WO2017061031A1 - 動物の運動量測定方法 - Google Patents
動物の運動量測定方法 Download PDFInfo
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- WO2017061031A1 WO2017061031A1 PCT/JP2015/078759 JP2015078759W WO2017061031A1 WO 2017061031 A1 WO2017061031 A1 WO 2017061031A1 JP 2015078759 W JP2015078759 W JP 2015078759W WO 2017061031 A1 WO2017061031 A1 WO 2017061031A1
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- 241001465754 Metazoa Species 0.000 title claims abstract description 88
- 238000000034 method Methods 0.000 title claims abstract description 49
- 238000005303 weighing Methods 0.000 claims description 49
- 238000009395 breeding Methods 0.000 claims description 22
- 230000001488 breeding effect Effects 0.000 claims description 22
- 238000005259 measurement Methods 0.000 claims description 22
- 238000002474 experimental method Methods 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 230000002093 peripheral effect Effects 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 4
- 238000012935 Averaging Methods 0.000 description 3
- 230000037396 body weight Effects 0.000 description 3
- 230000000384 rearing effect Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000007423 decrease Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000004584 weight gain Effects 0.000 description 2
- 235000019786 weight gain Nutrition 0.000 description 2
- 208000024780 Urticaria Diseases 0.000 description 1
- 238000003975 animal breeding Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 230000000422 nocturnal effect Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1126—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb using a particular sensing technique
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
- A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K29/00—Other apparatus for animal husbandry
- A01K29/005—Monitoring or measuring activity, e.g. detecting heat or mating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01G—WEIGHING
- G01G17/00—Apparatus for or methods of weighing material of special form or property
- G01G17/08—Apparatus for or methods of weighing material of special form or property for weighing livestock
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01G—WEIGHING
- G01G19/00—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups
- G01G19/40—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups with provisions for indicating, recording, or computing price or other quantities dependent on the weight
- G01G19/413—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups with provisions for indicating, recording, or computing price or other quantities dependent on the weight using electromechanical or electronic computing means
- G01G19/414—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups with provisions for indicating, recording, or computing price or other quantities dependent on the weight using electromechanical or electronic computing means using electronic computing means only
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/40—Animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/42—Evaluating a particular growth phase or type of persons or animals for laboratory research
Definitions
- the present invention relates to a method of measuring the amount of exercise of animals in animal experiments and the like.
- Patent Document 1 An optical method in which a light path is defined, a light emitting element and a light receiving element are arranged, and the number of times an animal passes through the light path is measured (Patent Document 1).
- Patent Document 2 A method of photographing the entire cage for rearing animals with a CCD camera and measuring the number of times the animals entered each area set in the cage: (Patent Document 2), (3) A method of attaching a RFID tag to an animal and measuring a movement trajectory based on position information of an RFID reader (Patent Document 3)
- Patent Document 3 A method of placing a rotating cage in a cage and measuring the number of rotations of the rotating cage, Etc. are well known.
- JP-A-7-184515 Japanese Patent Application Laid-Open No. 8-32959 JP 2002-58648 A JP-A-6-133956
- the data obtained by the above methods (1) to (4) are digital counts such as the number of times the animals come and go and the number of rotations of the cage, and it is difficult to consider the physical quantity that the counts represent.
- the data obtained is the measurement value of the measurement table, food and water loss may affect the amount of exercise, and the weight of the animal increases with age. At the same time, even if the movement is the same, the change in the measured value becomes larger after weight gain, and there is a problem that the amount of exercise is greatly evaluated.
- An object of the present invention is to solve the above-mentioned problems and to provide a new method of measuring the amount of exercise of an animal.
- the method for measuring the amount of exercise of animals continuously measures the weighing values of the animals to be measured with a weighing instrument, and uses the weighing values obtained in time series. The amount of change is calculated, and the amount of exercise of the animal is measured by dividing the amount of change of the measured value and the weight of the animal.
- the measured value of the animal to be measured is continuously measured with a meter, a predetermined exercise amount calculation interval is set, and the latest measured value and its previous time
- the difference with the measured value of is calculated, the integrated value obtained by integrating the absolute value of the difference is calculated, and for each exercise amount calculation interval, the integrated value is the average value of the weight of the animal in the exercise amount calculation interval or the exercise amount calculation interval
- a value divided by the weight of the animal at one time point is calculated and defined as the amount of exercise of the animal.
- the time at which the momentum is calculated be one axis and the momentum be another axis to visualize and output the momentum.
- the weight of the animal is determined by the difference between the weighing value when it is determined that the animal has got on the weighing plate of the weighing scale and the weighing value when it is determined that the animal has fallen from the weighing plate. Is also preferred.
- the present invention using a meter which continuously measures the measured value, the value of which unit is made dimensionless by dividing the amount of change of the measured value and the weight of the animal calculated from the measured value Newly defined as In this way, it is possible to eliminate the difference in weight between individuals in the living body and in the growth process, and to measure the amount of exercise of the animal based on the change in the weight of the living body.
- FIG. 1 It is a structure block diagram of the exercise amount measuring system of the animal which concerns on embodiment.
- Figure 2 is a right side view of the animal scale used in the system of Figure 1; It is a flowchart of the exercise amount measuring method of the animal which concerns on embodiment. It is a flowchart of the measuring method of the weight in the flowchart of FIG. It is the graph which visualized the momentum obtained by the embodiment. It is the graph which visualized the momentum obtained by the embodiment. It is a figure which shows the difference of the momentum obtained by embodiment and the momentum obtained by the comparative example.
- the exercise amount measuring system 1 for animals of the present embodiment (hereinafter, referred to simply as the system 1) has an animal weight scale 2 and an analysis device 3.
- the animal weight scale 2 suitable for the present system 1 as described below, the weighing dish 27 is disposed in the breeding container 22 (in the breeding space 20), and the mass sensor 25 is disposed outside the breeding space 20. .
- the animal weight scale 2 includes a weighing scale 21 (balance), a breeding container 22 (breeding cage), a support case 23, and a wireless transmitter 24.
- the weighing device 21 is shown in cross section so that the configuration of the arrangement of the weighing plate 27 can be understood.
- the weighing device 21 has a main body case 26 containing a mass sensor 25, a weighing plate 27, a plate support 28, and a peripheral wall 29.
- the mass sensor 25 may employ an electromagnetic balance type, a strain gauge type, a capacitance type, or the like, and acquires measurement data of the one placed on the weighing pan 27. Instead of the weighing tray 27, exercise equipment for animals or hives for resting can be used.
- the mass sensor 25 may be appropriately selected according to the weight capacity and the minimum display (reading accuracy of the measured value) according to the weight of the animal to be experimented, and the strength performance.
- the pan support 28 is a hollow member that connects the weighing pan 27 and the mass sensor 25, is fixed to the mass sensor 25, and extends vertically upward from the mass sensor 25.
- the dish support 28 has a required length (height) for projecting the weighing dish 27 into the breeding container 22.
- the peripheral wall portion 29 includes a hollow portion surrounding the plate support 28 projecting from the main body case 26 in the circumferential direction and its base portion, and is fixed to the upper surface of the main body case 26.
- the animals are reared in the rearing container 22 (rearing space 20).
- a bottom opening 30 is formed to allow the plate support 28 and the peripheral wall 29 to pass through.
- a diaphragm 31 for eliminating a gap is disposed between the peripheral wall 29 and the bottom opening 30.
- the breeding container 22 is supported downward by the support case 23.
- the support case 23 has an opening at the front, from which the meter 21 can be operated.
- a case hole 32 for passing the plate support 28 and the peripheral wall 29 is formed on the upper surface of the support case 23.
- the breeding container 22 is positioned by the peripheral wall portion 29, and the entire weight of the breeding container 22 is supported by the support case 23. For this reason, the weight of the breeding container 22 itself as well as the weight of food, water, other breeding paper and the like are all received by the support case 23, and the weight other than that placed on the weighing plate 27 is not weighed by the weighing device 21.
- a wireless transmitter 24 is installed in the support case 23.
- the weighing data detected by the mass sensor 25 is converted into a weighing value by the CPU in the weighing device 21 and output to the wireless transmitter 24 via the RS-232C cable, and a wireless receiver 45 on the analysis device 3 side described later. Received by
- the mass sensor 25 may also be disposed in the breeding space 20. The details of this embodiment are described in International Application No. PCT / JP2015 / 62508 filed by the present applicant.
- the analysis device 3 is a PC (personal computer) or the like, and an analysis unit 41 having a CPU, a ROM, a RAM, etc., a storage unit 42 such as a magnetic hard disk or semiconductor memory, a display unit 43, a key switch unit 44, etc. It may be a general purpose one.
- the experimenter can perform various operations from the key switch unit 44, and can confirm various operations and analysis results on the display unit 43.
- a wireless receiver 45 is connected to the analysis device 3.
- the signal of the weighing value received by the wireless receiver 45 is continuously recorded in the storage unit 42 in association with the time.
- the storage unit 42 stores various programs for performing flowchart processing to be described later, and the analysis unit 41 executes the programs.
- the “weight value” is the weight data obtained by converting the weight data acquired by the mass sensor 25 (raw data), and the “weight” is It means “weight value” determined in the flowchart of FIG. 4 described later.
- an exercise amount calculation interval t (hereinafter, simply referred to as a calculation interval) for calculating an exercise amount is arbitrarily set from the key switch unit 44.
- the calculation interval t is preferably, for example, one hour for continuous measurement for several weeks, 30 minutes for continuous measurement for several days, or 10 minutes for continuous measurement for several hours.
- step S2 the process proceeds to step S2, where the measured value D n-1 (n indicates the number of times of sampling) measured by the weighing pan 27 is received.
- step S3 the process proceeds to step S3, and the weighing value D n measured by the weighing pan 27 is received. Acquisition of a measurement value samples about 10 times in 1 second, for example.
- step S5 it is determined whether the calculation interval t has elapsed.
- step S6 the value of D n is substituted for D n ⁇ 1 , and the process returns to step S3 to repeat integration. If the calculation interval t has passed, the process proceeds to step S7, and the average weight W of the animal at the calculation interval t is determined. The method of determining the weight used in step S7 will be described later.
- step S9 the date and time and the amount of exercise obtained in step S8 are displayed on the display unit 43, and the integration value S is reset to zero.
- step S10 it is determined whether to repeat the measurement. When continuing, it transfers to step S6 and repeats the calculation of the amount of movement. If it does not continue, the measurement ends.
- the average weight of the weight obtained over the entire time of the set calculation interval t is calculated in step S7, and the integrated value S divided by the average weight W is the amount of exercise in step S8.
- the average weight W (A) an average value of weight obtained over part of the calculation interval t, or (B) a weight at any one of the calculation intervals t is used. It is also good. Specifically, in the case of (A), if the calculation interval t is 24 hours, the average value Wp of the weight obtained from the last time to one hour before is determined in step S7, and the integrated value S is calculated as this weight
- the value divided by the average Wp may be defined as momentum.
- step S7 the weight w at the time when the calculation interval t has elapsed may be acquired, and the integrated value S may be defined as the value divided by the weight w as the amount of exercise. In either case, the calculation time of step S7 can be shortened.
- the weight of the animal is calculated in step S7, and this weight is the difference between the measured value when it is determined that the animal has got on the measuring plate 27 and the measured value when it is determined that the animal has got off the measuring plate 27. Determine.
- step S101 the analysis device 3 determines whether the sampled metric value D n is within the range of the threshold A. If it is not within the range of the threshold A (No), the next measured value is received. If it is within the range of the threshold A (Yes), the process proceeds to step S102.
- step S102 the measurement value D n in step S101 is set as the measurement average Wa, and the number of times of averaging is set to 1, and the process proceeds to step S103.
- the process proceeds to step S104.
- step S104 it is determined whether the metric value D n + 1 in step S103 is equal to or less than a threshold B (B ⁇ A). If it is less than or equal to the threshold B (Yes), the process proceeds to step S105. If the threshold value B is exceeded (No), the process proceeds to step S109.
- step S105 it is determined whether the measured value D n in step S103 is about the same as the previous measured value D n-1 (for example, within the previous measured value ⁇ 0.01 g). If the degree is the same (Yes), the process proceeds to step S106, the zero number is incremented by 1, ie, the number of times of coincidence is counted up, and the process proceeds to step S106. If the degree is not the same (No), the process proceeds to step S107, where the number of times of zero is zero, ie, the number of times of coincidence is reset, and the process returns to step S103.
- step S108 it is determined whether the number of times of zero counted in step S106 is equal to or greater than a prescribed number of times (for a predetermined time, for example, 2 seconds). If it is less than the prescribed number (No), the process returns to step S103. If it is the specified number or more (Yes), the process proceeds to step S111.
- a prescribed number of times for a predetermined time, for example, 2 seconds.
- step S109 it is judged whether the measured value Dn + 1 is in the range of the threshold value A again. If it is not within the range of the threshold A (No), the process returns to step S103. If it is within the range of the threshold A (Yes), the process proceeds to step S110.
- step S110 if the difference between the measured value D n + 1 and the measured average Wa is equal to or less than a predetermined stability width C (for example, 2% of Wa), the measured value W is added to update the measured average Wa, and the averaging number is updated. Make +1. Then, the measurement average Wa and the number of times of averaging at this time are updated, and the process returns to step S103.
- a predetermined stability width C for example, 2% of Wa
- step S111 the measured value that matches the specified number of times or more in step S108 is updated as a new zero point Z. Then, using the measured average Wa obtained in step S110 and the updated zero point Z, the difference between the measured average Wa and the zero point Z is calculated, and this value is determined as a weight value and stored together with the time.
- the determination of "the animal has got on the weighing pan 27" sets the threshold A (full-side threshold), and when the state where the measured value is the threshold A or more continues for a predetermined time (for example, 1 second or more) It is determined that Although the threshold A is set based on the known weight of the animal, such as a value estimated from weight measurement before the experiment or a value approximately grasped by multiple measurements immediately after the start of the experiment, the experiment starts After a plurality of measured values are obtained, the threshold A is updated with time based on the average.
- the threshold A is set to an upper limit and a lower limit by an average value ⁇ ⁇ % of body weight (for example, ⁇ 2% to ⁇ 10% of the average), and a state where the upper limit and the lower limit are exceeded. Let's determine that we got on. Thereby, the center of gravity swing of the animal can be allowed.
- the determination that "the animal has fallen from the weighing pan 27" basically comes down when the state where the measured value is less than the threshold A (or less than the lower limit A2) continues for a predetermined time (for example, 1 second or more) Determine.
- the threshold B zero-side threshold
- the threshold B may be set based on the stable weighing value on the zero side to determine that the animal is lowered. In other words, if it is determined that the condition is below threshold B for a certain period of time, it is determined that the animal has fallen by half, or the tail is touching the breeding container 22, etc. It is possible to prevent erroneous measurement when the measured value becomes stable.
- FIG. 5 and FIG. 6 are the suitable examples which visualized and output the momentum obtained in this way, and are examples of what was output by step S9 of FIG.
- FIG. 5 shows the results of measurement of a mouse with an initial weight of 25.0 g over 13 days according to the flowcharts of FIG. 3 and FIG. 4, where the horizontal axis is time [day] and the left vertical axis is weight [g], The right vertical axis shows the amount of exercise [-].
- the measurement value was continuously measured as once every 0.1 second and the calculation interval t of the momentum was 24 hours. It was confirmed that this system 1 can quantitatively measure the amount of exercise of the animal.
- FIG. 6 shows the results of measuring a mouse having an initial weight of 25.0 g for 12 days according to the flowcharts of FIG. 3 and FIG. 4 and switching the light / dark of the breeding room every half day to measure the exercise amount;
- the horizontal axis represents time [day]
- the left vertical axis represents weight [g]
- the right vertical axis represents exercise amount [-].
- the measurement value was measured once every 0.1 second, and the calculation interval t of the momentum was measured as 12 hours.
- the uncolored bar graph is bright, the colored bar graph is dark. Because the mouse is nocturnal, the amount of exercise is greater when it is dark. This system 1 has been able to quantitatively confirm such changes in the amount of exercise due to the environment.
- FIG. 7 compares the graph of FIG. 5 (FIG. 7 lower) with the comparative example (FIG. 7 upper).
- the comparative example (FIG. 7 upper) uses the same measured value as the measured value used for the graph of FIG. 5, but does not divide the sum of changes in measured value by the weight (that is, step S1 to FIG. 3) It is the graph which performed to S4 and made the integral value S of step S4 the amount of exercise, and output the value which does not divide "the integral value S by the weight value" of steps S7 and S8.
- the amount of exercise of the animal can be measured by a novel method, and not only day and night, external stimuli such as light and sound, factors such as gender, age, genetics, and drugs It is possible to quantitatively measure the influence on exercise amount by the administration of poisons and the like.
- the exercise amount is calculated using the measurement value fluctuation associated with the activity of each living body and the weight of the living body at that time. It becomes possible to compare. Moreover, since the momentum obtained in this way is visualized and output, comparison, analysis, etc. can be easily performed.
- the weight used for calculating the amount of exercise is determined by the difference between the weighing value when the animal gets on and off the weighing plate. Even if foreign matter such as water or food is placed on the measuring plate to change the breeding environment, it is preferable because an exercise amount using the value obtained by subtracting the influence is obtained at any time. As a result, the amount of exercise can be measured with high accuracy over a long time and a long time.
- the method for measuring the amount of exercise of animals uses a conventional form of balance even if the weighing dish is not disposed in the breeding container, even if it has a configuration other than the animal weight scale 2 used in the embodiment.
- the amount of exercise can also be determined using the obtained metric value.
- the body weight is obtained by a method other than the method for measuring the weight of the animal used in the embodiment, that is, the body weight is obtained by taking the animal out of the breeding container and placing it on a measuring plate as in the conventional case. You can also use it to determine the amount of exercise.
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Abstract
Description
(1)光の通路を定めて発光素子および受光素子を配置し、その光路を動物が通過した回数を計測する光学式(特許文献1)、
(2)CCDカメラによって動物を飼育するケージ全体を撮影し、ケージ内に設定した各エリアに動物が入った回数を計測する方式:(特許文献2)、
(3)動物にRFIDタグを取りつけRFIDリーダの位置情報に基づいて移動軌跡を測定する方式(特許文献3)、
(4)ケージ内に回転かごを入れ、回転かごの回転数を計測する方式、
等がよく知られている。
(5)この他に、動物を天秤の測定台に載せ、この計量値を設定時間取得し、予め測定した前記動物の静荷重と前記計量値との差の絶対値を時間積算し、この積算値を動物の活動量とする手法がある(特許文献4)。
(システムの構成)
図1に示すように、本形態の動物の運動量測定システム1(以下、単にシステム1とする)は、動物用体重計2と、解析装置3を有する。本システム1に好適な動物用体重計2は、以下のように、計量皿27が飼育容器22内(飼育空間20内)に配置され、質量センサ25は飼育空間20の外に配置されている。
次に、本システム1で行われる動物の運動量測定方法を、図3のフローチャートに基づき説明する。以後の説明で誤解が生じないように定義すると、「計量値」とは、質量センサ25で取得された計量データが計量値に変換されたもの(生データ)であり、「体重」とは、後述する図4のフローチャートで確定される「体重値」を意味する。
2 動物用体重計
3 解析装置
21 計量器
22 飼育容器
27 計量皿
41 解析部
43 表示部
Claims (5)
- 被測定対象となる動物の計量値を計量器で連続的に測定し、時系列で得られた前記計量値の変化量を算出し、前記計量値の変化量と前記動物の体重との除算から、動物の運動量を測定することを特徴とする動物の運動量測定方法。
- 被測定対象となる動物の計量値を計量器で連続的に測定し、
所定の運動量算出間隔を設定し、
最新の計量値とその1回前の計量値との差分を計算し、
前記差分の絶対値を積算した積算値を算出し、
前記運動量算出間隔毎に、前記積算値を運動量算出間隔における動物の体重の平均値または運動量算出間隔における一の時点での動物の体重で割った値を算出し動物の運動量として定義することを特徴とする動物の運動量測定方法。 - 前記運動量が算出された時間を一方の軸にとり、前記運動量を他の軸にとり、前記運動量を可視化して出力することを特徴とする請求項1に記載の動物の運動量測定方法。
- 前記計量値は、動物の飼育容器内に前記計量器の計量皿を配置した形態で取得されたものを使用することを特徴とする請求項1に記載の動物の運動量測定方法。
- 前記動物の体重は、前記計量器の計量皿に動物が乗ったと判別された時の計量値と前記計量皿から動物が降りたと判別された時の計量値との差で確定されることを特徴とする請求項1に記載の動物の運動量測定方法。
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US15/754,619 US20180242889A1 (en) | 2015-10-09 | 2015-10-09 | Method for measuring amount of movement of animal |
PCT/JP2015/078759 WO2017061031A1 (ja) | 2015-10-09 | 2015-10-09 | 動物の運動量測定方法 |
JP2017544154A JP6579671B2 (ja) | 2015-10-09 | 2015-10-09 | 動物の運動量測定方法 |
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CN113834554A (zh) * | 2021-11-24 | 2021-12-24 | 深圳净拓生物科技有限公司 | 一种实验小鼠连续变化称重装置及其使用方法 |
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WO2017136896A1 (en) * | 2016-02-11 | 2017-08-17 | Somark Group Limited | A system and a method for ascertaining the mass of at least one animal |
DE202016105709U1 (de) * | 2016-10-12 | 2018-01-15 | Big Dutchman International Gmbh | Wiegemodul für ein Nest in einer Geflügeltierhaltung und Nest |
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