WO2011098689A2 - Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) - Google Patents
Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) Download PDFInfo
- Publication number
- WO2011098689A2 WO2011098689A2 PCT/FR2011/000080 FR2011000080W WO2011098689A2 WO 2011098689 A2 WO2011098689 A2 WO 2011098689A2 FR 2011000080 W FR2011000080 W FR 2011000080W WO 2011098689 A2 WO2011098689 A2 WO 2011098689A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- agomelatine
- ocd
- treatment
- obsessive compulsive
- compulsive disorder
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Definitions
- Agomelatine or N- [2- (7-methoxy-1-naphthyl) ethyl] acetamide has the dual feature of being on the one hand agonist on the receptors of the melatoninergic system and on the other hand antagonist of the 5-HT receptor 2C . These properties give it an activity in the central nervous system and more particularly in the treatment of major depression, seasonal depression, sleep disorders, cardiovascular pathologies, pathologies of the digestive system, insomnia and fatigue due to jet lag, appetite and obesity disorders.
- ⁇ for diluents: lactose, dextrose, sucrose, mannitol, sorbitol, cellulose, glycerin,
- ⁇ for the binders magnesium aluminum silicate, starch, gelatin, tragacanth, methylcellulose, sodium carboxymethylcellulose and polyvinylpyrrolidone,
- the appropriate dosage varies according to the sex, age and weight of the patient, the route of administration, the nature of the condition and any associated treatments and ranges from 1 mg to 50 mg of agomelatine per 24 hours. .
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2789082A CA2789082C (fr) | 2010-02-11 | 2011-02-10 | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) |
LTEP11708533.2T LT2533774T (lt) | 2010-02-11 | 2011-02-10 | Agomelatino panaudojimas gamyboje vaistų, skirtų obsesinio kompulsinio sutrikimo gydymui |
DK11708533.2T DK2533774T3 (en) | 2010-02-11 | 2011-02-10 | USE OF AGOMELATIN FOR THE PREPARATION OF MEDICINALS FOR THE TREATMENT OF OBSESSIVE-COMPULSIVE CONDITION (OCD) |
EA201201123A EA023473B1 (ru) | 2010-02-11 | 2011-02-10 | Применение агомелатина для получения лекарственных средств, предназначенных для лечения обсессивно-компульсивного расстройства (окр) |
AU2011214190A AU2011214190B2 (en) | 2010-02-11 | 2011-02-10 | Use of agomelatine for the preparation of drugs for treating obsessive compulsive disorder (OCD) |
SI201131444T SI2533774T1 (en) | 2010-02-11 | 2011-02-10 | APPLICATION OF AGOMELATINES FOR PREPARATION OF MEDICINAL PRODUCTS FOR TREATMENT OF A VITAL COMPULSIVE DISEASE (OKM) |
BR112012020169-7A BR112012020169A2 (pt) | 2010-02-11 | 2011-02-10 | utilização da agomelatina para a obtenção de medicamentos destinados ao tratamento do transtorno obsessivo compulsivo (toc). |
JP2012552440A JP5634529B2 (ja) | 2010-02-11 | 2011-02-10 | 強迫性障害(ocd)処置用の薬剤の製造のためのアゴメラチンの使用 |
MX2012009087A MX2012009087A (es) | 2010-02-11 | 2011-02-10 | Utilizacion de la agomelatina para la obtencion de medicamentos destinados al tratamiento del transtorno obsesivo compulsivo (toc). |
UAA201210538A UA104368C2 (ru) | 2010-02-11 | 2011-02-10 | Применение агомелатина как единственного агента для получения лекарственного средства, предназначенного для лечения обсессивно-компульсивного расстройства (окр) |
RS20180216A RS56932B1 (sr) | 2010-02-11 | 2011-02-10 | Upotreba agomelatina za pripremu lekova za lečenje opsesivno kompulzivnog poremećaja (okp) |
US13/578,383 US20120309838A1 (en) | 2010-02-11 | 2011-02-10 | Use of agomelatine in obtaining medicaments intended for the treatment of obsessive-compulsive disorder (ocd) |
SG2012055505A SG182748A1 (en) | 2010-02-11 | 2011-02-10 | Use of agomelatine for the preparation of drugs for treating obsessive compulsive disorder (ocd) |
NO11708533A NO2533774T3 (lt) | 2010-02-11 | 2011-02-10 | |
ES11708533.2T ES2667856T3 (es) | 2010-02-11 | 2011-02-10 | Utilización de agomelatina para la obtención de medicamentos destinados al tratamiento del trastorno obsesivo compulsivo (TOC) |
MEP-2018-36A ME03047B (me) | 2010-02-11 | 2011-02-10 | Upotreba agomelatina za pripravu lijekova za liječenje opsesivno-kompulzivnog poremećaja ( ocd) |
CN201180007930.4A CN102781437B (zh) | 2010-02-11 | 2011-02-10 | 阿戈美拉汀在得到预定治疗强迫性障碍(ocd)的药物中的用途 |
MA35133A MA34129B1 (fr) | 2010-02-11 | 2011-02-10 | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) |
EP11708533.2A EP2533774B1 (fr) | 2010-02-11 | 2011-02-10 | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) |
PL11708533T PL2533774T3 (pl) | 2010-02-11 | 2011-02-10 | Zastosowanie agomelatyny do wytwarzania leku przeznaczonego do leczenia zaburzenia obsesyjno-kompulsyjnego (OCD) |
NZ601452A NZ601452A (en) | 2010-02-11 | 2011-02-10 | Use of agomelatine in obtaining medicaments intended for the treatment of obsessive-compulsive disorder (ocd) |
ZA2012/05566A ZA201205566B (en) | 2010-02-11 | 2012-07-24 | Use of agomelatine in obtaining medicament intended for the treatment of obsessive compulsive disorder (ocd) |
HK13105666.7A HK1177897A1 (en) | 2010-02-11 | 2013-05-13 | Use of agomelatine for the preparation of drugs for treating obsessive compulsive disorder (ocd) (ocd) |
CY20181100139T CY1120009T1 (el) | 2010-02-11 | 2018-02-05 | Χρηση αγομελατινης για την ληψη φαρμακων που προοριζονται για την θεραπεια ιδεο-ψυχαναγκαστικης διαταραχης (toc) |
HRP20180537TT HRP20180537T1 (hr) | 2010-02-11 | 2018-04-03 | Uporaba agomelatina za pripravu lijekova za liječenje opsesivno-kompulzivnog poremećaja (ocd) |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1000560A FR2956031B1 (fr) | 2010-02-11 | 2010-02-11 | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) |
FR1000560 | 2010-02-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011098689A2 true WO2011098689A2 (fr) | 2011-08-18 |
WO2011098689A3 WO2011098689A3 (fr) | 2011-12-08 |
Family
ID=42244669
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2011/000080 WO2011098689A2 (fr) | 2010-02-11 | 2011-02-10 | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) |
Country Status (34)
Country | Link |
---|---|
US (1) | US20120309838A1 (lt) |
EP (1) | EP2533774B1 (lt) |
JP (1) | JP5634529B2 (lt) |
KR (1) | KR20120117936A (lt) |
CN (1) | CN102781437B (lt) |
AR (1) | AR080150A1 (lt) |
AU (1) | AU2011214190B2 (lt) |
BR (1) | BR112012020169A2 (lt) |
CA (1) | CA2789082C (lt) |
CY (1) | CY1120009T1 (lt) |
DK (1) | DK2533774T3 (lt) |
EA (1) | EA023473B1 (lt) |
ES (1) | ES2667856T3 (lt) |
FR (1) | FR2956031B1 (lt) |
GE (1) | GEP20166456B (lt) |
HK (1) | HK1177897A1 (lt) |
HR (1) | HRP20180537T1 (lt) |
HU (1) | HUE037098T2 (lt) |
LT (1) | LT2533774T (lt) |
MA (1) | MA34129B1 (lt) |
ME (1) | ME03047B (lt) |
MX (1) | MX2012009087A (lt) |
MY (1) | MY158112A (lt) |
NO (1) | NO2533774T3 (lt) |
NZ (1) | NZ601452A (lt) |
PL (1) | PL2533774T3 (lt) |
PT (1) | PT2533774T (lt) |
RS (1) | RS56932B1 (lt) |
SG (1) | SG182748A1 (lt) |
SI (1) | SI2533774T1 (lt) |
TR (1) | TR201802155T4 (lt) |
UA (1) | UA104368C2 (lt) |
WO (1) | WO2011098689A2 (lt) |
ZA (1) | ZA201205566B (lt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2645223T3 (es) * | 2013-06-06 | 2017-12-04 | Zentiva, K.S. | Formulaciones de agomelatina que comprenden agomelatina en forma de co-cristales |
CN103655499B (zh) * | 2013-12-23 | 2015-07-22 | 天津泰普药品科技发展有限公司 | 一种稳定的晶x型阿戈美拉汀片剂及其制备方法 |
KR102039582B1 (ko) | 2018-12-12 | 2019-11-01 | 주식회사 라파스 | 인장 공정으로 제조하기에 적합한 마이크로니들 재료의 적합성 시험 방법 및 이를 포함하는 마이크로니들 제조 방법 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0447285A1 (fr) | 1990-02-27 | 1991-09-18 | Adir Et Compagnie | Nouveaux dérivés à structure naphtalénique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
EP1564202A1 (fr) | 2004-02-13 | 2005-08-17 | Les Laboratoires Servier | Nouveau procédé de synthèse et nouvelle forme cristalline de l'agomelatine ainsi que les compositions pharmaceutiques qui la contiennent |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5618824A (en) * | 1994-03-09 | 1997-04-08 | Merrell Pharmaceuticals Inc. | Treatment of obsessive-compulsive disorders with 5-HT2 antagonists |
AR047553A1 (es) * | 2003-07-04 | 2006-01-25 | Lundbeck & Co As H | La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina |
EP1858515A2 (en) * | 2005-03-04 | 2007-11-28 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders |
FR2899472B1 (fr) * | 2006-04-07 | 2008-09-12 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee |
KR20090029200A (ko) * | 2006-05-22 | 2009-03-20 | 반다 파마슈티칼즈, 인코퍼레이티드. | 우울증 질환에 대한 치료 |
WO2008035177A2 (en) * | 2006-09-18 | 2008-03-27 | Copharm | Combination of mt1 and mt2 melatonin receptor agonists and a norepinephrine/dopamine reuptake inhibitor |
-
2010
- 2010-02-11 FR FR1000560A patent/FR2956031B1/fr not_active Expired - Fee Related
-
2011
- 2011-02-09 AR ARP110100406A patent/AR080150A1/es unknown
- 2011-02-10 MX MX2012009087A patent/MX2012009087A/es not_active Application Discontinuation
- 2011-02-10 SI SI201131444T patent/SI2533774T1/en unknown
- 2011-02-10 CN CN201180007930.4A patent/CN102781437B/zh not_active Expired - Fee Related
- 2011-02-10 JP JP2012552440A patent/JP5634529B2/ja not_active Expired - Fee Related
- 2011-02-10 NO NO11708533A patent/NO2533774T3/no unknown
- 2011-02-10 ES ES11708533.2T patent/ES2667856T3/es active Active
- 2011-02-10 ME MEP-2018-36A patent/ME03047B/me unknown
- 2011-02-10 CA CA2789082A patent/CA2789082C/fr not_active Expired - Fee Related
- 2011-02-10 UA UAA201210538A patent/UA104368C2/ru unknown
- 2011-02-10 WO PCT/FR2011/000080 patent/WO2011098689A2/fr active Application Filing
- 2011-02-10 EA EA201201123A patent/EA023473B1/ru not_active IP Right Cessation
- 2011-02-10 DK DK11708533.2T patent/DK2533774T3/en active
- 2011-02-10 PL PL11708533T patent/PL2533774T3/pl unknown
- 2011-02-10 HU HUE11708533A patent/HUE037098T2/hu unknown
- 2011-02-10 KR KR1020127023793A patent/KR20120117936A/ko not_active Application Discontinuation
- 2011-02-10 MA MA35133A patent/MA34129B1/fr unknown
- 2011-02-10 LT LTEP11708533.2T patent/LT2533774T/lt unknown
- 2011-02-10 AU AU2011214190A patent/AU2011214190B2/en not_active Ceased
- 2011-02-10 GE GEAP201112854A patent/GEP20166456B/en unknown
- 2011-02-10 RS RS20180216A patent/RS56932B1/sr unknown
- 2011-02-10 US US13/578,383 patent/US20120309838A1/en not_active Abandoned
- 2011-02-10 NZ NZ601452A patent/NZ601452A/en not_active IP Right Cessation
- 2011-02-10 SG SG2012055505A patent/SG182748A1/en unknown
- 2011-02-10 BR BR112012020169-7A patent/BR112012020169A2/pt not_active IP Right Cessation
- 2011-02-10 EP EP11708533.2A patent/EP2533774B1/fr active Active
- 2011-02-10 TR TR2018/02155T patent/TR201802155T4/tr unknown
- 2011-02-10 MY MYPI2012700497A patent/MY158112A/en unknown
- 2011-02-10 PT PT117085332T patent/PT2533774T/pt unknown
-
2012
- 2012-07-24 ZA ZA2012/05566A patent/ZA201205566B/en unknown
-
2013
- 2013-05-13 HK HK13105666.7A patent/HK1177897A1/xx not_active IP Right Cessation
-
2018
- 2018-02-05 CY CY20181100139T patent/CY1120009T1/el unknown
- 2018-04-03 HR HRP20180537TT patent/HRP20180537T1/hr unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0447285A1 (fr) | 1990-02-27 | 1991-09-18 | Adir Et Compagnie | Nouveaux dérivés à structure naphtalénique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
EP1564202A1 (fr) | 2004-02-13 | 2005-08-17 | Les Laboratoires Servier | Nouveau procédé de synthèse et nouvelle forme cristalline de l'agomelatine ainsi que les compositions pharmaceutiques qui la contiennent |
Non-Patent Citations (2)
Title |
---|
"DSM IV - Manuel Diagnostique et Statistique des Troubles Mentaux", AMERICAN PSYCHIATRIC ASSOCIATION |
KAPLAN A. ET AL., PSYCHIATRIC SERVICES, vol. 54, no. 8, 2003 |
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