WO2017133037A1 - 一种能增强人体免疫力、抗衰老的保健液及其制备方法 - Google Patents

一种能增强人体免疫力、抗衰老的保健液及其制备方法 Download PDF

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WO2017133037A1
WO2017133037A1 PCT/CN2016/074603 CN2016074603W WO2017133037A1 WO 2017133037 A1 WO2017133037 A1 WO 2017133037A1 CN 2016074603 W CN2016074603 W CN 2016074603W WO 2017133037 A1 WO2017133037 A1 WO 2017133037A1
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health care
plant
care liquid
leaves
syrup
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PCT/CN2016/074603
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English (en)
French (fr)
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程雪娇
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程雪娇
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
    • A23L2/04—Extraction of juices
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
    • A23L2/08—Concentrating or drying of juices
    • A23L2/12—Concentrating or drying of juices by freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • Health care liquid capable of enhancing human immunity and anti-aging and preparation method thereof
  • the present invention relates to the field of health care products and preparation methods, and particularly to a health care liquid for enhancing human immunity and anti-aging, and a preparation method thereof.
  • Immunity is the body's own defense mechanism, through the cellular and humoral immune mechanisms, the identification and elimination of foreign invading foreign bodies (viruses, bacteria, etc.); treatment of aging, injury, death, degeneration of self-cells; identification and treatment of in vivo mutations Cells and viruses infect cells. It is the body's ability to adapt to the external environment, anti-folk ability and rehabilitation. As the annual growth, the immune function of the body changes to varying degrees, especially the degree of cellular immune function changes more significantly, and low cellular immune function is one of the important causes of aging and various diseases.
  • the health care liquid has the characteristics of balanced nutrition, better absorption effect, convenient use of ij, easy to carry, and the like.
  • the anti-aging, health-enhancing health-care liquid formula and manufacturing process are mainly for the hot extraction of various raw materials in water, although there is a certain health care effect, but the process is unreasonable and has health care.
  • the active substance of the action is lost, and the active ingredient can only be ingested by about 20%, and the effect is not satisfactory.
  • anti-aging and immune-enhancing health care fluids with better effects are needed to meet the needs of people's modern life.
  • An object of the present invention is to provide a health care liquid capable of enhancing human immunity and anti-aging, and a solution for the preparation method thereof
  • the present invention provides a health care liquid capable of enhancing human immunity and anti-aging, which is calculated by mass percentage, and the health care liquid comprises 30 ⁇ 3 ⁇ 4-60 ⁇ 3 ⁇ 4 plant stock solution, 3 ⁇ 3 ⁇ 4-8 ⁇ 3 ⁇ 4 wines. Alcohol base, 0 ⁇ 3 ⁇ 4-15 ⁇ 3 ⁇ 4 excipients, the rest is water.
  • the health care liquid comprises, by mass percentage, 40% of the plant stock solution, 5% of the wine base, 12% of the excipient, and the balance being water.
  • the plant stock solution is a blueberry leaf extract or a blueberry leaf extract having a mass ratio of 1:1, and a ginkgo leaf extract.
  • the auxiliary material is syrup and honey having a mass ratio of 5:3.
  • the syrup is any one of sucrose syrup, fructose syrup, xylitol syrup or sucrose syrup, fructose syrup and xylitol syrup in a mass ratio of 1:1:1.
  • the honey is refined honey.
  • the present invention also provides a method for preparing a health care liquid capable of enhancing human immunity and anti-aging, comprising: [0013] S10, selecting a plant leaf that meets the requirements, and immersing 0.5_2 small sputum after cleaning;
  • step S10 the plant leaves treated in step S10 are placed at -18 ⁇ -25 ° C for 1-2 hours of rapid freezing;
  • step S30 the plant leaves treated after step S20 are placed at -6 Crush under vacuum and statically filter, take the filtrate as a plant stock solution, and set aside;
  • step S50 the health care liquid prepared in step S40 is filled, sterilized and packaged to obtain a manufactured product.
  • the plant stock solution in step S30 is a blueberry leaf extract or a blueberry leaf extract having a mass ratio of 1:1, and a ginkgo leaf extract.
  • the health care liquid of the present invention has a good mouthfeel and a simple preparation process. Regular consumption without any side effects, and significantly improve human immunity, increase human nutrition, strengthen the body, and delay aging.
  • the present invention provides a health care liquid capable of enhancing human immunity and anti-aging, characterized in that it comprises 30 ⁇ 3 ⁇ 4-60% of plant stock solution and 3%-8 ⁇ 3 ⁇ 4 of wine base based on mass percentage. , 0%-15 ⁇ 3 ⁇ 4 excipients
  • the rest is water.
  • the percentage by mass includes 40% of the plant stock solution, 5% of the wine base, 12% of the excipients, and the balance is water.
  • the auxiliary material is syrup and honey having a mass ratio of 5:3. Can be added as appropriate according to the needs of different tastes.
  • the syrup may be any one of sucrose syrup, fructose syrup, xylitol syrup or sucrose syrup, fructose syrup and xylitol syrup in a mass ratio of 1:1:; honey is refined honey.
  • the plant stock solution is a blueberry leaf extract.
  • the plant stock solution may be a blueberry leaf extract, a ginkgo leaf extract having a mass ratio of 1:1.
  • Blueberry scientific name bilberry Rhododendron bilberry.
  • the fruit is rich in nutrients, and the leaves also contain a variety of beneficial ingredients for the human body, which have a high health care effect.
  • beneficial ingredients for the human body, which have a high health care effect.
  • blueberry leaves also contain special ingredients such as flavonoids, catechins, proanthocyanidins, etc., which have good anti-brain nerve aging, strong heart and other health effects.
  • flavonoids have a variety of effects, are a strong antioxidant, can effectively remove oxygen free radicals in the body, prevent cell degradation and aging, effectively prevent cancer; improve blood circulation, reduce cardiovascular and cerebrovascular The incidence of disease, improve the symptoms of cardiovascular and cerebrovascular diseases; catechin is a general term for a class of highly active flavonoids, with cell regulation and antioxidant function; anthocyanins are hydroxyl donors, and homologous is also a kind Free radical scavenger. There is evidence that free radicals can cause oxidative damage to fats, proteins and nucleic acids and are important causes of diseases such as cancer, cardiovascular disease and neurological diseases. Anthocyanins bind to proteins to prevent peroxidation and thus play a very important role in the prevention of these diseases. Peer-to-peer enhances systemic immunity and reduces heart disease and stroke by preventing stress response and platelet aggregation caused by smoking.
  • Ginkgo biloba The leaves of Ginkgo biloba (also known as ginkgo) have important pharmaceutical value because they contain various pharmaceutical ingredients such as ginkgolides, ginkgolides, rutin, flavonoids and vitamin E.
  • the extract of Ginkgo biloba is a special medicine for treating cardiovascular diseases and anti-aging and anti-dementia.
  • the flavonoids effectively remove free radicals present in the body and inhibit the formation of lipid peroxides.
  • Grapes crushed, de-stalked, fermented, aged, from a variety of high-quality grapes (generally wine grapes) It is made by bottling and other processes.
  • the alcohol content is generally between 8.5 ° and 16.2 °.
  • Grapes are called antioxidant stars, and the grapes are rich in vitamins, minerals and flavonoids. Flavonoids are also powerful antioxidants that fight aging and remove free radicals from the body. Grape anesthesia and grape seed-rich anthocyanins are 18 times more potent than vitamin C. Grape-based wines also contain a variety of amino acids, minerals and vitamins. Long-term drinking can prevent heart disease, especially for cardiovascular diseases. At the same time, the anti-aging effect is obvious, and the human organs, skin and metabolic capacity are protected and improved to varying degrees.
  • the above-mentioned health care product capable of enhancing human immunity and anti-aging is prepared by the following method: [0031] S10, selecting a plant leaf that meets the requirements, and immersing 0.5_2 small sputum after cleaning;
  • step S10 the plant leaves treated in step S10 are frozen at -18 ⁇ -25 ° C for 1-2 hours;
  • the plant leaves treated by the step S20 is pulverized under a vacuum of -6 ° C and allowed to stand for filtration, and the filtrate is taken as a plant stock solution, and used;
  • the plant leaves treated by the step S20 are thoroughly pulverized under a vacuum of 0.092 MPa and a temperature of -6 ° C.
  • the filter area is 0.3m 2
  • the filter plate size is cp200mm
  • the number of filter plates is 11 pieces
  • the filter material is filter cloth with a pore size of 200 mesh
  • the microfiltration filter is used for fine filtration.
  • the filter plate is a microporous membrane, the membrane diameter is 0.45 ⁇ , and the filtrate is taken as a plant stock solution.
  • the configured health care liquid is homogenized by high pressure, and after vacuum degassing, at a temperature of 98 to 99 ° C, rapid instantaneous sterilization, the sterilization time is controlled in about 10 seconds. , the finished health care liquid.
  • the health care liquid prepared in step S40 is filled, sterilized and packaged to obtain a manufactured product.
  • the temperature of the feed liquid was maintained at 50 to 65 ° C., and filled with 25 ml each using a filling machine. Sterilization after filling, sterilization conditions are 70-75 ° C, 20-30 min, combined with filtration pore size 0.45 ⁇ sterilization before filling, can achieve the effect of controlling microbial indicators; finally packaged to get the factory products.
  • step S10 the blueberry leaves treated in step S10 are frozen at -25 ° C for 1 hour;
  • step S30 the blueberry leaves treated in step S20 are pulverized under vacuum conditions of -6 ° C and allowed to stand for filtration, and the filtrate is taken as a plant stock solution (blueberry stock solution), and used;
  • step S50 the health care liquid prepared in step S40 is filled, sterilized and packaged to obtain a manufactured product.
  • step S10 the blueberry leaves treated in step S10 are frozen at -20 ° C for 2 hours;
  • the blueberry leaves treated by the step S20 are pulverized under a vacuum condition of -6 ° C and allowed to stand for filtration, and the filtrate is taken as a plant stock solution (blueberry stock solution), and used;
  • the health care liquid prepared by the step S40 is filled, sterilized and packaged to obtain a factory product .
  • S20, the blueberry leaves and the ginkgo leaves treated in step S10 are respectively frozen at a temperature of -18 ° C for 1.2 hours;
  • S30, the blueberry leaves and the ginkgo leaves treated by the step S20 are respectively pulverized under vacuum conditions of -6 ° C and separately filtered, and the filtrate is taken as a plant stock solution (blueberry stock solution and ginkgo stock solution), respectively.
  • step S50 the health care liquid prepared in step S40 is filled, sterilized and packaged to obtain a manufactured product.
  • mice with the same growth state were taken, half male and half female.
  • Eighty white mice were randomly divided into four groups, each consisting of 10 female mice and 10 male mice.
  • the above four groups of mice were randomly labeled as the first group, the second group, the third group, and the control group; wherein, the first group, the second group, and the third group of mice were injected with the same doses as in the above Examples 1-3.
  • a health care solution that enhances immunity and anti-aging. Twice a day, 0.25ml each time. Continuous testing for 60 days.
  • the health care liquid of the present invention is composed of a plant leaf extract as a main raw material, and is composed of a wine base, syrup, honey and water. After raw materials processing, blending, homogenization, vacuum degassing, sterilization and other traditional processes, the process is simple and reasonable, often eat without any side effects, and significantly improve human immunity, increase human nutrition

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Abstract

一种增强人体免疫力、抗衰老的保健液，按质量百分比计算，包括30％-60％的植物原液、3％-8％的葡萄酒酒基、0％-15％的辅料，其余为水。所述植物原液为蓝莓叶提取物或质量比为1：1的蓝莓叶提取物、银杏叶提取物。所述保健液的制备方法包括：植物叶片清洗干净后浸泡0.5-2小时；置于-18～-25℃条件下速冻1-2小时；置于-6℃真空条件下粉碎并静置过滤，取滤液作为植物原液，备用；取设定比例范围内的原料混合均匀并瞬时杀菌，制得的保健液进行灌装、灭菌和包装。

Description

一种能增强人体免疫力、 抗衰老的保健液及其制备方法 技术领域
[0001] 本发明涉及保健品及制备方法领域， 特别涉及一种增强人体免疫力、 抗衰老的 保健液及制备方法。
背景技术
[0002] 免疫力是人体自身的防御机制， 通过细胞和体液免疫机制， 识别和消灭外来侵 入的异物（病毒、 细菌等）； 处理衰老、 损伤、 死亡、 变性的自身细胞； 识别和 处理体内突变细胞和病毒感染细胞。 它是机体对外界环境的适应能力、 抗邪能 力及康复能力。 随着年齢的增长， 机体的免疫功能发生不同程度的改变， 尤其 细胞免疫功能发生改变的程度更显著， 细胞免疫功能低下是导致衰老及多种疾 病的重要原因之一。
[0003] 随着人们生活水平的不断提高， 消费理念的日趋成熟， 对疾病和健康认识的不 断深入， 人们越来越重视通过食饮达到保健的目的， 对天然健康营养型食品的 需求越来越大， 功能性食品将成为我国食品工业研究发展的重要领域， 成为 21 世纪我国经济的重要增长点。
[0004] 与市场上常见的保健片剂相比， 保健液具有营养均衡、 吸收效果更好， 吸食便 禾 ij， 携带方便等特点而备受人们喜爱。 在现有技术中， 抗衰老、 增强人体免疫 力的保健液配方及制作工艺， 主要是对各种原料混合后在水中进行热提取， 虽 有一定的保健作用， 但由于工艺不合理， 具有保健作用的活性物质流失多， 有 效成分仅能摄取 20%左右， 效果不甚理想。 为此， 有待幵发效果更优的抗衰老、 增强免疫力的保健液， 满足人们现代生活的需要。
技术问题
[0005] 本发明的目的在于提供一种能增强人体免疫力、 抗衰老的保健液及其制备方法 问题的解决方案
技术解决方案 [0006] 本发明提出一种能增强人体免疫力、 抗衰老的保健液， 按质量百分比计算， 所 述保健液包括 30<¾-60<¾的植物原液、 3<¾-8<¾的葡萄酒酒基、 0<¾-15<¾的辅料， 其 余为水。
[0007] 优选地， 按质量百分比计算， 所述保健液包括 40%的植物原液、 5%的葡萄酒酒 基、 12 %的辅料， 其余为水。
[0008] 优选地， 所述植物原液为蓝莓叶提取物或质量比为 1:1的蓝莓叶提取物、 银杏 叶提取物。
[0009] 优选地， 所述辅料为质量比为 5:3的糖浆、 蜂蜜。
[0010] 优选地， 所述糖浆为质量比为 1:1 : 1的蔗糖糖浆、 果糖糖浆、 木糖醇糖浆或蔗 糖糖浆、 果糖糖浆和木糖醇糖浆中的任意一种。
[0011] 优选地， 所述蜂蜜为精炼蜂蜜。
[0012] 本发明还提出一种能增强人体免疫力、 抗衰老的保健液的制备方法， 其包括： [0013] S10， 选定符合要求的植物叶片， 清洗干净后浸泡 0.5_2小吋；
[0014] S20, 将经步骤 S10处理过的植物叶片置于 -18~ -25°C条件下速冻 1-2小吋； [0015] S30, 将经步骤 S20处理之后的植物叶片置于 -6°C真空条件下粉碎并静置过滤， 取滤液作为植物原液， 备用；
[0016] S40， 取设定比例范围内的植物原液、 葡萄酒酒基、 辅料加入纯净水至配置量
， 混合均匀并瞬吋杀菌， 制得保健液；
[0017] S50, 经步骤 S40制得的保健液进行灌装、 灭菌和包装， 得到出厂产品。
[0018] 优选地， 步骤 S30中所述植物原液为蓝莓叶提取物或质量比为 1:1的蓝莓叶提取 物、 银杏叶提取物。
发明的有益效果
有益效果
[0019] 本发明的保健液口感良好， 制备工艺简单。 经常食用无任何副作用， 并显著提 高人体免疫力， 增加人体营养， 强身健体， 延缓衰老。
实施该发明的最佳实施例
本发明的最佳实施方式
[0020] 应当理解， 此处所描述的具体实施例仅仅用以解释本发明， 并非用于限定本发 明的范围。
[0021] 本发明提出一种能增强人体免疫力、 抗衰老的保健液， 其特征在于， 按照质量 百分比计算， 包括 30<¾-60%的植物原液、 3%-8<¾的葡萄酒酒基、 0%-15<¾的辅料
， 其余为水。
[0022] 优选地， 按照质量百分比计算， 包括 40%的植物原液、 5%的葡萄酒酒基、 12 % 的辅料， 其余为水。
[0023] 本实施例中， 所述辅料为质量比为 5:3的糖浆、 蜂蜜。 可根据不同口味的需要 ， 酌情添加。 其中， 糖浆可为质量比为 1:1 : 1的蔗糖糖浆、 果糖糖浆、 木糖醇糖 浆或蔗糖糖浆、 果糖糖浆和木糖醇糖浆中的任意一种； 蜂蜜为精炼蜂蜜。
[0024] 本实施例中， 上述植物原液为蓝莓叶提取物。 在其它实施方式中， 植物原液可 以为质量比为 1:1的蓝莓叶提取物、 银杏叶提取物。
[0025] 蓝莓学名越桔， 杜鹃花科越桔属植物。 果实营养丰富， 叶片同样含有多种对人 体有益的成分， 具有很高的保健作用。 研究发现， 蓝莓叶中除含有常规的糖、 酸、 维生素 c、 矿物元素外， 还含有黄酮、 儿茶素、 原花青素等特殊成分， 具有 良好的防脑神经老化、 强心等保健作用。 其中， 黄酮具有多种功效， 是一种很 强的抗氧剂， 可有效清除体内的氧自由基， 同吋阻止细胞的退化、 衰老， 有效 防止癌症的发生； 改善血液循环， 降低心脑血管疾病的发病率， 改善心脑血管 疾病的症状； 儿茶素是一类具有高活性的类黄酮的总称， 具有细胞调节作用以 及抗氧化功能； 花青素是羟基供体， 同吋也是一种自由基清除剂。 已有证据表 明自由基可导致脂肪、 蛋白质和核酸的氧化损害， 是一些疾病如癌症、 心血管 疾病和神经性疾病的重要病因。 花青素能和蛋白质结合防止过氧化， 因而对这 些疾病的预防起到非常重要的作用。 同吋增强系统免疫能力， 并通过防止应激 反应和吸烟引起的血小板凝集来减少心脏病和中风的发生。
[0026] 银杏叶： 为银杏科植物银杏 （又称白果树） 的叶子， 因含有银杏内酯、 白果内 酯、 芸香素、 黄酮甙及维生素 E等多种药物成分而具有重要的药物价值。 银杏叶 的提取物是治疗心血管疾病和抗衰老、 抗痴呆特效药， 其中黄酮类化合物有效 地去除体内存在的自由基， 抑制过氧化脂质的形成。
[0027] 葡萄酒： 由各种优质葡萄 （一般为酿酒葡萄） 经过破碎、 除梗、 发酵、 陈酿、 装瓶等过程酿制而成， 酒精度一般在 8.5°到 16.2°之间。 葡萄堪称抗氧化明星， 葡 萄肉中富含丰富的维生素、 矿物质和类黄酮。 类黄酮也是一种强力抗氧化剂， 可抗衰老， 并可清除体内自由基。 葡萄皮和葡萄籽富含的花青素， 抗氧化的功 效比维生素 C高出 18倍之多。 而以葡萄为原料的葡萄酒也蕴藏多种氨基酸、 矿物 质和维生素， 长期饮用能够预防心脏病， 尤其对心血管疾病有突出的功效。 同 吋， 抗衰老功效明显， 对人体器官、 皮肤和代谢能力均有保护和不同程度的改 善作用。
[0028]
[0029] 制备方法：
[0030] 本发明提出的上述能增强人体免疫力、 抗衰老的保健品通过下述方法制成： [0031] S10， 选定符合要求的植物叶片， 清洗干净后浸泡 0.5_2小吋；
[0032] 在实际操作中， 采摘新鲜、 生长 90天以上植物叶片。 采摘后， 清洗干净并立刻 置于符合饮用水标准的无菌水浸泡 0.5_2小吋。 由于新鲜植物叶片含水率在 50% 以上， 浸泡 0.5— 2小吋后， 就可以让新鲜植物叶片含水率在 75%以上。
[0033] S20, 将经步骤 S10处理过的植物叶片置于 -18~ -25°C条件下速冻 1-2小吋；
[0034] 实际操作中， 浸泡吸水完后的植物叶片迅速送入速冻间进行速冻， -25°C条件 下速冻 2小吋。
[0035] S30, 将经步骤 S20处理之后的植物叶片置于 -6°C真空条件下粉碎并静置过滤， 取滤液作为植物原液， 备用；
[0036] 将经步骤 S20处理之后的植物叶片置于真空度 0.092MPa， 温度 -6°C下彻底粉碎
， 保护植物速冻叶不解冻氧化， 最大程度保护活性成分不损失； 静置 24小吋后
， 先用板框压滤机粗滤， 过滤面积为 0.3m2， 滤板尺寸为 cp200mm， 滤板数量为 11 片， 滤材为孔径 200目的滤布， 再用微孔滤膜过滤器精滤， 滤板为微孔滤膜， 滤 膜直径 0.45μηι， 取滤液作为植物原液。
[0037] S40, 取设定比例范围内的植物原液、 葡萄酒酒基、 辅料加入纯净水至配置量
， 混合均匀并瞬吋杀菌， 制得保健液；
[0038] 具体操作中， 配置好的保健液经高压匀质化， 并在真空脱气后， 在 98至 99°C的 温度条件下， 快速瞬吋杀菌， 杀菌吋间控制在 10秒钟左右， 制得成品保健液。 [0039] S50， 经步骤 S40制得的保健液进行灌装、 灭菌和包装， 得到出厂产品。
[0040] 保持料液温度在 50至 65°C吋， 用灌装机按每支 25ml灌装。 灌装后灭菌， 灭菌条 件为 70-75°C， 20-30min, 配合灌装前过滤孔径 0.45μηι除菌， 可达到控制微生物 指标的效果； 最后包装得到出厂产品。
[0041] 其中， 本实施例中， 真空脱气、 灌装、 灭菌工艺为现有技术， 故不赘述。
[0042] 实施例 1
[0043] S10， 选定符合要求的蓝莓叶片， 清洗干净后浸泡 2小吋；
[0044] S20, 将经步骤 S10处理过的蓝莓叶片置于 -25°C条件下速冻 1小吋；
[0045] S30, 将经步骤 S20处理之后的蓝莓叶片置于 -6°C真空条件下粉碎并静置过滤， 取滤液作为植物原液 （蓝莓原液） ， 备用；
[0046] S40, 按以下重量取下述各组分： 30g植物原液、 8g葡萄酒酒基、 3.1g蔗糖糖浆
、 3.1g果糖糖浆、 3.1g木糖醇糖浆、 5.7g精炼蜂蜜， 然后加入纯净水至 100g， 混 合均匀并瞬吋杀菌， 制得保健液；
[0047] S50, 经步骤 S40制得的保健液进行灌装、 灭菌和包装， 得到出厂产品。
[0048]
[0049] 实施例 2
[0050] S10， 选定符合要求的蓝莓叶片， 清洗干净后浸泡 0.5小吋；
[0051] S20, 将经步骤 S10处理过的蓝莓叶片置于 -20°C条件下速冻 2小吋；
[0052] S30, 将经步骤 S20处理之后的蓝莓叶片置于 -6°C真空条件下粉碎并静置过滤， 取滤液作为植物原液 （蓝莓原液） ， 备用；
[0053] S40, 按以下重量取下述各组分： 40g植物原液、 5g葡萄酒酒基、 7.5g蔗糖糖浆
、 4.5g精炼蜂蜜， 然后加入纯净水至 100g， 混合均匀并瞬吋杀菌， 制得保健液； [0054] S50, 经步骤 S40制得的保健液进行灌装、 灭菌和包装， 得到出厂产品。
[0055]
[0056] 实施例 3
[0057] S10， 选定符合要求的蓝莓叶片和银杏叶片， 清洗干净后浸泡 1.5小吋；
[0058] S20, 将经步骤 S10处理过的蓝莓叶片和银杏叶片分别置于 -18°C条件下速冻 1.2 小吋； [0059] S30， 将经步骤 S20处理之后的蓝莓叶片和银杏叶片分别置于 -6°C真空条件下粉 碎并分别静置过滤， 分别取滤液作为植物原液 （蓝莓原液和银杏原液） ， 备用
[0060] S40, 按以下重量取下述各组分： 30g蓝莓原液、 30g银杏原液、 3g葡萄酒酒基
， 然后加入纯净水至 100g， 混合均匀并瞬吋杀菌， 制得保健液；
[0061] S50, 经步骤 S40制得的保健液进行灌装、 灭菌和包装， 得到出厂产品。
[0062]
[0063] 功效与用途： 抗疲劳、 增强免疫力
[0064] 使用人群： 成年人
[0065] 用法和用量： 每日两次， 每次一支 （25ml) ， 饭前、 饭后均可服用， 无禁忌。
[0066] 现将本发明实施案例 1-3中制备的能增强人体免疫力、 抗衰老的保健液在小白 鼠身上进行试验。
[0067] 取生长状态一致的小白鼠 80只， 雌雄各半。 80只小白鼠随机平均分成 4组， 每 一组包括 10只雌性小白鼠和 10只雄性小白鼠。 上述 4组小白鼠随机被标记为第一 组、 第二组、 第三组及对照组； 其中， 第一组、 第二组、 第三组小白鼠同等剂 量分别注射上述实施例 1-3制成的能增强免疫力、 抗衰老的保健液。 每天两次， 每次 0.25ml。 持续试验 60天。
[0068]
[0069] 实验结果如下表所示 （表 2)
Figure imgf000007_0001
[0070] 由上述表格数据可知: 本发明的增强人体免疫力、 抗衰老的保健液通过蓝莓叶 提取物、 银杏叶提取物、 葡萄酒酒基及糖浆、 蜂蜜的特性及功效, 对人体的抗 氧化能力、 血糖血清及免疫力均有改善明显改善。
[0071] 本发明保健液， 由植物叶片提取液为主要原料， 配以葡萄酒酒基、 糖浆、 蜂蜜 及水组成。 经过原料处理， 调配、 匀质、 真空脱气、 杀菌等传统工序完成， 工 艺简单合理， 经常食用无任何副作用， 并显著提高人体免疫力， 增加人体营养
， 强身健体， 延缓衰老。
[0072] 以上所述仅为本发明的较佳实施例， 并不用以限制本发明， 凡在本发明的精 神和原则之内， 所作的任何修改、 等同替换、 改进等， 均应包含在本发明的保 护范围之内。
[0073]

Claims

权利要求书
[权利要求 1] 一种能增强人体免疫力、 抗衰老的保健液， 其特征在于， 按质量百分 比计算， 包括 30<¾-60<¾的植物原液、 3<¾-8<¾的葡萄酒酒基、 0<¾-15<¾ 的辅料， 其余为水。
[权利要求 2] 如权利要求 1所述的能增强人体免疫力、 抗衰老的保健液， 其特征在 于， 按质量百分比计算， 包括 40%的植物原液、 5%的葡萄酒酒基、 1
2 %的辅料， 其余为水。
[权利要求 3] 如权利要求 1或 2所述的能增强人体免疫力、 抗衰老的保健液， 其特征 在于， 所述植物原液为蓝莓叶提取物或质量比为 1: 1的蓝莓叶提取物
、 银杏叶提取物。
[权利要求 4] 如权利要求 1所述的能增强人体免疫力、 抗衰老的保健液， 其特征在 于， 所述辅料为质量比为 5:3的糖浆、 蜂蜜。
[权利要求 5] 如权利要求 4所述的能增强人体免疫力、 抗衰老的保健液， 其特征在 于， 所述糖浆为质量比为 1: 1 : 1的蔗糖糖浆、 果糖糖浆、 木糖醇糖浆 或蔗糖糖浆、 果糖糖浆和木糖醇糖浆中的任意一种。
[权利要求 6] 如权利要求 4所述的能增强人体免疫力、 抗衰老的保健液， 其特征在 于， 所述蜂蜜为精炼蜂蜜。
[权利要求 7] —种能增强人体免疫力、 抗衰老的保健液的制备方法， 用于制备上述 权利要求 1至 6中任一项所述的保健液， 其特征在于， 包括以下步骤： S10， 选定符合要求的植物叶片， 清洗干净后浸泡 0.5_2小吋； S20， 将经步骤 S10处理过的植物叶片置于 -18~ -25°C条件下速冻 1-2小 吋；
S30, 将经步骤 S20处理之后的植物叶片置于 -6°C真空条件下粉碎并静 置过滤， 取滤液作为植物原液， 备用；
S40， 取设定比例范围内的植物原液、 葡萄酒酒基、 辅料加入纯净水 至配置量， 混合均匀并瞬吋杀菌， 制得保健液；
S50， 经步骤 S40制得的保健液进行灌装、 灭菌和包装， 得到出厂产 [权利要求 8] 如权利要求 7所述的能增强人体免疫力、 抗衰老的保健液的制备方法
， 其特征在于， 步骤 S30中所述植物原液为蓝莓叶提取物或质量比为 1 : 1的蓝莓叶提取物、 银杏叶提取物。
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