WO2009066469A1 - 被験物測定用担体およびその製造方法 - Google Patents

被験物測定用担体およびその製造方法 Download PDF

Info

Publication number
WO2009066469A1
WO2009066469A1 PCT/JP2008/003434 JP2008003434W WO2009066469A1 WO 2009066469 A1 WO2009066469 A1 WO 2009066469A1 JP 2008003434 W JP2008003434 W JP 2008003434W WO 2009066469 A1 WO2009066469 A1 WO 2009066469A1
Authority
WO
WIPO (PCT)
Prior art keywords
reactant
analyte
carrier
site
measurement
Prior art date
Application number
PCT/JP2008/003434
Other languages
English (en)
French (fr)
Inventor
Koichi Minami
Hirohiko Tsuzuki
Original Assignee
Fujifilm Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corporation filed Critical Fujifilm Corporation
Priority to US12/744,311 priority Critical patent/US8236575B2/en
Priority to EP08851758.6A priority patent/EP2224241B1/en
Publication of WO2009066469A1 publication Critical patent/WO2009066469A1/ja

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

【課題】被験物測定用担体を、被験物を短時間で、高感度かつ簡便に検出することができるものとする。 【解決手段】被験物と特異的に結合する反応部位（２）および蛍光標識部位（３）を有する第１反応体（４）と、被験物と特異的に結合する反応部位（５）および前記第１反応体（４）の蛍光標識部位（３）から発せられる蛍光を認識する認識部位（６）を有する第２反応体（７）とを、それぞれ被験物と結合し得る位置関係で担体上に固定されているものとする。
PCT/JP2008/003434 2007-11-22 2008-11-21 被験物測定用担体およびその製造方法 WO2009066469A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/744,311 US8236575B2 (en) 2007-11-22 2008-11-21 Carrier for analysis of an analyte and process for producing the same
EP08851758.6A EP2224241B1 (en) 2007-11-22 2008-11-21 Carrier for use in measurement of analyte, and method for production thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-303026 2007-11-22
JP2007303026 2007-11-22

Publications (1)

Publication Number Publication Date
WO2009066469A1 true WO2009066469A1 (ja) 2009-05-28

Family

ID=40667301

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/003434 WO2009066469A1 (ja) 2007-11-22 2008-11-21 被験物測定用担体およびその製造方法

Country Status (4)

Country Link
US (1) US8236575B2 (ja)
EP (1) EP2224241B1 (ja)
JP (1) JP5264421B2 (ja)
WO (1) WO2009066469A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009145326A (ja) * 2007-11-22 2009-07-02 Fujifilm Corp 被験物測定用担体およびその製造方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9487592B2 (en) 2008-10-24 2016-11-08 Fujifilm Corporation Immobilization substrate and method for producing the same
DE102014203266B4 (de) * 2014-02-24 2018-07-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Zusammensetzung mit FRET-Paar in definierter Geometrie
JP6525199B2 (ja) * 2014-11-26 2019-06-05 国立大学法人広島大学 インスリンの検出方法、および、インスリンの検出キット
CN110018142B (zh) * 2019-03-20 2021-10-22 西南交通大学 复合荧光基底、复合荧光基底的制备方法以及应用
TW202337974A (zh) * 2021-08-27 2023-10-01 國立大學法人神戶大學 用於於基材上產率良好地形成空孔之技術之核殼模板分子、粒子

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002311031A (ja) * 2001-04-18 2002-10-23 Sekisui Chem Co Ltd 分子認識蛍光体、それを用いた標的物質の測定方法
JP2006058071A (ja) 2004-08-18 2006-03-02 Fuji Photo Film Co Ltd バイオセンサー
JP2006090781A (ja) 2004-09-22 2006-04-06 Fuji Photo Film Co Ltd バイオセンサー
JP2006138656A (ja) 2004-11-10 2006-06-01 Kyowa Medex Co Ltd 分子インプリントゲル、その製造方法、該分子インプリントゲルを用いる検体中の対象分子の測定方法および対象分子測定用試薬
JP2007040834A (ja) 2005-08-03 2007-02-15 Japan Science & Technology Agency 免疫測定用試薬
JP2007519525A (ja) 2003-12-09 2007-07-19 マーケム コーポレーション 材料にマークされるイメージの領域のレーザによる塗り潰し
JP2007523754A (ja) 2003-04-30 2007-08-23 バイエル・テクノロジー・サービシーズ・ゲーエムベーハー （ｆ）ｒｅｔアッセイに適したコア／シェル・ナノ粒子

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
JP2001519525A (ja) 1997-10-07 2001-10-23 メルク エンド カムパニー インコーポレーテッド Ｆｒｅｔを用いる核内受容体リガンドに関するアッセイ
US6689574B1 (en) * 1997-10-07 2004-02-10 Merck & Co., Inc. Assays for nuclear receptor agonists and antagonists using fluorescence resonance energy transfer
JP2003075443A (ja) * 2001-09-03 2003-03-12 Sekisui Chem Co Ltd 標的物質測定試薬、それを用いた標的物質の測定方法
WO2004106890A2 (en) * 2003-05-22 2004-12-09 Ciphergen Biosystems, Inc. Trace incorporation of fluorescent monomer facilitating quality control of polymerization reactions
EP1704256A4 (en) * 2004-01-13 2008-01-16 Us Genomics Inc DETECTION AND QUANTIFICATION OF ANALYTES IN SOLUTION USING POLYMERS
US20100256062A1 (en) * 2004-12-06 2010-10-07 Howard Tommy E Allelic Variants of Human Factor VIII
WO2007023915A1 (ja) * 2005-08-26 2007-03-01 Japan Science And Technology Agency インプリントポリマーおよびその利用
JP2008083042A (ja) 2006-08-30 2008-04-10 National Institute Of Advanced Industrial & Technology 分子認識素子及び該分子認識素子を用いたバイオセンサ並びに該バイオセンサを用いた測定方法。
BRPI0717416A2 (pt) * 2006-09-21 2013-11-12 Prometheus Lab Inc Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
JP5264421B2 (ja) * 2007-11-22 2013-08-14 富士フイルム株式会社 被験物測定用担体およびその製造方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002311031A (ja) * 2001-04-18 2002-10-23 Sekisui Chem Co Ltd 分子認識蛍光体、それを用いた標的物質の測定方法
JP2007523754A (ja) 2003-04-30 2007-08-23 バイエル・テクノロジー・サービシーズ・ゲーエムベーハー （ｆ）ｒｅｔアッセイに適したコア／シェル・ナノ粒子
JP2007519525A (ja) 2003-12-09 2007-07-19 マーケム コーポレーション 材料にマークされるイメージの領域のレーザによる塗り潰し
JP2006058071A (ja) 2004-08-18 2006-03-02 Fuji Photo Film Co Ltd バイオセンサー
JP2006090781A (ja) 2004-09-22 2006-04-06 Fuji Photo Film Co Ltd バイオセンサー
JP2006138656A (ja) 2004-11-10 2006-06-01 Kyowa Medex Co Ltd 分子インプリントゲル、その製造方法、該分子インプリントゲルを用いる検体中の対象分子の測定方法および対象分子測定用試薬
JP2007040834A (ja) 2005-08-03 2007-02-15 Japan Science & Technology Agency 免疫測定用試薬

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CHEMICAL REVIEW, vol. 105, 2005, pages 1103 - 1169
KAZUKO HIRAYAMA ET AL.: "Bunshi Imprinting-ho ni yoru Lysozyme Igata no Gosei Oyobi sono Suisho Shindoshiki Sensor eno Oyo", JOURNAL OF JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY, vol. 49, no. 1, 2000, pages 29 - 33 *
KIM, J. ET AL.: "Polymeric nanoparticles for protein kinase activity", CHEM COMMUN, no. 13, 2007, pages 1346 - 1348 *
KOICHI MINAMI ET AL.: "Kotai Kahen Ryoiki Danpen o Katsuyo shita Shinki Bunshi Imprinting Gijutsu", SEIKAGAKU, 2008 *
See also references of EP2224241A4
TURNER, N.W. ET AL.: "Formation of protein molecular imprints within Langmuir monolayers: A quartz crystal microbalance study", J COLLOID INTERFACE SCI, vol. 308, no. 1, 2007, pages 71 - 80 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009145326A (ja) * 2007-11-22 2009-07-02 Fujifilm Corp 被験物測定用担体およびその製造方法

Also Published As

Publication number Publication date
EP2224241B1 (en) 2014-04-09
EP2224241A4 (en) 2011-04-20
US20100290954A1 (en) 2010-11-18
EP2224241A1 (en) 2010-09-01
JP5264421B2 (ja) 2013-08-14
US8236575B2 (en) 2012-08-07
JP2009145326A (ja) 2009-07-02

Similar Documents

Publication Publication Date Title
WO2009066469A1 (ja) 被験物測定用担体およびその製造方法
MX2008014293A (es) Metodos de ensayo sin separacion.
WO2002088382A3 (de) Verfahren zur analyse von nukleinsäureketten
AU2004298540A1 (en) Reagent for detecting an analyte
WO2007137060A3 (en) Systems, methods, and apparatus for single molecule sequencing
WO2006080024A3 (en) Device, system and method for in vivo analysis
WO2008036697A3 (en) Methods, systems and apparatus for light concentrating mechanisms
SE0600642L (sv) Fluorescensläsare
WO2009017861A3 (en) Analyte detection using autocatalytic chain reactions
WO2020097138A8 (en) Non-enzymatic glow assays
DE602006011756D1 (de) Komplexformierungs- und -trennungsverfahren
ATE477336T1 (de) Feste oberfläche für biomolekülabgabe und assay mit hoher durchlaufleistung
WO2007103859A3 (en) Methods, products, and kits for identifying an analyte in a sample
GB2431988A (en) Assay device & method
WO2010024609A3 (ko) 단백질분해효소 활성 측정용 나노입자 센서 및 그 제조방법
WO2007087315A3 (en) Method and system for combined raman and libs detection
WO2010004436A3 (en) Enhanced immunoassay sensor
WO2008105812A3 (en) Portable mems-based spectral identification system
WO2008130376A3 (en) Determination of explosives including rdx
WO2019113075A3 (en) Microbial-based biosensors
EP1672082A3 (en) A method for detecting a target substance using a nucleic acid probe
WO2007106802A3 (en) Method for linear amplification of bisulfite converted dna
WO2006044747A3 (en) P27 ubiquitination assay and methods of use
ATE553383T1 (de) Biosensor und verwendung
WO2010121174A3 (en) Chemiluminescent enzyme assay method and compounds

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08851758

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 12744311

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008851758

Country of ref document: EP