，所述机械手304可移动到与铲送接收口30124相对应的位置。转运接收箱体303上开设有第一开口3031和第二开口3032，所述第一开口3031与传递窗101贴合对应设置，第二开口3032开设在所述转运接收箱体303的上端面上，可在第二开口3032处设置转运上盖3033；第一开口3031接收中转罐4，传递窗101关闭，第二开口3032处的转运上盖3033开启，机械手304穿过第二开口3032抓取中转罐4放入暂存架3017，铲送组件301将冻存管托盘203铲入到自动转运机构3的铲送盒体3011内，机械手304将暂存架3017上中转罐4内的冻存管抓取；先抓取至扫码构件处，进行扫码，对冻存管的信息进行处理储存；机械手304将冻存管抓取移动至铲送接收口30124处，将冻存管放入到铲送接收口30124下方对应的冻存管托盘203内；铲送组件301再将冻存管托盘203铲送回深低温储存罐2内进行储存。
本实施例优选的进一步实施方式，所述自动转运机构3还包括转运外壳305；所述机械手304包括抓取驱动组件3041、Z轴套3042、Z轴杆3043、Y轴导轨3044、第一X轴导轨3045、第二X轴导轨3046、抓罐机构3047及取管件3048；所述第一X轴导轨3045及第二X轴导轨3046分布固定在所述转运外壳305的两侧端，所述Y轴导向轨3044的两侧端可滑动的设置所述第一X轴导轨3045及第二X轴导轨3046上；所述Z轴套3042竖直设置，且Z轴套3042的中部可滑动的设置在所述Y轴导向轨3044上；所述Z轴杆3043可滑动的设置在所述Z轴套3042内，所述Z轴杆3043的下端设置有Z轴承接件3049，所述抓罐机构3047及取管件3048均分别设置在所Z轴承接件3049上；所述抓罐机构3047可对中转罐4进行抓取，所述取管件3048可对冻存管进行取管；所述抓取驱动组件3041分别对所述Z轴套3042、Y轴导轨3044及Z轴杆3043的运动进行驱动。
Y轴导轨3044的两侧端可沿所述第一X轴导轨3045及第二X轴导轨3046上滑动，实现X轴方向上的运动；Z轴套可在Y轴导轨3044上滑动，实现Y轴方向上的运动；同时，Z轴杆3043可在Z轴套3042内做竖直方向上的上下运动，实现在Z轴方向上的运动；在Z轴杆3043的下端设置Z轴承接件3049，如图13，在Z轴承接件3049的左右两端分别设置抓罐机构3047及取管件3048，所述抓罐机构3047可对中转罐4进行抓取，所述取管件3048可对冻存管进行取管；先利用抓罐机构3047将中转罐4抓取到暂存架3017上，开启中转罐4的罐盖，这里可通过抓罐机构3047对罐盖进行抓取开启，也可以通过其他开盖方式，这里就不再赘述；开启罐盖后，由取管件，将中转罐4内的取管件3048抓取，然后再进行扫码，抓取到冻存管托盘203中等后续动作。
为了尽可能的优化储存环境及深低温储存罐2与自动转运机构3的配合对接；本实施例优选的进一步深低温储存罐2的实施方式，先通过旋转架205的旋转，将需要储存的储存区206的提篮201旋转到相对应的位置，然后再通过提升构件207，将提篮201提取到与储存门204相对应的位置；本发明的深低温储存罐2设计针对在有限的空间内，又能充分的利用储存空间，而且不将整个提篮201提出，只是将需要的冻存管拖盘203进行操作与储存门204相对应提出了进一步的优化实施方式：所述深低温储存罐2内设置有旋转架205、旋转驱动组件208及提升构件207；所述提升构件207嵌套在所述旋转架205内，且所述提升构件207的上部与所述深低温储存罐2的罐体相固定；所述旋转驱动组件208对旋转架205进行驱动，可使得旋转架205在深低温储存罐2内围绕所述提升构件207进行旋转；所述旋转架205被多个分割板分割成多个储存区206，所述储存区206上均开设有提升操作通道209，所述每个提升操作通道209均与所述提升构件207相贯通；所述储存区206内设置有提篮201；所述提篮201外围向外延伸设置一推动接收块2010，且所述推动接收块2010穿过所述提升操作通道209延伸至与所述提升构件207相对应的位置；所述提升构件207可通过对推动接收块2010的作用驱动提篮201沿提升操作通道209在储存区206内做升降运动。 提升构件207嵌套在旋转架205内，大大节省了空间，可节省出大量的空间设置成储存区206；进一步的，所述旋转架205上方中部向下凹设有过渡轴向槽2011，所述过渡轴向槽2011的外围向外延伸设置有多个分隔板2012，且所述过渡轴向槽2011的周向槽壁上开设有多个提升操作通道209；所述提升操作通道209与分隔板2012分成的储存区206一一对应；所述提升构件207包括提升套筒2013、提升驱动电机2014、提升主动轮2015、提升从动轮2016、提升过渡轮2017及提升台2018；所述提升套筒2013设置在所述过渡轴向槽2011内，且可与旋转架205相对旋转；所述提升套筒2013的上部圆周向外延伸有提升过渡板2019，利用提升过渡板2019将提升构件207与深低温储存罐2相固定；本发明的深低温储存罐2优选的实施方式为液氮罐；所述提升驱动电机2014设置在所述深低温储存罐2外部，且所述提升驱动电机2014的电机轴向下延伸依次穿过深低温储存罐2的罐盖及提升过渡板2019设置有提升主动轮2015；所述提升套筒2013外围上端设置有提升过渡轮2017与所述提升主动轮2015啮合连接，这里的提升主动轮2015优选为扇形齿轮与扇形的提升过渡轮2017弧形啮合，为最省力矩的形式设置；所述提升套筒2013外围下端设置有提升从动轮2016，所述提升从动轮2016与所述提升过渡轮2017之间设置有提升传送带2020；所述提升传动带2020上设置有提升台2018，所述提升台2018与所述推动接收块2010相对应。
旋转驱动组件208驱动旋转架205旋转后，即各个储存区206在轴向上旋转，提篮201随着储存区206旋转；因提升操作通道209是开设在过渡轴向槽2011上的，也就是开设在旋转架205上的，每个储存区206的提篮201外围向外延伸设置一推动接收块2010，不仅保证了提篮201在随着储存区206旋转周向上的稳定性，而且，当需要对应的提篮201时，此提篮201停止在于提升构件207相对应的位置，当然提升构件207在周向上始终保持与储存门204相对应的位置；提升驱动电机2014驱动提升主动轮2015，带动提升过渡轮2017，从而带动提升传送带2020在提升过渡轮2017与提升从动轮2016上运动；因保持提升台2018的其实位置始终低于提篮201向提升操作通道209方向延伸的推动接收块2010的位置，所以当提升传送带2020运动时，提升传送带2020上的提升台2018会在运动到推动接收块2010时推动其向上运动，从而带动提篮201沿提升操作通道209做上升运动，直至将需要的冻存管托盘203运动对应到储存门204的位置为止。
本实施例优选的进一步实施方式，所述分隔板2012上设置有储存导向滑行轨道2022，所述提篮201外围也设置有与所述储存导向滑行轨道2022向配合的提篮滑条2023，所述提篮滑条2023在所述储存导向滑行轨道2022上滑动。增强提篮201上升运动的稳定性。
本实施例优选的进一步实施方式，所述提升套筒2013为内部中空的管套；所述过渡轴向槽2011的槽底中心处向提升套筒2013内部延伸设有旋转作用轴2024，旋转作用轴2024上端设置有“十”字接收槽2025；所述旋转驱动组件208包括旋转驱动电机2026和旋转驱动轴2027，所述旋转驱动电机2026固定在所述深低温储存罐2外部，且所述旋转驱动电机2026的电机轴与所述旋转驱动轴2027同轴连接，所述旋转驱动轴2026下端设置有“十”字卡接件2028，且旋转驱动轴2027的卡接件2028卡合在接收槽2025内。
本实施例优选的进一步实施方式，所述提篮201成扇形，且所述提篮201内的两侧设置有多个支撑条2029，每两条在同一水平面上的支撑条2029形成所述的托盘支撑件202。
本实施例优选的进一步实施方式，所述冻存管托盘203为与提篮201相契合的扇形，且所述冻存管托盘203上设置有多个存管槽2030，所述存管槽2030的槽底为开发式槽底。这里所述的开放式槽底，如图6所示，在槽底开设开放孔，在冻存管存放时，冻存管可插入到其中，更加稳定。
本实施例优选的进一步实施方式，还包括检修门5、供氮系统及除湿系统，所述检修门5设置在所述储存库箱体1上，可通过检修门5打开储存库箱体1，对其内部进行检修；所述供氮系统可对储存库箱体1内进行供氮，也可对自动转运机构内供氮；所述除湿系统可对储存库箱体1进行除湿，除湿系统包括多个除湿机7。维护保养方便，万一其有故障可快速更换。
 
实施例2
本实施例提供了一种生物样本储存库的储存方法，R步骤,将存有冻存管的中转罐直接通过储存库箱体的传递窗放入到储存库中；S步骤,储存库中的自动转运机构将接收到的中转罐内的冻存管自动转送到所述深低温储存罐内。这种储存方式摒弃了现有技术中人工储存带来的对冻存管环境破坏的风险，而且方便，高效，准确。
本实施例优选的进一步实施方式，S1步骤,自动转运机构的机械手将储存库接收的中转罐抓取到设定的暂存架上；
S2步骤，在进行S1步骤的同时或在上述R步骤之后，自动转运机构会沿着指定线路运动到相对应的深低温储存罐处；
S3步骤，深低温储存罐的储存门打开，自动转运机构的铲送组件对深低温储存罐内的冻存管托盘铲入到自动转运机构相对应的平台上；
S4步骤，机械手抓取暂存架上中转罐内的冻存管放置到冻存管托盘上；
S5步骤，铲送组件再将冻存管拖盘输送回深低温储存罐内。
利用自动转运机构在多个深低温储存罐之间可以移动行走的方式，替代了现有技术中人工在多个深低温储存罐中寻找对接的过程，而且使得深低温储存罐更方便分类设置，大大提高了储存效率。利用铲送的方式进行自动转运机构与深低温储存罐之间的对接，大大提高了将冻存管存入深低温储存罐的效率。
本实施例优选的进一步实施方式，在所述S4步骤进行时，机械手先从暂存架上将冻存管抓取至扫码构件上方对冻存管上的二维码进行扫码，设置的控制系统，对扫码结果进行处理及储存，之后再将冻存管抓取至冻存管托盘上。
本实施例优选的进一步实施方式，T步骤,在所述S3步骤进行之前，深低温储存罐内的相对应的提篮移动到与储存门相对应的位置；
所述T步骤分为：
T1步骤，深低温储存罐的旋转驱动组件驱动旋转架旋转，从而带动旋转架上的提篮在周向上运动到深低温储存罐的储存门相对应的位置处；
T2步骤，提升构件将提篮提升，使其提篮上的冻存管托盘提升至铲送组件可穿过储存门对其铲送的位置。
本实施例优选的进一步实施方式，还包括G步骤：将储存库箱体直接通过设有集装箱的运输车直接运输。一个集装箱即可对其运输，安装方便现场适应性、扩充性强。
 
以上实施例的先后顺序仅为便于描述，不代表实施例的优劣。
最后应说明的是：以上实施例仅用以说明本发明的技术方案，而非对其限制；尽管参照前述实施例对本发明进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本发明各实施例技术方案的精神和范围。

Claims (20)

  1. [根据细则26改正20.02.2019]
    一种生物样本储存库，其特征在于，包括储存库箱体、多个深低温储存罐及自动转运机构；所述至少一个深低温储存罐及自动转运机构均设置在所述储存库箱体内；
    所述储存库箱体上开设有传递窗，所述自动转运机构可接收从外部通过传递窗传送来的存有冻存管的中转罐；且所述自动转运机构可将接收到的中转罐内的冻存管转送到所述深低温储存罐内。
  2. [根据细则26改正20.02.2019]
    根据权利要求1所述的生物样本储存库，其特征在于，
    所述深低温储存罐内设置有可移动位置的提篮，所述提篮内设置有多个托盘支撑件，所述托盘支撑件上撑托有冻存管托盘；所述深低温储存罐设置有储存门，每个所述托盘支撑件均可随着提篮的移动，从而移动到与所述储存门相对应的位置；
    所述自动转运机构包括铲送组件，所述铲送组件可穿过储存门将提篮内的冻存管托盘铲起接收或可将接收的冻存管托盘铲送回提篮内。
  3. [根据细则26改正20.02.2019]
    根据权利要求2所述的生物样本储存库，其特征在于，所述铲送组件包括铲送盒体、铲送第一驱动件、铲送第二驱动件、铲送滑动底座、滑动导向板、铲盘组件及暂存架；
    所述铲送盒体上开设有铲送输送口，且所述铲送输送口可与所述深低温储存罐的储存门相对应；
    所述暂存架及所述铲送滑动底座均设置在所述铲送盒体内，所述滑动导向板可滑动的设置在所述铲送滑动底座上，所述铲盘组件可滑动的设置在所述滑动导向板上；
    所述暂存架可对中转罐进行暂存；
    所述铲送盒体上开设有铲送通氮孔，所述铲送通氮孔与供氮系统连通；
    所述铲送第一驱动件对所述滑动导向板的滑动进行驱动，所述铲送第二驱动件对铲盘组件的滑动进行驱动。
  4. [根据细则26改正20.02.2019]
    根据权利要求3所述的生物样本储存库，其特征在于，所述铲送滑动底座包括左滑动座、右滑动座及底座框架，所述左滑动座与右滑动座分别设置在所述底座框架的左右两侧；
    所述滑动导向板包括左滑动导向轨道、右滑动导向轨道及滑动板；所述左滑动导向轨道及右滑动导向轨道分别设置在所述滑动板的左右两侧端；
    所述铲盘组件包括铲盘左滑动件、铲盘右滑动件及铲盘；所述铲盘左滑动件及铲盘右滑动件设置在所述铲盘的左右两侧；
    所述左滑动导向轨道的外侧在所述左滑动座上滑动，所述右滑动导向轨道的外侧在所述右滑动座上滑动，所述铲盘左滑动件在所述左滑动导向轨道的内侧上滑动，所述铲盘右滑动件在所述右滑动导向轨道内侧上滑动。
  5. [根据细则26改正20.02.2019]
    根据权利要求4所述的生物样本储存库，其特征在于，
    所述左滑动座包括滑动支撑板和多个滑轮，所述多个滑轮成一排设置在所述滑动支撑板上；所述右滑动座与所述左滑动座结构相同且对称设置；
    所述左滑动导向轨道成“工”字形，所述右滑动导向轨道与所述左滑动导向轨道结构相同且对称设置；
    所述铲送第一驱动件包括铲送驱动电机及丝杠，所述滑动板下端面上设置有丝杠螺母，所述丝杠螺母与丝杠螺纹连接，所述铲送驱动电机的电机轴与所述丝杠连接。
  6. [根据细则26改正20.02.2019]　
    根据权利要求1所述的生物样本储存库，其特征在于，所述自动转运机构还包括扫码构件，所述扫码构件可对其转运的冻存管进行扫码。
  7. [根据细则26改正20.02.2019]
    根据权利要求3、4或5所述的生物样本储存库，其特征在于，所述自动转运机构还包括转运接收箱体及机械手；
    所述转运接收箱体与所述铲送盒体并排设置，所述机械手设置在所述铲送组件与所述转运接收箱体的上方；
    所述转运接收箱体接收从所述传递窗输送进来的中转罐；所述机械手可对中转罐进行抓取；
    所述铲送盒体上端面上开设有铲送接收口，所述机械手可移动到与铲送接收口相对应的位置。
  8. [根据细则26改正20.02.2019]
    根据权利要求7所述的生物样本储存库，其特征在于，所述自动转运机构还包括转运外壳；所述机械手包括抓取驱动组件、Z轴套、Z轴杆、Y轴导轨、第一X轴导轨、第二X轴导轨、抓罐机构及取管件；
    所述第一X轴导轨及第二X轴导轨分布固定在所述转运外壳的两侧端，所述Y轴导向轨的两侧端可滑动的设置所述第一X轴导轨及第二X轴导轨上；所述Z轴套竖直设置，且Z轴套的中部可滑动的设置在所述Y轴导向轨上；
    所述Z轴杆可滑动的设置在所述Z轴套内，所述Z轴杆的下端设置有Z轴承接件，所述抓罐机构及取管件均分别设置在所Z轴承接件上；
    所述抓罐机构可对中转罐进行抓取，所述取管件可对冻存管进行取管；
    所述抓取驱动组件分别对所述Z轴套、Y轴导轨及Z轴杆的运动进行驱动。
  9. [根据细则26改正20.02.2019]
    根据权利要求1、2、3、4、5、6或8所述的生物样本储存库，其特征在于，所述深低温储存罐内设置有旋转架、旋转驱动组件及提升构件；
    所述提升构件嵌套在所述旋转架内，且所述提升构件的上部与所述深低温储存罐的罐体相固定；所述旋转驱动组件对旋转架进行驱动，可使得旋转架在深低温储存罐内围绕所述提升构件进行旋转；
    所述旋转架被多个分割板分割成多个储存区，所述储存区上均开设有提升操作通道，所述每个提升操作通道均与所述提升构件相贯通；
    所述储存区内设置有提篮；所述提篮外围向外延伸设置一推动接收块，且所述推动接收块穿过所述提升操作通道延伸至与所述提升构件相对应的位置；
    所述提升构件可通过对推动接收块的作用驱动提篮沿提升操作通道在储存区内做升降运动。
  10. [根据细则26改正20.02.2019]
    根据权利要求9所述的生物样本储存库，其特征在于，
    所述旋转架上方中部向下凹设有过渡轴向槽，所述过渡轴向槽的外围向外延伸设置有多个分隔板，且所述过渡轴向槽的周向槽壁上开设有多个提升操作通道；所述提升操作通道与分隔板分成的储存区一一对应；
    所述提升构件包括提升套筒、提升驱动电机、提升主动轮、提升从动轮、提升过渡轮及提升台；
    所述提升套筒设置在所述过渡轴向槽内，且可与旋转架相对旋转；所述提升套筒的上部圆周向外延伸有提升过渡板，所述提升驱动电机设置在所述深低温储存罐外部，且所述提升驱动电机的电机轴向下延伸依次穿过深低温储存罐的罐盖及提升过渡板设置有提升主动轮；
    所述提升套筒外围上端设置有提升过渡轮与所述提升主动轮啮合连接，所述提升套筒外围下端设置有提升从动轮，所述提升从动轮与所述提升过渡轮之间设置有提升传送带；所述提升传动带上设置有提升台，所述提升台与所述推动接收块相对应。
  11. [根据细则26改正20.02.2019]　
    根据权利要求10所述的生物样本储存库，其特征在于，所述分隔板上设置有储存导向滑行轨道，所述提篮外围也设置有与所述储存导向滑行轨道向配合的提篮滑条，所述提篮滑条在所述储存导向滑行轨道上滑动。
  12. [根据细则26改正20.02.2019]
    根据权利要求10所述的生物样本储存库，其特征在于，
    所述提升套筒为内部中空的管套；
    所述过渡轴向槽的槽底中心处向提升套筒内部延伸设有旋转作用轴，旋转作用轴上端设置有“十”字接收槽；
    所述旋转驱动组件包括旋转驱动电机和旋转驱动轴，所述旋转驱动电机固定在所述深低温储存罐外部，且所述旋转驱动电机的电机轴与所述旋转驱动轴同轴连接，所述旋转驱动轴下端设置有“十”字卡接件，且旋转驱动轴的卡接件卡合在接收槽内。
  13. [根据细则26改正20.02.2019]　
    根据权利要求1、2、3、4、5、6、8、10、11或12所述的生物样本储存库，其特征在于，所述提篮成扇形，且所述提篮内的两侧设置有多个支撑条，每两条在同一水平面上的支撑条形成所述的托盘支撑件。
  14. [根据细则26改正20.02.2019]　
    根据权利要求13所述的生物样本储存库，其特征在于，所述冻存管托盘为与提篮相契合的扇形，且所述冻存管托盘上设置有多个存管槽，所述存管槽的槽底为开发式槽底。
  15. [根据细则26改正20.02.2019]
    根据权利要求1、2、3、4、5、6、8、10、11、12或14所述的生物样本储存库，其特征在于，
    还包括检修门、供氮系统及除湿系统，所述检修门设置在所述储存库箱体上，可通过检修门打开储存库箱体，对其内部进行检修；
    所述供氮系统可对储存库箱体内进行供氮，也可对自动转运机构内供氮；
    所述除湿系统可对储存库箱体进行除湿。
  16. [根据细则26改正20.02.2019]
    一种生物样本储存库的储存方法，其特征在于，
    R步骤,将存有冻存管的中转罐直接通过储存库箱体的传递窗放入到储存库中；
    S步骤,储存库中的自动转运机构将接收到的中转罐内的冻存管自动转送到所述深低温储存罐内。
  17. [根据细则26改正20.02.2019]
    根据权利要求16所述的生物样本储存库的储存方法，其特征在于，
    S1步骤,自动转运机构的机械手将储存库接收的中转罐抓取到设定的暂存架上；
    S2步骤，在进行S1步骤的同时或在上述R步骤之后，自动转运机构会沿着指定线路运动到相对应的深低温储存罐处；
    S3步骤，深低温储存罐的储存门打开，自动转运机构的铲送组件对深低温储存罐内的冻存管托盘铲入到自动转运机构相对应的平台上；
    S4步骤，机械手抓取暂存架上中转罐内的冻存管放置到冻存管托盘上；
    S5步骤，铲送组件再将冻存管拖盘输送回深低温储存罐内。
  18. [根据细则26改正20.02.2019]
    根据权利要求17所述的生物样本储存库的储存方法，其特征在于，
     在所述S4步骤进行时，机械手先从暂存架上将冻存管抓取至扫码构件上方对冻存管上的二维码进行扫码，设置的控制系统，对扫码结果进行处理及储存，之后再将冻存管抓取至冻存管托盘上。
  19. [根据细则26改正20.02.2019]
    根据权利要求17或18所述的生物样本储存库的储存方法，其特征在于，
    T步骤,在所述S3步骤进行之前，深低温储存罐内的相对应的提篮移动到与储存门相对应的位置；
    所述T步骤分为：
    T1步骤，深低温储存罐的旋转驱动组件驱动旋转架旋转，从而带动旋转架上的提篮在周向上运动到深低温储存罐的储存门相对应的位置处；
    T2步骤，提升构件将提篮提升，使其提篮上的冻存管托盘提升至铲送组件可穿过储存门对其铲送的位置。
  20. [根据细则26改正20.02.2019]　
    根据权利要求16、17或18所述的生物样本储存库的储存方法，其特征在于，还包括G步骤：将储存库箱体直接通过设有集装箱的运输车直接运输。
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CN115265082A (zh) * 2022-06-24 2022-11-01 青岛海尔生物医疗科技有限公司 用于液氮罐挑管的装置
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CN116555030A (zh) * 2023-06-12 2023-08-08 北京康泰联和国际生物科技有限公司 一种基于脐带间充质干细胞培养的存放设备
CN116555030B (zh) * 2023-06-12 2023-12-08 北京康泰联和国际生物科技有限公司 一种基于脐带间充质干细胞培养的存放设备

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