HRP20180537T1 - Uporaba agomelatina za pripravu lijekova za liječenje opsesivno-kompulzivnog poremećaja (ocd) - Google Patents
Uporaba agomelatina za pripravu lijekova za liječenje opsesivno-kompulzivnog poremećaja (ocd) Download PDFInfo
- Publication number
- HRP20180537T1 HRP20180537T1 HRP20180537TT HRP20180537T HRP20180537T1 HR P20180537 T1 HRP20180537 T1 HR P20180537T1 HR P20180537T T HRP20180537T T HR P20180537TT HR P20180537 T HRP20180537 T HR P20180537T HR P20180537 T1 HRP20180537 T1 HR P20180537T1
- Authority
- HR
- Croatia
- Prior art keywords
- agomelatine
- ocd
- compulsive disorder
- obsessive
- pharmaceutically acceptable
- Prior art date
Links
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 title claims 9
- YJYPHIXNFHFHND-UHFFFAOYSA-N agomelatine Chemical compound C1=CC=C(CCNC(C)=O)C2=CC(OC)=CC=C21 YJYPHIXNFHFHND-UHFFFAOYSA-N 0.000 title claims 6
- 229960002629 agomelatine Drugs 0.000 title claims 6
- 229940079593 drug Drugs 0.000 title claims 2
- 239000003814 drug Substances 0.000 title claims 2
- 239000002253 acid Substances 0.000 claims 3
- 239000003513 alkali Substances 0.000 claims 3
- 150000004677 hydrates Chemical class 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (6)
1. Uporaba agomclatina ili N-[2-(7-metoksi-1-naftil)ctil]acetamida ili jednog od njihovih hidrata, kristalnih oblika i adicijskih soli s farmaceutski prihvatljivom kiselinom ili lužinom, kao jedini djelatni sastojak, naznačena time, da se koristi za dobivanje lijeka za liječenje opsesivno-kompulzivnog poremećaja (OCD).
2. Uporaba u skladu s patentnim zahtjevom 1, naznačena time, da je agomelatin dobiven u kristalnom obliku II kako je opisano u patentnoj prijavi EP 1564202.
3. Farmaceutski pripravci koji se sastoje od agomelatina ili jednog od njegovih hidrata, kristalnih oblika i adicijskih soli s farmaceutski prihvatljivom kiselinom ili lužinom, sam ili u kombinaciji s jednim ili više farmaceutski prihvatljivih ekscipijensa, naznačno time, da se koriste u liječenju opsesivno-kompulzivnog poremećaja (OCD).
4. Farmaceutski pripravak za uporabu u skladu s patentnim zatjevom 3, naznačen time, daje agomelatin dobiven u kristalnom obliku II kako je opisano u patentnoj prijavi EP 1564202.
5. Agomelatin ili N-[2-(7-metoksi-1-naftil)etil]acctamid ili jedan od njihovih hidrata, kristalnih oblika kao i njihovih adicijskih soli s farmaceutski prihvatljivom kiselinom ili lužinom, naznačen time, da se koristi u liječenju opsesivno-kompulzivnog poremećaja (OCD).
6. Kristalni oblik II agomelatina kako je opisan u patentnoj prijavi EP 1564202, naznačen time, da je za uporabu u liječenju opscsivno-kompulzivnog poremećaja (OCD).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1000560A FR2956031B1 (fr) | 2010-02-11 | 2010-02-11 | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) |
| PCT/FR2011/000080 WO2011098689A2 (fr) | 2010-02-11 | 2011-02-10 | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) |
| EP11708533.2A EP2533774B1 (fr) | 2010-02-11 | 2011-02-10 | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20180537T1 true HRP20180537T1 (hr) | 2018-05-04 |
Family
ID=42244669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20180537TT HRP20180537T1 (hr) | 2010-02-11 | 2018-04-03 | Uporaba agomelatina za pripravu lijekova za liječenje opsesivno-kompulzivnog poremećaja (ocd) |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US20120309838A1 (hr) |
| EP (1) | EP2533774B1 (hr) |
| JP (1) | JP5634529B2 (hr) |
| KR (1) | KR20120117936A (hr) |
| CN (1) | CN102781437B (hr) |
| AR (1) | AR080150A1 (hr) |
| AU (1) | AU2011214190B2 (hr) |
| BR (1) | BR112012020169A2 (hr) |
| CA (1) | CA2789082C (hr) |
| CY (1) | CY1120009T1 (hr) |
| DK (1) | DK2533774T3 (hr) |
| EA (1) | EA023473B1 (hr) |
| ES (1) | ES2667856T3 (hr) |
| FR (1) | FR2956031B1 (hr) |
| GE (1) | GEP20166456B (hr) |
| HK (1) | HK1177897A1 (hr) |
| HR (1) | HRP20180537T1 (hr) |
| HU (1) | HUE037098T2 (hr) |
| LT (1) | LT2533774T (hr) |
| MA (1) | MA34129B1 (hr) |
| ME (1) | ME03047B (hr) |
| MX (1) | MX2012009087A (hr) |
| MY (1) | MY158112A (hr) |
| NO (1) | NO2533774T3 (hr) |
| NZ (1) | NZ601452A (hr) |
| PL (1) | PL2533774T3 (hr) |
| PT (1) | PT2533774T (hr) |
| RS (1) | RS56932B1 (hr) |
| SG (1) | SG182748A1 (hr) |
| SI (1) | SI2533774T1 (hr) |
| TR (1) | TR201802155T4 (hr) |
| UA (1) | UA104368C2 (hr) |
| WO (1) | WO2011098689A2 (hr) |
| ZA (1) | ZA201205566B (hr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE036989T2 (hu) * | 2013-06-06 | 2018-08-28 | Zentiva Ks | Agomelatin készítmény, amely agomelatint ko-kristály formájában tartalmaz |
| CN103655499B (zh) * | 2013-12-23 | 2015-07-22 | 天津泰普药品科技发展有限公司 | 一种稳定的晶x型阿戈美拉汀片剂及其制备方法 |
| KR102039582B1 (ko) | 2018-12-12 | 2019-11-01 | 주식회사 라파스 | 인장 공정으로 제조하기에 적합한 마이크로니들 재료의 적합성 시험 방법 및 이를 포함하는 마이크로니들 제조 방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2658818B1 (fr) | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5618824A (en) * | 1994-03-09 | 1997-04-08 | Merrell Pharmaceuticals Inc. | Treatment of obsessive-compulsive disorders with 5-HT2 antagonists |
| AR047553A1 (es) * | 2003-07-04 | 2006-01-25 | Lundbeck & Co As H | La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina |
| FR2866335B1 (fr) * | 2004-02-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
| JP2008531714A (ja) * | 2005-03-04 | 2008-08-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 不安障害の治療用及び／又は予防用の医薬組成物 |
| FR2899472B1 (fr) * | 2006-04-07 | 2008-09-12 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee |
| MX2008014843A (es) * | 2006-05-22 | 2008-12-05 | Vanda Pharmaceuticals Inc | Tratamiento de trastornos depresivos. |
| WO2008035177A2 (en) * | 2006-09-18 | 2008-03-27 | Copharm | Combination of mt1 and mt2 melatonin receptor agonists and a norepinephrine/dopamine reuptake inhibitor |
-
2010
- 2010-02-11 FR FR1000560A patent/FR2956031B1/fr not_active Expired - Fee Related
-
2011
- 2011-02-09 AR ARP110100406A patent/AR080150A1/es unknown
- 2011-02-10 AU AU2011214190A patent/AU2011214190B2/en not_active Ceased
- 2011-02-10 PL PL11708533T patent/PL2533774T3/pl unknown
- 2011-02-10 CA CA2789082A patent/CA2789082C/fr not_active Expired - Fee Related
- 2011-02-10 GE GEAP201112854A patent/GEP20166456B/en unknown
- 2011-02-10 SI SI201131444T patent/SI2533774T1/en unknown
- 2011-02-10 TR TR2018/02155T patent/TR201802155T4/tr unknown
- 2011-02-10 EA EA201201123A patent/EA023473B1/ru not_active IP Right Cessation
- 2011-02-10 NO NO11708533A patent/NO2533774T3/no unknown
- 2011-02-10 HU HUE11708533A patent/HUE037098T2/hu unknown
- 2011-02-10 EP EP11708533.2A patent/EP2533774B1/fr active Active
- 2011-02-10 MA MA35133A patent/MA34129B1/fr unknown
- 2011-02-10 JP JP2012552440A patent/JP5634529B2/ja not_active Expired - Fee Related
- 2011-02-10 UA UAA201210538A patent/UA104368C2/ru unknown
- 2011-02-10 NZ NZ601452A patent/NZ601452A/en not_active IP Right Cessation
- 2011-02-10 RS RS20180216A patent/RS56932B1/sr unknown
- 2011-02-10 DK DK11708533.2T patent/DK2533774T3/en active
- 2011-02-10 CN CN201180007930.4A patent/CN102781437B/zh not_active Expired - Fee Related
- 2011-02-10 LT LTEP11708533.2T patent/LT2533774T/lt unknown
- 2011-02-10 WO PCT/FR2011/000080 patent/WO2011098689A2/fr active Application Filing
- 2011-02-10 ES ES11708533.2T patent/ES2667856T3/es active Active
- 2011-02-10 SG SG2012055505A patent/SG182748A1/en unknown
- 2011-02-10 MX MX2012009087A patent/MX2012009087A/es not_active Application Discontinuation
- 2011-02-10 US US13/578,383 patent/US20120309838A1/en not_active Abandoned
- 2011-02-10 PT PT117085332T patent/PT2533774T/pt unknown
- 2011-02-10 KR KR1020127023793A patent/KR20120117936A/ko not_active Application Discontinuation
- 2011-02-10 ME MEP-2018-36A patent/ME03047B/me unknown
- 2011-02-10 BR BR112012020169-7A patent/BR112012020169A2/pt not_active IP Right Cessation
- 2011-02-10 MY MYPI2012700497A patent/MY158112A/en unknown
-
2012
- 2012-07-24 ZA ZA2012/05566A patent/ZA201205566B/en unknown
-
2013
- 2013-05-13 HK HK13105666.7A patent/HK1177897A1/xx not_active IP Right Cessation
-
2018
- 2018-02-05 CY CY20181100139T patent/CY1120009T1/el unknown
- 2018-04-03 HR HRP20180537TT patent/HRP20180537T1/hr unknown
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