WO2019220389A1 - Tablets containing polyphosphates - Google Patents

Tablets containing polyphosphates Download PDF

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Publication number
WO2019220389A1
WO2019220389A1 PCT/IB2019/054065 IB2019054065W WO2019220389A1 WO 2019220389 A1 WO2019220389 A1 WO 2019220389A1 IB 2019054065 W IB2019054065 W IB 2019054065W WO 2019220389 A1 WO2019220389 A1 WO 2019220389A1
Authority
WO
WIPO (PCT)
Prior art keywords
polyphosphates
tablets
weight
polyphosphate
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2019/054065
Other languages
English (en)
French (fr)
Inventor
Joaquin LIZANO
Rene HOEKSEMA
Gladys BROUNS
Andrea Sarrica
Alessandro Bottini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Perfetti Van Melle SpA
Original Assignee
Perfetti Van Melle SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perfetti Van Melle SpA filed Critical Perfetti Van Melle SpA
Priority to CA3097796A priority Critical patent/CA3097796A1/en
Priority to US17/055,192 priority patent/US20210220239A1/en
Priority to AU2019268582A priority patent/AU2019268582A1/en
Priority to BR112020023365-0A priority patent/BR112020023365A2/pt
Priority to CN201980031782.6A priority patent/CN112105269A/zh
Priority to EP19730954.5A priority patent/EP3793374A1/en
Priority to JP2020564194A priority patent/JP2021523203A/ja
Priority to MX2020012194A priority patent/MX2020012194A/es
Publication of WO2019220389A1 publication Critical patent/WO2019220389A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/362—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/65—Characterized by the composition of the particulate/core
    • A61K2800/651—The particulate/core comprising inorganic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration

Definitions

  • the invention relates to confectionery products, in particular tablets, containing at least one micronised polyphosphate.
  • compositions containing polyphosphates for the removal of tooth stains were described in US6685916, which suggests the use of one of the following polyphosphates together with other substances, including peroxide compounds and anionic surfactants: sodium tripolyphosphate, potassium tripolyphosphate, sodium pyrophosphate, sodium trimetaphosphate and sodium hexametaphosphate.
  • US6685916 deals with the problem of the unpleasant aftertaste typical of polyphosphates by proposing a solution based on the selection of specific doses of said polyphosphates.
  • Polyphosphates are also known to cause an accentuated residual roughness in the products containing them.
  • US3054656 which refers in particular to the production of a pure sodium tripolyphosphate intended for use in the detergent industry, expressly mentions the question of roughness, which can be eliminated by processing sodium tripolyphosphate at very high temperatures under particular humidity conditions.
  • EP 1 227 789 describes confectionery products comprising polyphosphates, whose particle size is not stated, unlike that of the other ingredients, in particular silicates, used as abrasives in sizes ranging between 0.1 and 30 microns. Polyphosphates are only used in toothpastes, not in the tablets.
  • US 2003/008062 describes chewable compositions for dental hygiene, in particular chewing gums, containing various ingredients including micronised polyphosphates inserted in a rough, crunchy matrix, comprising a large particulate able to give the desired rough, crunchy texture.
  • the invention therefore relates to a tablet comprising one or more polyphosphates in micronised form and one or more polyols.
  • the tablets according to the invention obtained by direct compression, have a smooth, not rough or crunchy texture, and dissolve in the oral cavity without chewing within a few minutes.
  • At least 90% by weight of the polyphosphates used to prepare the confectionery products, especially tablets, have a particle size of less than 150 pm.
  • a micronised polyphosphate is preferably used wherein over 90% by weight of particles have a size of less than 150 pm, preferably over 90% by weight of the particles have a size of less than 106 pm, and more preferably over 80% by weight of the particles have a size of less than 53 pm.
  • Micronised polyphosphates are available on the market or can be obtained by subjecting commercial polyphosphates to conventional methods of micronisation, until the above-mentioned specifications are reached.
  • the tablet according to the invention does not contain sugar, but can contain any polyol, preferably sorbitol, xylitol and isomalt, either alone or mixed. Sorbitol is preferred, in percentages by weight ranging from 80 to 98%. It can also include flavourings, sweeteners and compression auxiliaries (lubricants and the like).
  • the polyphosphate contained in the tablet is selected from sodium tripolyphosphate, potassium tripolyphosphate, sodium pyrophosphate, sodium trimetaphosphate and sodium hexametaphosphate.
  • the tablet can also contain other active ingredients that do not interact with polyphosphates, such as vitamins.
  • the tablet preferably does not contain mineral salts.
  • the products according to example 1 and example 2 were compared for roughness by a panel of thirteen expert tasters, according to the Quantitative Descriptive Analysis technique.
  • the tasters blind-tasted one tablet for each example, 1 and 2, at separate times. They were required to suck the tablets for 3 minutes and score their roughness on a V AS scale from 0 (smooth) to 100 (rough) immediately, and after every minute’s consumption.
  • the scores are set out below:
  • the products according to the invention are therefore able to reduce the formation of tooth stains. None of the participants dropped out of the test, and all reported that the palatability of the tablets was acceptable.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Confectionery (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
PCT/IB2019/054065 2018-05-16 2019-05-16 Tablets containing polyphosphates Ceased WO2019220389A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CA3097796A CA3097796A1 (en) 2018-05-16 2019-05-16 Tablets containing polyphosphates
US17/055,192 US20210220239A1 (en) 2018-05-16 2019-05-16 Tablets containing polyphosphates
AU2019268582A AU2019268582A1 (en) 2018-05-16 2019-05-16 Tablets containing polyphosphates
BR112020023365-0A BR112020023365A2 (pt) 2018-05-16 2019-05-16 pastilhas contendo polifosfatos
CN201980031782.6A CN112105269A (zh) 2018-05-16 2019-05-16 含有多磷酸盐的片剂
EP19730954.5A EP3793374A1 (en) 2018-05-16 2019-05-16 Tablets containing polyphosphates
JP2020564194A JP2021523203A (ja) 2018-05-16 2019-05-16 ポリリン酸塩を含有するタブレット
MX2020012194A MX2020012194A (es) 2018-05-16 2019-05-16 Tabletas que contienen polifosfatos.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102018000005426 2018-05-16
IT201800005426A IT201800005426A1 (it) 2018-05-16 2018-05-16 Prodotto di confetteria contenente polifosfati

Publications (1)

Publication Number Publication Date
WO2019220389A1 true WO2019220389A1 (en) 2019-11-21

Family

ID=63080360

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2019/054065 Ceased WO2019220389A1 (en) 2018-05-16 2019-05-16 Tablets containing polyphosphates

Country Status (10)

Country Link
US (1) US20210220239A1 (https=)
EP (1) EP3793374A1 (https=)
JP (1) JP2021523203A (https=)
CN (1) CN112105269A (https=)
AU (1) AU2019268582A1 (https=)
BR (1) BR112020023365A2 (https=)
CA (1) CA3097796A1 (https=)
IT (1) IT201800005426A1 (https=)
MX (1) MX2020012194A (https=)
WO (1) WO2019220389A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250176585A1 (en) * 2022-03-03 2025-06-05 Wm. Wrigley Jr. Company Deep cleaning chewing gum

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0409774A1 (fr) * 1989-07-17 1991-01-23 Jean-Paul Atdjian Composition retardatrice de prise pour liants hydrauliques, et procédé de sa préparation
WO1997012607A1 (en) * 1995-10-03 1997-04-10 Church & Dwight Company, Inc. Chewing gum product with plaque-inhibiting benefits
US6416744B1 (en) * 2001-06-21 2002-07-09 Colgate Palmolive Company Tooth whitening chewing gum
EP1227789A1 (en) * 1999-11-12 2002-08-07 The Procter & Gamble Company Improved dual phase stannous oral compositions
US20030003219A1 (en) * 2001-05-15 2003-01-02 The Procter & Gamble Company Confectionery compositions
US20030008062A1 (en) * 2001-05-15 2003-01-09 Day Trevor Neil Confectionery compositions
US6685916B1 (en) * 2002-10-31 2004-02-03 Cadbury Adams Usa Llc Compositions for removing stains from dental surfaces, and methods of making and using the same

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806340A (en) * 1985-09-13 1989-02-21 Colgate-Palmolive Company Anticalculus oral composition
IN168400B (https=) * 1987-01-30 1991-03-23 Colgate Palmolive Co
US5180576A (en) * 1991-08-30 1993-01-19 Church & Dwight Co., Inc. Anticalculus dentifrices
JPH10182389A (ja) * 1996-12-27 1998-07-07 Lion Corp 歯磨組成物
JP4627999B2 (ja) * 2004-02-27 2011-02-09 太陽化学株式会社 坑酸化剤
US20060024245A1 (en) * 2004-07-29 2006-02-02 Cadbury Adams, Llc. Tooth whitening compositions and delivery systems therefor
ES2442253T3 (es) * 2007-02-23 2014-02-10 The Procter & Gamble Company Composiciones orales de polifosfato
US9289369B2 (en) * 2010-12-20 2016-03-22 Colgate-Palmolive Company Non-aqueous oral care composition containing dental occlusion actives
WO2012087279A1 (en) * 2010-12-20 2012-06-28 Colgate-Palmolive Company Gelatin encapsulated oral care composition containing dental occlusion actives, hydrophobic viscosity modifier and oil carrier
US9320690B2 (en) * 2010-12-20 2016-04-26 Colgate-Palmolive Company Gelatin encapsulated oral care composition containing hydrophilic active, hydrophobic structuring agent and oil carrier
JP2018502099A (ja) * 2014-12-24 2018-01-25 ザ ユニヴァーシティー オブ メルボルン 石灰化フルオリド組成物
CN108348439A (zh) * 2015-10-26 2018-07-31 巴斯夫欧洲公司 包含羟基磷灰石结合蛋白质的口腔护理产品和方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0409774A1 (fr) * 1989-07-17 1991-01-23 Jean-Paul Atdjian Composition retardatrice de prise pour liants hydrauliques, et procédé de sa préparation
WO1997012607A1 (en) * 1995-10-03 1997-04-10 Church & Dwight Company, Inc. Chewing gum product with plaque-inhibiting benefits
EP1227789A1 (en) * 1999-11-12 2002-08-07 The Procter & Gamble Company Improved dual phase stannous oral compositions
US20030003219A1 (en) * 2001-05-15 2003-01-02 The Procter & Gamble Company Confectionery compositions
US20030008062A1 (en) * 2001-05-15 2003-01-09 Day Trevor Neil Confectionery compositions
US6416744B1 (en) * 2001-06-21 2002-07-09 Colgate Palmolive Company Tooth whitening chewing gum
US6685916B1 (en) * 2002-10-31 2004-02-03 Cadbury Adams Usa Llc Compositions for removing stains from dental surfaces, and methods of making and using the same

Also Published As

Publication number Publication date
US20210220239A1 (en) 2021-07-22
IT201800005426A1 (it) 2019-11-16
CN112105269A (zh) 2020-12-18
MX2020012194A (es) 2021-01-29
BR112020023365A2 (pt) 2021-02-09
CA3097796A1 (en) 2019-11-21
JP2021523203A (ja) 2021-09-02
EP3793374A1 (en) 2021-03-24
AU2019268582A1 (en) 2020-11-26

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