WO2013086868A1 - Endoprothèse endoluminale recyclable structurale hybride - Google Patents

Endoprothèse endoluminale recyclable structurale hybride Download PDF

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Publication number
WO2013086868A1
WO2013086868A1 PCT/CN2012/080375 CN2012080375W WO2013086868A1 WO 2013086868 A1 WO2013086868 A1 WO 2013086868A1 CN 2012080375 W CN2012080375 W CN 2012080375W WO 2013086868 A1 WO2013086868 A1 WO 2013086868A1
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WO
WIPO (PCT)
Prior art keywords
stent
end portion
hybrid
recovery
wire
Prior art date
Application number
PCT/CN2012/080375
Other languages
English (en)
Chinese (zh)
Inventor
陈晓丹
陈美娟
李玉茜
冷德嵘
Original Assignee
南京微创医学科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 南京微创医学科技有限公司 filed Critical 南京微创医学科技有限公司
Publication of WO2013086868A1 publication Critical patent/WO2013086868A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure

Definitions

  • This invention relates to a medical device, and more particularly to a stent for use in dilatation to treat a stenotic or obstructive lesion, and more particularly to a hybrid structural intraluminal retrievable stent. Background technique
  • the therapy is a method of using a catheter to deliver a drug or surgical device to a lesion for treatment.
  • the introduction of a highly elastic mesh stent is one of the important applications.
  • the stents in the non-vascular lumen are mainly hand-woven diamond-shaped mesh stents.
  • the bending performance is not ideal, the radial support force is insufficient, and the axial shortening rate is large after implantation. More complications, and serious problems lead to secondary surgery. At the same time, the problem of recyclability of such stents has been plagued.
  • the stent cannot be recovered after being implanted into the human body. Once the stent is placed improperly or the patient's complications are serious, the stent cannot be removed safely and effectively in time, which will result in a serious medical accident. Therefore, the requirements for recyclability of the stent are clinically required, and the requirement for the implantation period of the stent in the human body also requires the recyclability of the stent, otherwise tissue proliferation occurs in the human body, and the silk material is broken due to corrosion and causes the official cavity. Serious consequences such as perforation and bleeding.
  • the most retrievable aspect of the stent is threading in the mesh at the head end, but since the mesh is parallel to the surface of the stent, the friction between the wire and the wire is large when pulling the wire, so The pulling force is also large, and the head end shrinkage is not in place and the line is broken, which makes the bracket difficult to recycle, or the head end portion is not flattened when the wire is pulled, and the wall of the lumen is stimulated during the recovery process.
  • the object of the present invention is to design a recyclable stent in a mixed structure lumen with convenient recovery and good radial strength in view of the problems of low radial strength and inconvenient recovery in the existing intraluminal stent.
  • a hybrid structure intracavity retrievable stent which is composed of a cylinder main body 2 and an end portion 3 connected at both ends thereof, characterized in that the cylindrical portion 2 has a scaly structure, and the scaly structure is woven.
  • the formed structure, the two ends 3 At least one end portion 3 is provided with at least one annular structure 4, and the annular structure 4 is provided with a recovery wire 5, and the joint of the recovery wire 5 is knotted to form a node 7.
  • the end portion 3 and the cylindrical portion 2 are of a unitary structure or a separate structure. When the end portion 3 is a split structure, it is connected to the column portion 2 by welding, soft wire or film.
  • the number of the recovery wires 5 is one or more, and the number of the nodes is equal to the number of the recovery wires 5.
  • the two end portions 3 have the same structure of a bell mouth, a ball head, a cup mouth shape or any two.
  • the inner surface and/or the outer surface of the column body 2 and the end portion 3 are partially or entirely provided with a coating film, and the coating material is a polymer material having good biocompatibility.
  • the annular structure 4 of the end portion 3 is an annular structure having a rotation angle formed by winding a wire, and the annular structure 4 is wound into one or more turns.
  • the hybrid structural support of the present invention is processed from a wire having good biocompatibility, and is composed entirely of two ends and an intermediate portion.
  • the middle portion and the end portions can be mixed by hand weaving and mechanical weaving, and can be selected as needed.
  • the middle part is woven by weaving, the stent has good compliance while enhancing the radial support strength of the whole stent.
  • the special scaly mesh structure reduces the stimulation of the stent wall to the lumen.
  • the axial shortening rate makes positioning more accurate.
  • the head end is composed of a ring structure with a certain rotation angle formed by winding the wire material, and the ring structure can be wound into a plurality of shapes by the wire material, and can be wound one turn or Multiple turns, in the ring structure, one or more wires with sufficient strength can be passed through, and knotted at the joint of the wire, the number of knots can be one or more, according to the actual situation, a reasonable choice, and The change in shape at both ends provides more selectivity.
  • the invention solves the defects of the conventional stent, and has the advantages of simple and novel structure, high success rate of surgery, small pain of the patient, good curative effect, and the like, and has broad prospects in clinical application.
  • the head end recyclable structure of the present invention allows each mesh of the head end portion to be easily contracted together during recovery, and has a regular structure, thereby avoiding the stimulation of the lumen wall at the end of the stent head during recovery, and reducing
  • the angular design of the annular structure reduces the friction between the wire and the wire, improving the safety of the recyclable stent.
  • the design of the multi-junction of the recycling line improves the success rate of recyclability and the convenience of operation, so that the stent can ensure its own recyclability while treating the lesion, and prevent the stent from being implanted for too long or difficult to take out. Serious defects such as tissue hyperplasia and wire breakage due to corrosion.
  • DRAWINGS BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a schematic view showing the structure of an uncoated stent of the present invention.
  • Fig. 2 is a second schematic view showing the structure of the uncoated stent of the present invention.
  • Fig. 3 is a schematic view showing the structure of a stent of the film of the present invention.
  • Fig. 4 is a second schematic view showing the structure of the stent of the film of the present invention.
  • Fig. 5 is a schematic view showing the structure of the stent of the present invention implanted into a lesion in a human lumen.
  • Fig. 6 is a second schematic view showing the structure of the stent of the present invention implanted into the lumen of the human body. detailed description
  • a hybrid structure tubular recoverable stent (Fig. 1, 2), the stent 1 is a tubular network composed of a cylindrical portion 2 and a distal end portion 3 of a columnar structure, and is composed of a biological phase Woven fabric with good properties.
  • the cylindrical portion 2 and the end portions 3 can be mixed by hand weaving and mechanical weaving.
  • the mesh shapes of the two parts can be the same or different, and the cylindrical portion 2 has a scaly structure, as shown in FIG.
  • the cylindrical portion and the one end portion of each of the cylinders have a scaly structure, and the cylindrical portion of Fig. 2 has a scaly structure.
  • the end portions at both ends are annular structures 4 having a certain rotation angle (which may be 45 degrees or 60 degrees, etc.).
  • the end portion 3 is an annular structure 4 having a certain rotation angle which is wound by a wire (the upper end of Fig. 1, the upper and lower ends of Fig. 2)
  • the annular structure 4 may be wound into a plurality of shapes by a wire material, and may be wound one or more times, and one or more of the ends having sufficient strength may be passed through the outermost end of the ring structure.
  • the wire 5 is knotted at the joint of the recovery wire 5 to form a knot 7, and the number of knots may be one or more, as needed.
  • the cylindrical portion 2 and the end portions 3 at both ends may be a split structure or a unitary structure, and the split structures are connected together in a specific manner, and the combination of the two depends on different lesion conditions.
  • the structure of the end portions 3 at both ends may be a plurality of shapes such as a bell mouth, a ball head, a cup mouth, or a combination of any two.
  • the stent Before use, the stent is compressed and fixed in the delivery device. During use, the stent 1 is delivered to the lesion and released by the guidewire, X-ray or auxiliary monitoring of the endoscope, for example, the stenosis in the lumen. The stent is accurately fixed in the lesion in the lumen, gradually recovering the shape and expanding the lumen, and can fit the wall well ( Figure 5, 6). If the head end portion 3 is hand-woven, before the recovery of the bracket, the take-out device is transported to the rack placement position by a specific means, such as a sampling pliers, etc., after the knot 7 of the recovery thread 5 is clamped, the recovery thread 5 is pulled.
  • a specific means such as a sampling pliers, etc.
  • a hybrid structure tubular retrievable stent (Fig. 3, 4), the stent 1 is composed of a cylindrical portion 2 and a terminal portion 3 at both ends, and has good biocompatibility.
  • the wire is woven.
  • the cylindrical portion 2 and the end portions 3 at both ends may be a mixture of a hand-woven and a mechanical weaving process, and the mesh shape of the cylindrical portion 2 may be the same or different.
  • the end portion 3 is composed of a ring-shaped structure 4 having a certain rotation angle formed by winding a wire material, and the annular structure 4 can be wound into a plurality of shapes by the wire material.
  • the cylindrical portion 2 and the two end portions 3 may be a split structure or a unitary structure, and the split structures are connected together in a specific manner, such as by welding, soft wire or film connection, and the combination of the two according to different lesions. And set.
  • the structure of the both end portions 3 may be a combination of various shapes such as a bell mouth, a ball head, and a cup mouth.
  • the inner/outer surface of the stent 1 can be partially or completely coated, and the coating material 4 is a polymer material with good biocompatibility, and the filming manner of the two ends and the main body.
  • the rest are the same as in the first embodiment.
  • the stent Before use, the stent is compressed and fixed in the delivery device. During use, the stent 1 is delivered to the lesion and released by the guidewire, X-ray or auxiliary monitoring of the endoscope, for example, the stenosis in the lumen. The stent is accurately fixed in the lesion in the lumen, gradually recovering the shape and expanding the lumen, and can fit the wall well (Figure 5, 6).
  • the take-out device is transported to the rack placement position by a specific means, such as a sampling clamp, etc., after clamping the knot of the recovery line 5, pull the recovery line to tighten the head end of the bracket.
  • a specific means such as a sampling clamp, etc.
  • the state of the end of the stent is still observed under the auxiliary monitoring of the X-ray or the endoscope. After confirmation, the stent is pulled out of the lumen and the recovery is completed.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

La présente invention concerne une endoprothèse endoluminale recyclable structurale hybride qui (1) est constituée d'un corps principal de colonne (2) et d'extrémités (3) raccordées aux deux extrémités du corps principal de colonne (2). L'endoprothèse est caractérisée en ce que le corps principal de colonne (2) est une structure imbriquée qui est formée au moyen d'un tissage, le sommet d'au moins une des deux extrémités (3) étant pourvu d'au moins un cercle de structures annulaires (4), un filetage recyclé (5) étant installé de façon pénétrante dans les structures annulaires (4), et une jonction du filetage recyclé (5) étant nouée pour former un nœud (7). L'endoprothèse résout les inconvénients d'une endoprothèse conventionnelle, et présente les avantages d'une structure simple et nouvelle et similaire.
PCT/CN2012/080375 2011-12-14 2012-08-20 Endoprothèse endoluminale recyclable structurale hybride WO2013086868A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110417078.X 2011-12-14
CN201110417078XA CN102488579A (zh) 2011-12-14 2011-12-14 混合式结构管腔内可回收支架

Publications (1)

Publication Number Publication Date
WO2013086868A1 true WO2013086868A1 (fr) 2013-06-20

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PCT/CN2012/080375 WO2013086868A1 (fr) 2011-12-14 2012-08-20 Endoprothèse endoluminale recyclable structurale hybride

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CN (1) CN102488579A (fr)
WO (1) WO2013086868A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11564787B2 (en) 2019-11-18 2023-01-31 Boston Scientific Scimed, Inc. Stent with improved anti-migration properties
US11678970B2 (en) 2018-12-04 2023-06-20 Boston Scientific Scimed, Inc. Device for anastomotic bypass

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102488579A (zh) * 2011-12-14 2012-06-13 南京微创医学科技有限公司 混合式结构管腔内可回收支架
KR101498584B1 (ko) * 2013-05-15 2015-03-04 주식회사 스텐다드싸이텍 이동방지용 스텐트
CN103750929B (zh) * 2014-01-10 2015-11-25 孙常友 一种x光透视下使用的镍钛记忆合金食管支架安放回收装置
CN104367399B (zh) * 2014-11-05 2017-01-18 南京微创医学科技股份有限公司 一种超顺应性的可回收覆膜分段支架及其制备方法
CN105213077B (zh) * 2015-08-19 2018-02-02 中国人民解放军第二军医大学 一种覆网支架
WO2018089560A1 (fr) * 2016-11-09 2018-05-17 Boston Scientific Scimed, Inc. Système d'ancrage d'endoprothèse vasculaire
CN113382694A (zh) * 2019-01-31 2021-09-10 贝克顿·迪金森公司 混合框架腔内假体及其方法

Citations (6)

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Publication number Priority date Publication date Assignee Title
CN2617400Y (zh) * 2003-05-20 2004-05-26 南京微创医学科技有限公司 内放疗用支架
EP1518518A2 (fr) * 2003-09-25 2005-03-30 Karel Volenec Stent pour arrêter le saignement variceal oesophagien
CN101856277A (zh) * 2009-04-10 2010-10-13 王涛 一种可回收的单向活瓣覆膜支架
WO2011094586A1 (fr) * 2010-01-29 2011-08-04 Cook Medical Technologies LLC. Structure d'aplatissement pour réduire le diamètre d'un stent
CN102488579A (zh) * 2011-12-14 2012-06-13 南京微创医学科技有限公司 混合式结构管腔内可回收支架
CN202426690U (zh) * 2011-12-14 2012-09-12 南京微创医学科技有限公司 混合式结构管腔内可回收支架

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2617400Y (zh) * 2003-05-20 2004-05-26 南京微创医学科技有限公司 内放疗用支架
EP1518518A2 (fr) * 2003-09-25 2005-03-30 Karel Volenec Stent pour arrêter le saignement variceal oesophagien
CN101856277A (zh) * 2009-04-10 2010-10-13 王涛 一种可回收的单向活瓣覆膜支架
WO2011094586A1 (fr) * 2010-01-29 2011-08-04 Cook Medical Technologies LLC. Structure d'aplatissement pour réduire le diamètre d'un stent
CN102488579A (zh) * 2011-12-14 2012-06-13 南京微创医学科技有限公司 混合式结构管腔内可回收支架
CN202426690U (zh) * 2011-12-14 2012-09-12 南京微创医学科技有限公司 混合式结构管腔内可回收支架

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11678970B2 (en) 2018-12-04 2023-06-20 Boston Scientific Scimed, Inc. Device for anastomotic bypass
US11564787B2 (en) 2019-11-18 2023-01-31 Boston Scientific Scimed, Inc. Stent with improved anti-migration properties

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