WO2010019016A3 - 산삼 또는 인삼을 포함한 인삼류의 형성층 유래 식물줄기세포주를 유효성분으로 함유하는 간질환의 예방 또는 치료용 조성물 - Google Patents

산삼 또는 인삼을 포함한 인삼류의 형성층 유래 식물줄기세포주를 유효성분으로 함유하는 간질환의 예방 또는 치료용 조성물 Download PDF

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WO2010019016A3
WO2010019016A3 PCT/KR2009/004563 KR2009004563W WO2010019016A3 WO 2010019016 A3 WO2010019016 A3 WO 2010019016A3 KR 2009004563 W KR2009004563 W KR 2009004563W WO 2010019016 A3 WO2010019016 A3 WO 2010019016A3
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ginseng
liver diseases
cambium
cell lines
lines derived
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PCT/KR2009/004563
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English (en)
French (fr)
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WO2010019016A2 (ko
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진영우
이은경
임민정
김영미
홍선미
장미옥
구인숙
최금이
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주식회사 운화바이오텍
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Priority to US13/058,949 priority Critical patent/US20120189660A1/en
Priority to CA2734101A priority patent/CA2734101A1/en
Priority to CN200980135446.2A priority patent/CN102316883B/zh
Priority to EP09806878A priority patent/EP2335712A4/en
Priority to AU2009280402A priority patent/AU2009280402A1/en
Priority to JP2011522914A priority patent/JP2011530583A/ja
Publication of WO2010019016A2 publication Critical patent/WO2010019016A2/ko
Publication of WO2010019016A3 publication Critical patent/WO2010019016A3/ko
Priority to US13/863,829 priority patent/US9289457B2/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H4/00Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
    • A01H4/005Methods for micropropagation; Vegetative plant propagation using cell or tissue culture techniques
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Environmental Sciences (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
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Abstract

본 발명은 산삼 또는 인삼을 포함하는 인삼류(Panax ginseng)의 형성층 유래 동질적인 세포주, 그 파쇄물, 그 추출물 및 그 배양물 중 어느 하나 이상을 유효성분으로 함유하는 간질환의 예방 또는 치료용 조성물에 관한 것이다. 본 발명에 따른 인삼류의 형성층 유래 동질적인 세포주, 그 파쇄물, 그 추출물 및 그 배양물은 기존 간질환 치료제의 부작용을 최소화하여 인체에 안전하면서도, 간염 바이러스에 대한 s 항체 (HBsAb) 및 e 항체(HBeAb)를 증가시키는 효과가 있으며, 간염 바이러스의 증식을 억제할 수 있으므로, 간질환의 예방 및 치료에 유용하다. 아울러, 간손상 수치를 감소시키는 효과가 있는바, 간기능 개선용 기능성 식품으로서 유용하다.
PCT/KR2009/004563 2008-08-14 2009-08-14 산삼 또는 인삼을 포함한 인삼류의 형성층 유래 식물줄기세포주를 유효성분으로 함유하는 간질환의 예방 또는 치료용 조성물 WO2010019016A2 (ko)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US13/058,949 US20120189660A1 (en) 2008-08-14 2009-08-14 Composition for Preventing or Treating Liver Diseases, Containing Plant Stem Cell Lines Derived from the Cambium of Panax Ginseng Including Mountain Ginseng or Ginseng as Active Ingredient
CA2734101A CA2734101A1 (en) 2008-08-14 2009-08-14 Composition for preventing or treating liver diseases containing plant stem cell lines derived from cambium of panax ginseng including wild ginseng or ginseng as active components
CN200980135446.2A CN102316883B (zh) 2008-08-14 2009-08-14 含有包括野山参或人参的人参类的形成层来源的植物干细胞系作为有效成分的肝疾病的预防或治疗用组合物
EP09806878A EP2335712A4 (en) 2008-08-14 2009-08-14 COMPOSITION FOR THE PREVENTION OR TREATMENT OF LIVER DISEASES CONTAINING VEGETABLE STEM CELL LINES DERIVED FROM PANAX GINSENG CAMBIUM COMPRISING MOUNTAIN GINSENG OR GINSENG AS ACTIVE INGREDIENT
AU2009280402A AU2009280402A1 (en) 2008-08-14 2009-08-14 Composition for preventing or treating liver diseases, containing plant stem cell lines derived from the cambium of Panax ginseng including wild ginseng or ginseng as active components
JP2011522914A JP2011530583A (ja) 2008-08-14 2009-08-14 天然高麗人参または高麗人参を含む高麗人参類の形成層由来植物幹細胞株を有効成分として含有する肝疾患の予防または治療用組成物
US13/863,829 US9289457B2 (en) 2008-08-14 2013-04-16 Composition for preventing or treating liver diseases, containing plant stem cell lines derived from the cambium of Panax ginseng including mountain ginseng or ginseng as active ingredient

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0080124 2008-08-14
KR20080080124 2008-08-14

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/058,949 A-371-Of-International US20120189660A1 (en) 2008-08-14 2009-08-14 Composition for Preventing or Treating Liver Diseases, Containing Plant Stem Cell Lines Derived from the Cambium of Panax Ginseng Including Mountain Ginseng or Ginseng as Active Ingredient
US13/863,829 Continuation US9289457B2 (en) 2008-08-14 2013-04-16 Composition for preventing or treating liver diseases, containing plant stem cell lines derived from the cambium of Panax ginseng including mountain ginseng or ginseng as active ingredient

Publications (2)

Publication Number Publication Date
WO2010019016A2 WO2010019016A2 (ko) 2010-02-18
WO2010019016A3 true WO2010019016A3 (ko) 2010-06-17

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/004563 WO2010019016A2 (ko) 2008-08-14 2009-08-14 산삼 또는 인삼을 포함한 인삼류의 형성층 유래 식물줄기세포주를 유효성분으로 함유하는 간질환의 예방 또는 치료용 조성물

Country Status (9)

Country Link
US (2) US20120189660A1 (ko)
EP (1) EP2335712A4 (ko)
JP (1) JP2011530583A (ko)
KR (1) KR101179171B1 (ko)
CN (1) CN102316883B (ko)
AU (1) AU2009280402A1 (ko)
CA (1) CA2734101A1 (ko)
RU (1) RU2011109257A (ko)
WO (1) WO2010019016A2 (ko)

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EP1951863B1 (en) 2005-10-31 2015-07-08 Unhwa Corporation Stability of secondary metabolite mass production through syncronized plant cell cultures
KR101064518B1 (ko) * 2007-09-21 2011-09-19 주식회사 운화 저장근을 가지는 초본식물의 형성층 유래 식물줄기세포주 및 이의 분리방법
KR101179171B1 (ko) 2008-08-14 2012-09-03 주식회사 운화 산삼 또는 인삼을 포함한 인삼류의 형성층 유래 식물줄기세포주를 유효성분으로 함유하는 간질환의 예방 또는 치료용 조성물
EP2363137A4 (en) 2008-09-30 2012-08-01 Unhwa Corp COMPOSITION FOR THE PREVENTION OR TREATMENT OF AIDS WITH PLANT GINSENG VEGETABLE GAMBLING LINE FROM THE BAMBIUM OF PANAX GINSENG OR GINSENG AS AN ACTIVE SUBSTANCE
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JP6483240B2 (ja) * 2014-08-22 2019-03-13 ウェルキー ホールディングス リミテッドWellkey Holdings Limited 希少ジンセノサイドを高含量で含有する、山参もしくは高麗人参を含む高麗人参類の抽出物または高麗人参類の形成層由来植物幹細胞もしくはその抽出物の製造方法
CN112852707A (zh) * 2019-11-27 2021-05-28 深圳欧珈再生医学抗衰生物工程有限公司 一种花蕾干细胞及提取方法、花蕾干细胞精华液

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Also Published As

Publication number Publication date
KR101179171B1 (ko) 2012-09-03
CN102316883A (zh) 2012-01-11
RU2011109257A (ru) 2012-09-20
WO2010019016A2 (ko) 2010-02-18
US9289457B2 (en) 2016-03-22
CN102316883B (zh) 2014-10-29
US20130202631A1 (en) 2013-08-08
EP2335712A4 (en) 2012-08-01
CA2734101A1 (en) 2010-02-18
KR20100021369A (ko) 2010-02-24
AU2009280402A1 (en) 2010-02-18
EP2335712A2 (en) 2011-06-22
JP2011530583A (ja) 2011-12-22
US20120189660A1 (en) 2012-07-26

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