WO2018232739A1 - 一种用于止咳化痰的药丸及其制备方法 - Google Patents

一种用于止咳化痰的药丸及其制备方法 Download PDF

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WO2018232739A1
WO2018232739A1 PCT/CN2017/089780 CN2017089780W WO2018232739A1 WO 2018232739 A1 WO2018232739 A1 WO 2018232739A1 CN 2017089780 W CN2017089780 W CN 2017089780W WO 2018232739 A1 WO2018232739 A1 WO 2018232739A1
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parts
pill
honey
pellet
phlegm
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PCT/CN2017/089780
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English (en)
French (fr)
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郭建钊
江红格
申涛
郭宇鹏
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禹州市天源生物科技有限公司
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Priority to PCT/CN2017/089780 priority Critical patent/WO2018232739A1/zh
Publication of WO2018232739A1 publication Critical patent/WO2018232739A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964—Anemarrhena
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966—Fritillaria, e.g. checker lily or mission bells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Definitions

  • the invention relates to a medicine used in the field of disease treatment, in particular to a medicine pill for relieving cough and phlegm and a preparation method thereof.
  • Hot coughing is a sinister airway, lungs are lost, and the patients are caused by phlegm and heat. If the symptoms are unresolved, they can see both symptoms.
  • the clinical manifestations are cough, phlegm and yellow thick, vomiting, sputum, sputum, sputum, sputum, dull throat, red tongue, thin yellow or greasy fur, slippery pulse; Western medicine diagnosis of bronchitis, more cold infection or exposure history
  • the lung auscultation can smell dry and wet rales. The patient's coughing and screaming is not only uncomfortable, but also seriously affects the lives of people around him.
  • the present invention provides a pill for relieving cough and removing phlegm and preparation method thereof By taking the pill according to the course of treatment, it can quickly and effectively relieve the symptoms, cure the patient, and has the effect of preventing recurrence.
  • a pill for relieving cough and phlegm which is prepared by mixing a main agent and a sub-agent, wherein the main agent is made up of the following components by weight: Schisandra 4-6 4-6 parts of medlar, 4-6 parts of licorice, 25-35 parts of Fritillaria, 25-35 parts of Zhimu, 15-25 parts of Astragalus, 10-20 parts of orange red, 15-25 parts of mulberry white 25-35 parts of melon, 25-35 parts of raw gypsum, 15-25 parts of fried medlar, 5-15 parts of red peony; the secondary agent is made up of the following components by weight: 260-300 parts of honey.
  • the preparation method of the above-mentioned pill for relieving cough and removing phlegm includes the following steps:
  • the medicinal material is ground, according to the above component requirements, the medicinal material of the main medicament is selected and weighed, and then ground into a fine powder with a fineness of 80-120 mesh, and mixed into a sterilizing pot for mixing;
  • the pellets are cut into strips by hand or pelletized for further cutting into pellets, and the thickness of the pellets is determined by the size of the pellets;
  • the lubricant is prepared by heat fusion of sesame oil and yellow wax by 3:1.
  • Zhimu Sexual taste bitter, cold, return to the lungs, stomach, kidney, with heat and purging fire, nourishing yin and moistening effect, attending fever, polydipsia, lung heat dry cough, bone steaming hot flash, internal heat, thirst, intestine Dry constipation embolism.
  • Astragalus roots into the medicine, bitter taste, cold, with heat and dampness, purging fire detoxification, hemostasis, and fetus. Indications of warm disease, upper respiratory tract infection, lung heat cough, damp heat yellow biliary, pneumonia, dysentery, hemoptysis, red eyes, fetal dysphoria, high blood pressure, carbuncles and hemorrhoids embolism.
  • Raw gypsum Sexual taste, dry, slightly cold, return to the lungs, stomach. It has clearing heat and purging fire, in addition to annoying thirst, astringent muscle effect, attending stroke cold and heat, heart under the gas and panting, dry mouth Jiao Jiao, can not breathe, abdominal pain, puerperal gold sore embolism.
  • Mulberry white skin sweet and cold.
  • this product is antipyretic phlegm, for acute bronchitis, pneumonia, emphysema, pulmonary edema and other cough caused by effective, and significant diuretic It can bring out more chloride, which is effective for urinary dysfunction, swollen face, athlete's foot swelling and nephritis edema.
  • Schisandra Sour taste, sweet, warm. Return to the lungs, heart, kidney, with astringent solid, Yiqi Shengjin, Bushen Ningxin effect. Indications for a long time, fatigue, dreams slippery essence, enuresis and frequent urination, long-term diarrhea, spontaneous sweating, night sweats, Tianjin wounds thirst, short qi deficiency, internal heat and thirst, palpitations, insomnia and other symptoms.
  • Orange red sweet, bitter, warm, lung, spleen, have a wide range of qi, dry and phlegm, attending cough, food, injury, vomiting and nausea.
  • Tamping Sexual taste is bitter, cold. Return to the spleen, stomach, large intestine. It has the effect of breaking the gas and removing the product, eliminating the phlegm and eliminating phlegm; the main cause of food stagnation is stagnation, qi stagnation, chest and abdomen, fullness and pain, and dysentery after dysentery.
  • Red peony spicy, warm, non-toxic.
  • attending heart and kidney qi deficiency deliberately not defensive, urinary leach or can not help, remnant white turbid, chest threat counter full of thirst embolism.
  • Licorice sweet, flat, heart, lung, spleen, stomach. It has the functions of replenishing spleen and replenishing qi, moistening the lungs and relieving cough, relieving pain and relieving pain, and alleviating medicinal properties
  • the invention selects a plurality of traditional Chinese medicines which have curative effect on relieving cough and phlegm, and the mother-in-law is slightly cold, clearing heat and moistening dryness, relieving cough and relieving cough, knowing mother and cold, clearing lungs and moistening dryness, and being a common medicine.
  • a total of adjuvants Licorice moistens the lungs and relieves cough, reconciles the medicinal properties and acts as an adjuvant. All kinds of medicines play a clear lung and moistening dryness, and have the effect of relieving phlegm and relieving cough.
  • the honey is treated in several steps to kill microorganisms contained in the honey for sterilization, and concentrated by heating to increase the viscosity while removing impurities such as foam.
  • the production process of the invention adopts the original raw Chinese medicine raw materials, has no side effects on the human body, and the cough pills are more targeted for the chronic symptoms of coughing, convenient to take, and low in cost, and proved by clinical experiments that the medicine of the present invention is suitable for dry heat Pulmonary cough for a long time, the symptoms of Qi Sheng Qi have a better therapeutic effect.
  • a pill for relieving cough and phlegm which is prepared by mixing a main agent and a sub-agent, wherein the main agent is made up of the following components by weight: 4 parts of Schisandra, 4 parts of medlar, 4 parts of licorice, Fritillaria 25 parts, 25 parts of Zhimu, 15 parts of Astragalus, 10 parts of orange, 15 parts of mulberry, 25 parts of melon, 25 parts of raw gypsum, 15 parts of fried hazelnut, 5 parts of red peony; Made of ingredients: 260 parts of honey.
  • the above preparation method for cough and phlegm pills comprises the following steps:
  • the medicinal material is ground, according to the above component requirements, the medicinal material of the main medicament is selected and weighed, and then ground into a fine powder with a fineness of 80 mesh, and mixed into a sterilizing pot for mixing;
  • the pellets are cut into strips by hand or pelletized for further cutting into pellets, and the thickness of the pellets is determined by the size of the pellets;
  • the invention relates to a pill for relieving cough and phlegm, which is prepared by mixing a main medicament and a secondary medicament, wherein the main medicament is made by the following components by weight: 6 parts of Schisandra, 6 parts of medlar, 6 parts of licorice, Fritillaria 35 parts, 35 parts of Zhimu, 25 parts of Astragalus, 20 parts of orange, 25 parts of mulberry, 35 parts of melon, 35 parts of raw gypsum, 25 parts of fried hazelnut, 15 parts of red peony; Made of ingredients: 300 parts of honey.
  • the above preparation method for cough and phlegm pills comprises the following steps:
  • the medicinal material is ground, according to the above component requirements, the medicinal material of the main medicament is selected and weighed, and then ground into a fine powder with a fineness of 120 mesh, which is mixed into a sterilizing pot and mixed for use;
  • the pellets are cut into strips by hand or pelletized for further cutting into pellets, and the thickness of the pellets is determined by the size of the pellets;
  • a pill for relieving cough and phlegm comprising a mixture of a main agent and a sub-agent, wherein the main agent is made up of the following components by weight: 5 parts of Schisandra, 5 parts of medlar, 5 parts of licorice, Fritillaria 30 parts, 30 parts of Zhimu, 20 parts of Astragalus, 15 parts of orange, 20 parts of mulberry, 30 parts of melon, 30 parts of raw gypsum, 20 parts of fried medlar, 10 parts of red peony; Made of ingredients: 280 parts of honey.
  • the above preparation method for cough and phlegm pills comprises the following steps:
  • the medicinal material is ground, according to the above component requirements, the medicinal material of the main medicament is selected and weighed, and then ground into a fine powder with a fineness of 100 mesh, which is mixed into a sterilizing pot and mixed for use;
  • the pellets are cut into strips by hand or pelletized for further cutting into pellets, and the thickness of the pellets is determined by the size of the pellets;

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Abstract

一种用于止咳化痰的药丸，由中药和辅料混合而成。所述中药由以下原料制成：五味子，枳实，甘草，川贝母，知母，黄芩，橘红，桑白皮，瓜蒌，生石膏，炒栀子和赤茯苓。所述辅料由蜂蜜制成。所述药丸用原生态的中药原料制成，对人体无副作用。该药丸用于治疗长时间咳嗽引起的慢性症状，具有针对性强，服用方便，成本低廉，快速缓解症状，治愈患者，防止复发的功效。

Description

一种用于止咳化痰的药丸及其制备方法 技术领域
本发明涉及疾病治疗领域用到的药物，具体涉及一种用于止咳化痰的药丸及其制备方法。
背景技术
痰热咳嗽为邪犯气道、肺失宣肃而致痰热蕴肺证患者，若表邪未解可兼见表症。临床表现为咳嗽、痰黄稠、咯吐不爽，鼻塞流浊涕，咽痛声哑，舌质红，苔薄黄或腻，脉滑数；西医诊断为支气管炎，多有受凉感染或接触史，肺部听诊可闻及干、湿性罗音。患者不停的咳嗽发出异声，不仅自身难受异常，而且也严重影响周围人的生活。
发明内容
为了消除因燥热蕴肺所致的咳嗽、痰黄而黏不易咳出、胸闷气促、久咳不止和声哑喉痛等症状，本发明提供一种用于止咳化痰的药丸及其制备方法，按照疗程服用该药丸，可以快速有效地缓解症状，治愈患者，而且具有防止复发的功效。
为了实现上述目的，本发明采用如下技术方案：一种用于止咳化痰的药丸，由主药剂和副药剂混合而成，其中，主药剂按重量百分比由以下组分制成：五味子4-6份，枳实4-6份，甘草4-6份，川贝母25-35份，知母25-35份，黄岑15-25份，橘红10-20份，桑白皮15-25份，瓜蒌25-35份，生石膏25-35份，炒栀子15-25份，赤苓5-15份；副药剂按重量百分比由以下组分制成：蜂蜜260-300份。
上述用于止咳化痰的药丸的制备方法，包括如下步骤：
(1)药材磨粉，按照上述组分要求选用并称量制取主药剂的药材，然后磨成细度为80-120目的细粉，装入消毒盆中混匀备用；
(2)熬炼蜂蜜，按照上述要求选用并称量制取副药剂的蜂蜜，加入50-60份纯水，加热溶解，过滤除去滤渣，将得到的滤液进行加热浓缩，开始沸腾时析出的浑浊泡沫用匙去除，继续沸腾，炼至发生浅红色有光泽的泡沫，用手捻之有粘性而不产生白丝为度；
(3)捏合，将上述炼制好的蜂蜜倒入步骤(1)中的消毒盆内，在倒入蜂蜜的同时用搅拌工具在药粉内朝一个方向圆周搅动，以混匀主药剂和副药剂，并用手趁热搅拌捏合，制成丸块；
(4)搓条，将丸块用手或制丸板搓成长条状的丸条，以便进一步切割为丸剂，丸条的粗细按丸剂的大小而定；
(5)成型，将丸条分割成等量的小粒，再用手或制丸板搓成圆粒即可，搓条时在手或工具上擦抹润滑剂，以避免丸块粘手或粘在工具上；
(6)包装，备好无毒的塑料薄膜或皮纸，将制备好的药丸分个进行包裹。
作为本发明用于止咳化痰的药丸制备方法的进一步改进，所述润滑剂系麻油与黄蜡按3:1加热融合配制而成。
本发明中，各药材的药理药效如下：
川贝母：味苦、甘，性微寒；归肺、心经；质润泄散，降而微升；具有清热化痰，润肺止咳，散结消肿的功效；主治虚劳久咳，肺热燥咳，肺痈吐脓，瘰疬结核，乳痈，疮肿等症。
知母：性味苦、寒，归肺、胃、肾经，具有清热泻火，滋阴润燥的功效，主治热病烦渴，肺热燥咳，骨蒸潮热，内热消渴，肠燥便秘等症。
黄芩：根入药，味苦、性寒，具有清热燥湿，泻火解毒，止血，安胎等功效。主治温热病，上呼吸道感染，肺热咳嗽，湿热黄胆，肺炎，痢疾，咳血，目赤，胎动不安，高血压，痈肿疖疮等症。
炒栀子：性味苦、寒，归心、肺、三焦经。具有护肝，利胆，降压，镇静，止血，消肿等作用。主治泻火除烦，清热利尿，凉血解毒等症。
生石膏：性味辛、干、微寒，归肺、胃经。具有清热泻火，除烦止渴，收敛生肌功效，主治中风寒热，心下逆气惊喘，口干舌焦，不能息，腹中坚痛，产褥金疮等症。
桑白皮：性味甘、寒。入肺经，具有泻肺平喘，行水消肿功效，本品为解热祛痰药，用于急性支气管炎、肺炎、肺气肿、肺水肿等引起的咳喘有效，且有显著利尿作用，并能带出较多的氯化物，对于小便不利、身面浮肿、脚气肿、肾炎水肿用之有效。
瓜蒌：性味甘、微苦、寒。归肺、胃、大肠经。主治清热涤痰，宽胸散结，润燥滑肠等症。
五味子：性味酸、甘、温。归肺、心、肾经，具有收敛固涩，益气生津，补肾宁心功效。主治久嗽虚喘，梦遗滑精，遗尿尿频，久泻不止，自汗，盗汗，津伤口渴，短气脉虚，内热消渴，心悸失眠等症。
橘红：味辛、苦，性温，归肺、脾经，具有理气宽中，燥湿化痰功效，主治咳嗽痰多，食积伤酒，呕恶痞闷等症。
枳实：性味苦酸、寒。归脾、胃、大肠经。具有破气除积，化痰消痞功效；主治食积痰滞不消，气郁胸腹，痞满胀痛，痢疾后重等症。
赤苓：味辛，性温，无毒。入心、脾、膀胱经，具有健脾渗湿功效，主治心肾气虚，神志不守，小便淋沥或不禁，遗泄白浊，胸胁逆满胀渴等症。
甘草：味甘，性平，归心、肺、脾、胃经。具有补脾益气，润肺止咳，缓急止痛，缓和药性之功效。
有益效果
本发明选用对止咳化痰有疗效的多种中药材，川贝母性微寒，清热润燥，化痰止咳，知母甘寒，清肺润燥，共为君药。黄芩清肺热，生石膏泻肺胃之火，炒栀子清解三焦火毒，共为臣药。桑白皮清泻肺热，止咳平喘，瓜蒌润肺化痰止咳，五味子敛肺止咳平喘，橘红理气宽中，燥湿化痰，枳实化痰除痞，赤苓健脾渗湿以除生痰之源，共为佐药。甘草润肺止咳，调和药性而为佐使药。诸药共奏清肺润燥，具有化痰止咳的功效。将蜂蜜通过数道工序处理，杀死蜂蜜内含有的微生物以进行消毒，并且通过加热浓缩增加其粘稠度，同时将泡沫等杂质除去。本发明的制作工艺全部采用原生态中药原材料，对人体无副作用，止咳丸剂针对于咳嗽日久的慢性症状更有针对性，服用方便，成本低廉，经过临床实验证明，本发明药物对于因燥热蕴肺咳嗽日久，痰盛气促的症状有较好的治疗效果。
具体实施方式
为了使本发明的技术方案及优点更加清楚明白，以下结合实施例，对本发明进行进一步详细说明。
实施例1
一种用于止咳化痰的药丸，由主药剂和副药剂混合而成，其中，主药剂按重量百分比由以下组分制成：五味子4份，枳实4份，甘草4份，川贝母25份，知母25份，黄岑15份，橘红10份，桑白皮15份，瓜蒌25份，生石膏25份，炒栀子15份，赤苓5份；副药剂按重量百分比由以下组分制成：蜂蜜260份。
上述用于止咳化痰药丸的制备方法，包括以下步骤：
(1)药材磨粉，按照上述组分要求选用并称量制取主药剂的药材，然后磨成细度为80目的细粉，装入消毒盆中混匀备用；
(2)熬炼蜂蜜，按照上述要求选用并称量制取副药剂的蜂蜜，加入50份 纯水，加热溶解，过滤除去滤渣，将得到的滤液进行加热浓缩，开始沸腾时析出的浑浊泡沫用匙去除，继续沸腾，炼至发生浅红色有光泽的泡沫，用手捻之有粘性而不产生白丝为度；
(3)捏合，将上述炼制好的蜂蜜倒入步骤(1)中的消毒盆内，在倒入蜂蜜的同时用搅拌工具在药粉内朝一个方向圆周搅动，以混匀主药剂和副药剂，并用手趁热搅拌捏合，制成丸块；
(4)搓条，将丸块用手或制丸板搓成长条状的丸条，以便进一步切割为丸剂，丸条的粗细按丸剂的大小而定；
(5)成型，将丸条分割成等量的小粒，再用手或制丸板搓成圆粒即可，搓条时在手或工具上擦抹润滑剂，以避免丸块粘手或粘在工具上，润滑剂系麻油与黄蜡按3:1加热融合配制而成；
(6)包装，备好无毒的塑料薄膜或皮纸，将制备好的药丸分个进行包裹。
实施例2
一种用于止咳化痰的药丸，由主药剂和副药剂混合而成，其中，主药剂按重量百分比由以下组分制成：五味子6份，枳实6份，甘草6份，川贝母35份，知母35份，黄岑25份，橘红20份，桑白皮25份，瓜蒌35份，生石膏35份，炒栀子25份，赤苓15份；副药剂按重量百分比由以下组分制成：蜂蜜300份。
上述用于止咳化痰药丸的制备方法，包括以下步骤：
(1)药材磨粉，按照上述组分要求选用并称量制取主药剂的药材，然后磨成细度为120目的细粉，装入消毒盆中混匀备用；
(2)熬炼蜂蜜，按照上述要求选用并称量制取副药剂的蜂蜜，加入60份纯水，加热溶解，过滤除去滤渣，将得到的滤液进行加热浓缩，开始沸腾时析出的浑浊泡沫用匙去除，继续沸腾，炼至发生浅红色有光泽的泡沫，用手捻之 有粘性而不产生白丝为度；
(3)捏合，将上述炼制好的蜂蜜倒入步骤(1)中的消毒盆内，在倒入蜂蜜的同时用搅拌工具在药粉内朝一个方向圆周搅动，以混匀主药剂和副药剂，并用手趁热搅拌捏合，制成丸块；
(4)搓条，将丸块用手或制丸板搓成长条状的丸条，以便进一步切割为丸剂，丸条的粗细按丸剂的大小而定；
(5)成型，将丸条分割成等量的小粒，再用手或制丸板搓成圆粒即可，搓条时在手或工具上擦抹润滑剂，以避免丸块粘手或粘在工具上，润滑剂系麻油与黄蜡按3:1加热融合配制而成；
(6)包装，备好无毒的塑料薄膜或皮纸，将制备好的药丸分个进行包裹。
实施例3
一种用于止咳化痰的药丸，包括主药剂和副药剂混合而成，其中，主药剂按重量百分比由以下组分制成：五味子5份，枳实5份，甘草5份，川贝母30份，知母30份，黄岑20份，橘红15份，桑白皮20份，瓜蒌30份，生石膏30份，炒栀子20份，赤苓10份；副药剂按重量百分比由以下组分制成：蜂蜜280份。
上述用于止咳化痰药丸的制备方法，包括以下步骤：
(1)药材磨粉，按照上述组分要求选用并称量制取主药剂的药材，然后磨成细度为100目的细粉，装入消毒盆中混匀备用；
(2)熬炼蜂蜜，按照上述要求选用并称量制取副药剂的蜂蜜，加入55份纯水，加热溶解，过滤除去滤渣，将得到的滤液进行加热浓缩，开始沸腾时析出的浑浊泡沫用匙去除，继续沸腾，炼至发生浅红色有光泽的泡沫，用手捻之有粘性而不产生白丝为度；
(3)捏合，将上述炼制好的蜂蜜倒入步骤(1)中的消毒盆内，在倒入蜂蜜的同时用搅拌工具在药粉内朝一个方向圆周搅动，以混匀主药剂和副药剂，并用手趁热搅拌捏合，制成丸块；
(4)搓条，将丸块用手或制丸板搓成长条状的丸条，以便进一步切割为丸剂，丸条的粗细按丸剂的大小而定；
(5)成型，将丸条分割成等量的小粒，再用手或制丸板搓成圆粒即可，搓条时在手或工具上擦抹润滑剂，以避免丸块粘手或粘在工具上，润滑剂系麻油与黄蜡按3:1加热融合配制而成；
(6)包装，备好无毒的塑料薄膜或皮纸，将制备好的药丸分个进行包裹。
以上所述，仅是本发明的较佳实施例而已，并非对本发明作任何形式上的限制，虽然本发明已以较佳实施例揭露如上，然而并非用以限定本发明，任何熟悉本专业的技术人员，在不脱离本发明技术方案范围内，当可利用上述揭示的技术内容作出些许更动或修饰为等同变化的等效实施例，但凡是未脱离本发明技术方案内容，依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与修饰，均仍属于本发明技术方案的范围内。

Claims (3)

  1. 一种用于止咳化痰的药丸，其特征在于：由主药剂和副药剂混合而成，其中，主药剂按重量百分比由以下组分制成：五味子4-6份，枳实4-6份，甘草4-6份，川贝母25-35份，知母25-35份，黄岑15-25份，橘红10-20份，桑白皮15-25份，瓜蒌25-35份，生石膏25-35份，炒栀子15-25份，赤苓5-15份；副药剂按重量百分比由以下组分制成：蜂蜜260-300份。
  2. 根据权利要求1所述用于止咳化痰的药丸的制备方法，其特征在于，包括如下步骤：
    (1)药材磨粉，按照权利要求1中的组分要求选用并称量制取主药剂的药材，然后磨成细度为80-120目的细粉，装入消毒盆中混匀备用；
    (2)熬炼蜂蜜，按照权利要求1中的要求选用并称量制取副药剂的蜂蜜，加入50-60份纯水，加热溶解，过滤除去滤渣，将得到的滤液进行加热浓缩，开始沸腾时析出的浑浊泡沫用匙去除，继续沸腾，炼至发生浅红色有光泽的泡沫，用手捻之有粘性而不产生白丝为度；
    (3)捏合，将上述炼制好的蜂蜜倒入步骤(1)中的消毒盆内，在倒入蜂蜜的同时用搅拌工具在药粉内朝一个方向圆周搅动，以混匀主药剂和副药剂，并用手趁热搅拌捏合，制成丸块；
    (4)搓条，将丸块用手或制丸板搓成长条状的丸条，以便进一步切割为丸剂，丸条的粗细按丸剂的大小而定；
    (5)成型，将丸条分割成等量的小粒，再用手或制丸板搓成圆粒即可，搓条时在手或工具上擦抹润滑剂，以避免丸块粘手或粘在工具上；
    (6)包装，备好无毒的塑料薄膜或皮纸，将制备好的药丸分个进行包裹。
  3. 根据权利要求2所述用于止咳化痰的药丸的制备方法，其特征在于：所述润滑剂系麻油与黄蜡按3:1加热融合制成。
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