WO2018101788A2 - Ensemble de solution de perfusion ayant une fonction de fiole et contenant une bouteille d'injection - Google Patents

Ensemble de solution de perfusion ayant une fonction de fiole et contenant une bouteille d'injection Download PDF

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Publication number
WO2018101788A2
WO2018101788A2 PCT/KR2017/013999 KR2017013999W WO2018101788A2 WO 2018101788 A2 WO2018101788 A2 WO 2018101788A2 KR 2017013999 W KR2017013999 W KR 2017013999W WO 2018101788 A2 WO2018101788 A2 WO 2018101788A2
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WO
WIPO (PCT)
Prior art keywords
needle
vial
cap
injection
holder
Prior art date
Application number
PCT/KR2017/013999
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English (en)
Korean (ko)
Other versions
WO2018101788A3 (fr
Inventor
이영재
이호재
Original Assignee
주식회사 제이씨텍
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Application filed by 주식회사 제이씨텍 filed Critical 주식회사 제이씨텍
Publication of WO2018101788A2 publication Critical patent/WO2018101788A2/fr
Publication of WO2018101788A3 publication Critical patent/WO2018101788A3/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407—Infusion of two or more substances
    • A61M5/1409—Infusion of two or more substances in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • A61M5/1626—Needle protectors therefor

Definitions

  • the present invention relates to a vial visceral vial set.
  • Korean Patent No. 10-0569223 such a structure is provided with a connecting member in communication with the drug container, a plastic container having a discharge member for discharging the chemical at the other end; And a communication needle connected to the connection member and inserted into the connection member through the medicine container of the protective cap for receiving the medicine container and the stopper to communicate the medicine container with the sap;
  • the protective cap part is a fixed cap and a moving cap are combined, it is difficult to assemble, the component is complicated and has a problem in sealing.
  • the dissolution liquid cap is coupled to the inlet of the dissolution liquid container known as Korean Patent Registration No. 10-1640159, a communication member is placed inside the dissolution liquid cap, and a communication member is placed on the communication member and the upper portion of the dissolution liquid cap.
  • the penetrating needle penetrates the medicine in the medicine container through the needle insertion part through the communication member, and is supplied to the solution container.
  • the bidirectional injection needle has the advantage of allowing the solution container and the medicine container to pass through, but has a large number of parts and a sealing. Securing the castle is not easy.
  • Korea Utility Model Registration No. 20-0455090 is known as a pouch stopper used in the pouch bag, and the structure of combining the vial to the sap set is disclosed in Korea Patent Publication No. 10-2006-0123372, Korea Utility Model Registration No. 20-0478043 , And Korea Patent Registration No. 10-0569223, but the vial is a structure that is coupled to the outside of the sap container is not good storage, difficult packaging, and difficult to use, such as unintended mixing of the vial medicine during impact There is this.
  • the present invention is to solve this, an object of the present invention in the pouch infusion container is installed in the inlet of the inlet, the outlet portion of the pouch container, the injection port fixed to the needle protruding vertically in the lower portion of the infusion container
  • the inner cap with the sealing part in the center is coupled to the needle holder which fixes the needle, and the packing holder which moves vertically on the upper part of the sealing film of the inner cap, and the packing that seals the inlet cap of the injection bottle and the sealing in the packing holder,
  • the packing holder and the injection bottle containing the packing are accommodated in the outer cap which is screwed together with the inner cap, and after separating the C-type crevice that provides the vertical space to lower the outer cap from the fixed position, and lowering the outer cap, the packing holder and the vial together with the outer cap
  • Another object of the present invention is a pouch infusion container, the inlet of the inlet, the outlet portion of the pouch container is installed in the inlet, the injection port fixed to the needle protruding vertically in the lower portion and the needle to communicate with the fluid container, the needle fixed Combine the inner cap with the sealing part in the center of the needle holder, the packing holder which moves vertically on the sealing film of the inner cap, the packing holder with the inlet cap of the vial and the sealing seal, and the packing holder to accommodate the packing and the injection
  • the vial is housed in an outer cap that is screwed into the inner cap, and after separating the C-type crevice that provides the vertical space to lower the outer cap from the fixed position, the screw is lowered by screwing the outer cap into the exposed vertical space and the packing holder with the outer cap.
  • the lower needle penetrates the sealing membrane and the injection liquid Since functions to be mixed with the contents of the container and automatically, even when you insert the needle in the injection vial novice users do not need to manipulate the needles to specific intended to provide an injection vial vials set of built-in receiver that features ever available.
  • Another object of the present invention is a needle fixed to the inlet of the pouch container, coupled to the inner cap fusion fusion to the needle holder for supporting the needle, the inner cap has a sealing film surrounding the needle to isolate the outside and the needle to penetrate the external bacteria Is withheld,
  • An inlet installed at the inlet of the pouch container
  • the injection hole is a needle that is installed in the needle vertically on the needle holder fused to the inlet of the pouch container;
  • An inner cap coupled to the needle holder of the needle and having a sealing film therein to receive the needle therein and to pass the needle when lowered;
  • An outer cap to cope with the inner cap so as to be movable and to hold the injection bottle inside;
  • the lower portion provides a vial function injection vial set containing a vial holder that seals the injection bottle inlet stopper and the sealing membrane and contains a packing having a vertical through the center do.
  • the present invention in the pouch infusion container provided with an inlet at the inlet of the pouch container, an outlet at the outlet portion, the injection needle is fixed to the needle protruding perpendicularly to the lower portion and the needle is in communication with the fluid container, the needle is fixed Combine the inner cap with the sealing part in the center of the needle holder, the packing holder which moves vertically on the sealing film of the inner cap, the packing holder with the inlet cap of the vial and the sealing seal, and the packing holder to accommodate the packing and the injection
  • the vial is accommodated in the outer cap which is screwed into the inner cap, and after separating the C-type crevice which provides a vertical space to lower the outer cap at the fixed position, and lowering the outer cap, the packing holder and the injection bottle are lowered together with the outer cap and the sealing film is lowered.
  • the needle penetrates the sealing membrane so that the injection liquid is automatically mixed with the contents of the fluid container. It provides the convenience and safety of use.
  • the inlet of the pouch container, the inlet port, the outlet portion of the pouch infusion container is installed in the outlet, the injection port is fixed to the needle protruding vertically protruding in the lower portion and the needle to communicate with the fluid container, the needle holder for fixing the needle
  • the inner cap is combined with the inner cap, and the upper part of the inner cap sealing film has a packing holder that moves vertically, and the packing holder has an inlet cap of the injection bottle and a seal that seals the packing.
  • the outer cap which is screwed together with the outer cap, and separates the C-type crevice that provides the vertical space to lower the outer cap from the fixed position, and then lowers it by screwing the outer cap into the exposed vertical space, and the packing holder and the injection bottle together with the outer cap
  • the sealing film is lowered while being vertically lowered, the needle located at the bottom penetrates the sealing film, and the injection liquid is in the fluid container. Since functions to be mixed with water and automatically, even when you insert the needle in the injection vial novice users do not need to manipulate the needles to specific and ever available.
  • the needle is fixed at the inlet of the pouch container, and the inner cap coupled to the rim is fused to the needle holder supporting the needle, and the inner cap has a sealing film surrounding the needle to isolate the outside and the needle so that the infiltration of external bacteria is prevented.
  • the C-type creep keeps the outer cap at a certain height to prevent the sealing film from being damaged from the needle. Has durability.
  • FIG. 1 is an exploded perspective view of the present invention.
  • FIG. 2 is a cross-sectional view of the assembled state of the present invention.
  • Figure 3 is an enlarged cross-sectional view of the inlet of the present invention.
  • FIG. 4 is a cross-sectional view of the state of use of FIG.
  • the injection hole is a needle that is installed in the needle vertically on the needle holder fused to the inlet of the pouch container;
  • An inner cap coupled to the needle holder of the needle and having a sealing film therein to receive the needle therein and to pass the needle when lowered;
  • An outer cap to cope with the inner cap so as to be movable and to hold the injection bottle inside;
  • a vial function coupled to the upper portion of the sealing membrane of the inner cap, and a lower portion of the vial function, including a packing holder for sealingly coupling the injection bottle inlet stopper and the sealing membrane and accommodating a packing having a vertical hole in the center thereof. to provide.
  • An inlet 30 installed in the pouch container 10 inlet 14;
  • the injection hole 30 includes a needle part 40 having a needle 44 vertically mounted on a needle holder 42 fused to the inlet 14 of the pouch container 10;
  • An inner cap 50 coupled to the needle holder 42 of the needle 40 and accommodating the needle 44 therein and having a sealing film 52 through which the needle passes when being lowered;
  • An outer cap 60 to coax with the inner cap 50 and to accommodate the injectable bottle 70 upside down;
  • the lower portion of the infusion cap 70 and the sealing cap 52 and the sealing membrane 52 has a vertical through-hole 82 in the center It comprises a packing holder 90 for receiving the packing (80).
  • the sealing film 52 formed to block the inner diameter inside the inner cap 50 is convex upward and convex portion 53 concave downward when the packing holder 90 is pressed,
  • a ring plate portion 54 provided in an upper surface of the convex portion 53 in a ring shape
  • the ring plate 54 includes a domed protrusion 55 protruding from the inner diameter of the ring plate 54 to fit into the vertical through hole 82 of the packing 80.
  • the packing holder 90 accommodates the shoulder of the injection bottle 70 and a vertical guide 92 of a groove or protrusion shape is added to the outer surface of the packing holder 90 to move vertically with the inner cap 50.
  • the bottom plate 98 is supported by the ring plate portion 54 at the lower end of the tapered portion 96 and has a protrusion insertion hole 97.
  • the inner cap 50 corresponding to the vertical guide 92 having a groove or protrusion perpendicular to the outer surface of the tubular portion 94 of the packing holder 90 forms a protrusion or groove and near the edge of the sealing film 52. It forms a moving guide 56 leading to.
  • the needle holder 42 of the needle part 40 is a tubular holder tube 45 fused to the inlet 14 of the pouch container 10, and is coupled to an upper end of the holder tube 45 to the needle tube 43. It comprises a support plate 47 for supporting the needle head portion 46 having a penetrating needle hole 48, and a coupling dam 49 protruding to engage the inner cap 50 on the upper edge of the support plate 47. .
  • the lower end of the inner cap 50 fixed to the outer diameter of the coupling dam 49 and the outer cap 60 has an inner vial of the vial function, characterized in that the horizontal ring 57 is formed integrally with the seed-type creep 100. Built-in Infusion Set.
  • the seam creep 100 is configured to cover the outer diameter of the inner cap 50 between the lower end of the outer cap 60 and the upper portion of the horizontal ring 57 and to be separated from the inlet horizontally when pulled outward.
  • a handle ring protruding to the opposite side of the open portion to the middle portion of the C-type creep 100 to facilitate the separation, but may be in another form to perform a pulling function such as a ring or a protrusion.
  • the bottom between the coupling dam 49 and the needle 44 forms an inclined surface 49a which is inclined downward to face the needle 44 at the coupling dam 49, and the inclined surface 49a and the needle 44. It is good to form the inclined through-hole 49b in the circumference.
  • the holder tube 45 and the needle holder 42 of the needle part 40 in the present invention are fused to be sealed with the inlet 14 of the pouch container 10. Since the welding technique itself is a known technique, only the welding technique will be described.
  • the support plate 47 of the needle holder 42 of the present invention and the horizontal ring 57 of the inner cap 50 are also fused.
  • hooking or screwing means it is also possible to use hooking or screwing means, but in the case of medicines it is preferable to weld to provide sealing and sealing properties.
  • the sap is added in advance, and the outlet and the inlet are added to the pouch container 10 to seal the inlet 14 outside the outlet 12.
  • the seed-type creep 100 In use, holding the handle of the seed-type creep 100 and pulling horizontally to the opposite side of the opening, the seed-type creep 100 is separated to expose the lower end of the inner cap 50 and the horizontal ring 57. Since the space is created by the height of the seed-type creep 100, when the outer cap 60 is turned like a screw, the outer cap 60 is screwed with the inner screw of the outer cap 60 along the outer thread 58 of the inner cap 50. Descend.
  • the packing 80 is pushed and the packing 80 is rotated while pushing the packing holder 90, but the outer surface of the packing holder 90 has a vertical guide 92, and the vertical guide 92 has an inner diameter of the inner cap 50. Since the movement guide 56 is coupled to the concave-convex coupling, the vertical guide 92 is lowered vertically. In this case, as the protrusion insertion hole 97 of the vertical through hole 82 and the bottom plate 98, as shown in FIG. 3, the domed protrusion 55 is inserted into the protrusion.
  • the bottom plate 98 of the packing holder 90 pushes the ring plate portion 54 downward to start the convex portion 52 to be concave.
  • the tip of the needle 44 is drilled in the domed protrusion 55 in a fixed state, and then the needle 44 drills the inlet plug 72 of the injection bottle 70 to form a state of FIG. 4.
  • the medicine of the injection vial is naturally supplied through the injection hole 43 of the needle 44 and mixed with the sap via the injection hole 48.
  • the transfusion of the transfusion container moves to the space between the sealing membrane 52 and the support plate 47 through the injection needle 43 of the needle 44.
  • the bottom of the support plate 47 forms an inclined surface 49a
  • the bottom of the inclined surface 49a forms an inclined through-hole 49b communicating with the interior of the infusion container, and then returns to the inside of the infusion container. It acts as a way to eliminate the impression that flowed down.
  • the vial function vial vial set of the present invention as described above provides hygiene, convenience and safety of use, enables a user to use even without a user's needle, and the sealing film is broken from the needle. As it prevents and has durability, industrial applicability is high.

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Bag Frames (AREA)

Abstract

La présente invention concerne un ensemble de solution de perfusion ayant une fonction de flacon et contenant une bouteille d'injection, l'ensemble de solution de perfusion comportant: une ouverture de décharge (20) installée à la sortie (12) d'un contenant en forme de poche (10); et une ouverture d'injection (30) formée à l'entrée (14) du contenant en forme de poche (10), l'ouverture d'injection (30) comprenant: une partie d'aiguille d'injection (40) présentant une aiguille d'injection (44) installée verticalement au-dessus d'un support d'aiguille d'injection (42) thermolié à l'entrée (14) du contenant en forme de poche (10); un capuchon interne (50) couplé au support de l'aiguille d'injection (42) de la partie aiguille d'injection (40), l'aiguille d'injection (44) étant contenue dans le capuchon interne (50), et le capuchon interne (50) comprenant un film d'étanchéité (52) que l'aiguille d'injection traverse lorsqu'elle descend; un capuchon externe (60) configuré pour pouvoir se déplacer vers le haut/vers le bas de manière coaxiale avec le capuchon interne (50), le capuchon externe (60) contenant une bouteille d'injection (70) à l'envers; et un support de serrage (90) couplé à la partie supérieure du film d'étanchéité (52) du capuchon interne (50) pour pouvoir se déplacer verticalement, la partie inférieure du support de serrage (90) scellant/accouplant un capuchon d'entrée (72) de la bouteille d'injection (70) et le film d'étanchéité (52), et le support de serrage (90) contenant une garniture (80) qui a un trou traversant vertical (82) en son centre.
PCT/KR2017/013999 2016-12-01 2017-12-01 Ensemble de solution de perfusion ayant une fonction de fiole et contenant une bouteille d'injection WO2018101788A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2016-0162752 2016-12-01
KR1020160162752A KR101927194B1 (ko) 2016-12-01 2016-12-01 바이알기능의 주사약병 내장 수액세트

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WO2018101788A2 true WO2018101788A2 (fr) 2018-06-07
WO2018101788A3 WO2018101788A3 (fr) 2018-07-19

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KR (1) KR101927194B1 (fr)
CN (1) CN108126256B (fr)
WO (1) WO2018101788A2 (fr)

Cited By (1)

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CN113624443A (zh) * 2021-07-21 2021-11-09 西北工业大学 一种用于水下发射的发射筒筒口密封装置及安装方法

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KR200497888Y1 (ko) * 2021-09-27 2024-03-26 윤지영 바이알 홀더

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US5429614A (en) * 1993-06-30 1995-07-04 Baxter International Inc. Drug delivery system
JP3497800B2 (ja) * 1999-10-14 2004-02-16 塩谷エムエス株式会社 溶解液容器
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AT503142B1 (de) * 2006-01-18 2009-05-15 Friedrich Ing Pipelka Behälter zur einbringung zumindest eines unsterilen gefässes in einen sterilen bereich
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KR101640159B1 (ko) * 2014-09-04 2016-07-18 주식회사 대웅제약 일체형 주사 키트

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113624443A (zh) * 2021-07-21 2021-11-09 西北工业大学 一种用于水下发射的发射筒筒口密封装置及安装方法
CN113624443B (zh) * 2021-07-21 2024-05-10 西北工业大学 一种用于水下发射的发射筒筒口密封装置及安装方法

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Publication number Publication date
KR20180062735A (ko) 2018-06-11
CN108126256A (zh) 2018-06-08
CN108126256B (zh) 2020-12-15
WO2018101788A3 (fr) 2018-07-19
KR101927194B1 (ko) 2018-12-11

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