WO2018145870A1 - Système pour le prélèvement stérile de fluide corporel - Google Patents

Système pour le prélèvement stérile de fluide corporel Download PDF

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Publication number
WO2018145870A1
WO2018145870A1 PCT/EP2018/051125 EP2018051125W WO2018145870A1 WO 2018145870 A1 WO2018145870 A1 WO 2018145870A1 EP 2018051125 W EP2018051125 W EP 2018051125W WO 2018145870 A1 WO2018145870 A1 WO 2018145870A1
Authority
WO
WIPO (PCT)
Prior art keywords
coupling
syringe
closure
tip
piston rod
Prior art date
Application number
PCT/EP2018/051125
Other languages
German (de)
English (en)
Inventor
Friedrich Pipelka
Original Assignee
Friedrich Pipelka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Friedrich Pipelka filed Critical Friedrich Pipelka
Priority to DE112018000725.1T priority Critical patent/DE112018000725A5/de
Publication of WO2018145870A1 publication Critical patent/WO2018145870A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/155—Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150236—Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150244—Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/15074—Needle sets comprising wings, e.g. butterfly type, for ease of handling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A61J1/1418—Threaded type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1475—Inlet or outlet ports
    • A61J1/1487—Inlet or outlet ports with friction fit, e.g. connecting tubes directly to a protruding port
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2055—Connecting means having gripping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2058—Connecting means having multiple connecting ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly

Definitions

  • the invention relates to a system for the sterile decrease of Ko er intricatekeit and for separating at least a portion of the removed body fluid after the
  • the document US 5,147,329 discloses a system for the removal of body fluid and for separating a part of the removed body fluid.
  • the system includes a take-off syringe, a container formed by a vacuum container, and an intermediate member.
  • the take-off syringe has a housing and a piston attached to a piston rod, which is displaceable by changing a volume of a bounded by the housing and the piston chamber in the housing. By moving the piston in the chamber, body fluid can be drawn into or discharged from the chamber.
  • a cannula is attached to the take-off syringe via a luer connection.
  • a piston channel is formed, which extends from the piston in the longitudinal direction through the piston rod and opens into a female-luer connection part.
  • Intermediate member has a Male-Luer connector and a male part with a tip, wherein the Male-Luer connector and the tip of the male part are connected via a connection channel.
  • the female luer connection part and the male luer connection part form a first clutch, wherein closing the first clutch, the intermediate element is coupled to the take-off syringe and the connecting channel and the piston channel can be brought into fluid communication.
  • the vacuum container has a closure part with a closure.
  • the insertion part and the closure part form a second coupling, wherein the vacuum container can be coupled to the intermediate element by closing the second coupling. Upon closing the second coupling, the tip of the insertion member pierces the closure of the closure member, whereby an interior of the vacuum container is in fluid communication with the connection channel.
  • the female-luer connection part on the piston rod is closed with a stopper in order to draw air through the piston passage when the take-off syringe is pulled on avoid. If a certain amount of body fluid has been drawn into the take-off syringe, the stopper is removed in a further step and the take-off syringe is coupled to the intermediate element by closing the first coupler. Alternatively, body fluid can also be taken off with an intermediate element coupled to the take-off syringe become. Subsequently, by closing the second coupling, the vacuum container is coupled to the intermediate element. Due to the vacuum formed in the vacuum container, body fluid is sucked into the vacuum container until it is full or until the vacuum formed in it has dropped so much that it is no longer sufficient to draw more body fluid into the vacuum container. After filling, the
  • Training is a very furnmelige affair and entices a person using the system to jerky movements when removing. This not only increases the risk of injury to a person using the system, but also to persons who are in the near field of the person using the system.
  • Contamination and without the risk of contamination can be removed and at least a portion of the removed Kö ⁇ er intricatekeit can be separated into more containers.
  • the first coupling has the same elements as the second coupling, wherein the insertion part of the first coupling is formed on the intermediate element and the closure part of the first coupling is formed on the piston rod.
  • the system according to the invention is very light and easy to handle and a decrease in body fluid and a separation of at least a portion of the withdrawn fluid can be performed quickly and safely.
  • the tip of the male parts is formed very thin, wherein the closure is formed so that an opening formed by the tip when closing one of the clutches in the closure after opening the clutch and the associated
  • the closure is advantageously formed by an elastomer or a foam.
  • the tip is preferably made of plastic or stainless steel and / or received in the connecting element, that this does not protrude from the connecting element to avoid injury.
  • the connecting element to avoid injury.
  • Einich testeril advantageously on a sleeve which is spaced around the tip and protrudes from the intermediate element further than the tip.
  • the sampling syringe and the at least one container after opening the clutches are immediately closed to the outside. Contamination of the body fluid or leakage of Kö ⁇ erstattkeit from the collection syringe or the at least one container is reliably prevented by the closure at any time. Also, after opening the first clutch, superfluous body fluid may be forced directly out of the chamber of the take-off syringe by a movement of the plunger decreasing the volume or further liquid may be directly sucked through a movement expanding the chamber.
  • each insertion part has a prestressed part
  • the intermediate element expediently has at least one further insertion part with a tip, which tip adjoins the connection channel.
  • the at least one container is formed by at least one bearing syringe, by a certain amount of absorbed in the chamber of the collection syringe
  • a system in which the at least one container is formed by a take-off syringe is advantageously used in body fluids formed by blood.
  • the system is particularly well suited for the sterile separation of the blood collected by the collection syringe into a serum and blood cake centrifuge and to separate it into several containers.
  • the blood divided into serum and blood cake can be metered in portions from the collection syringe, wherein the respective amount which is separated can be adjusted by the at least one storage syringe.
  • the at least one container is formed by at least one vacuum container.
  • FIG. 1 shows an embodiment variant of the system according to the invention in FIG. 1
  • FIG. 2 shows the embodiment variant of the system according to the invention according to FIG. 1 in the assembled state in a sectional view.
  • FIG. 3 and FIG. 4 show a take-off syringe of the embodiment variant of FIG.
  • FIG. 5 shows the take-off syringe of the embodiment variant of the system according to the invention according to FIG. 1 with a cannula in a perspective view.
  • FIG. 6 and FIG. 7 show the take-off syringe of the system according to the invention according to FIG. 1 in the drawn-up state.
  • FIG. 8 shows the take-off syringe of the system according to the invention according to FIG. 1 with the piston rod in the fixing position in a perspective view.
  • Figure 9 shows the sampling syringe of the system according to the invention according to Figure 1 without Aufziehelement in a perspective view.
  • Figure 10 and Figure 11 show the sampling syringe of the system according to the invention according to Figure 1 without Aufziehelement in a centrifuge tube.
  • FIGS. 12 to 14 show the system according to the invention according to FIG. 1 in sectional views.
  • FIG. 1 shows a variant of the embodiment of the system 1 according to the invention in an unassembled state in a perspective view.
  • the system 1 comprises a take-off syringe 2, an intermediate element 24, two containers formed by bearing sprayers 25, a cannula 16, a pulling-on element 11, a third insertion part 17 and three second ones
  • Closure parts 9 The cannula 16, the third insertion part 17 and the mounting element 11 are shown in FIG.
  • Figure 2 shows the embodiment of the system 1 according to the invention according to Figure 1 in a sectional view.
  • the bearing syringes 25 each comprise a housing 39 and a piston 40, wherein the piston 40 is movably mounted in the housing 39.
  • the take-off syringe 2 comprises a housing 3, a cover 44, a piston 4 and a piston rod 5.
  • the piston 4 is connected to the piston rod 5 and is under
  • the system 1 further comprises a first clutch 30, two second clutches 36, a third clutch 20 shown in FIG. 5 and four fourth clutches 43.
  • the first coupling 30 is formed by a first insertion part 26 and a first closure part 13, wherein the first insertion part 26 on the intermediate element 24 and the first
  • Closure part 13 is formed on the piston rod 5 of the take-off syringe 2.
  • the two second clutches 36 are each formed by a second insertion part 27 and by a second closure part 9, wherein a second closure part 9 is connected in each case with a Luer connection formed by a fourth clutch 43 to the housing 39 of one of the bearing sprayers 25 and the two second Einichtile 27 at the
  • the third coupling 20 is shown in FIG. 5 and formed by the third insertion part 17 and by a second closure part 9, the second closure part 9 having a Luer connection formed by a fourth coupling 43 with the housing 3
  • Acceptance syringe 2 is connected and the third insertion part 17 is connected to a luer connection formed by a fourth coupling 43 with a hose 21 of the cannula 16.
  • the tube 21 of the cannula 16 and the third insertion part 17 are shown in FIG.
  • the second closure parts 9 each have a closure 10, which by a
  • FIG. 3 and FIG. 4 show the take-off syringe 2 of the embodiment variant of FIG.
  • inventive system 1 according to Figure 1 with attached to the piston rod 5
  • Figure 3 shows a side view of the take-off syringe 2
  • Figure 4 shows a sectional view of the take-off syringe 2 along the section A-A in Figure 3.
  • a piston channel 12 is formed, which extends from the chamber 6 in the longitudinal direction through the piston rod 5 and opens into the first closure part 13.
  • the first closure part 13 has a closure 14, which is formed by an elastomer and closes an inlet of the piston channel 12. Further, 5 locking grooves 7 are formed on a shaft of the piston rod.
  • FIG. 5 shows the take-off syringe 2 of the embodiment variant of the system 1 according to the invention with a cannula 16 in a perspective view according to FIG.
  • the cannula 16 is formed by a butterfly known to those skilled in the art, but may also be formed by a simple needle.
  • the third insertion part 17 has a tip, not shown, which is surrounded by a sleeve 18. Laterally on the third insertion part 17 snap elements 19 are provided.
  • the snap element 19 are formed on the closure part 9.
  • FIG. 6 and FIG. 7 show the take-off syringe 2 of the system 1 according to the invention in the drawn-up state, FIG. 6 showing a side view of the take-off syringe 2 and FIG. 7 a sectional view of the take-off syringe 2 along the section B-B in FIG.
  • FIG. 8 shows the take-off syringe 2 of the system 1 according to the invention according to FIG. 1 with the piston rod 5 located in the fixing position in a perspective view.
  • the cover 44 of the take-off syringe 2 has longitudinal guides 22, in which the shank of the piston rod 5 and a shank of the pull-up element 11 are guided.
  • Piston rod 5 is fixed in a longitudinal direction to the take-off syringe 2 and the
  • Release element 11 can be solved by the piston rod 5.
  • Piston rod 5 in a rotational movement, wherein after the release, the mounting element 11 can be removed in the longitudinal direction of the piston rod 5.
  • the cover 44 is formed integrally with the housing 3 of the take-off syringe 2.
  • Figure 9 shows the sampling syringe 2 of the system 1 according to the invention according to Figure 1 without Aufziehelement 11 in a perspective view.
  • FIG. 10 and FIG. 11 show the take-off syringe 2 of the system 1 according to the invention in FIG. 1 without a pull-off element 11 in a centrifuge tube 23,
  • FIG. 10 a side view of the centrifuge tube 23 and
  • FIG. 11 a sectional view of the centrifuge tube 23
  • FIGS. 12 to 14 show the system 1 according to the invention according to FIG. 1 in sectional views.
  • the Einichtile 26 and 27 each have tips 28 which are surrounded by sleeves 29.
  • the sleeve 29 of the first insertion part 26 is in the figures 12 to 14 due to Sectional view not shown.
  • the sleeves 29 protrude further from the intermediate member 24 than the tips 28, thereby preventing inadvertent puncture by the tips 28 by a person using the system 1.
  • snap elements 42 are formed at the sleeves 29 of the second Einichtile 27.
  • the system 1 according to the invention further comprises a connecting element 41, by means of which the pistons 40 of the bearing sprayers 25 are connected.
  • Connecting element 41 has the advantage that both pistons 40 of the bearing sprayers 25 can be actuated simultaneously to the same extent, whereby a uniform
  • a person using the system 1, hereinafter referred to as a doctor takes in a first step the delivery syringe 2 with the closure 9 already fastened thereto via the fourth coupling 43 and with it plugged on
  • the doctor takes the butterfly with already attached to the butterfly via the fourth clutch 43 third insertion part 17 from another in the figures not shown sterile Ve ackung and couples the butterfly by closing the third clutch 20 with the take-off syringe 2 Closing the coupling 20 pierces the tip of the third insertion part 17 the closure 10 of the second closure part 9 connected to the take-off syringe 2, whereby the chamber 6 is in fluid communication with an interior of the hose 21 of the butterfly.
  • the clutch 20 is closed, the snap elements 19 fix the third insertion part 17 on the second closure part 9, as a result of which the butterfly is firmly connected to the take-off syringe 2. See figure 5.
  • the butterfly is introduced by the doctor into a ⁇ , in this case a vein, a patient and blood removed by a chamber 6 expanding movement of the piston 4 by means of the Aufziehelements 11.
  • the take-off syringe 2 is filled to a maximum volume of the chamber 6 with blood, whereby the piston rod 5 by the doctor after the
  • Blood collection in the fixing position is rotatable to fix the piston rod 5 in the axial direction relative to the housing 3 of the take-off syringe 2.
  • the third clutch 20 is opened again by actuating the snap elements 19 and pulling on the third insertion part 17 and the butterfly is again decoupled from the take-off syringe 2.
  • the butterfly is advantageously disposed of in an external medical waste bin.
  • the closure 10 of the closure part 9 closes immediately after the
  • Piston rod 5 is released from the piston rod 5 and the take-off syringe 2 is packed into a centrifuge tube 23.
  • the take-off syringe 2 is centrifuged in a centrifuge, not shown, until the blood divides into its components blood cake and serum. See Figures 10 and 11.
  • the bearing syringes 25 are removed with second fasteners 9 already fastened thereto via the fourth coupling 43 and the intermediate element 24 is removed from further sterile packagings not shown on the figures and coupled together by closing the second couplings 36.
  • the tip 28 of a second insertion part 27 pierces a closure 10 of the second closure parts 9 of the bearing spraying jigs 25.
  • an interior 37 of the bearing spraying devices 25 is connected to the connection channel 31 of FIG.
  • the take-off syringe 2 is removed from the centrifuge tube 23 and coupled to the intermediate element 24 by closing the first coupling 30.
  • the tip 28 of the first insertion part 26 pierces the closure 14 of the first closure part 13.
  • a connection channel 31 formed in the intermediate element 24 and the piston channel 12 are in fluid communication with each other.
  • the bearing syringes 25 are decoupled from the intermediate member 24 by opening the second clutch 36, whereby the separated blood cake or the separated serum in the bearing syringes 25 can be supplied for further use. This ensures the advantage of easy handling and sterility of the removed body fluid throughout the handling.
  • additional bearing syringes 25 can be coupled to the intermediate member 24 to separate blood cake or serum.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Manufacturing & Machinery (AREA)
  • Fluid Mechanics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne un système (1) pour le prélèvement stérile de fluide corporel et pour séparer une partie du fluide corporel prélevé. Le système (1) comprend une seringue de prélèvement (2) munie d'un coulisser (3) et d'un piston (4) fixé sur une tige de piston (5) et qui peut réalisé à l'intérieur du corps (3), un canal de piston (12) étant conçu dans la tige de piston (5) lequel s'étend longitudinalement dans la tige de piston (5), un élément intermédiaire (24) pouvant être couplé à la tige de piston (5) par l'intermédiaire d'un premier accouplement (30) et un récipient pouvant être couplé à l'élément intermédiaire (24) par l'intermédiaire d'un second accouplement (36). Le second accouplement (36) présente une partie de perçage (27) munie d'une pointe (28) et d'une partie de fermeture (9) munie d'un bouchon (10). Le premier accouplement (30) est également conçu comme le second accouplement (36).
PCT/EP2018/051125 2017-02-08 2018-01-17 Système pour le prélèvement stérile de fluide corporel WO2018145870A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE112018000725.1T DE112018000725A5 (de) 2017-02-08 2018-01-17 System zur sterilen Abnahme von Körperflüssigkeit

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA50101/2017 2017-02-08
ATA50101/2017A AT519610B1 (de) 2017-02-08 2017-02-08 System und Verfahren zur sterilen Abnahme von Körperflüssigkeit

Publications (1)

Publication Number Publication Date
WO2018145870A1 true WO2018145870A1 (fr) 2018-08-16

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PCT/EP2018/051125 WO2018145870A1 (fr) 2017-02-08 2018-01-17 Système pour le prélèvement stérile de fluide corporel

Country Status (3)

Country Link
AT (1) AT519610B1 (fr)
DE (1) DE112018000725A5 (fr)
WO (1) WO2018145870A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147329A (en) * 1987-02-11 1992-09-15 Brannon James K Intravenous access devices
WO2014177347A1 (fr) * 2013-05-03 2014-11-06 Hubertus Goller Gesellschaft M.B.H. Dispositif de transfert

Family Cites Families (2)

* Cited by examiner, † Cited by third party
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